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Park, Sang Hee,Choi, Eunju,Kim, Sunggyu,Kim, Dong Sam,Kim, Ji Hyeon,Chang, SeokGu,Choi, Jae Seok,Park, Kyung Ja,Roh, Kyung-Baeg,Lee, Jongsung,Yoo, Byong Chul,Cho, Jae Youl MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.9
<P>Loliolide is a monoterpenoid hydroxylactone found in many algae, including fresh water green algae, <I>Prasiola japonica</I>. To date, loliolide and compounds in <I>P. japonica</I> have not been studied systematically with respect to skin pharmacology. In this study, we investigated oxidative stress-protective and anti-melanogenic effects of loliolide and <I>P. japonica</I> ethanol extract (Pj-EE), known to contain loliolide, in human keratinocyte (HaCaT) cells and mouse melanoma (B16F10) cells. Loliolide suppressed the transcription of genes encoding matrix metalloproteinases (MMPS), which were induced in HaCaT cells by hydrogen peroxide (H<SUB>2</SUB>O<SUB>2</SUB>) treatment. Loliolide and Pj-EE not only reduced the melanin secretion and content in B16F10 cells but also increased the expression of the antioxidant proteins nuclear factor (erythroid-derived 2)-like 2 (NRF2) and heme oxygenase-1 (HO-1) in HaCaT cells subjected to H<SUB>2</SUB>O<SUB>2</SUB> treatment. Furthermore, loliolide and Pj-EE decreased expression of the anti-melanogenic protein microphthalmia-associated transcription factor (MITF) and tyrosinase in B16F10 cells subjected to α-melanocyte-stimulating hormone (α-MSH) treatment. Our findings demonstrate that loliolide and Pj-EE have antioxidant and anti-melanogenic effects on skin.</P>
Multi-routing based Mobility Management with an Optimized Security Network
Sunggyu Kim,Byungjoo Park 대한전자공학회 2019 IEIE Transactions on Smart Processing & Computing Vol.8 No.4
Recently, there has been a drastic increase in the risk of personal information leakage brought about by inconsistencies in network security triggered by cyber-attacks. The persistent surge of internet users is paralleled by the demands for wireless services, which have become more susceptible to cyber-attacks, compared with wired services. Thus, a high level for quality of service is essential when providing wireless services to users. In addition, a reduced handover delay when a mobile node moves between network access points must be provided by wireless network systems. However, with a stronger security system implemented in a wireless environment, it follows that there will be a significant increase in handover delay. It simply means that current wireless network systems are unable to provide the desired QoS for the wireless services demanded by Internet users. Consequently, various security and QoS enhancement protocols have been studied and developed, but a lot more challenges need to be addressed. This paper proposes a robust security scheme to support fast handovers for mobility management protocols over Internet Protocol version 6 (IPv6) through utilization of an exchange key.
Sunggyu Lee(이성규),Tae-Jin Park(박태진),Kyungho Choi(최경호),Hyo-Bang Moon(문효방) 환경독성보건학회 2021 한국독성학회 심포지움 및 학술발표회 Vol.2021 No.5
Synthetic musk compounds (SMCs) are typical anthropogenic organic contaminants used as additives in many consumer products. SMCs could enter into the aquatic environment through effluents of wastewater treatment plants (WWTPs). Several studies reported that acute and chronic toxicity to aquatic organisms. In this study, surface water, sediment, and biota samples were collected from four major rivers of Korea in 2020, and were determined for 12 SMCs using a gas chromatography coupled to tandem mass spectrometer. Among analyzed SMCs, HHCB, DPMI, MK, and AHTN were detected in water samples. Mean concentrations of SMCs (ΣSMC) was 229, 99.8, 85.6, and 90.5 ng/L in Han, Gum, Yeongsan, and Nakdong Rivers, respectively. The major SMCs in Korean rivers was HHCB followed by MK, DPMI, and AHTN. The concentrations of HHCB and AHTN measured in our study were within the ranges of those reported for other countries. Seasonally, ΣSMC was the highest in winter. The next highest concentration was spring, autumn, and summer. These seasonal variations of SMCs concentrations are related to precipitation and temperature of each season. Similar with the results in water, HHCB (mean: 6.94 ng/g dw for sediment and 1999 ng/g lw for biota), AHTN (1.38 ng/g dw and 311 ng/g lw), and MK (0.04 ng/g dw and 245 ng/g lw) show at detectable concentrations in sediment and biota samples. An ecological risks of SMCs to aquatic organisms were assessed by comparing with PNEC value. The results showed that SMCs were negligible to pose an ecological risk to aquatic organisms in Korean rivers.
Passive Bypass Using Anthron Tube in Adult Living Donor Liver Transplantation
SungGyu Lee,Shin Hwang,KiHoon Kim,ChulSoo Ahn,KwangMin Park,YoungJoo Lee,DeokBog Moon,ChongWoo Chu,HyunSeong Yang,SungHoon Cho,KiBong Oh,TaeYong Ha,KiWon Song,YunSik Yu,PyungChul Min 대한외과학회 2002 대한외과학회 학술대회 초록집 Vol.2002 No.10
박성규,백세민,정성훈 大韓成形外科學會 1995 Archives of Plastic Surgery Vol.22 No.1
In the treatment of mandibular angle fracture, the accurate reduction and secure immobilization are essential especially due to different direction of power of the anterior and posterior muscle group of the mandible. For immobilization, various kinds of internal fixation technique have been deviced, but they have its own limitations. The author performed the screw and wire fixation technique through transoral incision and with percutaneous fixation in 7 cases. Its main advantages are rigid fixation without external approach and less possibility of error due to simultaneous reduction and fixation with wiring. Besides, this technique is very simple and easy technique if accustomed to percutaneous fixation technique.
문화관광지원 방문자의 만족과정에서 해설의 역할 - 상황적 관점
박동진(Park Tongjin),조성한(Jo Sunghan),오승규(Oh Sunggyu),김정희(Kim Jeonghee) 한국소비문화학회 2008 소비문화연구 Vol.11 No.3
방문자는 해설을 통해 문화관광자원을 보다 잘 이해하고 방문과정에서 더 높은 만족을 경험할 수 있다. 그러나 해설은 노력과 비용이 수반되는 활동임에도 불구하고 해설의 영향력을 상황별로 분석한 연구는 드문 실정이다. 본 연구는 첫째, 문화관광자원 방문자의 전반적 만족과정을 이해하는데 ACSI모형을 적용할 수 있는가? 둘째, 해설이 행해진 경우와 그렇지 않은 경우 해설의 영향력은 어떻게 달라지는가? 셋째, 상황변수로 관여도를 도입하고 관여도 고ㆍ저 수준과 해설유무별 4가지 상황에서 해설의 영향력을 비교평가하였다. 연구결과 문화관광자원 방문자의 만족과정은 고객만족지수모형(ACSI)을 적용할 수 있고, 방문자 만족과정은 해설유무보다 관여도 상황에 더 많은 영향을 받고, 관여도 수준이 높은 방문자들에게 해설을 행하는 것이 만족을 가장 높일 수 있음을 발견하였다. 본 연구의 결과는 문화관광자원 방문자의 만족을 높일 전략을 수립하는데 도움을 줄 것이다. Visitors are likely to understand and be satisfied with a tour that includes interpretation. Incorporating interpretation in tourism requires great costs, but few efforts have been made to find the specific situations for this service to be really effective. Our research is analyzed with the following issues. First, is it possible to apply the ACSI model to understand the overall satisfaction process of the Cultural Tourism Visitors? Second, how does it differ between the tour with and without interpretation services? Third, the involvement is introduced as the situational variable, and the role of the interpretation service is assessed in four situations. As the results, the ACSI model is applicable to understand the overall satisfaction process of the Cultural Tourism Visitors. Also, it shows that the higher the visitors" involvement is, the more effective to achieve satisfaction. These results will be helpful in establishing several strategies to increase visitors" satisfaction.
Lee, Sunggyu,Kim, Sunmi,Park, Jeongim,Kim, Hai-Joong,Choi, Gyuyeon,Choi, Sooran,Kim, Sungjoo,Kim, Su Young,Kim, Sungkyoon,Choi, Kyungho,Moon, Hyo-Bang Elsevier 2018 Science of the Total Environment Vol.612 No.-
<P><B>Abstract</B></P> <P>Breastfeeding is an important exposure pathway to perfluoroalkyl substances (PFASs) for newborn infants. Nevertheless, reports are limited on the occurrence and time-course of PFASs in breast milk, and most studies have focused on the analysis of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA). In this study, 16 PFASs were analyzed in breast milk samples (<I>n</I> =293) collected from 128 mothers in Korea during various lactation periods to assess maternal exposure levels, contamination profiles, time-course variations, and infant health risks. The total concentrations of PFASs (ΣPFAS) ranged from 31.7 to 1004 (median: 188) ng/L, which was within the ranges recently reported for Asian and European populations. After a month of nursing, the concentrations of PFOS, PFOA, perfluorononanoic acid (PFNA), and ΣPFAS significantly increased. This could be due to changes in the dietary and behavior patterns of the mothers after the first month of lactation. The concentrations of PFOS and PFOA were significantly correlated with maternal age, body mass index, and parity. Certain types of diet (e.g. consuming snacks and milk) and eating-out frequency were significantly associated with increasing levels of PFAS. Significant correlations and similar time-course trends were found between PFASs and PCBs/DDTs, implying similar exposure sources and biokinetics for these contaminants. The estimated daily intakes of PFOS and PFOA via the consumption of breast milk were below the tolerable daily intakes for infants suggested by the European Food Safety Authority (EFSA).</P> <P><B>Highlights</B></P> <P> <UL> <LI> PFOS, PFOA, PFUnDA, and PFNA were the predominant compounds in breast milk. </LI> <LI> Concentrations of PFASs were significantly correlated with maternal age, BMI, and parity. </LI> <LI> Increased levels of PFASs were found in breast milk after the first month of nursing. </LI> <LI> Snack consumption and frequency of eating-out were significantly associated with increased PFAS levels. </LI> <LI> The infant exposure levels of PFOS and PFOA via breast milk were lower than the TDI. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>