업사이클 데님 디자인의 표현 방법 분석을 통한 3D 디지털 업사이클 데님 패션 디자인

천탠이(Tianyi Chen),이연희(Younhee Lee) 한국복식학회 2022 服飾 Vol.72 No.4

디지털 클로딩 기술 기반 가상착의 업사이클링 패션디자인

천탠이 ( Tianyi Chen ),양은경 ( Eun Kyoung Yang ),이연희 ( Younhee Lee ) 복식문화학회 2021 服飾文化硏究 Vol.29 No.3

The purpose of this study is to develop up-cycling fashion design methods centered on discarded denim material for the study of original up-cycling design methods. Up-cycling fashion design work was developed using digital clothing technology. This is a recent hot topic among sustainable fashion design methods. Up-cycling fashion design expression methods (categorized as dismantlement, collages, dépaysement, grafting, weaving, and tearing) were centered on design methods. These methods create various three-dimensional modeling effects in planar forms, whereby five pieces can be applied to the fabric and digitally produced. The results are as follows: First, the use of discarded denim fabric for the development of up-cycling fashion design pieces enabled the recycling of existing resources, provided solutions to environmental pollution problems, and provided expansion opportunities for design processes for sustainable fashion products that expand the design value of denim products and their utility. Second, new eco-friendly fashion designs that attempt to achieve diversity in modern fashion trends could be presented through formative contemporary fashion produced by up-cycling work products. Third, up-cycling fashion design work is expected to provide opportunities for eco-friendly fashion design methods. This will expand the value of sustainable fashion design by recycling simple waste materials through the use of three-dimensional digital clothing technology and further through the presentation of expanded life cycles that extend product planning, production, and life cycles.

Improvement of FK506 Production by Selection of 4-Aminobutyric Acid-tolerant Mutant and Optimization of its Fermentation Using Response Surface Methodology

Tianyi Yang,Jiaojiao Li,Liangzhi Li,Haiyang Zhang,Jing Ma,Zhi Chen,Cuiying Hu,Xin Ju,Jiaolong Fu 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.6

Tacrolimus (FK506), a 23-membered polyketidemacrolide with immunosuppressant activity, can be produced byStreptomyces tsukubaensis. We studied a variety of mutant strainsof S. tsukubaensis for the microbial production of FK506. Thebest strain (CZ-19) was obtained from the parent strain LLZ-1 bynitrosoguanidine mutation and 4-Aminobutyric acid (FK506precursor structure analogs) adaption. In the shake-flask experiments,titer of FK506 by CZ-19 was 532.44 mg/L, increased by 65.13%compared to that of the parent strain. Through single factorexperiments and response surface methodology, we furtheroptimized the medium for improved FK506 production by CZ-19in shake flask culture. The optimal medium for enhanced FK506production was as follows: 17.19 g/L corn starch, 21.78 g/Lglucose, 8.06 g/L peptone, and 18.98 mg/L 4-aminobutyric acid. The predicted FK506 titer was 906.49 mg/L, and the experimentaldata confirmed the validity of the model. The present studydemonstrates that S. tsukubaensis CZ-19 is a promising strain forindustrial production of FK506.

Improvement of FK506 Production by Selection of 4-Aminobutyric Acid-tolerant Mutant and Optimization of its Fermentation Using Response Surface Methodology

Yang, Tianyi,Li, Jiaojiao,Li, Liangzhi,Zhang, Haiyang,Ma, Jing,Chen, Zhi,Hu, Cuiying,Ju, Xin,Fu, Jiaolong 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.6

Tacrolimus (FK506), a 23-membered polyketide macrolide with immunosuppressant activity, can be produced by Streptomyces tsukubaensis. We studied a variety of mutant strains of S. tsukubaensis for the microbial production of FK506. The best strain (CZ-19) was obtained from the parent strain LLZ-1 by nitrosoguanidine mutation and 4-Aminobutyric acid (FK506 precursor structure analogs) adaption. In the shake-flask experiments, titer of FK506 by CZ-19 was 532.44 mg/L, increased by 65.13% compared to that of the parent strain. Through single factor experiments and response surface methodology, we further optimized the medium for improved FK506 production by CZ-19 in shake flask culture. The optimal medium for enhanced FK506 production was as follows: 17.19 g/L corn starch, 21.78 g/L glucose, 8.06 g/L peptone, and 18.98 mg/L 4-aminobutyric acid. The predicted FK506 titer was 906.49 mg/L, and the experimental data confirmed the validity of the model. The present study demonstrates that S. tsukubaensis CZ-19 is a promising strain for industrial production of FK506.

Exploiting the Reversibility of GTBP1 Catalyzed One-pot Reactions for the Synergistical Synthesis of Ponasterone A and Phenolic Glycosides

Yuqiang Li,Bingfeng Li,Tianyi Chen,Bin Wu,Jianlin Chu,Bingfang He 한국생물공학회 2021 Biotechnology and Bioprocess Engineering Vol.26 No.3

In the process of glycosyltransferase-catalyzed transglycosylation, the synthesis of uridine diphosphate sugars is generally thermodynamically disfavored. This study found that GTBP1 from Bacillus pumilus BF1 displayed the potential to reversely synthesize uridine diphosphate glucose (UDPG, UDP-glucose), which catalyzed the deglycosylation of ponasteroside A and the transglycosylation of phenolic compounds in one-pot reaction. Sequence alignment and phylogenetic tree analysis of GTBP1 and other GTs with reversible glycosylation ability were also implemented. Using solvent engineering strategy, the reaction time in water-organic biphasic was shortened and the conversion was improved. The final conversion of ponasterone A was reached 93.4%, and the final yield of ferulic acid glycoside was 92.7%. Using the fed-batch technology with the coupled reaction, the cumulative product of ponasterone A was about 1.97 g/L, and the level of produced ferulic acid glycoside was about 1.52 g/L. The substrate specificity of the GTBP1 was also confirmed. It implies the diversity of GTBP1's ability to construct UDP cycles.

3D-Distortion Based Rate Distortion Optimization for Video-Based Point Cloud Compression

Yihao Fu,Liquan Shen,Tianyi Chen 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.2

The state-of-the-art video-based point cloud compression(V-PCC) has a high efficiency of compressing 3D point cloud by projecting points onto 2D images. These images are then padded and compressed by High-Efficiency Video Coding(HEVC). Pixels in padded 2D images are classified into three groups including origin pixels, padded pixels and unoccupied pixels. Origin pixels are generated from projection of 3D point cloud. Padded pixels and unoccupied pixels are generated by copying values from origin pixels during image padding. For padded pixels, they are reconstructed to 3D space during geometry reconstruction as well as origin pixels. For unoccupied pixels, they are not reconstructed. The rate distortion optimization(RDO) used in HEVC is mainly aimed at keeping the balance between video distortion and video bitrates. However, traditional RDO is unreliable for padded pixels and unoccupied pixels, which leads to significant waste of bits in geometry reconstruction. In this paper, we propose a new RDO scheme which takes 3D-Distortion into account instead of traditional video distortion for padded pixels and unoccupied pixels. Firstly, these pixels are classified based on the occupancy map. Secondly, different strategies are applied to these pixels to calculate their 3D-Distortions. Finally, the obtained 3D-Distortions replace the sum square error(SSE) during the full RDO process in intra prediction and inter prediction. The proposed method is applied to geometry frames. Experimental results show that the proposed algorithm achieves an average of 31.41% and 6.14% bitrate saving for D1 metric in Random Access setting and All Intra setting on geometry videos compared with V-PCC anchor.

Incremental fuzzy clustering based on a fuzzy scatter matrix

Yongli Liu,Hengda Wang,Tianyi Duan,Jingli Chen,Hao Chao 한국정보처리학회 2019 Journal of information processing systems Vol.15 No.2

For clustering large-scale data, which cannot be loaded into memory entirely, incremental clustering algorithmsare very popular. Usually, these algorithms only concern the within-cluster compactness and ignore thebetween-cluster separation. In this paper, we propose two incremental fuzzy compactness and separation (FCS)clustering algorithms, Single-Pass FCS (SPFCS) and Online FCS (OFCS), based on a fuzzy scatter matrix. Firstly, we introduce two incremental clustering methods called single-pass and online fuzzy C-meansalgorithms. Then, we combine these two methods separately with the weighted fuzzy C-means algorithm, sothat they can be applied to the FCS algorithm. Afterwards, we optimize the within-cluster matrix and betweenclustermatrix simultaneously to obtain the minimum within-cluster distance and maximum between-clusterdistance. Finally, large-scale datasets can be well clustered within limited memory. We implemented experimentson some artificial datasets and real datasets separately. And experimental results show that, compared withSPFCM and OFCM, our SPFCS and OFCS are more robust to the value of fuzzy index m and noise.

Tectono-magmatic evolution of the Mesozoic granodiorite and their diorite enclaves in Shulan Area, Jilin, China

Mengmeng Li,Jingdang Liu,Tianyi Liang,Chen Li,Dejun Bao 한국지질과학협의회 2022 Geosciences Journal Vol.26 No.1

The Mesozoic granodiorite and their diorite enclaves in the Shulan area have been investigated to understand the petrographic characteristics and elemental geochemistry and to further interpret the petrogenesis and paleotectonic environment. The petrography, mineral component, zircon U-Pb age, and major and trace element contents of 9 granodiorite host rock samples and 9 diorite enclave samples were analyzed. Results show host rock and the enclave both present of medium-fine subhedral and porphyritic. The main rock-forming minerals of host rocks are plagioclase (57–60%), quartz (25–30%), and K-feldspar (6–13%), whereas the main rock-forming minerals of enclaves are plagioclase (65–83%), amphibole (3–20%), and biotite (5–25%). Zircon U-Pb dating results show that the weighted-mean 206Pb/238U ages of the granodiorite host rock and the diorite enclave are 168.1 ± 1.6 Ma and 181.0 ± 1.0 Ma, respectively. The SiO2 contents of the host rocks and enclaves are 61.95–64.86% and 51.12–59.32%, respectively. Their K2O/Na2O ratios are 0.51–1.24 and 0.41–1.02; aluminum saturation index A/CNK [Al2O3/(CaO + Na2O + K2O) molar ratio] are between 0.80–1.14 and 0.70–0.98 and A/NK [Al2O3/(Na2O + K2O) molar ratio] are 1.48–1.97 and 1.47–2.11, indicating a medium-high-K calc-alkaline series and a metaluminous series. The chondrite-normalized rare earth element (REE) patterns of both host rock and enclave samples show a right-dip model, but the Eu ratios of the host rock samples show weak negative anomalies, whereas the Eu ratios of the enclave samples show distinctive negative anomalies. The δEu [δEu = EuN/sqrt(SmN × GdN)] averages of both host rock and enclave samples are 0.75 and 0.63, respectively. The primary mantle normalized trace element patterns shows the enrichment of Rb, Th, U, La, Zr, Hf and Li and the depletion of Nb and Sm in the granodiorite host rocks, whereas enriched Rb, U, La, Pr, Nd, Zr, Hf, and Li and depleting Ba, Nb, Sr, Sm, and Eu are presented in the diorite enclaves. The REE, trace element patterns and the other geochemical indices indicate both granodiorite and diorite were derived from partial melting of pre-existent basaltic materials with a minor contribution of mantle materials. Host rocks and enclaves were formed in the same subduction-related paleotectonic environment, but in different stages of magma evolution. The subduction triggered the delamination of the lithosphere, causing upwelling of the asthenosphere and partial melting of the crust, forming the magmatic precursors of both kinds of rocks.

Incremental Fuzzy Clustering Based on a Fuzzy Scatter Matrix

Liu, Yongli,Wang, Hengda,Duan, Tianyi,Chen, Jingli,Chao, Hao Korea Information Processing Society 2019 Journal of information processing systems Vol.15 No.2

For clustering large-scale data, which cannot be loaded into memory entirely, incremental clustering algorithms are very popular. Usually, these algorithms only concern the within-cluster compactness and ignore the between-cluster separation. In this paper, we propose two incremental fuzzy compactness and separation (FCS) clustering algorithms, Single-Pass FCS (SPFCS) and Online FCS (OFCS), based on a fuzzy scatter matrix. Firstly, we introduce two incremental clustering methods called single-pass and online fuzzy C-means algorithms. Then, we combine these two methods separately with the weighted fuzzy C-means algorithm, so that they can be applied to the FCS algorithm. Afterwards, we optimize the within-cluster matrix and betweencluster matrix simultaneously to obtain the minimum within-cluster distance and maximum between-cluster distance. Finally, large-scale datasets can be well clustered within limited memory. We implemented experiments on some artificial datasets and real datasets separately. And experimental results show that, compared with SPFCM and OFCM, our SPFCS and OFCS are more robust to the value of fuzzy index m and noise.

Outcomes of Anti-CD19 CAR-T Treatment of Pediatric B-ALL with Bone Marrow and Extramedullary Relapse

Xinyu Wan,Xiaomin Yang,Fan Yang,Tianyi Wang,Lixia Ding,Lili Song,Yan Miao,Xiang Wang,Yani Ma,Chengjuan Luo,Jingyan Tang,Longjun Gu,Jing Chen,Yanjing Tang,Jun Lu,Benshang Li 대한암학회 2022 Cancer Research and Treatment Vol.54 No.3

PurposeAnti-CD19 chimeric antigen receptor T-cell immunotherapy (19CAR-T) has achieved impressive clinical results in adult and pediatric relapsed/refractory (r/r) B-lineage acute lymphoblastic leukemia (B-ALL). However, the application and effect of CAR-T therapy in B-ALL patients with extramedullary relapse are rarely issued even disqualified in some clinical trials. Here, we examined the efficacy of 19CAR-T in patients with both bone marrow and extramedullary involvement.Materials and MethodsCAR-T cells were generated by transfection of primary human T lymphocytes with a lentiviral vector expressing anti-CD19 single chain antibody fragments (scFvs) with the cytoplasmic domains of 4-1BB and CD3ζ, and used to infuse patients diagnosed as having r/r B-ALL with extramedullary origination. Clinical responses were evaluated by the use of bone marrow aspiration, imaging, and flow cytometry. ResultsEight patients received 19CAR-T infusion and all attained complete remission (CR). Only one patient was bridged to hematopoietic stem cell transplantation (HSCT). Although three patients relapsed after infusion, they received 19/22CAR-T infusion sequentially and attained a second remission. To date, five patients are in continuous CR and all eight patients are still alive. The mean follow-up time was 21.9 months, while the 24-month estimated event-free survival is 51.4%. Conclusion19CAR-T therapy can lead to clinical remission for extramedullary relapsed pediatric B-ALL patients. However, the problem of CD19+ relapses after CAR-T remained to be solved. For patients relapsing after CAR-T, a second CAR-T therapy creates another opportunity for remission for subsequent HSCT.