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      • 아시아 사회보장정책 비교연구 - 아시아 주요국 사회보장체계 비교를 중심으로

        노대명,( Goishi Norimichi ),( Wang Chunguang ),( Ku Yeun Wen ),( Somchai Jitsuchon ),( Giang Thanh Long ),김근혜 한국보건사회연구원 2016 한국보건사회연구원 연구보고서 Vol.2016 No.-

        1990년대 동아시아 복지국가에 대한 연구는 상당 부분 서구 복지국가의 역사적 경험에서 영향을 받았다고 말할 수 있다. 구체적으로는 복지레짐에 대한 에스핑-앤더슨의 이론의 영향을 받아 많은 연구자가 아시아 복지국가를 비교연구해왔다. 하지만 최근의 연구들은 아시아 연구자들에 의해 주도되고 있으며 이들은 아시아 각국의 사회보장체계에 대한 비교연구를 매우 중요한 학문적·정책적 현안으로 인식하고 있다. 이들은 이 지역의 복지국가에 대한 내부로부터의 비판적 성찰을 시작한 것이라고 보아도 무방할 것이다. 이 연구에서 각 저자들은 기존의 동아시아 복지레짐 등과 같은 담론을 채택하기보다 아시아 복지국가의 다양한 모델과 경로를 있는 그대로 보여주고자 하였다. 한국·일본·중국·대만·태국·베트남의 여섯 연구자는 각국 사회보장정책의 주요 현안과 개혁동향을 자세히 설명하고 있다. 일본의 경우 아베 신조 정부는 고령화 관련 사회지출이 급격히 증가하는 상황에서 사회보장시스템에 대한 실질적인 구조개혁을 추진해 왔다. 그것은 다음 몇 가지로 요약할 수 있다. 1) 74세 이상 노인들의 의료비 부담을 20%까지 인상하고 2) 퇴직과 공적연금 수급 연령을 65세에서 67세로 인상하며 3) 연평균소득 대비 공적연금의 비율을 50% 이하로 낮추는 조치 등이다. 흥미로운 점은 일본 정부가 사회보험의 가입과 수급범위를 파트타임 노동자 등 비정규직 노동자를 보호할 수 있도록 확장하였다는 점이다. 이로써 이원화된 노동시장 구조로 인해 발생하는 소득불평등을 해소하고 청년들을 위한 일자리 창출을 촉진하려는 것이다. 중국의 사회보장체계는 경제성장뿐 아니라 소득분배와 빈곤완화, 그리고 사회결속력 유지 등과 관련해 더욱 중요한 역할을 수행할 것으로 예상된다. 물론 중국이 빈곤완화와 관련해 매우 큰 성과를 거두었다고 하지만 소득불평등 또는 소득격차를 축소하는 데서는 그다지 큰 성과를 거두지 못했다. 이러한 소득분배구조 악화는 도시나 농촌 지역을 막론하고 발생하고 있으며 그것은 개혁개방 초기보다도 심각한 수준이다. 이러한 이유로 중국의 사회보장체계는 추가적인 개혁을 필요로 하는 것이다. 이는 핵심 사회보험제도와 사회부조제도의 적용범위를 확대해야 할 뿐 아니라 동일한 사회보장체계에서 집단 간, 지역 간 불평등을 해소해야 하기 때문이다. 대만에서 사회보장제도는 1990년대 법정복지프로그램이 도입되면서 빠르게 확장될 수 있었다. 그것은 국민건강보험, 실업보험, 노령수당, 아동 및 여성을 위한 반폭력 보호프로그램 등이다. 그리고 국민연금보험과 관련된 많은 정책적 논의를 거쳐 2007년 법률이 제정되었고 이듬해 시행되기에 이르렀다. 대만 또한 인구고령화와 고용불안의 심화 문제에 직면해 있으며 이 문제를 해결하기 위해 한편으로는 장기요양보험제도를 도입하고 다른 한편으로는 공적연금제도의 지속가능성을 높이기 위한 개혁에 많은 관심을 기울이고 있다. 태국에서 사회보장체계는 크게 두 가지로 구성되어 있다. 하나는 사회보장체제(Social Security Scheme: SSS)라 불리는 것으로 1954년 사회보험법이 제정되고 2015년 최근의 개혁이 있을 때까지 많은 개정이 있었다. 사회보장체제란 다양한 사회보험 프로그램, 즉 건강보험·출산지원·장례급여·장애수당·아동지원수당·실업급여 등을 포괄하는 것이다. 하지만 문제는 사회보장체제의 보장범위가 매우 좁아 전체 노동인구의 3분의 1을 보호하는 데 그치고 있다는 점이다. 다른 하나는 조세기반형 프로그램으로 보편사회연금·보편의료돌봄·보편장애지원·상병지원수당 등으로 구성되어 있다. 이 제도는 위에 언급한 사회보장체계에 가입하지 못한 집단을 대상으로 하는 것이다. 태국 사회보장체계의 당면한 문제는 대표적 프로그램의 보장범위가 매우 좁아 지속적인 확대가 필요하다는 점이다. 그리고 다양한 제도와 집단 간의 격차가 크다는 점이다. 복지 확대를 뒷받침할 수 있는 재정적 지속가능성의 문제 또한 제기되고 있는 것이다. 베트남의 사회보장체계는 현재 다음과 같은 과제를 안고 있다. 첫째, 사회연금체제의 지속가능성을 담보하는 일이다. 둘째, 복지급여의 효율성을 제고하기 위해 수급자 파악을 보다 정교하게 하는 일이다. 이를 위해서는 생애주기별 접근을 통해 삶의 단계별로 사람들이 처하게 되는 사회적 위험을 파악함으로써 정책과 프로그램이 이러한 위험에 효과적으로 대처할 수 있게 해야 하는 것이다. 셋째, 복지프로그램의 커버리지, 보장범위를 확대하는 것이다. 특히 농어촌 지역의 가난한 노인을 위해 사회연금 적용범위를 확대하는 것이 핵심이다. 넷째는 복지급여 전달체계를 개선하는 것이다. 끝으로 사회보장체계를 모니터링하고 평가할 수 있는 시스템을 ???求?것이다. 끝으로 한국의 사회보장체계는 1997년 금융위기 이후 4대 사회보험을 도입하면서 확대되고 강화되었다. 하지만 현행 사회보장체계는 여전히 많은 문제점을 안고 있다. 첫째, 빈곤층과 비정규직 노동자가 여전히 복지급여에서 배제되고 있다는 점이고 둘째, 공적연금과 사회부조제도의 급여수준이 매우 낮다는 점이며 셋째, 복지전달체계가 중앙정부와 지방정부 간, 그리고 중앙부처 간에도 분절화되어 있다는 점이다. 1990년대말부터 인구고령화 및 저출산 문제에 직면한 상황에서 정부는 사회보장체계의 미래에 대한 많은 우려를 표현하고 있다. 지금 한국은 갈림길에 서서 기존의 사회보험 중심체계를 넘어 대안적 사회보장모델을 모색하고 있는 것이다. In the 1990`s, the studies on welfare state in East Asia have been greatly influenced by the experience of western welfare states, accepting Esping-Andersen`s arguments about three worlds of welfare regimes. However recent studies have begun to be led by the asian researchers who recognize the comparative study on social protection in asian countries as important academic and policy issues. It is considered that they have begun the critical reflections from the inside on the welfare state in this region. In this study, the authors intend to show various models and paths of Asian welfare states as they are, without developing the discourse as like East Asian welfare regime. Six authors, from Korea, Japan, China, Taiwan, Thailand and Vietnam, explain the main issues and reform trends in social protection policies in each countries. In Japan, the Abe`s government, given the rapid growth of age-related spending, has implemented substantial structural reforms of the social security system. Some of the examples include : 1) increasing medical co-payments for individuals over 74 years to 20 per cent, 2) raising the retirement and eligibility ages for receiving public pension payments from 65 to 67 years or higher, and 3) reducing the ratio of the pension to average annual earnings to below 50 percent. It is interesting to see that the japanese government tried also to expand social insurance coverage to non-regular workers for the purpose of reducing the labour market duality and boosting youth employment. In China, the social protection system will play an increasingly important role in economic growth, the balance of income distribution, poverty alleviation and maintenance of social cohesion. Although China has made great achievements in poverty alleviation, but has made little progress in terms of narrowing the income gap. Whether it is in urban areas or in rural areas, the income gap is far greater than that at the initial stage of reform. Current social protection system needs further reform, not only to achieve full coverage of main social insurance and social assistance programs, but also to reduce inequality between different groups and different regions in the same security system, to further increase the redistributive effect of the social security system. In Taiwan, it was witnessed a remarkable development of statutory welfare systems in the decade of 1990s, including the realization of the National Health Insurance, unemployment insurance, allowances for elderly people, special protections for children and women against violence. And a lot of policy debates on National Pension Insurance was finally enacted in 2007 and implemented one year later. Faced with the challenges of population ageing and job precarity, now the policy debates pay much attention on the establishment of long-term care system and the reforms for a sustainable pension system. In Thailand, the social protection system consist of two elements : One is the Social Security Scheme(SSS) in which has been implemented by the Social Insurance Act of 1954 and revised several times to 2015. SSS include seven social protection programs : Health insurance, Birth delivery, Death benefit, Disability benefit, Pension, Children assistance benefit, and Unemployment benefit. The problem is that SSS cover only slightly over one third of the labor force. And the other is a tax-based program as like Universal Social Pension, Universal Health Care, Universal Disability Aids, Patient Assistance Grant, etc. The fact that SSS covers only just above one third of workforce indicates the need to expand social protection for working Thai. Another gap in the social projection system is the welfare for young children before school age. Long-term care is also another area that has some gap in term of coverage. The financial sustainability of social protection system will be another problem to solve. In Vietnam, current social protection system is facing the challenges as follow : The first is ensuring fiscal sustainability of the social pension scheme. The second challenge is accu rately identifying beneficiaries for the efficiency of social assistance programs. For this, life-cycle approach will be appropriate in identifying various risks at different stages of life, so that policies and programs will be adaptive to such risks. The third is increasing coverage. Expanding coverage of the social pension scheme to include poor older persons living in rural and coastal areas. The fourth is improving the benefit delivery system. And the final challenge is enhancing the scheme`s monitoring and evaluation system. Finally, the social protection system in Korea has been expanded and strengthened in the aftermath of the 1997 financial crisis, with the introduction and reinforcement of four social insurances systems. However the current system has still many problems : 1) poors and irregular workers excluded from welfare programs, 2) low benefit level of public pension and social assistance, 3) fragmented welfare delivery systems between the central and local governments, and inside the central government. Also given the population ageing and low fertility and the low economic growth since the late 1990s, the government is concerned about the future of social protection system. Korea is now at a crossroads, seeking alternative social protection models beyond the limits of existing social insurance system.

      • KCI등재

        Hollow-structured Pd/TiO2 as a dual functional photocatalyst for methyl orange oxidation and selective reduction of nitrate into nitrogen

        Wen-Min Wang,Shi-Jer Tseng,Yu-Shuan Huang,Qian-Yuan Wu,Wen-Long Wang,Jerry J. Wu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.119 No.-

        Nitrate pollution in wastewater has posed a threat to human health and the environment. Photocatalyticreduction is a promising technology to remove nitrate due to its high adaptability, low cost, and high efficiency. However, there is a great challenge to design photocatalyst with high nitrate reduction and highselectivity of nitrogen (N2) yield. In this study, a novel hollow-structured Pd/TiO2 (PHT1) photocatalyst issynthesized with large specific surface area (SBET) and pore volume, strong UV adsorption, high reductionpotential than nitrate to nitrite, high charge transfer rate, and low electron-hole recombination rate. PHT1 exhibits a superior photocatalytic activity on the removal of methyl orange and nitrate. In addition,PHT1 exhibits high N2 selectivity (>95 %). A lower pH can promote the reduction of nitrate and the selectivityof N2 by PHT1. Electrons (e-) and CO2– are the main active species for nitrate reduction with OH asauxiliary radicals. Three main pathways for nitrate reduction are proposed: i) the reaction with formicacid under acidic conditions; ii) the reduction by electrons and the loaded Pd of photocatalyst to captureelectrons to inhibit electron-hole recombination; iii) the reduction by CO2 – generated from formic acidoxidation by OH.

      • Research on the Shared-network of SMV and GOOSE in Smart Substation

        Wang, Wen-Long,Liu, Ming-Hui,Zhao, Xi-Cai 대한전기학회 2014 The Journal of International Council on Electrical Vol.4 No.2

        The network structure of the smart substation in common use was introduced, and the technical problem of the shared-network of sampled measured value (SMV) and generic object oriented substation event (GOOSE) was analyzed, such as the processing ability of network device and the intelligent device, the data real-time property and the network reliability, the effects to the substation in the condition of network fault, and so on. On this basis, the feasibility of the shared-network of SMV and GOOSE was discussed, the implement scheme were presented, and eventually came to the solution of the shared-network of SMV and GOOSE, which based on the applications of the message priority control, restricting the switch number, virtual local area network (VLAN) and GARP multicast registration protocol (GMRP) classification flow control, etc. In the test-bed, the cases of shared-network and separate-network of SMV and GOOSE were compared and analyzed, and the result was valuable for reference.

      • SCIESCOPUSKCI등재
      • SCIESCOPUSKCI등재

        Heavy concrete shielding properties for carbon therapy

        Jin-Long Wang,Jiade J Lu,Da-Jun Ding,Wen-Hua Jiang,Ya-Dong Li,Rui Qiu,Hui Zhang,Xiao-Zhong Wang,Huo-Sheng Ruan,Yan-Bing Teng,Xiao-Guang Wu,Yun Zheng,Zi-Hao Zhao,Kai-Zhong Liao,Huan-Cheng Mai,Xiao-Dong Korean Nuclear Society 2023 Nuclear Engineering and Technology Vol.55 No.6

        As medical facilities are usually built at urban areas, special concrete aggregates and evaluation methods are needed to optimize the design of concrete walls by balancing density, thickness, material composition, cost, and other factors. Carbon treatment rooms require a high radiation shielding requirement, as the neutron yield from carbon therapy is much higher than the neutron yield of protons. In this case study, the maximum carbon energy is 430 MeV/u and the maximum current is 0.27 nA from a hybrid particle therapy system. Hospital or facility construction should consider this requirement to design a special heavy concrete. In this work, magnetite is adopted as the major aggregate. Density is determined mainly by the major aggregate content of magnetite, and a heavy concrete test block was constructed for structural tests. The compressive strength is 35.7 MPa. The density ranges from 3.65 g/cm<sup>3</sup> to 4.14 g/cm<sup>3</sup>, and the iron mass content ranges from 53.78% to 60.38% from the 12 cored sample measurements. It was found that there is a linear relationship between density and iron content, and mixing impurities should be the major reason leading to the nonuniform element and density distribution. The effect of this nonuniformity on radiation shielding properties for a carbon treatment room is investigated by three groups of Monte Carlo simulations. Higher density dominates to reduce shielding thickness. However, a higher content of high-Z elements will weaken the shielding strength, especially at a lower dose rate threshold and vice versa. The weakened side effect of a high iron content on the shielding property is obvious at 2.5 µSv=h. Therefore, we should not blindly pursue high Z content in engineering. If the thickness is constrained to 2 m, then the density can be reduced to 3.3 g/cm<sup>3</sup>, which will save cost by reducing the magnetite composition with 50.44% iron content. If a higher density of 3.9 g/cm<sup>3</sup> with 57.65% iron content is selected for construction, then the thickness of the wall can be reduced to 174.2 cm, which will save space for equipment installation.

      • Three-Port Laparoscopic Exploration is not Sufficient for Patients with T4 Gastric Cancer

        Huang, Hua,Jin, Jie-Jie,Long, Zi-Wen,Wang, Wei,Cai, Hong,Liu, Xiao-Wen,Yu, Hong-Mei,Zhang, Li-Wen,Wang, Ya-Nong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Gastric cancer continues to be a leading cause of cancer death. The majority of patients with gastric adenocarcinoma in China present with advanced disease. Ruling out unresectable cancers from an unnecessary "open" exploration is very important. The aim of this study was to assess the value of five-port anatomical laparoscopic exploration in T4 gastric cancer in comparison with three-port laparoscopic exploration and laparotomy exploration. We conducted a retrospective study on 126 patients with T4 stage scheduled for D2 curative gastrectomy based on computed tomography (CT) staging at Department of Gastric Cancer and Soft Tissue Sarcoma, Fudan University Shanghai Cancer Center, from Apr. 2011 to Apr. 2013. Laparotomy exploration (Group I), three-port laparoscopic exploration (Group II) or five-port anatomical laparoscopic exploration (Group III) were performed prior to radical gastrectomy. Accuracy rate for feasibility of D2 curative gastrectomy in laparotomy exploration and five-port anatomical laparoscopic exploration groups was higher than that in the three-port laparoscopic exploration group. Five-port anatomical laparoscopic exploration group had the highest accuracy resection rate (Group I vs Group II vs Group III,92.6% vs78.6% vs 97.7%; p<0.05) and shorter length of hospitalization (Group I vs Group II vs Group III, $9.58{\pm}4.17$ vs $6.13{\pm}2.85$ vs $5.00{\pm}1.81$; p<0.001). Three-port laparoscopic exploration has low accuracy rate for assessing feasibility of D2 curative gastrectomy and five-port anatomical laparoscopic exploration should be performed on patients with T4 gastric cancer.

      • SCIESCOPUSKCI등재

        Review of researches on coupled system and CFD codes

        Long, Jianping,Zhang, Bin,Yang, Bao-Wen,Wang, Sipeng Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.9

        At present, most of the widely used system codes for nuclear safety analysis are one-dimensional, which cannot effectively simulate the flow field of the reactor core or other structures. This is true even for the system codes containing three-dimensional modules with limited three-dimensional simulation function such as RELAP-3D. In contrast, the computational fluid dynamics (CFD) codes excel at providing a detailed three-dimensional flow field of the reactor core or other components; however, the computational domain is relatively small and results in the very high computing resource consuming. Therefore, the development of coupling codes, which can make comprehensive use of the advantages of system and CFD codes, has become a research focus. In this paper, a review focus on the researches of coupled CFD and thermal-hydraulic system codes was carried out, which summarized the method of coupling, the data transfer processing between CFD and system codes, and the verification and validation (V&V) of coupled codes. Furthermore, a series of problems associated with the coupling procedure have been identified, which provide the general direction for the development and V&V efforts of coupled codes.

      • KCI등재

        CTLA4-Ig protects tacrolimus-induced oxidative stress via inhibiting the AKT/FOXO3 signaling pathway in rats

        Long Jin,Nan Shen,Xinyu Wen,Weidong Wang,Sun Woo Lim,양철우 대한내과학회 2023 The Korean Journal of Internal Medicine Vol.38 No.3

        Background/Aims: Although the conversion from tacrolimus (TAC) to cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin (CTLA4-Ig) is effective in reducing TAC-induced nephrotoxicity, it remains unclear whether CTLA4-Ig has a direct effect on TAC-induced renal injury. In this study, we evaluated the effects of CTLA4-Ig on TAC-induced renal injury in terms of oxidative stress. Methods: In vitro study was performed to assess the effect of CTLA4-Ig on TAC-induced cell death, reactive oxygen species (ROS), apoptosis, and the protein kinase B (AKT)/forkhead transcription factor (FOXO) 3 pathway in human kidney 2 cells. In the in vivo study, the effect of CTLA4-Ig on TAC-induced renal injury was evaluated using renal function, histopathology, markers of oxidative stress (8-hydroxy-2’-deoxyguanosine) and metabolites (4-hydroxy-2-hexenal, catalase, glutathione S-transferase, and glutathione reductase), and activation of the AKT/FOXO3 pathway with insulin-like growth factor 1 (IGF-1). Results: CTLA4-Ig significantly decreased cell death, ROS, and apoptosis caused by TAC. TAC treatment increased apoptotic cell death and apoptosis-related proteins (increased Bcl-2-associated X protein and caspase-3 and decreased Bcl-2), but it was reversed by CTLA4-Ig treatment. The activation of p-AKT and p-FOXO3 by TAC decreased with CTLA4-Ig treatment. TAC-induced renal dysfunction and oxidative marker levels were significantly improved by CTLA4-Ig in vivo. Concomitant IGF- 1 treatment abolished the effects of CTLA4-Ig. Conclusions: CTLA4-Ig has a direct protective effect on TAC-induced renal injury via the inhibition of AKT/FOXO3 pathway.

      • An Updated Meta-analysis on the Association of X-Ray Repair Cross Complementing Group 1 Codon 399 Polymorphism with Hepatocellular Carcinoma Risk

        Wang, Ya-Dong,Zhai, Wen-Long,Wang, Hai-Yu,Xia, Xiang-Qun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

        Background: A number of studies have reported the association of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism with susceptibility to hepatocellular carcinoma (HCC). However, the results were inconsistent and inconclusive. The aim of this study was to comprehensively explore the association of XRCC1 Arg399Gln variant with HCC risk. Materials and Methods: Systematic searches of PubMed, Elsevier, Science Direct, CNKI and Chinese Biomedical Literature Database were performed. Pooled odds ratio (OR) with 95% confidence intervals (CI) was calculated to estimate the strength of association. Results: Overall, we observed an increased HCC risk among subjects carrying XRCC1 codon 399 Gln/Gln, Arg/Gln and Gln/Gln+Arg/Gln genotypes (OR=1.20, 95%CI: 1.05-1.38, OR=1.16, 95%CI: 1.05-1.28, and OR=1.14, 95%CI: 1.04-1.24, respectively) based on 20 studies including 3374 cases and 4633 controls. In subgroup analysis, we observed an increased risk of XRCC1 codon 399 Gln/Gln, Arg/Gln and Gln/Gln+Arg/Gln polymorphisms for HCC in hospital-based study (OR=1.25, 95%CI: 1.03-1.51, OR=1.21, 95%CI: 1.07-1.36 and OR=1.18, 95%CI: 1.06-1.31, respectively) and in Asian population (OR=1.19, 95%CI: 1.03-1.38, OR=1.17, 95%CI: 1.04-1.30 and OR=1.14, 95%CI: 1.04-1.25, respectively). Limiting the analysis to the studies with controls in agreement with Hardy-Weinberg equilibrium (HWE), we observed an increased HCC risk among Gln/Gln, Arg/Gln and Gln/ Gln+Arg/Gln genotype carriers (OR=1.17, 95%CI: 1.05-1.29, OR=1.12, 95%CI: 1.00-1.25 and OR=1.11, 95%CI: 1.02-1.21, respectively). Conclusions: This updated meta-analysis results suggest that XRCC1 Arg399Gln variants may contribute to HCC risk. Well-designed studies with larger sample size were required to further verify our findings.

      • KCI등재

        MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway

        Long, Zi-Wen,Wu, Jiang-Hong,Hong, Cai,Wang, Ya-Nong,Zhou, Ye Korean Society for Molecular and Cellular Biology 2018 Molecules and cells Vol.41 No.6

        Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumors of the gastrointestinal (GI) tract. In order to investigate a new treatment fot GIST, we hypothesized the effect of miR-374b targeting PTEN gene-mediated PI3K/Akt signal transduction pathway on proliferation and apoptosis of human gastrointestinal stromal tumor (GIST) cells. We obtained GIST tissues and adjacent normal tissues from 143 patients with GIST to measure the levels of miR-374b, PTEN, PI3K, Akt, caspase9, Bax, MMP2, MMP9, ki67, PCNA, P53 and cyclinD1. Finally, cell viability, cell cycle and apoptosis were detected. According to the KFGG analysis of DEGs, PTEN was involved in a variety of signaling pathways and miRs were associated with cancer development. The results showed that MiR-374b was highly expressed, while PTEN was downregulated in the GIST tissues. The levels of miR-374b, PI3K, AKT and PTEN were related to tumor diameter and pathological stage. Additionally, miR-374b increased the mRNA and protein levels of PI3K, Akt, MMP2, MMP9, P53 and cyclinD1, suggesting that miR-374b activates PI3K/Akt signaling pathway in GIST-T1 cells. Moreover, MiR374b promoted cell viability, migration, invasion, and cell cycle entry, and inhibited apoptosis in GIST cells. Taken together, the results indicated that miR-374b promotes viability and inhibits apoptosis of human GIST cells by targeting PTEN gene through the PI3K/Akt signaling pathway. Thus, this study provides a new potential target for GIST treatment.

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