中國地域 沙漠化와 黃砂現狀에 대한 生態學的 考察

金恩植,김영선,趙學勇 國民大學校 山林科學硏究所 2004 山林科學 Vol.16 No.-

最近 우리나라에서 問題가 되고 있는 黃砂現狀과 그것의 原因이 되고 있는 中國地域 의 沙漠化現狀과 그 硏究史에 대한 生態學的인 考察을 함과 아울러 그에 대한 對應策에 대해서 論議하였다. 沙漠化와 黃砂問題가 發生하는 機作을 提示하고, 그에 대한 對應方案을 論議하였다. Ecological review was carried out to the issues of desertification and Asian Dusts Phenomenon, which are becoming serious recent days in the region of Northeast Asia and discussion was extended to the measures for the issues. The inherent mechanism leading to the desertification and concurrent Asian Dusts Phenomenon and counter measures for the phenomena were suggested.

Parthenolide-Induced Apoptosis, Autophagy and Suppression of Proliferation in HepG2 Cells

Sun, Jing,Zhang, Chan,Bao, Yong-Li,Wu, Yin,Chen, Zhong-Liang,Yu, Chun-Lei,Huang, Yan-Xin,Sun, Ying,Zheng, Li-Hua,Wang, Xue,Li, Yu-Xin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12

Purpose: To investigate the anticancer effects and underlying mechanisms of parthenolide on HepG2 human hepatocellular carcinoma cells. Materials and Methods: Cell viability was assessed by MTT assay and cell apoptosis through DAPI, TUNEL staining and Western blotting. Monodansylcadaverin(MDC) and AO staining were used to detect cell autophagy. Cell proliferation was assessed by Ki67 immunofluorescence staining. Results: Parthenolide induced growth inhibition in HepG2 cells. DAPI and TUNEL staining showed that parthenolide could increase the number of apoptotic nuclei, while reducing the expression of the anti-apoptotic protein Bcl-2 and elevating the expression of related proteins, like p53, Bax, cleaved caspase9 and cleaved caspase3. Parthenolide could induce autophagy in HepG2 cells and inhibited the expression of proliferation-related gene, Ki-67. Conclusions: Parthenolide can exert anti-cancer effects by inducing cell apoptosis, activating autophagy and inhibiting cell proliferation.

Bibliometrics-Based Analysis of the Current State of Equity Incentive Research and Cutting-Edge Trends

Sun, Xue-Bo,Gong, Chi,Liu, Peng 사회혁신기업연구원 2023 혁신기업연구 Vol.8 No.4

Competition among enterprises is becoming more and more intense, equity incentives as one of the main ways of corporate governance, is the most commonly used incentives, equity incentives is the enterprise in order to motivate and retain the core talent and the implementation of long-term incentives for employees. It is of great significance to the development of enterprises. In this paper, we use CiteSpace software to visualise and analyse the domestic research on equity incentives, mainly from the number of articles, authors, keyword clustering and keyword co-occurrence of four aspects of analysis and discussion. It is found that: the number of articles shows an upward trend; there is a lack of close cooperation between core authors; the research hotspots related to equity incentives are mainly the form of incentives, listed companies, corporate governance and corporate performance, etc. The future direction of the research is tilted towards the themes of corporate innovation and investment to explore the impact of the equity incentive approach on corporate innovation and R&D investment.

The Analysis on the Development of South Korean Cruise Tourism of Chinese Tourist Market

Sun, Jing,Jin, Xue,Zheng, Xiaoyi 한중경제문화학회 2015 한중경제문화연구 Vol.4 No.-

As the World Tourism Organization points out that cruise tourism is the best tour product for people to enjoy the diverse experience within the shortest terms. With the constant development of cruise tourism through the years, it has gained the attention of the South Korea. This study analyzes the general information of the cruise ports in South Korea, Chinese cruise tourists to South Korea. To solve problems in the development of cruise tourism of South Korea, this study brings forward to the countermeasures including the developing specialized cruise ports, increasing variety of tour products and strengthening train programs.

Tie1 contributes to the development of ovarian hyperstimulation syndrome under the regulation of EGR1 in granulosa cells

Sun Lihua,Tian Hui,Xue Songguo,Ye Hongjuan,Xue Xue,Wang Rongxiang,Liu Yu,Zhang Caixia,Chen Qiuju,Gao Shaorong 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

The expression of tyrosine kinase with immunoglobulin-like and epidermal growth factor-like domains 1 (Tie1), a transmembrane protein expressed almost exclusively by endothelial cells, has been reported in granulosa cells. However, its significance in ovarian hyperstimulation syndrome (OHSS), which can occur after the injection of gonadotropins in infertile women undergoing controlled ovarian stimulation, is unknown. Here, we report significantly increased Tie1 and vascular endothelial growth factor (VEGF) expression in cultured granulosa cells from OHSS patients, as well as ovaries from rats with experimentally established OHSS, compared to controls, with the levels of both proteins also increasing in granulosa and SVOG cells (a nontumorigenic human granulosa-lutein cell line) treated with an acute dose of human chorionic gonadotropin (hCG). Tie1 silencing abolished the hCG-induced VEGF level in SVOG cells and attenuated the progression of OHSS in rats, as determined by histological analysis. Further studies in SVOG cells revealed that the hCG-induced upregulation of Tie1 expression involved the phosphoinositide 3-kinase/protein kinase B signaling pathway. We also report that early growth response protein 1 (EGR1), whose expression was also upregulated by hCG, bound directly to the Tie1 promoter and activated its transcription. Taken together, our results indicate that Tie1 may be a therapeutic target in cases of moderate-to-severe OHSS. Further studies are needed to address its clinical relevance.

Patterns of Failure and Survival Trends in 3,808 Patients with Stage II Nasopharyngeal Carcinoma Diagnosed from 1990 to 2012: A Large-Scale Retrospective Cohort Study

Xue-Song Sun,Di-Han Liu,Sai-Lan Liu,Qiu-Yan Chen,Shan-Shan Guo,Yue-Feng Wen,Li-Ting Liu,Hao-Jun Xie,Qing-Nan Tang,Yu-Jing Liang,Xiao-Yun Li,Jin-Jie Yan,Ming-Huang Hong,Jun Ma,Lin-Quan Tang,Hai-Qiang M 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4

Purpose The purpose of this study was to investigate the survival trends and patterns of failure in patients with stage II nasopharyngeal carcinoma (NPC) treated with radiotherapy (RT) and chemotherapy over the last 20 years. Materials and Methods Thirty-eight hundred and eight patients diagnosed with stage II NPC between January 1990 and December 2012 were involved in this retrospective cohort study. All patients were treated with RT. According to the main imaging techniques and RT technology, we categorized these patients into four calendar periods: 1990-1996, 1997-2002, 2003-2007, and 2008-2012. Overall survival (OS), progression-free survival (PFS), locoregional relapse-free survival (LRFS), and distant metastasis–free survival (DMFS) were served as the clinical outcome. Results After a median follow-up period of 84.7 months, we observed increasing trends in survival and disease control. The 3- and 5-year OS rates increased from 87.1% and 78.7% in the first calendar period to 97.4% and 94.5% in the last calendar period, respectively (p < 0.001). Additionally, significant increasing trends could be seen in the PFS and LRFS during the four calendar periods. In the subgroup analysis, the LRFS in patients older than 50 years at diagnosis showed greater improvement than younger patients. However, the rate of distant metastasis was stable and relatively low, as the 5-year DMFS ranged from 90.5% to 94.7% among the four calendar periods. Conclusion The survival rates in patients with stage II NPC showed increasing trends from 1990 to 2012. The advance of RT provided excellent locoregional control and enhanced OS.

Subdivision of Nasopharyngeal Carcinoma Patients with Bone-Only Metastasis at Diagnosis for Prediction of Survival and Treatment Guidance

Xue-Song Sun,Yu-Jing Liang,Sai-Lan Liu,Qiu-Yan Chen,Shan-Shan Guo,Yue-Feng Wen,Li-Ting Liu,Hao-Jun Xie,Qing-Nan Tang,Xiao-Yun Li,Jin-Jie Yan,Lin-Quan Tang,Hai-Qiang Mai 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4

Purpose The purpose of this study was to subdivide M1 stage nasopharyngeal carcinoma (NPC) patients with bone-only metastases for prognosis prediction while identifying the treatment effect of locoregional radiotherapy (LRRT) and metastasis radiotherapy (MRT) among patients with different risk. Materials and Methods From November 2006 to October 2016, a total of 226 patients with bone-only metastasic NPC were retrospectively enrolled. All patients developed distant lesions before receiving treatment. All potential prognostic factors were considered and the correlation of the M1 subdivisions with overall survival (OS) was determined by Cox regression hazards model. Kaplan-Meier curves were used to appraise survival condition and log-rank testing was used to compare the differences. Results The median follow-up time was 33.9 months (range, 3 to 126 months). According to multivariate Cox proportional hazard analysis, the number of metastatic lesions and Epstein-Barr virus (EBV) DNA status after palliative chemotherapy (PCT) were independent prognostic factors for OS. Thus, we subdivided patients into three risk groups according to these two factors. Systemic chemotherapy combined with LRRT may benefit patients in low- and intermediate-risk groups but not in the high-risk group. Further aggressive MRT based on systemic chemotherapy showed no survival benefit in any risk group. Conclusion The stratification of NPC patients with bone-only metastasis based on EBV DNA after PCT and the number of metastatic lesions provided promising prognostic value and could aid clinicians in person-specific treatment.

In vitro Plantlet Regeneration from Stem Segments and Germinated Seedlings of Cathaya argyrophylla, an Endangered Species

Xue Sun,Lu-Min Vaario,Shu-Tang Xing,Saneyuki Kawabata,Yu-Hua Li 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

Hot Forging Process Design Optimization Based on Approximate Model and FEM Simulation

Chen, Xue Wen,Jung, Dong Won,Sun, Ai Xue Trans Tech Publications, Ltd. 2008 Materials science forum Vol.575 No.-

<P>Technology and die design are very important in the development of forging products due to its great influence on the quality, cost and manufacturing efficiency of the final products as well as the life of the forging die. In the environment of the severe competition, how to improve the quality of forging technology and die design, to reduce the product cost and ultimately to enhance competitiveness of the forging factory are the problems that forging technology and die designer have to solve. In order to improve the quality of forging technology and die design, a design optimization method based on approximate model (response surface model) and FEM technique for hot forging process is proposed in this paper. During design optimization process, finite element analysis is incorporated to calculate the objective function and check the design alternatives. Design of experiment (DOE) method is used to collect sample points and calculate the polynomial coefficients of response surface model, and approximate model is used to calculate the optimum search direction. Finally, a case study is conducted for a gear workpiece hot forging process. The objective function is the degree of uniformity of equivalent-strain, which can be defined as mean square deviation of the equivalent-strain in each element and the average equivalent-strain of all elements, and the design parameters are the initial H0/D0 ratio of billet and the key dimensions of the die. Then the design optimization mathematical model is established. The result shows that the objective function value is dropped from 0.7914 and converges at 0.4843 within 17 iterations, the optimal design parameters are obtained.</P>

Disturbance Rejection of Superheated Steam Temperature in a Utility Boiler

Li Sun,Donghai Li,Yong Sun,Yali Xue,Kwang Y. Lee 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10

This paper derived a model for the superheated steam temperature based on the open-loop step response. A cascaded control structure based on disturbance observer (DOB) is proposed to accommodate the control difficulties. The simulation results show the great performance improvement compared with the conventional cascaded control structure. This paper is a preliminary research to the cascaded DOB control structure. Much improvement, theoretic analysis and experimental demonstration will be carried out in the future.