Adaptive Neural Tracking Control for Uncertain Switched Nonlinear Non-lower Triangular System with Disturbances and Dead-zone Input

Rui-Bing Li,Xiao-Mei Wang,Xiao-Mei Liu,Ben Niu,Dong Yang 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.6

This work investigates the adaptive neural tracking control problem for a class of uncertain switched nonlinear non-lower triangular systems with disturbances and dead-zone input. First, radial basis function (RBF) neural networks (NNs) serve as a flexible tool to approximate the unknown nonlinear functions. Then during the controller design, the dynamic surface control (DSC) method is used to avoid the issue of "explosion of complexity", and only one adaptive law is adopted to reduce the computational burden. What’s more, a few classical mathematical approaches are used to handle the design difficulties caused by dead-zone input, and the proposed controller guarantees the closed-loop system signals are semi-globally uniform ultimate boundedness (SGUUB). Finally, a simulation example is given to illustrate the availability of the proposed control scheme.

Influence of Amorphous and Silicon Steel on Performance of Permanent Magnet Synchronous Motors Used in Steering Pump of Electric Vehicles

Rui-fang Liu,Xin Ma,Jun-ci Cao,Shuang-xia Niu,Zhi-gang Wu 한국자기학회 2019 Journal of Magnetics Vol.24 No.2

Amorphous materials have the advantages of high permeability and low core losses. Their application in the motor can reduce the energy consumption and improve the efficiency. To investigate the advantage of amorphous materials on the performance of permanent magnet synchronous motors (PMSMs) at lower speed situation, three 1.5 kW motors used in steering pumps of electric vehicles are analyzed and compared. Two prototypes and the experimental platform are built. The experimental results indicate that the efficiency of the PMSM motor with amorphous materials increases by 1.4 % at 1200 rpm, which shows that amorphous materials can also improve the motor performance at lower speed. To further take advantage of amorphous materials, the particle swarm optimization algorithm is used to optimize the dimensions of amorphous motor and the efficiency is increased by 0.54 %.

Investigation of aerodynamic behaviour of a high-speed train on different railway infrastructure scenarios under crosswind

Jiqiang Niu,Yingchao Zhang,Zheng-Wei Chen,Rui Li,Huadong Yao 한국풍공학회 2022 Wind and Structures, An International Journal (WAS Vol.35 No.6

The aerodynamic behaviour of a CRH high-speed train under three infrastructure scenarios (flat ground, embankment, and viaduct) in the presence of a crosswind was simulated using a 1/8th scaled train model with three cars and the IDDES framework. The time-averaged and instantaneous flow field around the model were examined. The employed numerical algorithm was verified through a wind tunnel test, and the grid and timestep resolution analyses were conducted to ensure the reliability of the data. It was noted that the flow around the rail line was different under different infrastructure scenarios, especially in the case of the embankment, which degraded the aerodynamic performance of the train under the crosswind. The flow around the train on the flat ground and viaduct was different, although the aerodynamic performance of the train was similar in both cases. Moreover, the viaduct accidents were noted to have the most critical consequences, thereby requiring the most attention. The aerodynamic performance of the train on the windward track of the embankment under the crosswind was worse than that of the train on the leeward track. But for the other two infrastructure scenarios, the aerodynamic performance of the train on the windward track is relatively dangerous, which is mainly caused by the head car. These observations suggest that the aerodynamic behaviour of the train on an embankment under a crosswind must be carefully considered and that certain wind protection measures must be adopted around rail lines in windy areas.

Image Steganography via Fully Exploiting Modification Direction

Xuejing Niu,Meng Ma,Rui Tang,Zhaoxia Yin 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.5

Sulphonated Reduced Graphene Oxide: A High Performance Anode Material for Lithium Ion Battery

Haibo Li,Rui Niu,Sen Liang,Yulong Ma,Min Luo,Jin Li,Lijun He 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.4

In this work, the sulfonated reduced graphene oxide (SRGO) was synthesized and proposed as an enhanced anode material for lithium ion battery (LIB). The result shows that the SRGO has an improved battery performance (i.e., ~341.7 mAh/g and ~190.6 mAh/g corresponds to SRGO and RGO at the 100th cycle with a current density of 200 mA/g) and superior cycling stability compared with pristine reduced graphene oxide (RGO). These are attributed to the improved specific surface area (448.35 m2 /g) and conductivity (2.5 x 10-4 S/m). Further, the SRGO exhibits good rate capability and excellent energy density at various current densities ranging from 50 mAh/g to 2000 mAh/g, suggesting that SRGO could be a promising anode material for high capacity LIB.

Effect of Vitamin E Supplementation on Intestinal Barrier Function in Rats Exposed to High Altitude Hypoxia Environment

Chunlan Xu,Rui Sun,Xiangjin Qiao,Xiaoya Shang,Weining Niu,Yu Chao 대한약리학회 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.4

The study was conducted to investigate the role of vitamin E in the high altitude hypoxia-induceddamage to the intestinal barrier in rats. Sprague-Dawley rats were divided into control (Control), highaltitude hypoxia (HH), and high altitude hypoxia+ vitamin E (250 mg/kg BW*d) (HV) groups. Afterthe third day, the HH and HV groups were placed in a hypobaric chamber at a stimulated elevationof 7000 m for 5 days. The rats in the HV group were given vitamin E by gavage daily for 8 days. The other rats were given equal volume saline. The results showed that high altitude hypoxia causedthe enlargement of heart, liver, lung and kidney, and intestinal villi damage. Supplementation withvitamin E significantly alleviated hypoxia-caused damage to the main organs including intestine,increased the serum superoxide dismutase (SOD) (p< 0.05), diamino oxidase (DAO) (p< 0.01) levels,and decreased the serum levels of interleukin-2 (IL-2) (p< 0.01), interleukin-4 (IL-4) (p<0.001),interferon-gamma (IFN-γ) (p<0.01) and malondialdehyde (MDA) (p<0.001), and decreased the serumerythropoietin (EPO) activity (p<0.05). Administration of vitamin E significantly increased the S-IgA(p<0.001) in ileum and significantly improved the expression levels of occludin and IκBα, anddecreased the expression levels of hypoxia-inducible factor 1 alpha and 2 alpha (HIF-1α and HIF-2α),Toll-like receptors (TLR4), P-IκBα and nuclear factor-κB p65(NF-κB P65) in ileum compared to theHH group. This study suggested that vitamin E protectis from intestinal injury caused by high altitudehypoxia environment. These effects may be related to the HIF and TLR4/NF-κB signaling pathway.

Effect of Vitamin E Supplementation on Intestinal Barrier Function in Rats Exposed to High Altitude Hypoxia Environment

Xu, Chunlan,Sun, Rui,Qiao, Xiangjin,Xu, Cuicui,Shang, Xiaoya,Niu, Weining,Chao, Yu The Korean Society of Pharmacology 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.4

The study was conducted to investigate the role of vitamin E in the high altitude hypoxia-induced damage to the intestinal barrier in rats. Sprague-Dawley rats were divided into control (Control), high altitude hypoxia (HH), and high altitude hypoxia + vitamin E (250 mg/kg $BW^*d$) (HV) groups. After the third day, the HH and HV groups were placed in a hypobaric chamber at a stimulated elevation of 7000 m for 5 days. The rats in the HV group were given vitamin E by gavage daily for 8 days. The other rats were given equal volume saline. The results showed that high altitude hypoxia caused the enlargement of heart, liver, lung and kidney, and intestinal villi damage. Supplementation with vitamin E significantly alleviated hypoxia-caused damage to the main organs including intestine, increased the serum superoxide dismutase (SOD) (p< 0.05), diamino oxidase (DAO) (p< 0.01) levels, and decreased the serum levels of interleukin-2 (IL-2) (p< 0.01), interleukin-4 (IL-4) (p<0.001), interferon-gamma ($IFN-{\gamma}$) (p<0.01) and malondialdehyde (MDA) (p<0.001), and decreased the serum erythropoietin (EPO) activity (p<0.05). Administration of vitamin E significantly increased the S-IgA (p<0.001) in ileum and significantly improved the expression levels of occludin and $I{\kappa}B{\alpha}$, and decreased the expression levels of hypoxia-inducible factor 1 alpha and 2 alpha ($HIF-1{\alpha}$ and $HIF-2{\alpha}$), Toll-like receptors (TLR4), P-$I{\kappa}B{\alpha}$ and nuclear factor-${\kappa}B$ p65(NF-${\kappa}B$ P65) in ileum compared to the HH group. This study suggested that vitamin E protectis from intestinal injury caused by high altitude hypoxia environment. These effects may be related to the HIF and TLR4/NF-${\kappa}B$ signaling pathway.

Association Between the GSTP1 Codon 105 Polymorphism and Gastric Cancer Risk: an Updated Meta-analysis

Bao, Li-Dao,Niu, Jian-Xiang,Song, Hui,Wang, Yi,Ma, Rui-Lian,Ren, Xian-Hua,Wu, Xin-Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Objective: The current meta-analysis was performed to address a more accurate estimation of the association between glutathione S-transferase P1 (GSTP1) codon 105 polymorphism and risk of gastric cancer (GC), which has been widely reported with conflicting results. Methods: A comprehensive literature search was conducted to identify all the relevant studies. Fixed or random effect models were selected based on the heterogeneity test. Publication bias was estimated using Begg's funnel plots and Egger's regression test. Results: A total of 20 studies containing 2,821 GC cases and 6,240 controls were finally included in the analyses. Overall, no significant association between GSTP1 polymorphism and GC risk was observed in worldwide populations. However, subgroup analysis stratified by ethnicity showed that GSTP1 polymorphism was significantly associated with increased risk of GC in Asians (G vs. A, OR = 1.273, 95%CI=1.011-1.605; GG vs. AA, OR=2.103, 95%CI=1.197-3.387; GG vs. AA+AG, OR =2.103, 95%CI=1.186-3.414). In contrast, no significant association was found in Caucasians in any genetic models, except for with AG vs. AA (OR=0.791, 95%CI=0.669-0.936). Furthermore, the GSTP1 polymorphism was found to be significantly associated with GC in patients with H. pylori infection and in those with a cardiac GC. Subgroup analysis stratified by Lauren's classification and smoking status showed no significant association with any genetic model. No studies were found to significantly influence the pooled effects in each genetic mode, and no potential publication bias was detected. Conclusion: This meta-analysis suggested that the GSTP1 polymorphism might be associated with increased risk of GC in Asians, while GSTP1 heterozygote genotype seemed to be associated with reduced risk of GC. Since potential confounders could not be ruled out completely, further studies are needed to confirm these results.

Effect of Matrix Metalloproteinase on Autolysis of Sea Cucumber Stichopus japonicus

Li-Ming Sun,Ting-Ting Wang,Bei-Wei Zhu,Hai-Ling Niu,Rui Zhang,Hong-Man Hou,Gong-Liang Zhang,Yoshiyuki Murata 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.5

To investigate the relationship between matrix metalloproteinase (MMPs) and autolysis of sea cucumber Stichopus japonicus, the dermis homogenate was incubated at 25oC to induce autolysis. EDTA Na2 and 1,10-phenanthroline were used to verify the effect of MMPs on autolysis, which was measured by soluble protein and protein pattern. Soluble protein level increased during a 6-h autolysis process. SDS-PAGE demonstrated obvious protein degradation with the concomitant occurrence of degradation products. The above two indicators could be inhibited significantly by EDTA Na2 and 1,10-phenanthroline, indicating that MMPs might play a significant role in autolysis of sea cucumber.

Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease

Xiong Liu-Lin,Xue Lu-Lu,Du Ruo-Lan,Niu Rui-Ze,Chen Li,Chen Jie,Hu Qiao,Tan Ya-Xin,Shang Hui-Fang,Liu Jia,Yu Chang-Yin,Wang Ting-Hua 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

In recent years, biomarkers have been integrated into the diagnostic process and have become increasingly indispensable for obtaining knowledge of the neurodegenerative processes in Alzheimer’s disease (AD). Peripheral blood mononuclear cells (PBMCs) in human blood have been reported to participate in a variety of neurodegenerative activities. Here, a single-cell RNA sequencing analysis of PBMCs from 4 AD patients (2 in the early stage, 2 in the late stage) and 2 normal controls was performed to explore the differential cell subpopulations in PBMCs of AD patients. A significant decrease in B cells was detected in the blood of AD patients. Furthermore, we further examined PBMCs from 43 AD patients and 41 normal subjects by fluorescence activated cell sorting (FACS), and combined with correlation analysis, we found that the reduction in B cells was closely correlated with the patients’ Clinical Dementia Rating (CDR) scores. To confirm the role of B cells in AD progression, functional experiments were performed in early-stage AD mice in which fibrous plaques were beginning to appear; the results demonstrated that B cell depletion in the early stage of AD markedly accelerated and aggravated cognitive dysfunction and augmented the Aβ burden in AD mice. Importantly, the experiments revealed 18 genes that were specifically upregulated and 7 genes that were specifically downregulated in B cells as the disease progressed, and several of these genes exhibited close correlation with AD. These findings identified possible B cell-based AD severity, which are anticipated to be conducive to the clinical identification of AD progression.