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이수태,기해진,정순택,박양균 木浦大學校 工業技術硏究所 2000 工業技術硏究誌 Vol.10 No.-
Frozen dough of two flour, Tazo and Tazo-S, and two thawing, room and cold temperature, were determined to qualified bread quality. For best bread quality from frozen doughs, very strong flour should be used. Frozen doughs are increasingly being produced in the baking industry even though they generally provide bread with lower loaf volume than dose unfrozen fresh dough. Several investigators have reported that the major changes in doughs that have been frozen are related to yeast. During the dough fermentation, yeast produces carbon dioxide and flavor compounds. Loaf volume decreased markedly with freezing and thawing, and gradually during frozen storage.
Idiopathic Vestibular Disease in a Beagle Dog: Clinical Findings and Outcome
Byeong-Teck Kang,Dong-In Jung,Chul Park,Su-Hyun Gu,Hyo-Won Jeon,박희명 한국임상수의학회 2006 한국임상수의학회지 Vol.23 No.3
10-year-old, intact female Beagle dog was presented for examination of acute onset of right-sided headtilt and moderate ataxia. Clinical signs were acutely presented 12 days ago and had been progressively alleviated untilthe admision day. The dog was bright, alert, and responsive. On neurological examinations, mild head tilt to the rightand mild ataxia were noted, thus vestibular disorders were suspected. Central vestibular disease was ruled out basedon the clinical signs, magnetic resonance imaging (MRI), and cerebrospinal fluid (CSF) analysis. Otoscopic examinationshowed that the tympanic membranes were intact and normal in appearance. On radiographic and MR examinations,abnormalities were not found in the tympanic bulla and the petrous portion of the temporal bone. Hypothyroidismwas ruled out by thyroid-stimulation hormone (TSH) stimulation test. Clinical signs were completely disappeared at2 weeks after discharge without any therapy. Thus, the dog was definitively diagnosed as idiopathic vestibular diseasebased on the clinical signs, excluding other causes of vestibular dysfunction, and the alleviation of clinical signs withtime.
Kang, Byeong-Teck,Jang, Dong-Pyo,Gu, Su-Hyun,Lee, Jong-Hwan,Jung, Dong-In,Lim, Chae-Young,Kim, Ha-Jung,Kim, Young-Bo,Kim, Hyung-Joong,Woo, Eung-Je,Cho, Zang-Hee,Park, Hee-Myung American Association for Laboratory Animal Science 2009 Comparative medicine Vol.59 No.5
<P>The purpose of this study was to evaluate the diagnostic value of magnetic resonance imaging (MRI) and assess the correlation between the volume of the ischemic lesion and neurobehavioral status during the subacute stage of ischemic stroke. Ischemic stroke was induced in 6 healthy laboratory beagles through permanent occlusion of the middle cerebral artery (MCAO). T2-weighted and fluid-attenuated inversion recovery (FLAIR) imaging, diffusion-weighted imaging (DWI), measurement of the apparent diffusion coefficient (ADC) ratio, and neurobehavioral evaluation were performed 3 times serially by using a 1.5-T MR system: before and 3 and 10 d after MCAO. Ischemic lesions demonstrated T2 hyperintensity, FLAIR hyperintensity, and DWI hyperintensity. The ADC ratio was decreased initially but then was increased at 10 d after MCAO. Ischemic lesion volumes on T2-weighted and FLAIR imaging were not significantly different from those on DWI. The lesion volume and neurobehavioral score showed strong correlation. Our results suggest that conventional MRI may be a reliable diagnostic tool during the subacute stage of canine ischemic stroke.</P>
KANG, Byeong-Teck,PARK, Chul,YOO, Jong-Hyun,GU, Su-Hyun,JANG, Dong-Pyo,KIM, Young-Bo,WOO, Eung-Je,KIM, Dae-Young,CHO, Zang-Hee,PARK, Hee-Myung Japanese Society of Veterinary Science 2009 The Journal of veterinary medical science Vol.71 No.10
<P>A 10-year-old, neutered male, Maltese dog presented with a three week history of intention tremor, right hind limb rigidity, poor coordination, and occasional circling to the left. On magnetic resonance imaging (MRI) of the brain, a mass was identified in the right occipital lobe and cerebellum. Three weeks after the initial MRI scan, we performed an <SUP>18</SUP>F-fluorodeoxyglucose positron emission tomography (FDG-PET) of the brain. The FDG-PET demonstrated areas of hypermetabolism in the right occipital lobe, cerebellum, pons, and medulla oblongata. When the standardized uptake value was calculated, the hypermetabolic lesion was higher than the gray matter values. The anatomical location of the hypermetabolic lesion was more precisely identified by the PET-MRI fusion images. The dog was definitively diagnosed as a primary histiocytic sarcoma of the brain. This is the first report of PET findings of an intracranial histiocytic sarcoma in a dog.</P>
Kang, Byeong-Teck,Jang, Dong-Pyo,Gu, Su-Hyun,Kim, Young-Bo,Lim, Chae-Young,Lee, Jong-Hwan,Woo, Eung-Je,Cho, Zang-Hee,Park, Hee-Myung American Association for Laboratory Animal Science 2009 Comparative medicine Vol.59 No.1
<P>The purpose of this study was to evaluate the potential efficacy of 3-dimensional time-of-flight magnetic resonance angiography (TOF-MRA) to validate a canine ischemic stroke model. Ischemic stroke was induced through permanent middle cerebral artery occlusion (MCAO) in 5 healthy Beagle dogs. T2-turbo spin echo images and TOF-MRA were obtained with a 1.5-T magnetic resonance system before and 3 and 10 d after MCAO. In 3 dogs, angiograms of the brain obtained at 3 d after MCAO showed complete occlusion of the MCA; in addition, T2 hyperintensities were present unilaterally in the striatocapsular and cerebral cortex lesions. Partial occlusion of the proximal part of the MCA was identified in the 2 remaining dogs, with T2 hyperintensities present only in the striatocapsular lesions. The occluded sites were confirmed at necropsy. The results of this study demonstrate the potential of TOF-MRA to provide a detailed description of intracranial arteries and aid in the evaluation of flow impairment in a canine MCAO model.</P>
Kang, Byeong-Teck,Kim, Seung-Gon,Lim, Chae-Young,Gu, Su-Hyun,Jang, Dong-Pyo,Kim, Young-Bo,Kim, Dae-Young,Woo, Eung-Je,Cho, Zang-Hee,Park, Hee-Myung Canadian Veterinary Medical Association 2010 The Canadian veterinary journal Vol.51 No.9
<P>This study characterized the [(18)F]2-deoxy-2-fluoro-D-glucose positron emission tomography (FDG-PET) findings of encephalitis in dogs and assessed the role of FDG-PET in the diagnosis of meningoencephalitis. The medical records, magnetic resonance (MR), and FDG-PET images of 3 dogs with necrotizing meningoencephalitis (NME), 1 dog with granulomatous meningoencephalitis (GME), and 1 dog with meningoencephalitis of unknown etiology (MUE) were reviewed. On the FDG-PET, glucose hypometabolism was identified in the dog with NME, whereas hypermetabolism was noted in the dog with GME. The T2-weighted images (WI) and fluid attenuated inversion recovery (FLAIR) images were characterized by hyperintensity, whereas the signal intensity of the lesions on the T1-WI images was variable. The metabolic changes on the brain FDG-PET corresponded well to the hyper- and hypointense lesions seen on the MR imaging. This type of tomography (FDG-PET) aided in the differentiation of different types of inflammatory meningoencephalitis when the metabolic data was combined with clinical and MR findings.</P>
Kang, Byeong-Teck,Park, Chul,Jung, Dong-In,Yoo, Jong-Hyun,Kim, Ju-Won,Gu, Su-Hyun,Jeon, Hyo-Won,Kim, Jung-Hyun,Woo, Eung-Je,Park, Hee-Myung The Korean Society of Veterinary Science 2007 大韓獸醫學會誌 Vol.47 No.2
A 14-month-old, neutered female Miniature Pinscher was referred due to severe renal failure. The dog was treated with hysterotomy and followed by ovariohysterectomy (OHE) 6 days before the presentation. Excretory urographic and ultrasonographic studies revealed bilateral hydroureter and hydronephrosis. Postmortem necropsy revealed that ligatures were placed around the caudal portion of bilateral ureters in front of entrance into the bladder. This case shows that identifying and protecting the ureters are important during hysterotomy with OHE as well as OHE.
Kang, Byeong-Teck,Jang, Dong-Pyo,Lee, Jong-Hwan,Jung, Dong-In,Gu, Su-Hyun,Lim, Chae-Young,Kim, Young-Bo,Quan, Fu-Shi,Kim, Hyung-Joong,Woo, Eung-Je,Cho, Zang-Hee,Park, Hee-Myung Elsevier 2009 Research in veterinary science Vol.87 No.2
<P><B>Abstract</B></P><P>Proton magnetic resonance spectroscopy (<SUP>1</SUP>H MRS) provides <I>in vivo</I> biochemical information on tissue metabolites. The purpose of this study was to investigate the serial metabolic changes of <SUP>1</SUP>H MRS in the cerebrum of ischemic dogs. An ischemic stroke was induced in five health laboratory beagle dogs by permanent middle cerebral artery occlusion using a silicone plug. <SUP>1</SUP>H MRS was serially performed three times with a 1.5-T MR system: before, three days after and 10days after the stroke. Immunohistochemical staining was performed to determine the expression of neuronal nuclei (NeuN) and glial fibrillary acidic protein (GFAP) at both the ipsilateral and contralateral cerebral cortex. Reduced levels of <I>N</I>-acetyl-asparate (<I>p</I><0.05), choline (Cho), creatine (Cr) and myo-inositol (mI), and a marked increase in the lactate (Lac) level (<I>p</I><0.01) were found at three days after the stroke. At 10days after the stroke, the levels of Lac significantly increased (<I>p</I><0.01); however, the other metabolites were partially elevated. The changes of Cr, Cho and mI were not statistically significant (<I>p</I>>0.05) when the before and after stroke values were compared. There was a significant loss of NeuN and GFAP immunoreactivity at the ischemic core. <SUP>1</SUP>H MRS may be to a useful diagnostic tool for the evaluation of ischemic stroke in dogs.</P>
Hee-Myung Park,Byeong-Teck Kang,이종환,Dong-In Jung,Chul Park,Su-Hyun Gu,Hyo-Won Jeon,장동표,Chae-Young Lim,Fu-Shi Quan,Young-Bo Kim,Zang-Hee Cho,Eung-Je Woo 대한수의학회 2007 Journal of Veterinary Science Vol.8 No.4
The aim of the present study was to assess the clinical and histopathological findings in a canine model of ischemic stroke. Cerebral ischemic stroke was induced by middle cerebral artery occlusion in four healthy beagle dogs using silicone plugs. They showed neurological signs of forebrain dysfunction such as reduced responsiveness, head turning, circling, postural reaction deficits, perceptual deficits, and hemianopsia. These signs gradually regressed within 4 weeks without therapy. On magnetic resonance imaging, T2 hyperintensity and T1 hypointensity were found in the cerebral cortex and basal ganglia. These lesions were well-defined and sharply demarcated from adjacent brain parenchyma with a homogenous appearance. No abnormalities of the cerebrospinal fluid were observed. At necropsy, atrophic and necrotic lesions were observed in the cerebral cortex. The cerebral cortex, basal ganglia, and thalamus were partially unstained with triphenyl- tetrazolium chloride. Histopathologically, typical features of infarction were identified in cortical and thalamic lesions. This study demonstrates that our canine model resembles the conditions of real stroke patients.