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Cui, Sheng-Yun,Kim, Seung-Jin,Jo, Sung-Chan,Lee, Yong-Moon,Lee, Yong-Ill Korean Chemical Society 2005 Bulletin of the Korean Chemical Society Vol.26 No.8
A combination of electrospray ionization and tandem mass spectrometry was used to characterize the scavenging reactions of acrylamide (AA) in the presence of glutathione (GSH) in vitro. In the presence of GSH, AA was deactivated effectively and scavenged by reactions consuming small amount of GSH. Reaction products and structural information were identified using collision-induced dissociation (CID) in an ion trap mass spectrometer. In the mixture of GSH and AA, significant increase in abundance of fragment ion peak was observed at m/z 233, which was identified as $[Cys-Glu]^+$, formed by the elimination of glycine moiety of GSH. GSH also contributes to the AA scavenging reaction by conjugating with AA through the sulfhydryl group in cysteine moiety. The probable scavenging reaction pathway of AA in the presence of GSH has been proposed based on the CID experimental data.
Yun-yun Chen,Fen-ping Cui,Fang Gu,Ying-ying Zhang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.11
In this paper, the feasibility of using a one-temperature model to determine plasma’s temperatureby measuring its refractive index is studied based on the consideration that many plasma flow fieldsare not in local thermodynamic equilibrium (LTE). We compare the refractive indices between theone- and the two-temperature models of an arc plasma, in order to discuss the applicability ofthe one-temperature model in optical diagnosis. We found that the applicability is determined bythe pressure, the temperature ratio between electrons and heavy particles, the probe wavelength,and the chosen optical method’s refractive index measurement precision. Consequently, a commonmodel is deduced to describe the refractive index of plasma whether it be in LTE or not. In a word,this study is crucial to better apply optical methods based on measurements of the refractive indexto diagnose plasma flow fields.
Correlations of Tumor-associated Macrophage Subtypes with Liver Metastases of Colorectal Cancer
Cui, Yun-Long,Li, Hui-Kai,Zhou, Hong-Yuan,Zhang, Ti,Li, Qiang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Objective: This work aimed to investigate the correlations of tumor-associated macrophages (TAMs) and their subtypes M1 and M2 with liver metastasis of colorectal cancer, and provide useful references for seeking predictors of liver metastasis and studying mechanisms. Methods: 120 patients with colorectal cancer from 2000 to 2009 were divided into low, middle and high liver metastasis groups (group A, B and C, respectively). S-P immunohistochemical staining and microscopic observation were conducted to compare expression in CD68-positive cells (TAMs), CD80-positive cells (M1) and CD163-positive cells (M2) in three groups. Correlations of TAMs, M1, M2, and M2/M1 ratio with clinical and pathological parameters were analyzed. Results: With increase of liver metastatic ability, the number of TAMs decreased gradually, with no significant difference between any two of the three groups (P > 0.05), while the numbers of M1 and M2 were significantly decreased and increased, respectively, with significant difference between any two of three groups (P < 0.05 or P < 0.01). In addition, the M2/M1 ratio increased with increase of liver metastatic ability (P < 0.01). There was no statistical significance of correlation of TAMs with each clinical and pathological parameter. M1 was negatively related with lymphatic metastasis and liver metastatic ability. M2 was positively correlated with preoperative CEA level, lymphatic metastasis, tumor differentiation degree and liver metastatic ability. The same was the case for the M2/M1 ratio. Conclusions: Effects of TAMs on liver metastasis of colorectal cancer do not depend on the total number of TAMs, but on the number and proportion of functional subtypes M1 and M2. M2 number and M2/M1 ratio are more accurate predictors for liver metastasis of colorectal cancer.
최운(Yun Cui),이한구(Hanku Lee),김명진(Myoungjin Kim),이혁주(Hyeokju Lee) 한국정보과학회 2010 한국정보과학회 학술발표논문집 Vol.37 No.2B
최근 통신 네트워크 기술의 비약적인 발전으로 스마트폰과 같은 다양한 모바일 네트워킹 기기들이 나오고 있다. 이러한 시대적 흐름에 따라서 이종 기기 간의 콘텐츠를 공유하고 사용자의 별도의 사전 작업 없이 자동적으로 콘텐츠 공유 기능을 포함하는 미디어 공유 및 연동을 위한 플랫폼 개발이 중요한 이슈로 부각되어 지고 있다. 본 논문에서 제안하고자 하는 UPnP 기반의 미디어 공유 플랫폼은 미디어 콘텐츠(사진, 음악, 영상)의 공유와 분배를 가능하게 하는 홈 미디어 기술의 일종이다. UPnP 기반의 미디어 공유 플랫폼을 사용하는 기기들은 네트워크를 통해 연결되어 있으며 디바이스들은 별도의 사전 설치 없이 상호 인식하고 디바이스에 저장되어 있는 미디어의 정보를 공유할 수 있다. 이 논문의 주요 목표는 디바이스 간에 미디어 콘텐츠의 공유와 분배를 지원하는 UPnP 기반의 플랫폼을 설계하고 구현하는 것이다.
Mouse Orthotopic Lung Cancer Model Induced by PC14PE6
Zheng Yun Cui,안진석,Jee Yun Lee,Won Seog Kim,Ho Yeong Lim,Hyun Jung Jeon,Soo Won Suh,김진훈,공원호,Ji Min Kang,Do Hyun Nam,박근칠 대한암학회 2006 Cancer Research and Treatment Vol.38 No.4
Purpose: This study was undertaken to investigate in detail the xenograft mouse orthotopic lung cancer model induced by PC14PE6 adenocarcinoma cells.Materials and Methods: Three cell doses (0.5×106; 1×106; 2×106) of PC14PE6 cells were injected into the lungs of male BALB/c nude mice by the intrathoracic injection method. The lung and other organs, including brain, liver, spleen, kidney, muscle, adrenal gland, and lymph node on knee, were removed and stained with H/E to detect the presence of tumor cells. Results: The reliable tumorigenicity time in the PC14PE6 adenocarcinoma cell-inoculated BALB/c nude mouse was 10 days after intrathoracic injection. The average life span of the three groups after inoculation was 14 days in the 2×106 cells inoculum group; 25 days in the 1×106 cells inoculum group; and 32 days in the 0.5×106 cells inoculum group. The PC14PE6 adenocarcinoma cells induced orthotopic lung cancer limited within the thorax. Conclusions: This orthotopic lung cancer model is an efficient cancer model with easy inoculation methods, rapid and high tumorigenicity, and simple monitoring methods for metastasis. (Cancer Res Treat. 2006;38:234-239) Purpose: This study was undertaken to investigate in detail the xenograft mouse orthotopic lung cancer model induced by PC14PE6 adenocarcinoma cells.Materials and Methods: Three cell doses (0.5×106; 1×106; 2×106) of PC14PE6 cells were injected into the lungs of male BALB/c nude mice by the intrathoracic injection method. The lung and other organs, including brain, liver, spleen, kidney, muscle, adrenal gland, and lymph node on knee, were removed and stained with H/E to detect the presence of tumor cells.Results: The reliable tumorigenicity time in the PC14PE6 adenocarcinoma cell-inoculated BALB/c nude mouse was 10 days after intrathoracic injection. The average life span of the three groups after inoculation was 14 days in the 2×106 cells inoculum group; 25 days in the 1×106 cells inoculum group; and 32 days in the 0.5×106 cells inoculum group. The PC14PE6 adenocarcinoma cells induced orthotopic lung cancer limited within the thorax.Conclusions: This orthotopic lung cancer model is an efficient cancer model with easy inoculation methods, rapid and high tumorigenicity, and simple monitoring methods for metastasis. (Cancer Res Treat. 2006;38:234-239)