Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam

Minh Tam Le,Vu Quoc Huy Nguyen,Quang Vinh Truong,Dinh Duong Le,Viet Nguyen Sa Le,Ngoc Thanh Cao 대한내분비학회 2018 Endocrinology and metabolism Vol.33 No.4

Background: Polycystic ovarian syndrome (PCOS) is one of the most common endocrinopathies among reproductive-age women. Its metabolic features often overlap with those associated with metabolic syndrome (MS) and insulin resistance syndrome (IRS). Theobjective of this study was to determine the prevalence and predictors of MS and IRS in infertile Vietnamese women with PCOS. Methods: A cross-sectional study was conducted at a tertiary fertility centre at Hue University Hospital from June 2016 to November 2017. A total of 441 infertile women diagnosed with PCOS based on the revised 2003 Rotterdam consensus criteria were enrolled. MS and IRS were defined based on the National Heart, Lung, and Blood Institute/American Heart Association Adult Treatment Panel III 2005 and American College of Endocrinology IRS 2003 criteria, respectively. Complete clinical and biochemicalmeasurements of 318 women were available for analysis. Independent predictors of MS and IRS were identified using multivariatelogistic regression. Results: The overall prevalence of MS and IRS in women with PCOS was 10.4% and 27.0%, respectively. We identified older age(>30 years) and obesity as independent predictors of MS and IRS. Elevated anti-Müllerian hormone levels increased the risk of IRS,but not that of MS. Conclusion: MS and IRS are prevalent disorders among infertile Vietnamese women with PCOS. PCOS is not solely a reproductiveproblem. Screening and early intervention for MS and/or IRS based on anthropometric, metabolic, and reproductive hormone riskfactors should be an integral part of fertility care.

Utility of narrow-band imaging with or without dual focus magnification in neoplastic prediction of small colorectal polyps: a Vietnamese experience

Tien Manh Huynh,Quang Dinh Le,Nhan Quang Le,Huy Minh Le,Duc Trong Quach 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.4

Background/Aims: Accurate neoplastic prediction can significantly decrease costs associated with pathology and unnecessary colorectal polypectomies. Narrow-band imaging (NBI) and dual-focus (DF) mode are promising emerging optical technologies for recognizing neoplastic features of colorectal polyps digitally. This study aimed to clarify the clinical usefulness of NBI with and without DF assistance in the neoplastic prediction of small colorectal polyps (<10 mm). Methods: This cross-sectional study included 530 small colorectal polyps from 343 consecutive patients who underwent colonoscopy at the University Medical Center from September 2020 to May 2021. Each polyp was endoscopically diagnosed in three successive steps using white-light endoscopy (WLE), NBI, and NBI-DF and retrieved for histopathological assessment. The diagnostic accuracy of each modality was evaluated with reference to histopathology. Results: There were 295 neoplastic polyps and 235 non-neoplastic polyps. The overall accuracies of WLE, WLE+NBI, and WLE+NBI+NBI-DF in the neoplastic prediction of colorectal polyps were 70.8%, 87.4%, and 90.8%, respectively (p<0.001). The accuracy of WLE+NBI+NBI-DF was significantly higher than that of WLE+NBI in the polyp size ≤5 mm subgroup (87.3% vs. 90.1%, p<0.001). Conclusions: NBI improved the real-time neoplastic prediction of small colorectal polyps. The DF mode was especially useful in polyps ≤5 mm in size.

Pretreatment 18F-FDG PET/CT-Derived Parameters in Predicting Clinical Outcomes of Locally Advanced Upper Third Esophageal Squamous Cell Carcinoma After Definitive Chemoradiation Therapy

Le Ngoc Ha,Nguyen Dinh Chau,Bui Quang Bieu,Mai Hong Son 대한핵의학회 2022 핵의학 분자영상 Vol.56 No.4

Purpose The aim of this study was to investigate whether standard uptake values (SUVs) of pretreatment 18F-FDG PET/CT were the surrogate parameters for predicting the outcomes in locally advanced esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy. Materials and Methods Sixty patients with esophageal squamous cell carcinoma underwent pretreatment 18F-FDG PET/CT and received definitive chemoradiotherapy. 18F-FDG metabolic parameters including SUVmax, SUVmean, SULpeak, total lesion glycolysis (TLG), and metabolic tumor volume (MTV) of primary tumor were calculated. The receiver-operating characteristic (ROC) curve was used to determine the optimal cutoff value of FDG PET/CT-derived parameters that associated with treatment response. Estimating progression-free survival (PFS) and overall survival (OS) was analyzed by using Kaplan–Meier methods. Univariate and multivariate analysis for PFS and OS was performed using Cox regression. Results Complete response was achieved in 38.3%. The 4-year OS and PFS rates were 48.6% and 44.4%, respectively. SUVmean with a cutoff value of 6.1 could predict complete response with sensitivity of 69.6%, specificity of 78.4%, and accuracy of 75%. Cox multi-factor regression analyses revealed SUVmean > 6.1 as an independent prognostic factor for OS (HR = 6.74, p = 0.02) and PFS (HR = 6.53, p < 0.001). Conclusions Our study suggests that SUVmean of the primary tumor in pretreatment 18F-FDG PET/CT may be used as an independent predictor in esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy.

Study on the Melting of the Defective Interstitial Alloys TaSi and WSi with BCC Structure

Nguyen Quang Hoc,Tran Dinh Cuong,Bui Duc Tinh,Le Hong Viet 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.8

The statistical moment method is used to study the melting of defective interstitial AB alloys, where A is the main element and B is an interstitial atom, with a body-centered-cubic (BCC) structure. The melting temperature of the AB alloy with defects is obtained from the temperature of absolute stability for the crystalline state and the equilibrium vacancy concentration. Numerical calculations are performed for the interstitial alloys TaSi and WSi. Our calculated results are in good agreement with other calculations.

Optimization of Spin-valve Structure NiFe/Cu/NiFe/IrMn for Planar Hall Effect Based Biochips

Bui Dinh Tu,Le Viet Cuong,Tran Quang Hung,Le Van Phong,Do Thi Huong Giang,Tran Mau Danh,Nguyen Huu Duc,Cheol Gi Kim 한국자기학회 2008 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Heat Transfer Performance Optimization of Rectangular Channel with Truncated-root Ribs

Ky-Quang Pham,Van-Minh Le,Cong-Truong Dinh 한국유체기계학회 2022 International journal of fluid machinery and syste Vol.15 No.2

Cooling designs inside the gas turbine blades of aircraft engines are aimed to solve a problem that has existed since the very beginning of the aerospace industry. Since the working environment of turbine blades is extremely harsh when the temperature can rise to 2000K, which is considered a huge challenge for any materials. Therefore, cooling designs such as rib turbulators have always been researched and optimized for better heat transfer enhancement in the cooling mechanism of turbine blades. In this study, a geometric optimization of the rib turbulators inside a rectangular channel was performed with the aim to maximize heat transfer performance. This study investigated the effect of four rib configurations on the heat transfer efficiency of the channel, which include square, truncated-root, convergent truncated-root, and divergent truncated-root rib. Thereby, a module of coupling Python and OpenFOAM was developed to automatically perform the optimization of truncated-root rib design at Reynolds number of 37,000 with design variables are the upstream and downstream height with Powell optimization method. The aim is to figure out the point where the maximum heat transfer performance of the channel is achieved. The study presented in a specific, productive, and accurate way the factors that directly and indirectly affect the heat transfer performance of the channel, thereby giving the optimal results that the channel has the highest heat transfer performance of the presented designs. The results show that the highest heat transfer performance of the optimized design is 12.45% higher than the standard square ribs case.

A new hybrid sewage treatment system combining a rolled pipe system and membrane bioreactor to improve the biological nitrogen removal efficiency: A pilot study

Bach, Quang-Vu,Le, Van Tam,Yoon, Yong Soo,Bui, Xuan Thanh,Chung, Woojin,Chang, Soon Woong,Ngo, Huu Hao,Guo, Wenshan,Nguyen, Dinh Duc Elsevier 2018 Journal of Cleaner Production Vol.178 No.-

<P><B>Abstract</B></P> <P>A new hybrid pilot plant configuration based on a modularized rolled pipe system (RPS) combined with a submerged flat sheet membrane bioreactor (MBR) was investigated to enhance the sewage treatment and membrane performance. The system was operated under actual conditions for more than four months, that is, at a constant flow rate of 30 m³/d and with two internal recycling ratios. The results indicate that the hybrid system produces an excellent effluent quality and considerably mitigated membrane fouling. The average concentrations of SS, COD, TN, NH<SUB>4</SUB> <SUP>+</SUP>-N, NO<SUB>3</SUB> <SUP>−</SUP>-N, and PO<SUB>4</SUB> <SUP>3-</SUP>-P remained below 2.81, 8.29, 8.77, 0.15, 8.17, and 1.49 mg/L, respectively. It was estimated that the periodic chemical cleaning of the membrane could be extended to approximately six months. The MBR and RPS can virtually complete nitrification and denitrification, respectively. The highest average denitrification rate of the RPS is 116.95 mg NO<SUB>3</SUB>-N/(g MLVSS d), with a hydraulic retention time of 1.05 h. Therefore, the RPS–MBR hybrid system has potential to improve the sewage treatability. The emerging RPS technique can obtain high rates of denitrification coupled with a compact design, ease of installation, and small footprint.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A new hybrid sewage treatment system was explored. </LI> <LI> Excellent denitrification is achieved with the novel rolled pipe system. </LI> <LI> High rates of simultaneous nitrification and denitrification are obtained. </LI> <LI> The hybrid system performs well in removing organic and nitrogen compounds. </LI> <LI> The membrane fouling rate of the hybrid system is significantly low. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Absorption Coefficient of Weak Electromagnetic Waves Caused by Confined Electrons in Quantum Wires

Nguyen Quang BAu,Tran Cong PHONG,Le DINH 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.II

The quantum theory of the absorption of weak electromagnetic waves (EMWs) caused by confined electrons in quantum wires has been studied based on Kubo's linear response theory and Mori's projection operator method. Analytical expressions for the absorption coefficients of weak EMWs in quantum wires with electron-acoustic phonon and electron-optical phonon scattering mechanisms are obtained. The dependence of the absorption coefficient of a weak EMW on its frequency $\omega$ as system temperature $T$, and the parameters charactering the sample are analyzed. Numerical calculations have been done, and the results are discussed for a typical wire of GaAs/GaAsAl.

Optimization of Spin-Valve Structure NiFe/Cu/NiFe/IrMn for Planar Hall Effect Based Biochips

Bui Dinh Tu,Le Viet Cuong,Tran Quang Hung,Do Thi Huong Giang,Tran Mau Danh,Nguyen Huu Duc,CheolGi Kim IEEE 2009 IEEE transactions on magnetics Vol.45 No.6

<P>This paper deals with the planar Hall effect (PHE) of Ta(5)/NiFe(t<SUB>F</SUB>)/Cu(1.2)/NiFe(t<SUB>P</SUB>)/IrMn(15)/Ta(5) (nm) spin-valve structures. Experimental investigations are performed for 50 mumtimes50 mum junctions with various thicknesses of free layer (t<SUB>F</SUB> = 4, 8, 10, 12, 16, 26 nm) and pinned layer (t<SUB>P</SUB> = 1, 2, 6, 8, 9, 12 nm). The results show that the thicker free layers, the higher PHE signal is observed. In addition, the thicker pinned layers lower PHE signal. The highest PHE sensitivity S of 196 muV/(kA/m) is obtained in the spin-valve configuration with t<SUB>F</SUB> = 26 nm and t<SUB>P</SUB> = 1 nm. The results are discussed in terms of the spin twist as well as to the coherent rotation of the magnetization in the individual ferromagnetic layers. This optimization is rather promising for the spintronic biochip developments.</P>

Green synthesis of finely-dispersed highly bactericidal silver nanoparticles via modified Tollens technique

Anh-Tuan Le,P.T. Huy,Phuong Dinh Tam,Tran Quang Huy,A.A. Kudrinskiy,Yu A. Krutyakov 한국물리학회 2010 Current Applied Physics Vol.10 No.3

In this article, we represent a versatile and effective technique which using non-toxic chemicals to prepare stable aqueous dispersions of silver nanoparticles (NPs) via modified Tollens process. It was shown that as-prepared silver colloids consisted of finely-dispersed NPs with average diameter about 10 nm and a relatively narrow size distribution. Moreover, they could be stored very stable after several months without observation of aggregates or sedimentation. In comparison with previous works where Tollens process was being used, we for the first time applied UV-irradiation simultaneously with glucose reduction of silver salt through NPs preparation. The colloidal solutions of silver NPs were found to exhibit a high antibacterial activity against gram-negative Escherichia coli. The concentration of silver leading to a complete inhibition of bacteria growth was revealed as low as at 1.0 ㎍ml-1 and found much lower compared to earlier reports. These advantages of aqueous dispersions of silver NPs make them ideal for green industrial, medicinal, microbiological and other applications.