金久永의 『病因論』에 나타난 의학사상 연구

김정원(Chong Won Kim),김남일(Nam il Kim),차웅석(Wung Seok Cha) 한국의사학회 2017 한국의사학회지 Vol.30 No.1

This paper is a study on the life and clinical reasoning of Kim Goo Young (1958-2014). Offering a new perspective through his interpretation of Donguibogam (東醫寶鑑), Kim introduced his unique theory of Korean medicine, ‘The Theory of Byeongin (病因論)’. Kim recognized the confusing situation of communication between people studying Korean medicine and tried to make a new standard based on the principle that many people can share. ‘The Theory of Byeongin offers a newly constituted 󰡔Donguibogam󰡕 focusing on ‘Byeongin’ (病因, pathologic origin) which can be translated as the cause of a disease. In so doing Kim recognized ‘Byeongin as the most important factor in ‘Byeonjeung’ (辨證, classifying the origin), or the classification method of symptoms. In addition, Kim recognized how ‘Byeongin was considered to be a diseased lifestyle, and tried interpreting. The patient’s lifestyle to treat diseases. As a result, ‘The Theory of Byeongin’ is a theory consisting of an intuitive structure, reducing notable elements like Yin Yang Five Movement theory. The theory s significant characteristic is its easy application in clinical settings due the established core principles which are based on Kim’s insight and clinical experience. This study contributes to the understanding of the theoretical and clinical development of Korean medicine through deeper studies on ‘The Theory of Byeongin and Kim s medical theory.

Analysis of the Motion of a Harmonic Oscillator Coupled to Faraday's Law

KIM*, Se-Hun,KO, Tae-Eon,LEE, Se-Hyun,KIM, Kwang-Sun,OH, Seung-Won,KIM, Hyun-Seok Korean Physical Society 2018 새물리 Vol.68 No.1

양궁 선수의 마음챙김 능력 향상을 위한 심리훈련 프로그램 적용

김진호(Kim, Jin-Ho),오원석(Oh, Won-Seok) 한국사회체육학회 2017 한국사회체육학회지 Vol.0 No.67

The purpose of this study is to investigate the effects of mindfulness training with psychological techniques in a professional archery team in South Korea. First of all, it is conducted to find the changes in mindfulness through the KIMS during the mindfulness training, and to analyze the changes in both mindfulness and psychological technique factors. After ten times of meditation (1h-1h30m/1d), ACT and MAC based on the mindfulness training program, there were significant positive influences of psychological factors such as techniques, acceptance, concentration behavior and attention behavior on an intervention group compared to a control group, resulting in KIMS. Although there were no significant differences in confidence and teamwork in the intervention group after the psychological techniques, there were positive effects on willpower, goal setting , concentration, anxiety control and imagery statistically in the intervention group. In conclusion, mindfulness training has positive effects on the mindfulness in Korean archers. This training also has a positive influence on psychological technique factors such as attention, imagery, concentration and anxiety control. According to previous literatures, it is proved that there were positive effects on the psychological technique factors with the changes in mindfulness. Therefore, it is required to develop tools which can measure the mindfulness and to apply the correlation of mindfulness and psychological techniques to the field.

Discovery of urinary metabolomic biomarkers for early detection of acute kidney injury

Won, A Jin,Kim, Siwon,Kim, Yoon Gyoon,Kim, Kyu-Bong,Choi, Wahn Soo,Kacew, Sam,Kim, Kyeong Seok,Jung, Jee H.,Lee, Byung Mu,Kim, Suhkmann,Kim, Hyung Sik The Royal Society of Chemistry 2016 Molecular bioSystems Vol.12 No.1

<P>The discovery of new biomarkers for early detection of drug-induced acute kidney injury (AKI) is clinically important. In this study, sensitive metabolomic biomarkers identified in the urine of rats were used to detect cisplatin-induced AKI. Cisplatin (10 mg kg(-1), i.p.) was administered to Sprague-Dawley rats, which were subsequently euthanized after 1, 3 or 5 days. In cisplatin-treated rats, mild histopathological alterations were noted at day 1, and these changes were severe at days 3 and 5. Blood urea nitrogen (BUN) and serum creatinine (SCr) levels were significantly increased at days 3 and 5. The levels of new urinary protein-based biomarkers, including kidney injury molecule-1 (KIM-1), glutathione S-transferase-alpha (GST-alpha), tissue inhibitor of metalloproteinase-1 (TIMP-1), vascular endothelial growth factor (VEGF), calbindin, clusterin, neutrophil, neutrophil gelatinase-associated lipocalin (NGAL), and osteopontin, were significantly elevated at days 3 and 5. Among urinary metabolites, trigonelline and 3-indoxylsulfate (3-IS) levels were significantly decreased in urine collected from cisplatin-treated rats prior to histological kidney damage. However, carbon tetrachloride (CCl4), a hepatotoxicant, did not affect these urinary biomarkers. Trigonelline is closely associated with GSH depletion and results in insufficient antioxidant capacity against cisplatin-induced AKI. The predominant cisplatin-induced AKI marker appeared to be reduced in urinary 3-IS levels. Because 3-IS is predominantly excreted via active secretion in proximal tubules, a decrease is indicative of tubular damage. Further, urinary excretion of 3-IS levels was markedly reduced in patients with AKI compared to normal subjects. The area under the curve receiver operating characteristics (AUC-ROC) for 3-IS was higher than for SCr, BUN, lactate dehydrogenase (LDH), total protein, and glucose. Therefore, low urinary or high serum 3-IS levels may be more useful for early detection of AKI than conventional biomarkers.</P>

동북아 피더네트워크의 Win-win전략에 관한 연구

장우준(Woo-jun jang),전찬용(Chan-Yong jeon),김태원(Tae-Won Kim),곽규석(Kyu-Seok Kwak),남기찬(Ki-Chan Nam) 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.3 No.1

최근 중국은 양산항을 개장하여 선사 유치를 위한 다양한 혜택을 제공하고, 일본은 "수퍼중추항만 육성계획“을 세워 항만의 효율성을 바탕으로 비용을 낮추려는 노력을 하고 있다. 또한 선박의 대형화에 의한 중심항만(Hub Port) 위주의 기항과 북중국의 대량 물량 발생지역에 대한 직기항 경향으로 동북아 항만간의 경쟁이 더욱더 치열해 지고 있으며 동북아 역내 피더네트워크 강화의 필요성이 제기되고 있다. 따라서, 본 연구에서는 유럽 피더네트워크 전략 사례를 바탕으로 동북아 피더시장 현황을 파악하고 동북아 피더네트워크 구조를 분석함으로써 동북아 역내 항만 및 선사간의 과당경쟁을 지양하고 서로 Win-Win할 수 있는 터미널의 전략적 활용, 선사간 제휴 확대, 항만간 협력 강화를 위한 구체적인 전략을 제시하였다. Recently, China opened Yangshan port and provides a variety of benefits for shipping companies. Japan plans to reduce logistics costs and improve efficiency through the established "super major ports" project. According to the "hub and spokes" system, the number of direct calls toward North-Chinese ports are increasing. This changing environment has negative effects on the amount of transshipment cargos in Korean ports. In order to make a hub port of a domestic port, it is necessary to develop northeast Asian feeder networks. Therefore, this paper analyzes the structure of northeast Asian feeder networks through the case study of European feeder networks strategy. Finally, we suggests the plans to reinforce feeder networks, which are strategic terminal operation, strategic alliances between shipping companies and port co-operation, for win-win strategy in the competitive northeast Asian market.

통풍형 방음벽 개발 및 적용에 관한 연구

윤제원(Je-Won Yoon),김영찬(Young-Chan Kim),김금모(Keum-Mo Kim),장강석(Kang-Seok Jang),구본성(Bon-Sung Ku),엄주용(Joo-Yong Eom) 한국소음진동공학회 2011 한국소음진동공학회 학술대회논문집 Vol.2011 No.10

The purpose of this study is to develop an air-passing soundproofing panel with more improved structure to reduce the CO2 emission and installation cost. To reduce the emission of CO2 ; it is suggested to choose low CO2 emission material relative to the aluminum and to reduce the materials by developing a specially designed air-passing soundproofing panel structure. First of all, we performed the flow analysis to predict the wind pressure according to the open angle of the air-passing soundproofing panel and the noise level analysis at the receiver point. To verify the simulation, a prototype of the soundproofing panel was made. The flow test in the wind tunnel and load test were performed. The economic evaluation for the installation of the air-passing soundproofing panel was performed and specifications of the installation was prepared. As the results of this research, it was verified that the wind load was reduced about 40% to that of the conventional one at 25m/s wind speed in the wind tunnel test. By applying the 4m span soundproofing wall with air-passing soundproofing panel and under the cost of 250 thousand won/m2 instead of the conventional 2m span panel, the installation cost will always be lowered than the conventional one in the combination of (60:40~50:50) conventional to air-passing soundproofing panel from the economic evaluation. The 20% reduction of CO2 was found by changing the 50% of aluminum soundproof panel to air-passing soundproofing panel.

Original Articles : Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients

( Jae Young Jang ),( Soung Won Jeong ),( Sung Ran Cheon1 ),( Sae Hwan Lee1 ),( Sang Gyune Kim ),( Young Koog Cheon ),( Young Seok Kim1 ),( Young Deok Cho1 ),( Hong Soo Kim ),( So Young Jin ),( Yun Soo 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3

Background/Aims: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver disease. Methods: Seventy-one hepatitis B virus surface-antigen (HBsAg)-negative patients were divided according to their HBV serological status into groups A (anti-HBc positive, anti-HBs negative; n=18), B (anti-HBc positive, anti-HBs positive; n=34), and C (anti-HBc negative, anti-HBs positive/negative; n=19), and by anti-HCV positivity (anti-HCV positive; n=32 vs. anti-HCV negative; n=39). Liver biopsy samples were taken, and HBV DNA was quantified by real-time PCR. Results: Intrahepatic HBV DNA was detected in 32.4% (23/71) of the entire cohort, and HBV DNA levels were invariably low in the different groups. Occult HBV infection was detected more frequently in the anti-HBc-positive patients. Intrahepatic HBV DNA was detected in 28.1% (9/32) of the anti-HCV-positive and 35.9% (14/39) of the anti-HCV-negative subjects. The HCV genotype did not affect the detection rate of intrahepatic HBV DNA. In anti-HCV-positive cases, occult HBV infection did not affect liver disease severity. Conclusions: Low levels of intrahepatic HBV DNA were detected frequently in both HBsAg-negative and anti-HCV-positive cases. However, the frequency of occult HBV infection was not affected by the presence of hepatitis C, and occult HBV infection did not have a significant effect on the disease severity of hepatitis C. (Korean J Hepatol 2011;17:206-212)

비만환자의 전기지방분해침 시술 후 허리둘레 감소에 대한 임상적 고찰

김정환 ( Jeong Hwan Kim ),고연석 ( Youn Seok Ko ),이정한 ( Jeong Han Lee ),원재균 ( Jea Kyun Won ),신병철 ( Byung Cheul Shin ),권영달 ( Young Dal Kwon ),송용선 ( Yung Sun Song ) 한방재활의학과학회 2005 한방재활의학과학회지 Vol.15 No.3

Objectives : To see if there were any differences in waist circumference reduction when certain variable such as age, sex, BFR(BFR; Body Fat Rate), PIBW(PIBW; Percent Ideal Body Weight), WHR(WHR; Waist Hip Ratio) and BMI(BMI; Body Mass Index) were given. Methods : Among outpatients who admitted to department of Oriental Rehabilitation Medicine, Jeon-Ju Oriental Medicine Hospital, Won-kwang University from August 2003 to september 2004, 89 obese patients were chosen and electroacupunture was practiced to these groups in order to treat abdominal obesity and waist circumference reduction. Results : There were no significant correlation between sex, age and waist circumference reduction. Compared to groups who had shown lower BMI, higher BMI groups have shown greater change in waist circumference reduction. As BFR increase waist circumference reduction tended to increase as well. Conclusions : From the above results, higher BMI groups had shown greater change in waist circumference reduction compared to lower BMI groups.

한방 닭죽 개발 및 최적 배합비율 확립

김경연 ( Kyung Yeon Kim ),백무열 ( Moo Yeol Baik ),박천석 ( Cheon Seok Park ),최성원 ( Sung Won Choi ),김창남 ( Chang Nam Kim ),김병용 ( Byung Yong Kim ) 한국식품영양학회 2013 韓國食品營養學會誌 Vol.26 No.1

죽의 기능성 향상을 위하여 2:1:1:1의 배합으로 혼합한 한약재료(가시오가피, 숙지황, 산약, 백복령)와 닭가슴살 등의 재료를 사용해 한방 영양죽을 제조하였다. 한방 닭죽의 DPPH radical 소거능, SOD 유사활성, 맛의 선호도, cost는 수학적인 canonical model과 trace plot을 이용하여 분석한 결과, SOD 유사활성 이외에는 각 성분들이 독립적으로 작용하여 상호작용이 없는 선형 모델을 보여주었다. DPPH radical 소거능, SOD 유사활성, 맛의 선호도를 최대로, cost를 최소로 목적 범위를 설정하고, 각각의 canonical 계수를 이용하여 수적 최적화를 통하여 최적 배합비를 구한 결과, 한약 혼합물 101g, 닭가슴살 38.66g, 찹쌀 비율 41.34g의 최적 배합비를 구하였으며, 이 배합비에 따른 맛의 선호도는 6.39, DPPH radical 소거능은 17.25㎎VCE/ℓ, SOD 유사활성은 2.25%, cost는 1,382.39 won으로 나타났으며, 여러 결과들 사이에 최적화된 한 값에 수렴하는 desirability는 0.714로 나타났다. 이는 한약혼합물이 많을수록 기능성 면에서는 높게 나타나지만 맛의 선호도면에서는 낮게 나타냈고, 닭가슴살의 경우에도 그 함량이 많을수록 맛의 선호도는 올라갔지만 그에 반해 cost가 높게 올라간 것을 반영한 결과로 사료된다. The objectives of this study were to develop porridge with medicinal herbs and chicken breast meat and to find out the optimum mixing ratio. Several herb extracts such as Acanthopanacis senticosus, Rehmannia glutinosa, Disocorea japonica, and Poria cocos Wolf were used in the ratio of 2, 1, 1, and 1, respectively. The optimum processing condition for herbal chicken porridge was determined by a design expert program. Seventeen experimental points were selected, and herb extracts (82∼101g), chicken breast meat (30∼50g), and glutinous rice (40∼60g) were chosen as the independent variables. The measured responses were preference of taste, DPPH radical scavenging, SOD-like activity, and cost. The optimum formulation of herbal chicken porridge using the numerical analysis was set at herbal extracts (101g), chicken breast meat (38.66g), and glutinous rice (41.34g) with a 0.714 desirability value. DPPH radical scavenging effect, preference of taste and the cost showed a linear model, whereas SOD-like activity showed a quadratic model indicating a higher interaction among the mixture. As a result of proximate composition of optimized herbal chicken porridge, the contents of moisture, carbohydrate, crude protein, crude lipid, and ash contents were 76.4, 9.0, 1.4, 0.5, and 1.6%, the calories of the porridge was 46.1kcal/100g.

건조방법에 따른 하수슬러지 건조속도 비교 및 경제성 평가

박성훈 ( Seong-hun Park ),김한석 ( Han-seok Kim ),이승원 ( Seung-won Lee ) 한국환경기술학회 2021 한국환경기술학회지 Vol.22 No.3

In this study investigated the effect of the chemical injection ratio on the drying rate of sewage sludge. Then the economic efficiency was evaluated by comparing the results of the NIR(near infrared ray) and microwave drying rate test. The near infrared ray device showed drying speed of 31.9 %, 28.1 %, and 27.1 % at polymer dose ratio of 8 %, 10 %, and 12 %, respectively. Compared to 8 % polymer dose ratio, polymer dose ratio of 10 % and 12 % showed differences of 8.0 % and 13.6 % respectively, suggesting that drying efficiency decreased as polymer dose ratio increased. The microwave device showed drying speed of 26.2 %, 24.3 %, 21.3 % at polymer dose ratio of 8 %, 10 %, and 12 %, respectively. Compared to 8 % polymer dose ratio, polymer dose ratio of 10 % and 12 % showed differences of 5.2 % and 13.4 % respectively, suggesting that drying efficiency decreased as polymer dose ratio increased. Drying evaluation estimated the treatment cost of near infrared ray device at optimal dose ratio(6 %) was 35,591 won/ton while that of actual dose ratio(8 %) was 38,928 won/ton. Drying evaluation estimated treatment cost of microwave device at optimal polymer dose ratio(6 %) and at 8 % to be 16,683 won/ton and 18,352 won/ton, respectively.