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      • KCI등재

        Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam

        Minh Tam Le,Vu Quoc Huy Nguyen,Quang Vinh Truong,Dinh Duong Le,Viet Nguyen Sa Le,Ngoc Thanh Cao 대한내분비학회 2018 Endocrinology and metabolism Vol.33 No.4

        Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrinopathies among reproductive-age women. Its metabolic features often overlap with those associated with metabolic syndrome (MS) and insulin resistance syndrome (IRS). Theobjective of this study was to determine the prevalence and predictors of MS and IRS in infertile Vietnamese women with PCOS. Methods: A cross-sectional study was conducted at a tertiary fertility centre at Hue University Hospital from June 2016 to November 2017. A total of 441 infertile women diagnosed with PCOS based on the revised 2003 Rotterdam consensus criteria were enrolled. MS and IRS were defined based on the National Heart, Lung, and Blood Institute/American Heart Association Adult Treatment Panel III 2005 and American College of Endocrinology IRS 2003 criteria, respectively. Complete clinical and biochemicalmeasurements of 318 women were available for analysis. Independent predictors of MS and IRS were identified using multivariatelogistic regression. Results: The overall prevalence of MS and IRS in women with PCOS was 10.4% and 27.0%, respectively. We identified older age(>30 years) and obesity as independent predictors of MS and IRS. Elevated anti-Müllerian hormone levels increased the risk of IRS,but not that of MS. Conclusion: MS and IRS are prevalent disorders among infertile Vietnamese women with PCOS. PCOS is not solely a reproductiveproblem. Screening and early intervention for MS and/or IRS based on anthropometric, metabolic, and reproductive hormone riskfactors should be an integral part of fertility care.

      • KCI등재

        Pretreatment 18F-FDG PET/CT-Derived Parameters in Predicting Clinical Outcomes of Locally Advanced Upper Third Esophageal Squamous Cell Carcinoma After Definitive Chemoradiation Therapy

        Le Ngoc Ha,Nguyen Dinh Chau,Bui Quang Bieu,Mai Hong Son 대한핵의학회 2022 핵의학 분자영상 Vol.56 No.4

        Purpose The aim of this study was to investigate whether standard uptake values (SUVs) of pretreatment 18F-FDG PET/CT were the surrogate parameters for predicting the outcomes in locally advanced esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy. Materials and Methods Sixty patients with esophageal squamous cell carcinoma underwent pretreatment 18F-FDG PET/CT and received definitive chemoradiotherapy. 18F-FDG metabolic parameters including SUVmax, SUVmean, SULpeak, total lesion glycolysis (TLG), and metabolic tumor volume (MTV) of primary tumor were calculated. The receiver-operating characteristic (ROC) curve was used to determine the optimal cutoff value of FDG PET/CT-derived parameters that associated with treatment response. Estimating progression-free survival (PFS) and overall survival (OS) was analyzed by using Kaplan–Meier methods. Univariate and multivariate analysis for PFS and OS was performed using Cox regression. Results Complete response was achieved in 38.3%. The 4-year OS and PFS rates were 48.6% and 44.4%, respectively. SUVmean with a cutoff value of 6.1 could predict complete response with sensitivity of 69.6%, specificity of 78.4%, and accuracy of 75%. Cox multi-factor regression analyses revealed SUVmean > 6.1 as an independent prognostic factor for OS (HR = 6.74, p = 0.02) and PFS (HR = 6.53, p < 0.001). Conclusions Our study suggests that SUVmean of the primary tumor in pretreatment 18F-FDG PET/CT may be used as an independent predictor in esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy.

      • KCI등재

        Heat Transfer Performance Optimization of Rectangular Channel with Truncated-root Ribs

        Ky-Quang Pham,Van-Minh Le,Cong-Truong Dinh 한국유체기계학회 2022 International journal of fluid machinery and syste Vol.15 No.2

        Cooling designs inside the gas turbine blades of aircraft engines are aimed to solve a problem that has existed since the very beginning of the aerospace industry. Since the working environment of turbine blades is extremely harsh when the temperature can rise to 2000K, which is considered a huge challenge for any materials. Therefore, cooling designs such as rib turbulators have always been researched and optimized for better heat transfer enhancement in the cooling mechanism of turbine blades. In this study, a geometric optimization of the rib turbulators inside a rectangular channel was performed with the aim to maximize heat transfer performance. This study investigated the effect of four rib configurations on the heat transfer efficiency of the channel, which include square, truncated-root, convergent truncated-root, and divergent truncated-root rib. Thereby, a module of coupling Python and OpenFOAM was developed to automatically perform the optimization of truncated-root rib design at Reynolds number of 37,000 with design variables are the upstream and downstream height with Powell optimization method. The aim is to figure out the point where the maximum heat transfer performance of the channel is achieved. The study presented in a specific, productive, and accurate way the factors that directly and indirectly affect the heat transfer performance of the channel, thereby giving the optimal results that the channel has the highest heat transfer performance of the presented designs. The results show that the highest heat transfer performance of the optimized design is 12.45% higher than the standard square ribs case.

      • SCIESCOPUS

        A new hybrid sewage treatment system combining a rolled pipe system and membrane bioreactor to improve the biological nitrogen removal efficiency: A pilot study

        Bach, Quang-Vu,Le, Van Tam,Yoon, Yong Soo,Bui, Xuan Thanh,Chung, Woojin,Chang, Soon Woong,Ngo, Huu Hao,Guo, Wenshan,Nguyen, Dinh Duc Elsevier 2018 JOURNAL OF CLEANER PRODUCTION Vol.178 No.-

        <P><B>Abstract</B></P> <P>A new hybrid pilot plant configuration based on a modularized rolled pipe system (RPS) combined with a submerged flat sheet membrane bioreactor (MBR) was investigated to enhance the sewage treatment and membrane performance. The system was operated under actual conditions for more than four months, that is, at a constant flow rate of 30 m³/d and with two internal recycling ratios. The results indicate that the hybrid system produces an excellent effluent quality and considerably mitigated membrane fouling. The average concentrations of SS, COD, TN, NH<SUB>4</SUB> <SUP>+</SUP>-N, NO<SUB>3</SUB> <SUP>−</SUP>-N, and PO<SUB>4</SUB> <SUP>3-</SUP>-P remained below 2.81, 8.29, 8.77, 0.15, 8.17, and 1.49 mg/L, respectively. It was estimated that the periodic chemical cleaning of the membrane could be extended to approximately six months. The MBR and RPS can virtually complete nitrification and denitrification, respectively. The highest average denitrification rate of the RPS is 116.95 mg NO<SUB>3</SUB>-N/(g MLVSS d), with a hydraulic retention time of 1.05 h. Therefore, the RPS–MBR hybrid system has potential to improve the sewage treatability. The emerging RPS technique can obtain high rates of denitrification coupled with a compact design, ease of installation, and small footprint.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A new hybrid sewage treatment system was explored. </LI> <LI> Excellent denitrification is achieved with the novel rolled pipe system. </LI> <LI> High rates of simultaneous nitrification and denitrification are obtained. </LI> <LI> The hybrid system performs well in removing organic and nitrogen compounds. </LI> <LI> The membrane fouling rate of the hybrid system is significantly low. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Study on the Melting of the Defective Interstitial Alloys TaSi and WSi with BCC Structure

        Nguyen Quang Hoc,Tran Dinh Cuong,Bui Duc Tinh,Le Hong Viet 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.8

        The statistical moment method is used to study the melting of defective interstitial AB alloys, where A is the main element and B is an interstitial atom, with a body-centered-cubic (BCC) structure. The melting temperature of the AB alloy with defects is obtained from the temperature of absolute stability for the crystalline state and the equilibrium vacancy concentration. Numerical calculations are performed for the interstitial alloys TaSi and WSi. Our calculated results are in good agreement with other calculations.

      • KCI등재

        Absorption Coefficient of Weak Electromagnetic Waves Caused by Confined Electrons in Quantum Wires

        Nguyen Quang BAu,Tran Cong PHONG,Le DINH 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.II

        The quantum theory of the absorption of weak electromagnetic waves (EMWs) caused by confined electrons in quantum wires has been studied based on Kubo's linear response theory and Mori's projection operator method. Analytical expressions for the absorption coefficients of weak EMWs in quantum wires with electron-acoustic phonon and electron-optical phonon scattering mechanisms are obtained. The dependence of the absorption coefficient of a weak EMW on its frequency $\omega$ as system temperature $T$, and the parameters charactering the sample are analyzed. Numerical calculations have been done, and the results are discussed for a typical wire of GaAs/GaAsAl.

      • Optimization of Spin-Valve Structure NiFe/Cu/NiFe/IrMn for Planar Hall Effect Based Biochips

        Bui Dinh Tu,Le Viet Cuong,Tran Quang Hung,Do Thi Huong Giang,Tran Mau Danh,Nguyen Huu Duc,CheolGi Kim IEEE 2009 IEEE transactions on magnetics Vol.45 No.6

        <P>This paper deals with the planar Hall effect (PHE) of Ta(5)/NiFe(t<SUB>F</SUB>)/Cu(1.2)/NiFe(t<SUB>P</SUB>)/IrMn(15)/Ta(5) (nm) spin-valve structures. Experimental investigations are performed for 50 mumtimes50 mum junctions with various thicknesses of free layer (t<SUB>F</SUB> = 4, 8, 10, 12, 16, 26 nm) and pinned layer (t<SUB>P</SUB> = 1, 2, 6, 8, 9, 12 nm). The results show that the thicker free layers, the higher PHE signal is observed. In addition, the thicker pinned layers lower PHE signal. The highest PHE sensitivity S of 196 muV/(kA/m) is obtained in the spin-valve configuration with t<SUB>F</SUB> = 26 nm and t<SUB>P</SUB> = 1 nm. The results are discussed in terms of the spin twist as well as to the coherent rotation of the magnetization in the individual ferromagnetic layers. This optimization is rather promising for the spintronic biochip developments.</P>

      • SCIESCOPUS

        Antimicrobial efficacy of extracts and constituents fractionated from <i>Rheum tanguticum</i> Maxim. ex Balf. rhizomes against phytopathogenic fungi and bacteria

        Pham, Duong Quang,Ba, Duong Thi,Dao, Nga Thu,Choi, Gyung Ja,Vu, Thuy Thu,Kim, Jin-Cheol,Giang, Thi Phuong Ly,Vu, Hoang Dinh,Le Dang, Quang Elsevier 2017 INDUSTRIAL CROPS AND PRODUCTS Vol.108 No.-

        <P><B>Abstract</B></P> <P>The antimicrobial efficacies of extracts and constituents fractionated from <I>Rheum tanguticum</I> rhizomes were evaluated by using <I>in vitro</I> and <I>in vivo</I> bioassay against seven phytopathogenic fungi and ten pathogenic bacteria, respectively. Dichloromethane and ethyl acetate soluble extracts derived from <I>R. tanguticum</I> rhizomes effectively controlled plant diseases caused by five fungi <I>Magnaporthe oryzae</I>, <I>Blumeria graminis</I> f. sp<I>. hordei, Colletotrichum coccodes, Phytophthora infestans,</I> and <I>Puccinia recondita</I> in <I>in vivo</I> whole plant bioassay. In addition, these extracts showed strong inhibitory activity against the bacterial growth of <I>Acidovorax avenae</I> subsp. <I>cattlyae</I> (Aac), <I>Clavibacter michiganensis</I> subsp. <I>michiganensis</I>, <I>Xanthomonas arboricola</I> pv. <I>pruni</I> (Xap), and <I>Pseudomonas syringae</I> pv. <I>actinidiae</I> (Psa), with MIC values ranging from 125 to 250μg/mL. The active extracts of <I>R. tanguticum</I> rhizomes were fractionated by using various and repeated chromatographic techniques to yield seven constituents that included three anthraquinones and four stilbenes. Notably, at concentrations ranging from 75 to 300μg/mL, physcion (<B>DH03</B>) and chrysophanol (<B>DH04</B>) were significantly effective in suppressing the development of barley powdery mildew (BPM) caused by <I>B. graminis</I> f. sp. <I>hordei,</I> with control values from 80 to 96.7%. Moreover, stilbenes rhapontigenin (<B>DH02</B>) and desoxyrhapontigenin (<B>DH05</B>) had a broad spectrum and potent activity against phytopathogenic bacteria; <B>DH05</B> effectively inhibited the bacterial growth of Aac, <I>Burkholderia glumae</I> and Psa at MICs ranging from 38 to 150μg/mL. In this paper, we report their antibacterial activity for the first time. The botanical materials containing anthraquinones and stilbenes were active against both phytopathogenic fungi and bacteria. These results suggested that <I>R. tanguticum</I> rhizomes could be used as a new source of antimicrobial substances for developing a botanical fungicide and bactericide to control plant diseases.</P> <P><B>Highlights</B></P> <P> <UL> <LI> <I>R. tanguticum</I> extracts exhibited activity against phytopathogenic fungi and bacteria. </LI> <LI> Seven anthraquinones and stilbenes from <I>R. tanguticum</I> were isolated and identified. </LI> <LI> <I>In vivo</I> antifungal activity of botanicals was evaluated by the whole plant bioassay. </LI> <LI> The isolated stilbenes effectively inhibited the growth of phytopathogenic bacteria. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Aerodynamic Performance of an Annular Combustion Chamber Cooling with Swirler Design

        Cong-Truong Dinh,Xuan-Truong Le,Trong-Nghia Hoang,Quang-Anh Pham 한국유체기계학회 2021 International journal of fluid machinery and syste Vol.14 No.1

        Gas turbines play a crucial role in the aviation industry as they are primary sources of power for most aircraft. The combustion chamber is one of the three essential part of jet engines, together with compressor and turbine. Energy is generated when fuel is burned in the combustor. In the primary zone, the recirculation flow is of great importance to aerodynamic performance. Swirlers, fitted in the dome around the fuel injector, can alter the behavior of the recirculation flow and thus, impact combustion performance. The vortex behind a swirler can be easily controlled by changing the swirl angle. In addition, changing the vortex angle leads to a difference in mixing between fuel and air. This paper investigates the effects of swirler design, based on the swirl angle, on aerodynamic performance of an annular combustion chamber in cooling condition using three-dimensional Reynolds-averaged Navier-Stokes equations with the SST turbulence model.

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