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      • SCOPUSKCI등재

        Distribution of Factors Affecting Foreign Direct Investment in ASEAN Countries

        Anh Thi Lan NGUYEN(Anh Thi Lan NGUYEN ),Chau Thi Minh PHAM(Chau Thi Minh PHAM ),Hanh Hong NGUYEN(Hanh Hong NGUYEN ),Dat Ngoc NGUYEN(Dat Ngoc NGUYEN ),Duy Van NGUYEN(Duy Van NGUYEN ) 한국유통과학회 2023 유통과학연구 Vol.21 No.2

        Purpose: Research on attracting foreign direct investment plays an important role in ASEAN countries. ASEAN has needed FDI capital for development and integration with many developing countries. Research design, data and methodology: This study is conducted to assess the impact of factors: inflation (INF), economic growth (GDP), population (POP), and trade (TRADE) on attracting foreign direct investment (FDI) of ASEAN countries. The study will find out how factors distribution contributes to FDI attraction. The study collects data from 10 ASEAN countries from 2010 to 2020. With data collected for ten countries from 2010 to 2020, data analysis with panel data will be used in this study. The Regression with Driscoll-Kraay standard errors correction model will be used in the study. Results: Panel data analysis shows that economic growth and population positively impact FDI attraction in ASEAN countries. However, two factors: INF and TRADE, do not affect FDI. Conclusions: Countries need to focus on economic development, create many good conditions for people and domestic enterprises and create opportunities for foreign investors to pay more attention. improving the quality of domestic human resources will help to better improve the working quality factor when the demand for high-quality human resources increases.

      • KCI등재

        Anticancer Activity of the Potential Pyropia yezoensis Galactan Fractionated in Human Prostate Cancer Cells

        Thi Ngoc Anh Pham,Bao Le,양승환 한국생물공학회 2021 Biotechnology and Bioprocess Engineering Vol.26 No.1

        Galactan is a major sulfate polysaccharide in the red seaweed, Pyropia yezoensis. In the present study, the prebiotic potential and anticancer activities of three sulfate galactans with different molecular weights (GPYcrude, GPY300, and GPY10) were evaluated in vitro. Monosaccharide composition and structural analyses of these sulfate galactans showed that all polysaccharide fractions contained the same monosaccharides but had different molecular weights. All the polysaccharides tested displayed potential prebiotic activity, with GPY10 noticeably having the best potential compared to others, especially for Bifidobacterium spp., which highlights possible correlations between structural galactan features and prebiotic activity. Furthermore, all three sulfate galactans were cytotoxic to DU145 and PC-3 prostate cancer cells, with GPY10 exhibiting the greatest inhibition in DU145 cells. Moreover, GPY10 induced modulates the production of intracellular reactive oxygen species (ROS), with subsequent increased apoptosis of DU145 prostate cancer cell and modulating the PI3K/AKT/ mTOR signaling pathway. GPY10 increased expression of Bax, executor caspase-3, and initiator caspases 8 and 9. Therefore, sulfate galactans from P. yezoensis could be applied as a novel prebiotic and anticancer compounds in prostate cancer cells.

      • KCI등재

        Shift of Vietnamese Consumer E-purchasing Behavior During and After Covid-19 Pandemic

        ANH Pham Thi Cam,PHUONG Nguyen Mai,GIANG Nguyen Huong,LINH Pham Ngoc Mai,GIANG Nguyen Huong 한국유통과학회 2024 유통과학연구 Vol.22 No.1

        Purposes: The study aimed at examining the impact of the COVID-19 pandemic on the shift of online consumer purchasing behavior and whether the new behaviors would be maintained after the epidemic season. The study also aims to investigate how online customers change based on perceived risks. Research design and Methodology: The study investigated purchasing behavior of the same 377 online Vietnamese consumers during two periods: (1) during the period of social distancing and (2) one and half year after that, allowing data to be collected in real time, so that consumers do not have to recall their behavior. Results: Purchasing behavior appeared to be more influenced by gender, age and household size. Aged consumers are more concerned about risks than those in the younger group, who only worry about the risks during the pandemic. Consumers in households with two or more people are more concerned about the risks than those living alone. Female appeared to be more influential in both during and after pandemic than male. Conclusions: The findings contribute to clarify shift of online consumer purchasing behavior, which helps business to develop effective marketing strategies and enhance their presence in the e-commerce sector.

      • KCI등재

        Anti-aging skin and antioxidant assays of protein hydrolysates obtained from salted shrimp fermented with Salinivibrio cibaria BAO-01

        Pham Thi Ngoc Anh,Bao Le,양승환 한국응용생명화학회 2020 Journal of Applied Biological Chemistry (J. Appl. Vol.63 No.3

        This study focused on the preparation and characterization of anti-wrinkle peptides from the salted and fermented shrimp (Acetes japonicus) inoculated with Salinivibrio cibaria BAO-01 (SFSC). The results showed the proximate composition of SFSC to be 9.23% water, 75.32% protein, 0.23% fat, and 13.3 mg/g ash. Interestingly, the S. cibaria fermentation significantly increased the amount of methionine, leucine, and arginine. The in vitro antioxidant activity was assayed by the diphenylpicrylhydrazyl method and its IC50 value was found to be 43.02±2.84 μg/mL. It was observed to inhibit the activity of elastase, tyrosinase, collagenase, and hyaluronidase. The IC50 values of SFSC were 182.75±12.38 μg/mL for anti-elastase activity, 186.78±7.95 μg/mL for anti-tyrosinase activity, 444.4±34.81 μg/mL for anti-collagenase activity, and 1447.95±28.92 μg/mL for anti-hyaluronidase activity. These results suggest that salted and fermented shrimp has strong potential for the development of nutricosmetic products.

      • KCI등재

        Anti-inflammatory Effects of Scrophularia buergeriana Extract Mixture Fermented with Lactic Acid Bacteria

        Thi Ngoc Anh Pham,Hae Lim Kim,이동령,최봉근,양승환 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.3

        Scrophularia buergeriana (SB) was once thought to be an herbal remedy with a wide range of uses. Lactobacillus transformation improves the medicinal benefits of biological substances. However, the effect of fermented SBE in macrophages on inflammatory expression is unknown. Furthermore, the synergistic effects of SBE and lactic acid bacteria (LAB) have not been previously investigated. Therefore, in the present study, we investigated the mixture of SB fermented with different lactic acid bacteria (LAB) strains, and analyzed their characteristics before and after fermentation. The results showed that LAB activities increased the levels of phenolic compounds, flavonoids, and iridoids, and SB extract (SBE) stimulated the growth of Lactobacillus strains. Moreover, we also determined the anti-inflammatory effects of the SBE fermented sample in lipopolysaccharide-treated RAW264.7 cells. It was observed that the treatment of SBE fermented sample inhibited nitric oxide (NO) production than SBE and also decreased the RNA expression of iNOS, IL-1β, IL-6, TNF-α, and COX-2. The results of this study indicate the potential anti-inflammation activity of lactic acid bacteria-fermented SBE as nutraceutical ingredients.

      • KCI등재

        Anti-Inflammatory Effects of the Chemical Compounds Obtained from Celastrus hindsii in RAW264.7 Cells

        Pham Thi Ngoc Anh,Hae Lim Kim,Oh Suwon,양승환 한국미생물·생명공학회 2022 한국미생물·생명공학회지 Vol.50 No.1

        Celastrus hindsii (family Celastraceae) is located abundantly in the United States, China, and Vietnam, where it is utilized as a traditional herbal and traditional drug for the care of cancer. However, the antioxidant and anti-inflammatory effects of Celastrus hindsii extract are unknown. In our research, the antioxidant activity of Celastrus hindsii leaf extract was investigated, and then anti-inflammatory efficacy of C. hindsii extract in lipopolysaccharide (LPS)-induced RAW264.7 cells. First, our results revealed that C. hindsii extract showed powerful antioxidant capability. Moreover, the application of C. hindsii extract significantly reduced nitric oxide (NO) production without cytotoxic effects. Furthermore, C. hindsii extract reduced the generation of pro-inflammatory cytokines, like as interleukin (IL)-6, IL-1β, and TNF-α. Our results are the first to confirm the anti-inflammatory capability of C. hindsii extract in RAW264.7 cells.

      • Tobacco Access and Availability for Vietnamese School Children (aged 13-15): Results from the Global Youth Tobacco Use Survey (GYTS) 2014 in Viet Nam

        Le, Thi Kim Anh,Bui, Thi Tu Quyen,Hoang, Van Minh,Kim, Bao Giang,Phan, Thi Hai,Doan, Thu Huyen,Luong, Ngoc Khue,Nguyen, Tuan Lam,Pham, Thi Quynh Nga Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1

        Efforts to reduce tobacco use among school children need to be based on understanding of access to cigarettes by these subjects because previous studies indicated that enforcement of laws for controlling tobacco sales seems to not affect teen/school children because they can obtain cigarettes from different sources. This paper aims to describe access to and availability of cigarettes among school students (aged 13-15 years old) according to the data from GYTS Vietnam 2014. In GYTS, a national school-based survey of students of grades 8-10, our findings showed that about 15% school children are current smokers who smoke at home, and that they could easily buy cigarettes from stores (63.2%), or someone else (27.8%), or street vendors (9%). Notably, over 85% of school children answered that they were not refused because of their age. This high percentage was nearly the same in the North (85.7%), the Centre (92.5%), and the South (89.7%) of Viet Nam. These findings show that it is quite easy for school children to obtain cigarettes and this is a crucial challenge for policy makers aiming to reduce tobacco use among youth in general and school-age students in particular.

      • KCI등재

        ĐÁNH GIÁ KHẢ NĂNG LÀM LÀNH VẾT BỎNG TRÊN CHUỘT CỦA HYDROGEL TỪ AgNP-CHITOSAN-CURCUMIN

        Hoang Ngoc Anh Nhan,Nguyen Ba Trung,Giang Thi Kim Lien,Truong Thi My Phuong,Ho Kha Vinh Nhan,Pham Xuan Anh 한국베트남학회 2023 베트남연구 Vol.21 No.1

        Skin burn is one of the major causes of morbidity and mortality in burn patients due to its susceptibility to infection. The disruption of the epidermal barrier, combined with the denaturation of proteins and lipids, provides a fertile environment that is rich in bacterial nutrients for microbial growth, making it significantly prone to infection. This study aimed to formulate a thermoresponsive hydrogel containing silver nanoparticles (300 ppm), oligo chitosan 2%, and curcumin (0.1%) in the polymer pluronic F127 matrix with a final concentration of 13% to effectively promote the healing of skin wounds. The prepared thermoresponsive hydrogel was investigated for its physical and chemical stability, gelation temperature, and chemical composition. In addition to in vitro antibacterial activity against Staphylococcus aureus found in burn infections, in vivo burn healing and antibacterial activities were also investigated and compared with those of a commercial product using burn-induced infected wounds in mice. The formulation showed antibacterial activity with effective values for wound healing properties, as shown in vivo and by histopathological studies. This study also demonstrates that the thermoresponsive hydrogel was successful as an antibacterial and burned wound-healing transdermal drug delivery system.

      • KCI등재

        ALMA OBSERVATIONS OF W HYDRAE: IMPACT OF MISSING BASELINES

        Do Thi Hoai,Tuan-Anh Pham,Pham Tuyet Nhung,Pierre Darriulat,Pham Ngoc Diep,Nguyen Bich Ngoc,Tran Thi Thai 한국천문학회 2021 Journal of The Korean Astronomical Society Vol.54 No.6

        The lack of short baselines, referred to as the short-spacing problem (SSP), is a well-known limitation of the performance of radio interferometers, causing a reduction of the flux detected from source structure on large angular scales. The very large number of antennas operated in the Atacama Large Millimeter/sub-millimeter Array (ALMA) generates situations for which the impact of the SSP takes a complex form, not simply measurable by a single number, such as the maximal recoverable scale. In particular, extended antenna configurations, complemented by a small group of closeby antennas at the centre of the array, may result in a double-humped baseline distribution with a significant gap between the two groups. In such cases one should adopt as the effective maximal recoverable scale the one associated with the extended array and use only the central array to recover missing ux, as one would do with single dish or ACA (Atacama Compact Array) observations. The impact of the missing baselines can be very important and may easily be underestimated, or even overlooked. The present study uses ALMA archival data of the ^{29}SiO(8-7) line emission of the AGB star W Hydrae for a demonstration. A critical discussion of the reliability of the observations away from the star is presented together with comments of a broader scope. Properties of the circumstellar envelope of W Hya within ~15 au from the star, many of which are not mentioned in the published literature, are briefly described and compared with R Doradus, an AGB star having properties very similar to W Hya.

      • KCI등재

        An overview bioactive compounds on the skin of frogs (Anura)

        Tran Thi Huyen,Phan Thi Hoang Anh,Nguyen Thi Anh Hong,Nguyen Ngoc Duyen,Le Pham Tan Quoc,Tran Dinh Thang 한국수산과학회 2023 Fisheries and Aquatic Sciences Vol.26 No.4

        The robust development of frog farming offered high economic benefits but created a large waste residue of frog bones and skin that received little attention. Over the years, inedible by-products have often been processed into biomolecules of potential value and environmental benefits, such as collagen, gelatin, and bioactive peptides. An overview of bioactive compounds on frog skins from various countries indicated that brevinin was the most abundant biological peptide found in frog skin. Other remaining compounds also possessed their highlighted activities, including antibacterial, stimulating insulin release and gastric hormone release, anti-cancer, and neuroregulatory. Notably, various components have been analyzed in the structure and sequence to give meaningful insight into clustering components related to their biological activity. This review may create a source of raw materials for the developmental research of by-products from frog skin and concomitantly reduce environmental pollution.

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