http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Hu Qiao (검색결과 46 건)
- 무료
- 기관 내 무료
- 유료
-
miR-124 Inhibits Growth and Invasion of Gastric Cancer by Targeting ROCK1
Hu, Cong-Bing,Li, Qiao-Lin,Hu, Jian-Fei,Zhang, Qiang,Xie, Jian-Ping,Deng, Li Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16
MicroRNAs (miRNAs) act as critical regulators of genes involved in many biological processes. Aberrant alteration of miRNAs have been found in many cancers, including gastric cancer (GC), but the molecular mechanisms are not well understood. Herein, we investigated the role of miR-124 in GC. We found that its expression was significantly reduced in both GC tissue samples and cell lines. Forced expression of miR-124 suppressed GC cell proliferation, migration, and invasion. Furthermore, the Rho-associated protein kinase (ROCK1) was identified as a direct target of miR-124 in GC cells. Finally, silencing of ROCK1 showed similar effects as miR-124 overexpression, while supplementation of ROCK1 remarkably restored the cell growth and invasion inhibited by miR-124. Together, our data demonstrate that miR-124 acts as a tumor suppressor by targeting ROCK1, and posit miR-124 as a novel strategy for GC treatment.
-
Hu Jiaqi,Qiao Zhaopeng,Fan Lunhe,Tang Yongqiang,Cao Liangzhi,Zu Tiejun,He Qingming,Li Zhifeng,Wang Sheng 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.4
MgF2 as a moderator material has been extensively used in the beam shaping assembly (BSA) that plays an important role in the boron neutron capture therapy (BNCT). Regarded as important for applications, the thermal neutron scattering data of MgF2 were calculated, based on the phonon expansion model. The structural properties of MgF2 were researched by the VASP code based on the ab-initio methods. The PHONOPY code was employed to calculate the phonon density of states. Furthermore, the NJOY code was used to calculate the thermal neutron scattering data of MgF2. The calculated inelastic cross sections plus absorption cross sections are in agreement with the available experimental data. The neutron transport in the BSA has been simulated by using a hybrid Monte-Carlo-Deterministic code NECP-MCX. The results indicated that compared with the calculation of the free gas model, the thermal neutron flux and epithermal neutron flux at the BSA exit port calculated by using the thermal neutron scattering data of MgF2 were reduced by 27.7% and 8.2%, respectively.
-
Hu, Jiankun,Lu, Wenqing,Wang, Chunlin,Zhu, Ronghua,Qiao, Jiayun Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.11
This study investigated the effects of solid-state fermentation of a compound pig feed on its microbial and nutritional characteristics as well as on pig performance and nutrient digestibility. A mixed culture containing Lactobacillus fermentum, Saccharomyces cerevisae and Bacillus subtilis was used for solid-state fermentation and solid-state fermented feed samples were collected on days 0, 1, 2, 3, 5, 7, 10, 15, 20 and 30 for microbial counts and chemical analysis. Lactic acid bacteria increased rapidly during the first three days of fermentation and then slowly declined until day 10 and, thereafter, the counts were maintained at about 6.7 log cfu/g for the duration of the fermentation period. Enterobacteria also increased during the first two days, and then fell below the detectable level of the analysis (3.0 log cfu/g). The pH of the fermentation substrate declined from 6.1 at the start of fermentation to 5.7 by day 30. The water-soluble protein content increased from 8.2 to 9.2% while the concentration of acetic acid increased from 16.6 to 51.3 mmol/kg over the 30-day fermentation. At the end of the 30-day fermentation, the solid-state fermented feed was used in a pig feeding trial to determine its effects on performance and nutrient digestibility in growing-finishing pigs. Twenty crossbred barrows ($14.11{\pm}0.77kg\;BW$) were allotted into two dietary treatments, which comprised a regular dry diet containing antibiotics and a solid-state fermented feed based diet, free of antibiotics. There was no difference due to diet on pig performance or nutrient digestibility. In conclusion, solid-state fermentation resulted in high counts of lactic acid bacteria and low counts of enterobacteria in the substrate. Moreover, feeding a diet containing solid-state fermented feed, free of antibiotics, can result in similar performance and nutrient digestibility in growing-finishing pigs to a regular diet with antibiotics.
-
-
Cong Hu,Qiao Shi,Yang Xin,Wu Tian,Pu Ziheng 한국탄소학회 2022 Carbon Letters Vol.32 No.1
This work using first-principles theory proposed PdN3-doped CNT (PdN3-CNT) as a potential gas sensor for detection of NO, NO2 and O3 in the air insulated equipment, to evaluate its operation status. Results indicate that the PdN3-CNT behaves chemisorption upon three gas species, with adsorption energy (Ead) of − 2.15, − 1.91 and − 1.96 eV, and charge-transfer (QT) of − 0.141, − 0.325 and − 0.419 e, respectively. The band structure (BS) and density of state (DOS) analysis reveal that the gas adsorptions cause remarkable deformations in the electronic property of the PdN3-CNT, leading to the increase of the bandgap for the gas adsorbed systems and verifying the strong binding force of the bonded atoms from the orbital DOS. Combined with the results by frontier molecular orbital theory, we presume that PdN3-CNT is a promising sensing material to be explored as a resistance-type gas sensor for detection of NOx with higher electrical response upon NO. It is our hope that our theoretical assumption could be further studied and realized in the following experiential research, which would be meaningful to propose novel sensing candidate in the field of electrical engineering to guarantee the safe operation of the air insulation equipment.
-
Seismic performance analysis of steel-brace RC frame using topology optimization
Shengfang Qiao,Huqing Liang,Mengxiong Tang,Wanying Wang,Hesong Hu 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.71 No.4
Seismic performance analysis of steel-brace reinforced concrete (RC) frame using topology optimization in highly seismic region was discussed in this research. Topology optimization based on truss-like material model was used, which was to minimum volume in full-stress method. Optimized bracing systems of low-rise, mid-rise and high-rise RC frames were established, and optimized bracing systems of substructure were also gained under different constraint conditions. Thereafter, different structure models based on optimized bracing systems were proposed and applied. Last, structural strength, structural stiffness, structural ductility, collapse resistant capacity, collapse probability and demolition probability were studied. Moreover, the brace buckling was discussed. The results show that bracing system of RC frame could be derived using topology optimization, and bracing system based on truss-like model could help to resolve numerical instabilities. Bracing system of topology optimization was more effective to enhance structural stiffness and strength, especially in mid-rise and high-rise frames. Moreover, bracing system of topology optimization contributes to increase collapse resistant capacity, as well as reduces collapse probability and accumulated demolition probability. However, brace buckling might weaken beneficial effects.
-
-
Zhigang Hu,Wenlei Wang,Xianling Qiao 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.4
The purpose of this research is to study the cognitive preference of the old people in the color matching of assistive products. First of all, the elderly assistive products color matching was analyzed. Based on this point, the double color samples color matching software was designed, and there are 858 valid two Color harmony pictures were obtained. Secondly, there were 50 pairs of Kansei words were obtained through investigation and research. Using Multidimensional scaling method and Clustering analysis method, there were 5 pairs of representative Kansei words were extracted: "Emotional-rational", "Traditional-modern", "Natural-technological", "Massive-leggiere”, "Rigid-soft". According to above, were aimed to give score to 20 subjects(Contains the elderly group and young group)through the E-prime software, using the Likert scale to grade 858 valid two Color harmony pictures. The perceptual evaluation value of 5 pairs of representative Kansei words with 858 valid two Color harmony pictures were obtained. Finally, the different cognitive preference of double color matching for assistive products of the old people was obtained through the statistical analysis. The results can not only provide reasonable color recommendations, but also shorten the production cycle.
-
Research on Static Behavior of Stud Shear Connectors after Strong-corrosion Based on Push-out Test
Wenjing Qiao,Qihan Hu,Fan Yang,Haoyun Zhu 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.8
To study the shear bearing performance and failure mechanism of stud shear connectors after strong-corrosion, six groups of stud shear connectors were designed and then welded to the specimen. They are corroded by hydrochloric acid time for 0 h, 2 h, 12 h, 24 h, 48 h, and 72 h. Herein, the loading process, load-slip curve, shear bearing capacity, and failure mode were obtained by the push-out test. The bearing capacity formula was also proposed by the stress mechanism of 84 finite element models. The results of the study on stud shear connectors show that the shear capacity, deformation capacity and slip decrease gradually with the extension of corrosion time. Among them, the enlargement in the diameter exerts considerable influence on their shear capacity. Notwithstanding, the shear bearing capacity slightly increases with stud shear connectors lengthened. The concrete strength grade can strengthen the shear capacity. Finally, the shear bearing capacity formula, taking the reliability coefficient into account, is proposed by the exit test data of 104 stud shear connectors.
-
LIANG QIAO,YI ZENG,CHAOQUN QU,XIAOYING HU,LIJUN SONG,YONGMING SUI 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.1
The adsorption and difusion of oxygen atom on the O-terminated ZnO ð 000?1 Þ surface havebeen systematically investigated based on ¯rst-principles density functional theory. The resultsshow that the surface relaxation of the ZnO ð 000?1 Þ surface is signi¯cant. In the view of themaximization of the adsorption energy, the preferred site for the adsorption of oxygen atom is thetop-O site above the oxygen atom of the ¯rst Zn – O bilayer. There is chemical bond formedbetween the adsorbed oxygen atom and the oxygen atom on the surface, which will result in theredistribution of the charges. The charges transfer from the ZnO surface to the adsorbed oxygenatom, which will heighten the surface potential of ZnO surface and increase the surface workfunction. Moreover, the di®usion of the oxygen atom on the ZnO surface has also been investi-gated, and the potential barriers of the difusion have been identi¯ed to reveal the adsorptionstability
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
