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Sano, Tetsuro,Lin, Huai,Chen, Xiashan,Langford, Lauren A.,Bondy, Dimpy Koul Melissa L.,Hess, Kenneth R.,Myers, Jeffery N.,Hong, Yong-Kil,Yung, W.K. Alfred,Steck, Peter A. 가톨릭대학교 2000 Bulletin of The Catholic Research Institutes of Me Vol.28 No.-
MMAC/PTEN, a tumor suppressor gene located on chromosome 10q, has recently been shown to act as a phosphatidylinositol 3,4,5-triphosphate phosphatase and to modulate cell growth and apoptosis. Somatic mutations of MMAC/PTEN have been reported in a number of human cancers, especially in glioblastoma multiforme (GBM), although the number of identified mutations (10-35%) is significantly lower than the frequency of LOH affecting the MMAC/PTEN locus in the specimens (75-95%). To further investigate the possible alterations that may affect MMAC/PTEN, we examined the expression of the gene by reverse transcription-PCR in a series of gliomas. A significant difference (P<0.001) was observed between the expression of MMAC/PTEN in GBMs versus lower grades of gliomas, thus mimicking the difference in allelic deletion associated with the locus in these tumors. Furthermore, Kaplan-Meier survival plots, adjusted for age and tumor grade, showed a significantly better prognosis for patients whose tumors expressed high level of MMAC/PTEN. Additionally, immunostaining of GBMs revealed little or no MMAC/PTEN expression in about two-thirds of the tumors, whereas the other approximately one-third of tumors had significantly higher levels of expression. However, in about two-thirds of the gigh-expressing specimens, a heterogeneous pattern of expression was observed, indicating that certain cells within the tumor failed to express MMAC/PTEN. The combination of these results suggest that, in addition to molecular alterations affecting the gene, altered expression of MMAC/PTEN may play a significant role in the progression of GBM and patient outcome. (Cancer Research 59:1820-1824, 1999)
hajime Arimoto,F. Sano,G. Motojima,H. Yamazaki,H. Nakamura,H. Yabutani,H. Kitagawa,H. Okada,J. Arakawa,K. Kondo,K. Ohashi,K. Nagasaki,M. Yamada,M. Uno,M. Kikutake,M. Kaneko,N. Watanabe,N. Nishino,N. S 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III
The measurement of D, CII and CIII line spectral profiles and the CD band spectrum from the vicinity of a test limiter surface is performed in Heliotron J test limiter experiments. With deep insertion of the limiter, there is a localized intense region of the D, CII and CIII line intensity in the limiter surface, and the CD band spectrum is observed at this region. It is considered that the deuterium ion flux and heat load concentrate at this region and enhance carbon impurity generation.r_che
An overview of mesoscale aerosol processes, comparisons, and validation studies from DRAGON networks
Holben, Brent N.,Kim, Jhoon,Sano, Itaru,Mukai, Sonoyo,Eck, Thomas F.,Giles, David M.,Schafer, Joel S.,Sinyuk, Aliaksandr,Slutsker, Ilya,Smirnov, Alexander,Sorokin, Mikhail,Anderson, Bruce E.,Che, Huiz Copernicus GmbH 2018 Atmospheric Chemistry and Physics Vol.18 No.2
<P>Abstract. Over the past 24 years, the AErosol RObotic NETwork (AERONET) program has provided highly accurate remote-sensing characterization of aerosol optical and physical properties for an increasingly extensive geographic distribution including all continents and many oceanic island and coastal sites. The measurements and retrievals from the AERONET global network have addressed satellite and model validation needs very well, but there have been challenges in making comparisons to similar parameters from in situ surface and airborne measurements. Additionally, with improved spatial and temporal satellite remote sensing of aerosols, there is a need for higher spatial-resolution ground-based remote-sensing networks. An effort to address these needs resulted in a number of field campaign networks called Distributed Regional Aerosol Gridded Observation Networks (DRAGONs) that were designed to provide a database for in situ and remote-sensing comparison and analysis of local to mesoscale variability in aerosol properties. This paper describes the DRAGON deployments that will continue to contribute to the growing body of research related to meso- and microscale aerosol features and processes. The research presented in this special issue illustrates the diversity of topics that has resulted from the application of data from these networks. </P>
T. Charinpanitkul,W. Tanthapanichakoon,N. Sano 한국물리학회 2009 Current Applied Physics Vol.9 No.3
An idea of using pure iron and graphite electrodes was employed for synthesizing carbon nanoparticles by arc discharge in liquid nitrogen. The synthesized products consist of multiwalled carbon nanotubes (MW–CNT), carbon nanohorns (CNH), and carbon nanocapsules (CNC) with core–shell structure. Effect of metallic cathode and discharge current on product structure and yield had been experimentally investigated. Typical evidence of transmission electron microscopic images revealed that under some certain conditions of discharge in liquid nitrogen the synthesized products mainly consisted of CNCs with mean diameter of 50–400 nm. When conventional graphitic electrodes were employed, CNHs with some MW–CNTs were mainly synthesized. Meanwhile, MW–CNTs with diameter of 8–25 nm and length 150– 250 nm became less selectively synthesized as cathode deposit under the condition of discharge in liquid nitrogen with higher arc current. The production yield of carbon nanoparticles synthesized by either carbon– carbon or carbon–iron electrodes became also lower with an increase in the arc current. An idea of using pure iron and graphite electrodes was employed for synthesizing carbon nanoparticles by arc discharge in liquid nitrogen. The synthesized products consist of multiwalled carbon nanotubes (MW–CNT), carbon nanohorns (CNH), and carbon nanocapsules (CNC) with core–shell structure. Effect of metallic cathode and discharge current on product structure and yield had been experimentally investigated. Typical evidence of transmission electron microscopic images revealed that under some certain conditions of discharge in liquid nitrogen the synthesized products mainly consisted of CNCs with mean diameter of 50–400 nm. When conventional graphitic electrodes were employed, CNHs with some MW–CNTs were mainly synthesized. Meanwhile, MW–CNTs with diameter of 8–25 nm and length 150– 250 nm became less selectively synthesized as cathode deposit under the condition of discharge in liquid nitrogen with higher arc current. The production yield of carbon nanoparticles synthesized by either carbon– carbon or carbon–iron electrodes became also lower with an increase in the arc current.