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      • 다공성 고분자수지 충전층에서 CO₂의 확산 및 분산

        박인수,김학준 慶南大學校 附設 工業技術硏究所 1984 硏究論文集 Vol.2 No.-

        이원세공고분자수지인 Amberlite XAD-2, XAD-4, XAD-7, 그리고 Amberlyst 15 충전층에서 CO₂의 확산계수 및 분산계수를 추산하기 위하여 선형흡착이론을 만족하는 저농도에서 펄스-응답의 모멘트를 해석하였다. 흡착열은 XAD-2<XAD-4<XAD-7<Amberlyst 15의 순서였다. 마이크로세공확산의 활성화에너지의 크기도 흡착열의 크기와 같은 순서였다. XAD-2의 경우, 마크로세공의 겉보기굴곡도는 1보다 작은 값인 0.8 이었으며, 이는 마크로세공에서 기상확산과 경쟁적으로 표면확산이 일어남을 시사한다. In order to estimate diffusion coefficient and axial dispersion coefficient of CO₂ in fixed bed of Amberlite XAD-2, XAD-4, XAD-7,and Amberlyst 15, we analysed moments of the pulse-response in the range of low concentration obeying the linear adsorption theory. The series of the heat of adsorption and the activation energy of micropore diffusion obtained from the first absolute moment and the second central moment were found to be XAD-2<XAD-4<XAD-7<Amberlyst 15. In the case of XAD-2, apparent tortuosity factor in macropore was found to be 0.8, less than unity. This indicates that surface diffusion takes place with gas phase diffusion compatatively in macropore.

      • Pt와 PbO₂전극에서 Iodide의 Cyclic Voltammetry

        박인수,김학준 慶南大學校 附設 工業技術硏究所 1983 硏究論文集 Vol.1 No.-

        지지전해질중에서 요오드화염의 전해산화반응을 검토하기 위하여 백금과 이산화납 전극에 대한 삼감전위주사법으로 싸이클릭 볼타모그램을 작성하여 비교하였다. 요오드 이온에 대한 백금의 전극반응은 산성하에서는 I₁??→I₂와 I₂→IO₃??의 두단계 반응으로 진행되는데, 전자는 가역적이고 후자는 비가역적이며 확산율속과정이다. 알칼리성에서는 I??→I₂와 I??→IO₃??의 두단계 반응으로서 비가역 과정이다. 요오드 이온에 대한 이산화납의 전극반응은 산성하에서는 PbO₂+2I??+2H?? →PbO+I₂+H₂O의 화학적인 반응과 그리고 I₂→IO₃??와 산소발생의 경쟁적인 반응이 일어나며, 알칼리성에서는 I??→IO₃??의 반응이 산소발생과 경쟁적으로 일어난다. Cyclic voltammetry and macro electrolysis studies are reported on platinum and lead dioxide electrodes for iodide in each supporting electrolyte. The oxidation of iodide due to platinum electrode reaction proceeds with two steps; the first corresponds to I??→I₂in both acid and alkali, and the second to I??→IO₃?? in acid and I??→IO₃?? in alkali. The former is reversible in acid and irreversible in alkali, while the latter is irreversible and diffusion rate controlling process. The oxidation of iodide due to lead dioxide reaction proceeds with two steps in acid; the first correcponds to PbO₂+2I??+2H??/ →PbO+I₂+H₂O chemically and the second to I₂→IO₃?? competed against oxygen gas evloution. In alkali, electrode reaction of I?? →IO₃? compete with O₂evolution.

      • 천연자원의 간기능 보호 효과에 관한 연구 : Benzo(a)pyrene에 의한 간기능 장해에 미치는 황금(Scutellaria baicalensis)의 영향 The Effect of Scutellariae Radix on the Benzo(a)pyrene-induced Hepatotoxicity in Rats

        윤수홍,조수열,배선희,박상학 효성여자대학교 부설 한국환경위생연구소 1991 환경위생연구 Vol.1 No.1

        환경 중의 어디에나 분포하여 인체에 발암작용을 일으키는 대표적인 약물 benzo(a)pyrene를직접 경구투여하고.동시에 간보호물질로서 황금을 전처리 투여하여 그 독성 및 손상 회복호과를 혈청 및 간에서의 효소활성을 측정하여 다음과 같은 결론을 얻었다. 1. 황금 수용액의 전처리로 혈칭에서 LDH, AST 및 ALT활성은 beozo(a)pyrene단독투여군에비하여 감소하였으며 ALT는 2,4주째에 유의성 있는 감소를 보였으나 ALP활성은 전 실험군과 시간경과사이에 별다른 유의성이 없었다. 2. 간장의 LDH, ALP, ALT, AST의 효소활성은 황금수용액의 투여로 benzo(a)pyrene 단독투여군에 비해 유의성 있는 회복을 보였으며 LDH의 경우는 2, 3, 4주에 매우 큰 효과를얻었으며 ALP의 경우 4주째에서 유의성 있게 회복되는 경향을 보였다. This study was conducted in an attempt to investigate the effectsof Scutellariae Radix on the activities of serum and liver enzyme and to evaluatethe utility of Scultellariae Radix as a hepatotropic agents in liver disease The results were as follows ; 1. Significantly increased enzyme activity was noted in benzo(a)pyrene-intoxica-ted rats. 2. Scutellariae Radix administration prevented the leackage of LDH, ALP, ALTand AST in serum. 3. Scutellariae Radix administration did not affect on the serum ALP activity. 4. The B(a) P induced liver toxicity was significantly decreased in ScutellariaeRadfx administration.

      • Tulipa gesneriana의 組織培養에 關한 硏究 : Ⅰ. Callus 誘起에 미치는 2,4-D와 Kinetin의 效果 Ⅰ. Effects of 2,4-D and Kinetin on the callus induction

        李炳基,朴鶴封,宋鎭水 全北大學校 1984 論文集 Vol.26 No.-

        Effects of 2,4-dichlorophenoxyacetic acid(2,4-D) and kinetin on the induction and growth of calluses of Tulipa gesneriana cv. Golden Apeldoorn were investigated in vitro. Style tissues were cultured on Murashige and Skoog's media containing various levels of 2, 4-D and kinein. The calluses were induced vigorously from the medium supplemented with 1-2mg/ι 2,4-d and 0.5-lmg/ι kinetin, Espcially, the friable calluses like protuberance were formed from the medium containing 2mg/ι 2,4-D and 1mg/ι kinetin. The poor calluses were initiated from the medium supplemented with 1mg/ι 2,4-D or 1mg/ι kinetin only.

      • KCI등재
      • KCI우수등재

        컴퓨터 바이러스에 감염된 소프트웨어의 신뢰도 측정

        박학수(Hark Soo Park),이강수(Gang Soo Lee),김규년(Kyunyun Kim),우치수(Chi Su Wu) 한국정보과학회 1990 정보과학회논문지 Vol.17 No.6

        본 논문에서는 소프트웨어 신뢰도 관점에서 바이러스에 관한 연구결과를 논한다. 우선, 소프트웨어 신뢰도와 바이러스에 관련된 일반사항을 논하고 특히, 바이러스의 특성과 국내의 대학과 전산학원내의 바이러스 감염율을 조사하였다. 또한, Gleissner의 감염 확산 모형에 대한 간략형인 새로운 감염 확산 모형을 제시하였다. 감염 확산 모형은 사용자 프로그램 집합내로 바이러스가 확산되는 현상을 나타낸다. 끝으로, 감염된 프로그램의 신뢰도 악화현상을 나타내는 모형을 제시하였다. In this paper, we describe some results of works on computer viruses in view of software reliability concept. We begin with bibliographic summary and some problems in software reliability and computer viruses, especially the characteristics of virus and the ratio of infection of virus in a university and some educational institutes of computer in Korea. We then introduce a model which representes the diffusion of virus into the set of user programs. The virus diffusion model can be used as a simplification and presumptive model of Gleissner's. Finally, we introduce a model which representes the degenerative reliability characteristics of an infected program.

      • KCI우수등재
      • KCI등재

        A Comprehensive and Comparative Review of Global Gastric Cancer Treatment Guidelines

        Eom Sang Soo,Choi Wonyoung,Eom Bang Wool,Park Sin Hye,Kim Soo Jin,Kim Young Il,Man Yoon Hong,Lee Jong Yeul,Kim Chan Gyoo,Kim Hark Kyun,Kook Myeong-Cherl,Choi Il Ju,Kim Young-Woo,Park Young Iee,Ryu Keu 대한위암학회 2022 Journal of gastric cancer Vol.22 No.1

        Countries differ in their treatment expertise and research results regarding gastric cancer; hence, treatment guidelines are diverse based on evidence and medical situations. A comprehensive and comparative review of each country’s guidelines is imperative to understand the similarities and differences among countries. We reviewed and compared five gastric cancer treatment guidelines in terms of endoscopic, surgical, perioperative, and palliative systemic treatment based on evidence levels and recommendation grades, as well as the postoperative follow-up strategies for each guideline. The Korean, Chinese, and European guidelines provided evidence and grading of the recommendations. The United States guidelines suggested categories for evidence and consensus. The Japanese guidelines suggested evidence and recommendations only for systemic treatment. The Korean and Japanese guidelines described endoscopic treatment, surgery, and lymphadenectomy in detail. The Chinese, United States, and European guidelines more intensively considered perioperative chemotherapy. In particular, the indications for chemotherapy and the regimens recommended by each guideline differed slightly. Considering their medical situations, each guideline had some diversity in terms of adopting evidence, which resulted in heterogeneous recommendations. This review will help medical personnel to comprehensively understand the diversity in gastric cancer treatment guidelines for each country in terms of evidence and recommendations.

      • SCOPUSKCI등재

        메산지움 세포에서 Lipopolysaccharide에 의해 유도되는 Chemokine 유전자 발현

        박종욱,임학,윤수정 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.6

        This study was designed to investigate the molecular mechanism of chemokine induction by lipopoly-saccharide(LPS) of E. coli. Chemokine gene expression was evaluated by the reverse transcriptase-polymerase chain reaction(RT-PCR) assay using RNAs isolated either from kidneys of LPS-injected inice or from the mesangial cells stimulated with LPS, IFN-γor TNF-α. LPS was shown to induce interferon gamma(IFN-γ) inducible protein 10 (IP-10) and monokine induced by interferon gamma (MIG) in kidney. IP-10 gene expression was induced by LPS and IFN-γ, but MIG gene expression was induced by IFN-γin mesangial cell. Chemokines induced by LPS increased splenocyte migration. Sodium salicylate, wortmanin and piperazine blocked LPS mediated chemokine induction suggesting the activation of nuclear factor-γB pathway. It is concluded from this study that mesangial cells are the target of LPS in the renal failure resulting from the systemic infections. LPS induces chemokines directly and/or indirectly in the mesangial cells, and these chemokines may associated with renal inflammation.

      • SCIESCOPUSKCI등재

        Pityriasis Lichenoides-like Mycosis Fungoides: Clinical and Histologic Features and Response to Phototherapy

        ( Min Soo Jang ),( Dong Young Kang ),( Jong Bin Park ),( Joon Hee Kim ),( Kwi Ae Park ),( Hark Rim ),( Kee Suck Suh ) 대한피부과학회 2016 Annals of Dermatology Vol.28 No.5

        Background: Pityriasis lichenoides (PL)-like skin lesions rarely appear as a specific manifestation of mycosis fungoides (MF). Objective: We investigated the clinicopathological features, immunophenotypes, and treatments of PL-like MF. Methods: This study included 15 patients with PL-like lesions selected from a population of 316 patients diagnosed with MF at one institution. Results: The patients were between 4 and 59 years of age. Four patients were older than 20 years of age. All of the patients had early-stage MF. In all patients, the atypical lymphocytic infiltrate had a perivascular distribution with epidermotropism. The CD4/CD8 ratio was <1 in 12 patients. Thirteen patients were treated with either narrowband ultraviolet B (NBUVB) or psoralen+ultraviolet A (PUVA), and all of them had complete responses. Conclusion: PL-like MF appears to have a favorable prognosis and occurrence of this variant in adults is uncommon. MF should be suspected in the case of a PL-like skin eruption. Therefore, biopsy is required to confirm the diagnosis of PL-like MF, and NBUVB is a clinically effective treatment. (Ann Dermatol 28(5) 540∼547, 2016)

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