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Song, Su-Min,Shin, Jong-Won,de Guzman, Jefferson V.,Kim, Jin,Yu, Hak-Sun,Jha, Bijay Kumar,Kong, Hyun-Hee,Hong, Yeonchul,Chung, Dong-Il Elsevier 2010 Experimental parasitology Vol.125 No.2
<P><B>Abstract</B></P><P><I>Paragonimus westermani</I> is a trematode parasite that causes inflammatory lung disease as well as systemic infections in carnivorous mammals. The interaction of the parasite with host cells and paired worms is initiated by adhesion and plays an important role in parasite proliferation and differentiation. In this study, we isolated a cDNA encoding a <I>P. westermani</I> fasciclin I domain-containing protein (Pwfas-I). The fasiclin-I domain is suggested to be involved in cell adhesion, migration, and differentiation. Immunohistochemical analysis of <I>P. westermani</I> adult worms with polyclonal anti-Pwfas-I serum revealed immunoreactivity in the egg shells and the cells lining the sub-tegumental layer of adult worm throughout the contact regions of the cyst wall and paired worms. Using cell adhesion and spreading assays, we showed that Pwfas-I supports cell adhesion and spreading. Furthermore, we determined that the ανβ5 integrin was a functional receptor for the Pwfas-I. Taken together, these results suggest that Pwfas-I may be functional for the modulation of cell adhesion via binding with ανβ5 integrin in the extracellular matrix of <I>Paragonimus</I>.</P>
Song, Eui-Geun,Lee, Hwa-Su,Park, Hee-Bok,Woo, Dong-Gul,Park, Tae-Jin,Chun, Su-Won,Sim, Seung-Woo,Cha, Hyoun-Gi,Lim, Anya,Choi, Tae-Young Institute of Forest Science 2018 Journal of Forest Science Vol.34 No.2
The purpose of this study is to compare the bird crossing of roads by type (Expressway 1, railroad-provincial road and Highway 4) and the crossing of roads according to the size of birds. The greatest number of avian species and individuals crossing road per 10 minutes were found on railroad-provincial road ($8.96{\pm}1.92$ and $29.33{\pm}11.94$, respectively), while the lowest number of avian species and individuals were found on Expressway 1 ($2.96{\pm}1.04$ and $6.13{\pm}2.89$, respectively), which has the widest width. In addition, the number of small-sized bird (<20 cm) crossing the Expressway 1, railroad-provincial road, and Highway 4 was lower than that of the medium-sized bird (${\geq}20cm$). Current wildlife crossing structures have been focused on mammals, amphibians and reptiles, but future structures should also consider birds.
( Hee-jin Park ),( Jungsik Song ),( Yong-beom Park ),( Soo-kon Lee ),( Sang-won Lee ) 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.6
Background/Aims: Red blood cell distribution width (RDW) is a value representing the heterogeneity in the size of red blood cell, and it is usually used in distinguishing types of anaemia. Recently, it was reported that it could reflect the burden of inflammation in diverse diseases and their prognosis. Hence, in this study, we investigated whether RDW may contribute to discriminating adult onset Still’s disease (AOSD) from sepsis in serious febrile patients within 24 hours after hospitalization. Methods: We reviewed the medical records and enrolled 21 AOSD patients, 27 sepsis patients and 30 matched healthy controls. We collected at least two laboratory results of variables including RDW within 24 hours after hospitalization, and we calculated their mean values. Results: Sepsis patients showed the significantly increased median white blood cell count, compared to AOSD patients (14,390.0/mm3 vs. 12,390.0/mm3, p = 0.010). The median RDW in sepsis patients was higher than that in AOSD patients (15.0% vs. 13.3%, p = 0.001), and furthermore, the median RDW in both patient-groups was significantly higher than that in healthy controls. In contrast, the median ferritin level in sepsis patients was lower than that in AOSD patients (544.0 mg/dL vs. 3,756.6 mg/dL, p = 0.001). In multivariate analysis, RDW ≥ 14.8% (odds ratio, 17.549) and ferritin < 2,251.0 mg/dL (odds ratio, 32.414) independently suggested sepsis more than AOSD in patients initially presenting with fever requiring hospitalization. Conclusions: RDW might be a rapid and helpful marker for a differential diagnosis between AOSD from sepsis at an early phase.
Song, Young Hyun,Park, Sang-Yul,Yoo, Jin Sun,Park, Won Kyu,Kim, Hyo Sun,Choi, Seung Hee,Kwon, Seok Bin,Kang, Bong Kyun,Kim, Jae Pil,Jung, Hyun Suk,Yoon, Dae Ho,Yang, Woo Seok,Seo, Young-Soo Elsevier 2018 Chemical Engineering Journal Vol.352 No.-
<P><B>Abstract</B></P> <P>Fully inorganic lead halide perovskite materials have attracted tremendous attention because of their practical applications in optoelectronic devices, such as light emitting diodes. In this work, we report the first development of highly efficient, stable and green-emitting CsPbBr<SUB>3</SUB> perovskite NCs with a PE microcapsule. The CsPbBr<SUB>3</SUB> perovskite NCs were perfectly incorporated inside the PE microcapsule with a multi-lamellar structure, which shows better luminescence characteristics such as a high PLQY and thermal stability Furthermore, our results revealed the high luminous performance with a white conversion efficacy of 62.4 lm W<SUP>−1</SUP>, EQE of 31.8%, CRI of 37.01, and CCT of 6028 K on blue emitting InGaN LED chip. We suggest that our material will be one of the next generation candidate luminescence materials for application in optoelectronic devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We successfully synthesized the efficient and stable green-emitting CsPbBr<SUB>3</SUB> perovskite nanocrystals. </LI> <LI> CsPbBr<SUB>3</SUB> perovskite of using the multi-lamellar microcapsule enhances the PLQY to 40%. </LI> <LI> The encapsulated perovskite NC composite material represents a next generation candidate luminescence material. </LI> </UL> </P>
Benzo(a)pyrene has effects on the repression of melanogenesis in B16F10 mouse melanoma cells
( Song Hee Han ),( Byung Gon Choi ),( Min Jung Kim ),( Hae Jeong Youn ),( Soo Young Kim ),( Nam Kyung Roh ),( Ho Jung Jung ),( Yu Ri Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2
Background: Benzo(a)pyrene (BaP) is one of the various toxic substances in polluted air. In previous studies, it was reported that BaP accumulates in melanin-containing tissues. However, it remains unclear whether BaP regulates melanogenesis in melanocytes Objectives: We examine the effects of BaP on the melanin synthesis pathway, as well as its effects on the repression of melanogenesis in B16F10 mouse melanoma cell Methods: The melanin content was determined by optical density at 415 nm and normalized to the amount of total protein. We used Western blot with antibodies against MITF, tyrosinase, Tyrp1, Tyrp2 to detect specific proteins. In vitro tyrosinase activity was determined using mushroom tyrosinase. Quantitative real-time PCR was used to determine relative target mRNA expression Results: The mRNA expression of Typ and Tyrp1 were significantly inhibitied in the presence of BaP compared to control メ-MSH treated B16F10 cells. BaP repressed Mitf mRNA and protein expression in メ-MSH treated B16F10 cells. BaP significantly decreased melanin synthesis by Microphthalmia-associated transcription factor-mediated regulation of tyrosinase and tyrosinase-related protein 1 expression in B16F10 mouse melanoma Conclusion: We hypothesize that BaP interrupts the UV protection mechanism by repressing melanin synthesis in the skin, because メ-MSH-induced melanogenesis, the major protection mechanism in UV-exposed skin, is significantly decreased by BaP in B16F10 cells