Uses and Gratification on eWOM Tourism Information

Yang,Sung-Soo,Huh,Hyang-Jin,Suh,Yong-Kun 세계문화관광학회 2009 Conference Proceedings Vol.10 No.0

This study draw on the uses and gratifications perspective in tourism information research to examine the tourist experience associated with website. The goal of this study is to investigate the extent to eWOM(electronic Word-of-Mouth) using motivation and gratification. In methodological sense, the survey was employed in user of destination search for travel and performed application with AVOVA for analysis. Data collecting method was a convenience sampling with face-to-face interview. A total of 600 questionnaires were collected from the survey and 577 questionnaires were coded for a data for analysis on this study. Data for the study were drawn from the user who have been travel information on eWOM. The findings deriving from this study are followings; First, Perception of using motivation is consist of 5 dimensions such as Self-Development, Information Acquisition, Enjoyment, Community, and Travel Cost. Second, The findings deriving from this study is a statistically significant difference in the relationship between the using dimensions and user propensity of eWOM tourism information. Finally, using motivation was positively related with behavioral intentions of making process.

A comparison of survival outcome of open, total laparoscopic and laparoscopy-assisted vaginal radical hysterectomy in patients with early cervical cancer of stage IB2

( Sul Lee ),( Hyung Joon Yoon ),( Eun Hye Jeon ),( Juseok Yang ),( Yong Jung Song ),( Hyun Jin Roh ),( Sang Hun Lee ),( Byung Su Kwon ),( Ki Hyung Kim ),( Dong Soo Suh ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

Objective: The aim of this study is to evaluate oncologic outcomes of total abdominal radical hysterectomy (TARH), total laparoscopic radical hysterectomy (TLRH) and laparoscopic-assisted radical vaginal hysterectomy (LARVH) in early cervical cancer patients (stage IB2-3, tumor size≥2cm), analyzing the risk factors that may affect the clinical results. Methods: A total of 756 patients underwent radical hysterectomy between 2000 and 2019 from three university hospitals (Pusan National University Hospital, Yang-san Pusan National University Hospital, Ulsan University Hospital) were enrolled. Among them, 172 patients with stage IB2-3 were analyzed retrospectively. Results: Seventy-seven patients were treated with TARH, and 95 were managed via minimally invasive surgery (MIS), consisting of 35 with TLRH and 60 with LARVH. TARH group had better disease five-year disease free survival (DFS) and overall survival (OS) compared with MIS group (86.4% vs. 73.4 for DFS and 91.7 vs. 82.2 for OS), but not statistically significant in both (p=0.058 for DFS and p=0.119 for OS). When TARH and the LARVH group were compared, both five-year DFS and OS were not significant different (86.4 vs 82.2%; p=0.288 for DFS and 91.7 vs 84.4%; p=0.206 for OS). However, when TARH and the TLRH group were compared, TLRH group had significantly worse five-year DFS than TARH (86.4 vs 54.5%; p=0.008), but five-year OS was not significant different (91.7 vs 77.5%; p=0.127). Multivariate analysis showed that LN metastasis and TLRH surgical approaches were an independent prognostic factor for DFS in IB2-3 cervical cancers. Conclusion: Our findings provided the evidence that TLRH surgical approach was associated with worse DFS in IB2-3 cervical cancers but that of LARVH was not. Such results may have important implications of colpotomy method for MIS in cervical cancer.

Could cluster of risk factors predict clinical outcome in patients with acute myocardial infarction?

( Sang Mi Park ),( Hong Nyun Kim ),( Se Yong Jang ),( Myung Hwan Bae ),( Dong Heon Yang ),( Hun Sik Park ),( Yongkeun Cho ),( Shung Chull Chae ),( Jang Hoon Lee ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Purpose: Conventional risk factors are differently contributed to short-term prognosis of acute myocardial infarction (AMI); hypertension and diabetes increase adverse outcome, whereas hyperlipidemia, smoking, and obesity paradoxically decrease adverse outcome of post-MI patients. The aim of this study is to assess whether cluster of conventional risk factors, PARADOCS (Pressure of ARtery Abnormality, Diabetes, Obesity, Cholesterol, Smoking) score, would improve the ability to predict major adverse cardiac events (MACEs) in patients with AMI. Methods: Between November 2005 and July 2011, 24,020 patients (17,232 men; mean age=63.0±12.8) with AMI were analyzed from Korean AMI registry. PARADOCS score was calculated as follows; [number of non-paradoxical risk factors (NRF) -number of paradoxical risk factors (PRF)]+3 in which non-paradoxical risk factors are hypertension and diabetes, and paradoxical risk factors are the rest. The 1-year MACEs were defined as death and non-fatal MI. Results: NRF including hypertension and diabetes were present in 49.6% and 27.0%, whereas PRF including hyperlipidemia, smoking, and obesity were present in 12.3%, 43.0%, and 34.6%, respectively. During the follow-up, 1,409 (5.9%) MACEs occurred. PARADOCS score was significantly higher in patients with 1-year MACEs (3.38±1.03 versus 2.81±1.08, p<0.001). In Cox proportional hazards model, PARADOCS score was an independent predictor of 1-year MACEs (hazards ratio 1.26, 95% confidence interval 1.18-1.34; p<0.001) after adjusting for confounding variables. Patients were categorized into 3 groups according to the PARADOCS score; PARADOCSLOW (0-1, n=2,446), PARADOCSMID (2-3, n=14,594), and PARADOCSHIGH (4-5, n= 6,980). Kaplan-Meier survival curve showed that there were significant differences in the 1-year MACEs among three groups including 3.5% in PARADOCSLOW, 8.5% in PARADOCSMID, and 16.4% in PARADOCSHIGH, respectively (long-rank p<0.001). Conclusions: In post-MI patients, conventional risk factors are differently associated with short-term prognosis, and score of these risk factors, PARADOCS score, can provide useful prognostic information to clinicians.

Optimization of Amylase Production from Bacillus sp. Using Statstics Based Experimental Design

Yong Hyun KIM,Jong Min JEON,Hyun Joong KIM,Da Hye LEE,Hyung Min SEO,Jung Ho KIM,Hyung Joo KIM,Sang Hyun LEE,Yung Hun YANG 한국생물공학회 2013 한국생물공학회 학술대회 Vol.2013 No.10

Influence of Probiotics-Friendly Pig Production on Meat Quality and Physicochemical Characteristics

Sung Yong Chang,Shah Ahmed Belal,Da Rae Kang,Yang Il Choi,Young Hoon Kim,Ho Sung Choe,Jae Young Heo,Kawn Seob Shim 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.2

In this study, the dietary effects of probiotics with a liquid application system on meat quality and physicochemical characteristics of pigs were evaluated. A total of 80 Landrace×Yorkshire×Duroc (LYD) 3-way crossbred pigs (average age 175±5 d) were assigned to a conventional farm and a probiotics farm equipped with a liquid probiotics application system (40 pigs in each farm). The two treatments were: CON (diet without probiotics) and PRO (diet with probiotics). Dietary probiotics decreased shear force in the longissimus muscle compared to the control group (p<0.05). The treatment diet did not affect backfat thickness, carcass weight, meat color, cooking loss, water holding capacity (WHC), and drip loss. Dietary probiotics significantly reduced ash, salinity, and pH (at 5 and 15 d) (p<0.05). There was no significant effect on thiobarbituric acid reactive substance (TBARS) values. Polyunsaturated fatty acid (PUFA) and omega fatty acids (ω3 and ω6) were significantly (p<0.05) higher in the PRO group, whereas monounsaturated fatty acid (MUFA) was decreased. The free amino acid composition, serine, lysine, histidine, and arginine levels were significantly lower in the PRO than in the control group. The treatment group exhibited higher nucleotide compounds (hypoxanthine, inosine, GMP, IMP) than the controls. Also, levels of ascorbic acid and thiamin were significantly different (p<0.05), while minerals were not significantly different between the groups. In conclusion, feeding of probiotics had effects on shear force, ash, salinity, pH, PUFA, and some amino acids which related to taste and flavor without any negative effects on the pigs’ carcass traits.

Purification and Characterization of Recombinant Bovine Trypsin from Transgenic Rice Cell

Sung-Kun YIM,Yong-Jin KANG,Yun-Ji SHIN,Ju KIM,Moon-Sik YANG,Tae-Ho KWON 한국생물공학회 2013 한국생물공학회 학술대회 Vol.2013 No.10

Self-Transcendence Mediates the Relationship between Early Trauma and Fatal Methods of Suicide Attempts

Yang Jeong Hun,Rhee Sang Jin,Park C. Hyung Keun,Kim Min Ji,Shin Daun,Lee Jae Won,Kim Junghyun,Kim Hyeyoung,Lee Hyun Jeong,Ha Kyooseob,Ahn Yong Min 대한의학회 2021 Journal of Korean medical science Vol.36 No.5

Background: Early trauma is known to be a risk factor of suicide-related behavior. On the other hand, people who attempt suicide using a fatal method are reported to be more likely to complete suicide. In this study, we assumed that early trauma affects an individual's temperament and character and thereby increases the risk of a fatal method of suicide attempts. Methods: We analyzed 92 people with a history of previous suicide attempts. We compared the Temperament and Character Inventory-Revised scores between the groups with and without early trauma, and between the groups with and without a history of suicide attempt using fatal methods through an analysis of covariance with age, sex, and presence of a psychiatric history as covariates. A mediation analysis was conducted of the relationship between early trauma and fatal methods of suicide attempt with self-transcendence as a mediator. Results: Higher self-transcendence was reported in the fatal group (27.71 ± 13.78 vs. 20.97 ± 12.27, P = 0.010) and the early trauma group (28.05 ± 14.30 vs. 19.43 ± 10.73, P = 0.001), respectively. The mediation model showed that self-transcendence mediates the relationship between early trauma and fatal methods of suicide attempt. The 95% confidence intervals for the direct and indirect effect were (−0.559, 1.390) and (0.026, 0.947), respectively. Conclusion: Self-transcendence may mediate the relationship between early trauma and fatal methods of suicide attempt. Self-transcendence may be associated with unhealthy defenses and suicidal behavior for self-punishment and may constitute a marker of higher suicide risk.

Human placental extract suppresses lipopolysaccharide-induced expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells

Yang Sang-eun,Kim Yong-suk,Park Dong-suk 대한침구의학회 2005 대한침구의학회지 Vol.18 No.2

Objectives: 자하거의 소염, 진통효과의 기전을 확인하고, 그 효과를 NSAIDS (aspirin)과 비교하여, 신경계의 퇴행성 질환 및 각정 염증성 질환에의 응용 가능성을 확인하고자 함 Materials & Methods: mouse BV2 microglial cell line을 37℃, 5% CO2, 95% O2로 조절된 세포배양기안에서 10% heat-inactivated fetal bovine serum (FBS)을 공급하면서 Dulbecco's Modified Eagle Medium에서 배양하였다. 자하거약침액의 세포독성은 MTT assay kit (Boehringer Mannheim GmbH, Mannheim, Germany)로 평가하였다. BV2 microglial cells에 lipopolysaccharide (LPS)를 처리하고 1, 5, 10, 50 ㎍/㎖의 자하거약침액 또는 50 ㎍/㎖의 aspirin을 처리한 뒤, RT-PCR로 COX-1, COX-2, iNOS mRNA의 발현을 정량하고 prostaglandin E2 (PGE2)와 nitric oxide (NO)의 농도를 정량하였다. Results: 자하거약침액 1, 5, 10, 50, 100 ㎍/㎖에서는 세포독성이 나타나지 않았다. LPS에 의해 COX-2, iNOS mRNA 발현은 유의하게 (p<0.05) 증가되었으나, COX-1 mRNA의 발현은 증가되지 않았고, COX-1, COX-2, iNOS mRNA의 발현은 자하거약침액의 투여에 의하여 유의하게 (p<0.05) 감소되었으며, 용량의존적인 경향을 나타내었다. PGE2, NO의 발현도 LPS에 의해 유의하게 (p<0.05) 농도가 증가되었다가, 자하거약침액의 투여에 의하여 유의하게 (p<0.05) 농도가 감소되었으며, 용량의존적인 경향을 나타내었다. Conclusions: 자하거약침액은 iNOS와 COX-2의 발현을 억제하여 각각 항염, 진통작용을 나타내며, 관절염 뿐 아니라 Alzheimer's disease, Parkinson's disease 및 ischemic brain injury 등 PGE2, NO가 관련되는 질환들에 임상응용이 가능할 것으로 사려된다.

Improved physicochemical properties and hepatic protection of Maillard reaction products derived from fish protein hydrolysates and ribose

Yang, Sung-Yong,Lee, Sanghoon,Pyo, Min Cheol,Jeon, Hyeonjin,Kim, Yoonsook,Lee, Kwang-Won Elsevier 2017 Food chemistry Vol.221 No.-

<P><B>Abstract</B></P> <P>High amounts of waste products generated from fish-processing need to be disposed of despite their potential nutritional value. A variety of methods, such as enzymatic hydrolysis, have been developed for these byproducts. In the current study, we investigated the physicochemical, biological and antioxidative properties of fish protein hydrolysates (FPH) conjugated with ribose through the Maillard reaction. These glycated conjugates of FPH (GFPH) had more viscous rheological properties than FPH and exhibited higher heat, emulsification and foaming stability. They also protected liver HepG2 cells against <I>t</I>-BHP-induced oxidative stress with enhanced glutathione synthesis <I>in vitro</I>. Furthermore, it was shown that GFPH induced upregulation of phase II enzyme expression, such as that of HO-1 and γ-GCL, via nuclear translocation of Nrf2 and phosphorylation of ERK. Taken together, these results demonstrate the potential of GFPH for use as a functional food ingredient with improved rheological and antioxidative properties.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Maillard reaction products of fish protein hydrolysate improve heat stability. </LI> <LI> Maillard reaction products have improvement of rheological property rather than original protein. </LI> <LI> Maillard reaction products increase Nrf2 translocation and phosphorylation of ERK. </LI> <LI> HO-1 and γ-GCL are up-regulated by Maillard reaction product via Nrf2 activation. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Extremely Low Frequency Magnetic Field is an Environmental Stress Factor by Exerting Oxidative Stress

( Yong Jin Park ),( Won Joo Park ),( Sung Hyuk Yim ),( Seong Jun Yang ),( Yuan Lu Sun ),( Eon Sub Park ),( Ji Hoon Jeong ) 한국응용약물학회 2007 Biomolecules & Therapeutics(구 응용약물학회지) Vol.15 No.1

The previous study reported the biological effect of magnetic held exerted by acting on endocrine and anti-oxidant system. The present study aims to study whether ELF-MF (extremely low frequency magnetic field) affects the physiological endocrine systems such as thyroid and whether ELF-MF affects the defense system against oxidative stress when it alters the function of thyroid. Finally, we correlate the effects of MF on oxidative stress, and adrenal and thyroid with an environmental stress factor. We exposed sham or MF to rats for 5or 25 days. After the exposure, we determined pain sensitivity, level of TSH, T3 and free T4 in plasma. We also assayed in whole brain, lipid peroxidation, the activity of enzymatic anti-oxidant defense including superoxide dismutase (SOD) and glutathione peroxidase (GPx), and non enzymatic defense such as reduced or oxidized glutathione contents. MF induced the hypersensitivity to thermal stimuli with the reduction of latency. T3 and T4 levels were also increased by the exposure of MF. In addition, we observed the rise of MDA level in rat brain by MF although the MF did not change superoxide dismutase and glutathione peroxidase activity. The effect of MF on both reduced and oxidized glutathione results in decrease in reduced or oxidized glutathione in whole brain. In every experiment, there was no significant difference in MF influence between short term (5 days) and long term (25 days) exposure. Taken together, MF exposure affects the thyroid hormonal control in brain. The elevated thyroid hormone acts on brain, leading to hyper-utilization of oxygen. This phenomenon may be correlated with oxidative stress resulting from MF exposure. In conclusion, we suggest that MF exposure may be an environmental stress by exerting oxidative stress.