A Parametric Study of the Functioning of an Axisymmetric Explosive Separation Device

Guangyu Wang,Quan Wen,Xiaopeng Wang,Yushi Wang 한국항공우주학회 2021 International Journal of Aeronautical and Space Sc Vol.22 No.6

At present, the design and optimization of the linear explosive separation device mainly depends on experiment, which is not only costly but also low efficient. The introduction of finite element analysis prior to experiment may reduce the cost to design a linear explosive separation device. Herein, arbitrary Lagrangian–Eulerian (ALE) numerical method is utilized to investigate the functioning of an axisymmetric explosive separation device. Firstly, several ALE models are validated via explosive separation experiments and photonic Doppler velocimetry (PDV) measurements, and found to have reasonable accuracy. Then, a series of ALE models are developed to study the transient separation process of an axisymmetric explosive separation device. Multiple factors which may influence the process are identified through parametric study. Especially, it is found that the linear density of the explosive core in the detonating cord and the bottom radius of the v-notch on the separation plate are critical for the accumulation of effective plastic strain at the v-notch. In addition, the material of the protection plate and the angle of the v-notch have a certain influence on the effective plastic strain at the v-notch. The material strength of the protection plate almost has little influence on the effective plastic strain at the v-notch. The study may facilitate the optimal design of the axisymmetric explosive separation device.

Online Cutting Temperature Measurement System Based Thermocouple

Wang zhengyu,Yu xiaoyang,Li guanghui,Tan guangyu 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10

In order to measure cutter temperature, the on-line thermocouple temperature measurement system was proposed. In this system, temperature sensing element thermocouple was welded in the flank face close to the cutting edge with double bare wires welding way. With this method, this system has advantages of a single point temperature measurement and no effect on cutter temperature distribution. For a higher sampling rate, two AD were used to sample alternately; and for the convenient signal transmission when the cutter is rotating at high speed, wireless transmission was adopted to transmit thermocouple output signal and cold side temperature signal to the host computer. After temperature compensation to the cold side, the compensated temperature will be real-time displayed, stored and played back. System measurement range is 0 ~ 1300 ° C, and the measurement uncertainty is 0.58%. For 8000rpm rotational speed of XH714D machine, experimental results show that the system can measure cutter temperature online, and has advantages of low cost and great practicability.

Comprehensive analysis of TCR repertoire of COVID-19 patients in different infected stage

Wang Guangyu,Wang Yongsi,Jiang Shaofeng,Fan Wentao,Mo Chune,Gong Weiwei,Chen Hui,He Dan,Huang Jinqing,Ou Minglin,Hou Xianliang 한국유전학회 2022 Genes & Genomics Vol.44 No.7

Background: The current pandemic of coronavirus disease 2019 (COVID-19), transmitted person-to-person by the severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2), poses a threat to global public health. Objective: In this study, we performed the comprehensive analysis of the T cell receptor (TCR) repertoire may contribute to a more in-depth understanding of the pathogenesis of COVID-19. Methods: A comprehensive immunological analysis was performed to explore the features of the TCR repertoire and identified TCR sequences correlated with SARS-CoV-2 viral antigens. Results: we analyzed the COVID-19 patients' TCR repertoires in peripheral blood mononuclear cells (PBMC) which obtained before (baseline), during (acute), and after rehabilitation (convalescent) by ImmunoSEQ-technology, and found that repertoire features of TCRβ-chain (TCRβ) complementary-determining region 3 (CDR3) in COVID-19 patients were remarkable difference, including decreased TCR diversity, abnormal CDR3 length, difference of TRBV/J gene usage and higher TCR sequence overlap. Besides, we identified some COVID-19 disease-associated TCRβ clones, and the abundance of them changed with the progression of the disease. Importantly, these disease-associated TCRβ clones could be used to distinguish COVID-19 patients from healthy controls with high accuracy. Conclusions: We provide a clear understanding of the TCR repertoire of COVID-19 patients, which lays the foundation for better diagnosis and treatment of COVID-19 patients.

Combined effect of Fe2O3 and Cr2O3 on the structure and properties of glass-ceramics prepared from Baotou steel blast furnace slag

Guangyu Wang,Yongsheng Du,Jie Ma,Hongxia Zhang,Shunli Ouyang,Leibo Deng,Hua Chen,Ming Zhao 한양대학교 세라믹연구소 2021 Journal of Ceramic Processing Research Vol.22 No.6

CaO-MgO-Al2O3-SiO2 glass-ceramics were successfully prepared using Baotou Steel BFS as the raw materials, choosing Fe2O3and Cr2O3 as nucleating agents. This paper focused on analyzing the combined effect of Fe2O3 and Cr2O3 on the structure andproperties of the glass-ceramics. Experimental results showed that the crystallization mechanism of glass-ceramics convertedsurface crystallization into bulk crystallization and the main crystalline phase of glass-ceramics changed gradually from augiteto diopside with the decrease of Fe2O3/Cr2O3 ratios. Therefore, an appropriate ratio of Fe2O3/Cr2O3 can act as nuclei forcrystallization of augite with integrated interlocking crystal structure and the physicochemical properties of glass-ceramic canbe improved. Consequently, the fracture mode of glass-ceramic was changed from intercrystalline to mixed transcrystalline/intercrystalline and therefore the average crack length can be shortened. Glass-ceramic with Fe2O3/Cr2O3 ratio of 1 had a highbending strength of 138.93 MPa, Vickers hardness of 7.51 GPa and acid resistance of 97.75%.

Comparison of gastric-jejunum pouch anastomosis and Billroth-II reconstructions after distal gastrectomy: a propensity score matching analysis

Guangyu Chen*,Long Cheng*,Liye Liu,Guode Luo,Ming Li,Yi Wen,Tao Wang,Yongkuan Cao 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.103 No.2

Purpose: Our study aimed to make a propensity score matching (PSM) analysis on the clinical application of gastric- jejunum pouch anastomosis (GJPA) and Billroth-II anastomosis after distal gastrectomy. Methods: We collected clinical data from 249 patients who received distal gastrectomy from January 2016 to July 2020. According to the reconstruction method used, all patients were divided into the Billroth-II group and the GJPA group. Clinical data and operation complications were analyzed. Results: The clinical characteristics of the 2 groups were comparable after PSM. In the Billroth-II group, the incidence rate of delayed gastric emptying was higher than that in the GJPA group. Fewer patients suffered reflux gastritis in the GJPA group. The RGB (residue, gastritis, and bile) scores related to the severity of bile reflux into the remnant stomach, gastritis, and residue were higher in the Billroth-II group. Postoperative nutritional status and Visick classification demonstrated that postoperative subjective feelings in the GJPA group were improved significantly. Conclusion: The application of GJPA in reconstruction after distal gastrectomy is safe, economical, and reliable. This reconstruction improved the quality of life of patients. It is worth popularizing widely in clinical settings.

Definitive extended field intensity-modulated radiotherapy and concurrent cisplatin chemosensitization in the treatment of IB2-IIIB cervical cancer

Guangyu Zhang,Fangfang He,Chunli Fu,Youzhong Zhang,Qiuan Yang,Jianbo Wang,Yufeng Cheng 대한부인종양학회 2014 Journal of Gynecologic Oncology Vol.25 No.1

Objective: To assess the toxicity of delivering extended field intensity-modulated radiotherapy (EF-IMRT) and concurrent cisplatin chemotherapy for locally advanced cervical carcinoma. Methods: Forty-five patients who underwent EF-IMRT and concurrent cisplatin chemotherapy for the treatment of stage IB2 to IIIB cervical cancer were retrospectively reviewed. The clinical target volume included all areas of gross and potentially microscopic disease and regional lymph node regions. All patients underwent high-dose-rate brachytherapy. The acute and late toxicity were scored using the Common Terminology Criteria for Adverse Events and the Radiation Therapy Oncology Group late radiation morbidity scoring criteria, respectively. Results: The median follow-up was 28 months (range, 5 to 62 months). Forty-two patients had a complete response, and three had a persistent disease. Of those 42 patients, 15 patients (35.7%) had recurrence. The regions of recurrence were in-field in 2 patients and out-field in 13 patients. Acute grade ≥3 gastrointestinal, genitourinary and hematologic toxicity occurred in 3, 1, and 9 patients, respectively. Three patients (6.7%) suffered from late grade 3 toxicities. Seven patients experienced ovarian transposition, 5 of those patients (71%) maintained ovarian function. Thirty-eight patients (84.4%) were alive at the last follow-up. Conclusion: Concurrent cisplatin chemotherapy with EF-IMRT was safe. The acute and late toxicities are acceptable. EF-IMRT provides an opportunity to preserve endocrine function for patients with ovarian transposition.

Synthesis of high-performance Ni/Ce0.8Zr0.2O2 catalyst via co-nanocasting method for ethanol dry reforming

Guangyu Shi,Yuanhao Wang,Yafeng Cao,Weijie Cai,Fengzhi Tan 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.12

A Ni/Ce0.8Zr0.2O2 catalyst (NiCeZr-N) was synthesized by a facile co-nanocasting technique for syngas production from ethanol dry reforming. In addition, a series of characterization techniques, such as transmission electron microscopy (TEM), X-ray diffraction (XRD), inductive coupled plasma Emission Spectrometer (ICP), X-ray photoelectron spectroscopy (XPS), Raman and hydrogen temperature programmed reduction (H2-TPR) were selected to evaluate the physicochemical features of the as-prepared catalysts. Indeed, the results indicated that NiCeZr-N catalyst prepared by co-nanocasting method had a smaller particle size (<5 nm), relatively higher specific surface area (39m2/g) and stronger metal-support interaction in comparison with another model catalyst obtained from conventional co-precipitation method (NiCeZr-P). Expectedly, these positive factors enabled NiCeZr-N catalyst to exhibit better activity and stability. Typically, ethanol is completely converted by using NiCeZr-N as catalyst and heating to 700 oC, and CO2 conversion was as high as 65.3%. Interestingly, H2/CO was close to 1.1 at 650 oC, which could be used as feedstocks of Fischer-Tropsch process. Particularly, no obvious fluctuation of ethanol conversion and the product selectivity was observed during 40 h time-on-stream stability test.

An Improved Affinity Propagation Clustering Algorithm Based on Entropy Weight Method and Principal Component Analysis

Wang Limin,Zhang Li,Han Xuming,Ji Qiang,Mu Guangyu,Liu Ying 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.6

Traditional affinity propagation algorithm has inefficient results when conducting clustering analysis of high dimensional data because "dimension effect" lead to difficult find the proper class structure .In view of this, the author proposes an improved algorithm on the basis of Entropy Weight Method and Principal Component Analysis (EWPCA-AP). EWPCA-AP algorithm empowers the sample data by Entropy Weight Method, eliminate data irrelevant attributes by Principal Component Analysis, and travel with neighbor clustering algorithm, realization of high-dimensional data clustering in low dimension space. The numerical result of simulation experiment shows that the new EWPCA-AP algorithm can effectively eliminate the redundancy and irrelevant attributes of data and improve the performance of clustering. In addition, the proposed algorithm is applied in the area of the economy in our country and the clustering result is consistent with the real one. This algorithm provides a new intelligent evaluation method for Chinese economy.

Fermentation parameters, antioxidant capacities, and volatile flavor compounds of tomato juice–skim milk mixtures fermented by Lactobacillus plantarum ST-III

Kun Wang,Chengjie Ma,Guangyu Gong,Chao Chang 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.4

This study evaluated the influence of tomatojuice enriched with the probiotic strain Lactobacillusplantarum ST-III on the flavor and health-promotingeffects of fermented skim milk. Fermentation parameters,such as titratable acidity, viable cell counts, antioxidantactivity, and volatile components, were examined. Theviable bacterial cell counts of 40% tomato juice sampleswere significantly higher than those in the control group,peaking at 1.09 9 109 CFU/mL after 48 h, and the titratableacidity was increased by 2.76-fold versus the controlvalue. The antioxidant ability of fermented milk was correlatedwith the tomato juice content in addition to fermentationtime in the 2,2-diphenyl-1-picrylhydrazyl andferric reducing/antioxidant power assays; for these methods,the scavenging activities of 40% samples were 1.18-and 1.28-fold higher than the control values, respectively,at 24 h. Moreover, abundant flavor components, especiallyaldehydes, were detected after the addition of L. plantarumST-III-supplemented tomato juice.

A polymeric composite protective layer for stable Li metal anodes

Guo Suogang,Wang Li,Jin Yuhong,Piao Nan,Chen Zonghai,Tian Guangyu,Li Jiangang,Zhao Chenchen,He Xiangming 나노기술연구협의회 2020 Nano Convergence Vol.7 No.21

Lithium (Li) metal is a promising anode for high-performance secondary lithium batteries with high energy density due to its highest theoretical specific capacity and lowest electrochemical potential among anode materials. However, the dendritic growth and detrimental reactions with electrolyte during Li plating raise safety concerns and lead to premature failure. Herein, we report that a homogeneous nanocomposite protective layer, prepared by uniformly dispersing ­AlPO 4 nanoparticles into the vinylidene fluoride-co-hexafluoropropylene matrix, can effectively prevent dendrite growth and lead to superior cycling performance due to synergistic influence of homogeneous Li plating and electronic insulation of polymeric layer. The results reveal that the protected Li anode is able to sustain repeated Li plating/stripping for > 750 cycles under a high current density of 3 mA cm −2 and a renders a practical specific capacity of 2 mAh cm −2 . Moreover, full-cell Li-ion battery is constructed by using ­LiFePO 4 and protected Li as a cathode and anode, respectively, rendering a stable capacity after 400 charge/discharge cycles. The current work presents a promising approach to stabilize Li metal anodes for next-generation Li secondary batteries.