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Wenyu Liu,Haishan Zhou,Muxin Zhang,Ying Shang,Yudan Liu 대한전자공학회 2022 IEIE Transactions on Smart Processing & Computing Vol.11 No.6
This paper presents a remote identification method for smart-meter operation errors based on a wireless sensor network (WSN) in a smart city to reduce the bad operation of smart meters. In the WSN, ZigBee communication technology was used to collect data from smart meters to enhance the reliability of information. The LEACH protocol can effectively extend the network life cycle and was selected as a communication protocol for WSNs to collect operation data from intelligent meters. Based on the operation data of a smart meter collected by a WSN, a remote identification model of operation error of a smart meter was established. The limited memory least square algorithm was adopted to construct the remote identification model of operation error for a smart meter to realize the remote identification of a smart-meter error in a smart city. The proposed method can use a WSN to collect operation data from a smart meter and remotely identify the mean absolute percentage error (MAPE) and root mean square error (RMSE) of a smart meter’s operation error, which were less than 1%.
High efficiency top-emitting white organic light-emitting devices with a (metal/organic)_2 cathode
Wenyu Ji,Letian Zhang,Mo Liu,Jing Wang,Guoqiang Liu,Wenfa Xie,Hanzhuang Zhang 한국물리학회 2011 Current Applied Physics Vol.11 No.6
White top-emitting organic light-emitting devices (TEOLEDs) were fabricated on a glass substrate with metal/organic multilayer of (Ag/Alq_3)_2 (Alq3 is tris-(8-hydroxyquinoline) aluminum) as cathode. White TEOLEDs with high efficiencywere obtained due to the microcavity effects.Andthe (Ag/Alq_3)_2 cathode,which adjusted the optical characteristics of the devices, played an important role. In addition, Alq_3―Ag―Alq_3multilayer could work as a buffer layer, which would simplify the process of encapsulation for devices.We also calculated the electroluminescence spectrum of devices encapsulated with Al_2O_3 (150 nm) and Al_2O_3(75 nm)/ZrO_2(75 nm). And the results indicated that the CIE coordinates is almost the same between with and without encapsulating.
Chunna Liu,Huijiao Lin,Liu Jiawei,Yao Wang,Chunmei Wang,Jinghui Sun,Chunyan Yu,Ying Dong,Wenyue Zhuang,Shu Jing,JianGuang Chen,He Li 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.8
Free radical accumulation in the body will cause oxidative stress damages including the renal damage. Schisandrae Sphenantherae Fructus (Schisandra), a traditional Chinese herbal medicine, has been used throughout the world. Anwulignan, a monomer extracted from Schisandra, has been shown in our previous studies to possess antioxidant and protective effects on the liver, brain and spleen damages in the aging mice. However, its effect on the renal damage caused by aging is not clear. This study showed that anwulignan could significantly increase the kidney index, the creatinine clearance, the activities of superoxide dismutase, catalase and glutathione peroxidase; reduce the urinary protein concentration, the serum urea nitrogen and creatinine content, the content of malondialdehyde and 8-hydroxylated deoxyguanosine in the renal tissue; and improve the renal tissue damage. Moreover, anwulignan increased the production of Nrf2, HO-1 and NQO1 proteins and decreased the production level of Keap1 protein in the renal tissue in the D-galactose induced aging mice. These results suggest that anwulignan significantly alleviates the renal damage by its antioxidant effect through regulating the production of Nrf2/ARE pathway-related proteins in the renal tissue in the D-galactose induced aging mice.
Li Shuang,Guo Dongyang,Sun Qiang,Zhang Lu,Cui Yun,Liu Min,Ma Xixi,Liu Yiman,Cui Wenyu,Sun Leimin,Teng Lisong,Wang Liangjing,Lin Aifu,Liu Wei,Zhuo Wei,Zhou Tianhua 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Liver metastasis is a major cause of death in gastric cancer patients, but the underlying mechanisms are poorly understood. Through a combination of in vivo screening and transcriptome profiling followed by quantitative RT-PCR and tissue array analyses, we found that mitogen-activated protein kinase 4 (MAPK4) downregulation in gastric cancer tissues from patients is significantly associated with liver metastasis and poor prognosis. The knockdown of MAPK4 in gastric cancer cells promotes liver metastasis in orthotopic mouse models. MAPK4 depletion in gastric cancer cells induces the secretion of macrophage migration inhibitory factor (MIF) to polarize tumor-associated macrophages (TAMs) in orthotopic xenograft tumors. Moreover, TAMs activate epithelial–mesenchymal transition of gastric cancer cells to suppress MAPK4 expression, which further increases MIF secretion to polarize TAMs. Taken together, our results suggest a previously undescribed positive feedback loop between cancer cells and macrophages mediated by MAPK4 silencing that facilitates gastric cancer liver metastasis.
( Wenyu Li ),( Fan Yin ),( Zixuan Bu ),( Yuying Liu ),( Yongqing Zhang ),( Xiabing Chen ),( Shaowen Li ),( Lu Li ),( Rui Zhou ),( Qi Huang ) 한국미생물 · 생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.3
Live bacterial vector vaccines are one of the most promising vaccine types and have the advantages of low cost, flexibility, and good safety. Meanwhile, protein secretion systems have been reported as useful tools to facilitate the release of heterologous antigen proteins from bacterial vectors. The twin-arginine translocation (Tat) system is an important protein export system that transports fully folded proteins in a signal peptide-dependent manner. In this study, we constructed a live vector vaccine using an engineered commensal Escherichia coli strain in which amiA and amiC genes were deleted, resulting in a leaky outer membrane that allows the release of periplasmic proteins to the extracellular environment. The protective antigen proteins SLY, enolase, and Sbp against Streptococcus suis were targeted to the Tat pathway by fusing a Tat signal peptide. Our results showed that by exploiting the Tat pathway and the outer membrane-defective E. coli strain, the antigen proteins were successfully secreted. The strains secreting the antigen proteins were used to vaccinate mice. After S. suis challenge, the vaccinated group showed significantly higher survival and milder clinical symptoms compared with the vector group. Further analysis showed that the mice in the vaccinated group had lower burdens of bacteria load and slighter pathological changes. Our study reports a novel live bacterial vector vaccine that uses the Tat system and provides a new alternative for developing S. suis vaccine.
POLYNOMIAL COMPLEXITY OF PRIMAL-DUAL INTERIOR-POINT METHODS FOR CONVEX QUADRATIC PROGRAMMING
Liu, Zhongyi,Sun, Wenyu,De Sampaio, Raimundo J.B. The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.3
Recently, Peng et al. proposed a primal-dual interior-point method with new search direction and self-regular proximity for LP. This new large-update method has the currently best theoretical performance with polynomial complexity of O($n^{\frac{q+1}{2q}}\;{\log}\;{\frac{n}{\varepsilon}}$). In this paper we use this search direction to propose a primal-dual interior-point method for convex quadratic programming (QP). We overcome the difficulty in analyzing the complexity of the primal-dual interior-point methods for convex quadratic programming, and obtain the same polynomial complexity of O($n^{\frac{q+1}{2q}}\;{\log}\;{\frac{n}{\varepsilon}}$) for convex quadratic programming.
750 GeV diphoton resonance in a vector-like extension of Hill model at a 100 TeV hadron collider
Liu, Ning,Wang, Wenyu,Zhang, Mengchao,Zheng, Rui World Scientific 2016 International Journal of Modern Physics A Vol.31 No.25
<P> In this paper, we study the recent 750 GeV diphoton excess in the Hill model with vector-like fermions. The singlet-like Hill boson is chosen as the 750 GeV diphoton resonance. Such a scalar is mainly produced by gluon fusion via vector-like top and bottom quark loops and decays to diphoton via the vector-like quark and lepton loops. Under the current experimental and theoretical constraints, we find that the mixing angle of the singlet and doublet Higgs bosons lies within [Formula: see text] and the 750 GeV diphoton cross-section can be maximally enhanced to about 6 fb at 13 TeV LHC. Moreover, we find that the Hill boson pair production in [Formula: see text] channel can be probed at [Formula: see text] significance if [Formula: see text] and [Formula: see text] at a 100 TeV collider with 3000 fb[Formula: see text] luminosity. </P>
( Hongtao Liu ),( Seng Zhu ),( Yingying Sun ),( Na Li ),( Jingmin Gu ),( Changjiang Sun ),( Xin Feng ),( Wenyu Han ),( Jianxia Jiang ),( Liancheng Lei ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.1
Meningitis caused by Streptococcus suis serotype 2 (S. suis 2) is a great threat to the pig industry and human health. Virulence factors associated with the pathogenesis of meningitis have yet to be clearly defined, even though many potential S. suis 2 virulence factors have been identified. This greatly hinders the progress of S. suis 2 meningitis pathogenesis research. In this study, a co-culture blood-brain barrier (BBB) model was established using primary porcine brain microvascular endothelial cells and astrocytes, and the whole genome library of S. suis 2 was constructed using phage display technology. Finally, a total of 14 potential virulence factors contributing to S. suis 2 adherence to and invasion of the BBB were selected by analyzing the interactions between the phage library and the co-culture model. Twelve of these factors have not been previously reported in meningitis-related research. The data provide valuable insight into the pathogenesis of S. suis 2 meningitis and potential targets for the development of drug therapies.
Polynomial complexity of primal-dual interior-point methods for convex quadratic programming
Zhongyi Liu,Wenyu Sun,Raimundo J.B. de Sampaio,J.B. DE SAMPAIO 한국전산응용수학회 2009 Journal of applied mathematics & informatics Vol.27 No.3
Recently, Peng et al. proposed a primal-dual interior-point method with new search direction and self-regular proximity for LP. This new large-update method has the currently best theoretical performance with polynomial complexity of O(n<수식> log <수식>). In this paper we use this search direction to propose a primal-dual interior-point method for con- vex quadratic programming (QP). We overcome the difficulty in analyz- ing the complexity of the primal-dual interior-point methods for convex quadratic programming, and obtain the same polynomial O(n<수식> log <수식>) for convex quadratic programming. Recently, Peng et al. proposed a primal-dual interior-point method with new search direction and self-regular proximity for LP. This new large-update method has the currently best theoretical performance with polynomial complexity of O(n<수식> log <수식>). In this paper we use this search direction to propose a primal-dual interior-point method for con- vex quadratic programming (QP). We overcome the difficulty in analyz- ing the complexity of the primal-dual interior-point methods for convex quadratic programming, and obtain the same polynomial O(n<수식> log <수식>) for convex quadratic programming.