Traffic speed mapping with cellular network signaling data by FOSS4G

Wang Weifeng,Zhu Kemin,Liu Junli,Hu Jinghao,Raganvan Venkatesh,Xu Jiang,Song Xianfeng 대한공간정보학회 2022 Spatial Information Research Vol.30 No.2

Mapping traffic speed on road networks is crucial for urban traffic management and the development of intelligent transportation systems. Traditionally, information regarding traffic speed can be obtained from locationfixed sensors, such as loop detectors and cameras; however, these methods are limited to major road crosses. Recently, a considerable attention has been paid to utilizing vehicles with mobile phones as probes for collecting traffic information. This study proposes an open-source GIS approach to map traffic speeds in a road network. First, public service vehicles (PSVs) were identified from cellular network signaling data by measuring the similarity between cell-ID trajectories and bus routes. Then, the cell-ID trajectories of PSVs were refined into high-quality spatiotemporal trajectories, and projected onto the road network via heuristic global optimization. Finally, hourly traffic speed maps were computed by weighing the speeds of the PSVs in the road network. The approach was implemented using free and open source software for geospatial mapping stacks of toolkits (Python, TimescaleDB/PostGIS, Pandas/Pygmo2, and Matplotlib/Seaborn); this application demonstrated good results using cellular network signaling data and GPS trajectories collected in Huilongguan district, Beijing, China. Moreover, this demonstration illustrates that probe mobile monitoring is emerging as a critical technology for traffic monitoring supplements, which can help develop a comprehensive view of the roads and reduce the cost of monitoring a large area.

Traffic speed mapping with cellular network signaling data by FOSS4G

Wang Weifeng,Zhu Kemin,Liu Junli,Hu Jinghao,Raganvan Venkatesh,Xu Jiang,Song Xianfeng 대한공간정보학회 2022 Spatial Information Research Vol.30 No.1

Mapping traffic speed on road networks is crucial for urban traffic management and the development of intelligent transportation systems. Traditionally, information regarding traffic speed can be obtained from locationfixed sensors, such as loop detectors and cameras; however, these methods are limited to major road crosses. Recently, a considerable attention has been paid to utilizing vehicles with mobile phones as probes for collecting traffic information. This study proposes an open-source GIS approach to map traffic speeds in a road network. First, public service vehicles (PSVs) were identified from cellular network signaling data by measuring the similarity between cell-ID trajectories and bus routes. Then, the cell-ID trajectories of PSVs were refined into high-quality spatiotemporal trajectories, and projected onto the road network via heuristic global optimization. Finally, hourly traffic speed maps were computed by weighing the speeds of the PSVs in the road network. The approach was implemented using free and open source software for geospatial mapping stacks of toolkits (Python, TimescaleDB/PostGIS, Pandas/Pygmo2, and Matplotlib/Seaborn); this application demonstrated good results using cellular network signaling data and GPS trajectories collected in Huilongguan district, Beijing, China. Moreover, this demonstration illustrates that probe mobile monitoring is emerging as a critical technology for traffic monitoring supplements, which can help develop a comprehensive view of the roads and reduce the cost of monitoring a large area.

Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

Zhang Weifeng,Li Gaocai,Luo Rongjin,Lei Jie,Song Yu,Wang Bingjin,Ma Liang,Liao Zhiwei,Ke Wencan,Liu Hui,Hua Wenbin,Zhao Kangcheng,Feng Xiaobo,Wu Xinghuo,Zhang Yukun,Wang Kun,Yang Cao 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Low back pain (LBP) is a major musculoskeletal disorder and the socioeconomic problem with a high prevalence that mainly involves intervertebral disc (IVD) degeneration, characterized by progressive nucleus pulposus (NP) cell death and the development of an inflammatory microenvironment in NP tissue. Excessively accumulated cytosolic DNA acts as a damage-associated molecular pattern (DAMP) that is monitored by the cGAS-STING axis to trigger the immune response in many degenerative diseases. NLRP3 inflammasome-dependent pyroptosis is a type of inflammatory programmed death that promotes a chronic inflammatory response and tissue degeneration. However, the relationship between the cGAS-STING axis and NLRP3 inflammasome-induced pyroptosis in the pathogenesis of IVD degeneration remains unclear. Here, we used magnetic resonance imaging (MRI) and histopathology to demonstrate that cGAS, STING, and NLRP3 are associated with the degree of IVD degeneration. Oxidative stress induced cGAS-STING axis activation and NLRP3 inflammasome-mediated pyroptosis in a STING-dependent manner in human NP cells. Interestingly, the canonical morphological and functional characteristics of mitochondrial permeability transition pore (mPTP) opening with the cytosolic escape of mitochondrial DNA (mtDNA) were observed in human NP cells under oxidative stress. Furthermore, the administration of a specific pharmacological inhibitor of mPTP and self-mtDNA cytosolic leakage effectively reduced NLRP3 inflammasome-mediated pyroptotic NP cell death and microenvironmental inflammation in vitro and degenerative progression in a rat disc needle puncture model. Collectively, these data highlight the critical roles of the cGAS-STING-NLRP3 axis and pyroptosis in the progression of IVD degeneration and provide promising therapeutic approaches for discogenic LBP.

Research and Application of Fiber Bragg Grating Sensor in Geological Disaster Automation Monitoring

Liu Yimin,Wang Jie,Ji Weifeng,Zhou Ce,Chen Wenjun 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10

In this paper, fiber grating technology is used for accurately measure stresses, temperature and displacement. The paper introduces the basic principles of FBG technology and the wavelength demodulation method of FBG sensors, and put fiber grating technology into practical engineering projects. The paper design a optical fiber grating real-time automation monitoring system to distributed measure stress, temperature and displacement in geological disaster body, to provide effective technical supports for geological disaster prevention and mitigation.

A Meta-Analysis of the Accuracy of Prostate Cancer Studies Which Use Magnetic Resonance Spectroscopy as a Diagnostic Tool

Peng Wang,You-min Guo,Min Liu,Yong-qian Qiang,Xiao-juan Guo,Yi-li Zhang,Xiao-Yi Duan,Qiu-Juan Zhang,Weifeng Liang 대한영상의학회 2008 Korean Journal of Radiology Vol.9 No.5

Objective: We aimed to do a meta-analysis of the existing literature to assess the accuracy of prostate cancer studies which use magnetic resonance spectroscopy (MRS) as a diagnostic tool. Materials and Methods: Prospectively, independent, blind studies were selected from the Cochrane library, Pubmed, and other network databases. The criteria for inclusion and exclusion in this study referenced the criteria of diagnostic research published by the Cochrane center. The statistical analysis was adopted by using Meta-Test version 6.0. Using the homogeneity test, a statistical effect model was chosen to calculate different pooled weighted values of sensitivity, specificity, and the corresponding 95% confidence intervals (95% CI). The summary receiver operating characteristic (SROC) curves method was used to assess the results. Results: We chose two cut-off values (0.75 and 0.86) as the diagnostic criteria for discriminating between benign and malignant. In the first diagnostic criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI (expressed as area under curve [AUC]) were 0.82 (0.73, 0.89), 0.68 (0.58, 0.76), and 83.4% (74.97, 91.83). In the second criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI were 0.64 (0.55, 0.72), 0.86 (0.79, 0.91) and 82.7% (68.73, 96.68). Conclusion: As a new method in the diagnostic of prostate cancer, MRS has a better applied value compared to other common modalities. Ultimately, large scale RCT randomized controlled trial studies are necessary to assess its clinical value. Objective: We aimed to do a meta-analysis of the existing literature to assess the accuracy of prostate cancer studies which use magnetic resonance spectroscopy (MRS) as a diagnostic tool. Materials and Methods: Prospectively, independent, blind studies were selected from the Cochrane library, Pubmed, and other network databases. The criteria for inclusion and exclusion in this study referenced the criteria of diagnostic research published by the Cochrane center. The statistical analysis was adopted by using Meta-Test version 6.0. Using the homogeneity test, a statistical effect model was chosen to calculate different pooled weighted values of sensitivity, specificity, and the corresponding 95% confidence intervals (95% CI). The summary receiver operating characteristic (SROC) curves method was used to assess the results. Results: We chose two cut-off values (0.75 and 0.86) as the diagnostic criteria for discriminating between benign and malignant. In the first diagnostic criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI (expressed as area under curve [AUC]) were 0.82 (0.73, 0.89), 0.68 (0.58, 0.76), and 83.4% (74.97, 91.83). In the second criterion, the pooled weighted sensitivity, specificity, and corresponding 95% CI were 0.64 (0.55, 0.72), 0.86 (0.79, 0.91) and 82.7% (68.73, 96.68). Conclusion: As a new method in the diagnostic of prostate cancer, MRS has a better applied value compared to other common modalities. Ultimately, large scale RCT randomized controlled trial studies are necessary to assess its clinical value.

Fabrication of Cu2SnS3 Thin Films by Ethanol-Ammonium Solution Process by Doctor-Blade Technique

Yaguang Wang,Jianmin Li,Cong Xue,Yan Zhang,Guoshun Jiang,Weifeng Liu,Changfei Zhu 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.6

In the present study, a low-cost and simple method is applied to fabricate Cu2SnS3(CTS) thin films. Namely CTS thin films are prepared by a doctor-blade method with aslurry dissolving the Cu2O and SnS powders obtained from CBD reaction solution intoethanol-ammonium solvents. Series of characterization methods including XRD,Raman spectra, SEM and UV-Vis analyses are introduced to investigate the phasestructure, morphology and optical properties of CTS thin films. As a result, monoclinicCTS films have been obtained with the disappearance of binary phases CuS and SnS2while increasing the annealing temperature and time, high quality monoclinic CTS thinfilms consisting of compact and large grains have been successfully prepared by thisethanol-ammonium method. Moreover, the secondary phase Cu2Sn3S7 is also observedduring the annealing process. In addition, the post-annealed CTS film with a band-gapabout 0.89 eV shows excellent absorbance between 400 and 1200 nm, which is properfor the bottom layer in multi-junction thin film solar cells.

Cauchy mutation boosted Harris hawk algorithm: optimal performance design and engineering applications

Shan Weifeng,He Xinxin,Liu Haijun,Heidari Ali Asghar,Wang Maofa,Cai Zhennao,Chen Huiling 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.2

Harris hawks optimization (HHO) has been accepted as one of the well-established swarm-based methods in the community of optimization and machine learning that primarily works based on multiple dynamic features and various exploratory and exploitative traits. Compared with other optimization algorithms, it has been observed that HHO can obtain high-quality solutions for continuous and constrained complex and real-world problems. While there is a wide variety of strategies in the HHO for dealing with diverse situations, there are chances for sluggish performance, where the convergence rate can gradually slow with time, and the HHO may stay stuck in the current relatively better place and may be unable to explore other better areas. To mitigate this concern, this paper combines the Cauchy mutation mechanism into the HHO algorithm named CMHHO. This idea can boost performance and provide a promising optimizer for solving complex optimization problems. The Cauchy mutation mechanism can speed up the convergence of the solution and help HHO explore more promising regions compared to its basic release. On 30 IEEE CEC2017 benchmark functions, the study compared the proposed CMHHO with various conventional and advanced metaheuristics to validate its performance and quality of solutions. It has been found through experiments that the overall optimization performance of CMHHO is far superior to all competitors. The CMHHO method is applied to four engineering challenges to investigate the capabilities of the proposed algorithm in solving real-world problems, and experimental results show that the suggested algorithm is more successful than existing algorithms.

Influence of the axial radius of rigid arc-shaped rollers in 3D surface rolling

Xintong Wang,Ming-Zhe Li,Yuwei Liu,Xiang Chang,Weifeng Yang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.8

The research and development of flexible forming technology have a crucial role in the personalized production and manufacturing of three-dimensional (3D) surface sheet metal parts. Three-dimensional surface rolling with rigid arc-shaped rollers (TSRRAR), a new flexible forming technology, was investigated to effortlessly produce 3D surface parts. Numerical simulation and experimental analysis mainly include data at four values of the difference in axial radius of roller (-2, 2, 6 and 10 mm) to explore this technology’s forming ability. It was demonstrated that various shapes could be obtained only based on one group of rollers. The maximum resultant force decreased from 3.07 to 2.21 KN, and the required maximum compression rate from 4.22 to 2.48 % with the same longitudinal curvature radius (179 mm) to be obtained. Therefore, the forming difficulty can be reduced by selecting the difference in axial radius of roller.

Ion-Imprinted Polymers Modified Sensor for Electrochemical Detection of Cu2+

Zhuolin An,Weifeng Liu,Qi Liang,Guang Yan,Lei Qin,Lin Chen,Meiling Wang,Yongzhen Yang,Xuguang Liu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.12

An electrochemical sensor (Cu2+-IIPs/GCE) was developed for detection of Cu2+ in water. Cu2+-IIPs/GCE was prepared by dispersing Cu2+ imprinted polymers (Cu2+-IIPs) on a preprocessed glassy carbon electrode. Cu2+-IIPs were synthesized on the surface of modified carbon spheres by ion imprinting technology. The electrochemical performance of Cu2+-IIPs/GCE was evaluated by differential pulse voltammetry method. The response of Cu2+-IIPs/GCE to Cu2+ was linear in 1.0 x 10 -5 mol/L to 1.0 x 10 -3 mol/L. The detection limit was 5.99 x 10 -6 mol/L (S/N = 3). The current response value of Cu2+-IIPs/GCE was 2.14 times that of the nonimprinted electrode. These results suggest that Cu2+-IIPs/GCE can detect the concentration of Cu2+ in water, providing a new way for heavy metal ions adsorption and testing.

The effects of deletion of cellobiohydrolase genes on carbon source-dependent growth and enzymatic lignocellulose hydrolysis in Trichoderma reesei

Ren Meibin,Wang Yifan,Liu Guoxin,Zuo Bin,Zhang Yuancheng,Wang Yunhe,Liu Weifeng,Liu Xiangmei,Zhong Yaohua 한국미생물학회 2020 The journal of microbiology Vol.58 No.8

The saprophytic fungus Trichoderma reesei has long been used as a model to study microbial degradation of lignocellulosic biomass. The major cellulolytic enzymes of T. reesei are the cellobiohydrolases CBH1 and CBH2, which constitute more than 70% of total proteins secreted by the fungus. However, their physiological functions and effects on enzymatic hydrolysis of cellulose substrates are not sufficiently elucidated. Here, the cellobiohydrolase-encoding genes cbh1 and cbh2 were deleted, individually or combinatively, by using an auxotrophic marker-recycling technique in T. reesei. When cultured on media with different soluble carbon sources, all three deletion strains (Δcbh1, Δcbh2, and Δcbh1Δcbh2) exhibited no dramatic variation in morphological phenotypes, but their growth rates increased apparently when cultured on soluble cellulase-inducing carbon sources. In addition, Δcbh1 showed dramatically reduced growth and Δcbh1Δcbh2 could hardly grew on microcrystalline cellulose (MCC), whereas all strains grew equally on sodium carboxymethyl cellulose (CMC-Na), suggesting that the influence of the CBHs on growth was carbon source-dependent. Moreover, five representative cellulose substrates were used to analyse the influence of the absence of CBHs on saccharification efficiency. CBH1 deficiency significantly affected the enzymatic hydrolysis rates of various cellulose substrates, where acid pre-treated corn stover (PCS) was influenced the least. CBH2 deficiency reduced the hydrolysis of MCC, PCS, and acid pre-treated and delignified corncob but improved the hydrolysis ability of filter paper. These results demonstrate the specific contributions of CBHs to the hydrolysis of different types of biomass, which could facilitate the development of tailor-made strains with highly efficient hydrolysis enzymes for certain biomass types in the biofuel industry.