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      • Changes in spatial variations of sap flow in Korean pine trees due to environmental factors and their effects on estimates of stand transpiration

        Moon, M.,Kim, T.,Park, J.,Cho, S.,Ryu, D.,Suh, S.,Kim, H. S. Springer Science + Business Media 2016 Journal of mountain science Vol.13 No.6

        <P>It is difficult to scale up measurements of the sap flux density (J(S)) for the characterization of tree or stand transpiration (E) due to spatial variations in J(S) and their temporal changes. To assess spatial variations in the sap flux density of Korean pine (Pinus koraiensis) and their effects on E estimates, we measured the J(S) using Granier-type sensors. Within trees, the J(S) decreased exponentially with the radial depth, and the J(S) of the east aspects were higher than those of the west aspects. Among trees, there was a positive relationship between J(S) and the tree diameter at breast height, and this positive relationship became stronger as the transpiration demand increased. The spatial variations that caused large errors in E estimates (i.e., up to 110.8 % when radial variation was ignored) had varied systematically with environmental factors systematic characteristics in relation to environmental factors. However, changes in these variations did not generate substantial errors in the E estimates. For our study periods, the differences in the daily E (E-D) calculated by ignoring radial, azimuthal and tree-to-tree variations and the measured ED were fairly constant, especially when the daily vapor pressure deficit (D_(D)) was higher than 0.6 kPa. These results imply that the effect of spatial variations changes on sap flow can be a minor source of error compared with spatial variations (radial, azimuthal and tree-to-tree variations) when considering E estimates.</P>

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        IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals

        Oh, J H,Cho, M-C,Kim, J-H,Lee, S Y,Kim, H J,Park, E S,Ban, J O,Kang, J-W,Lee, D-H,Shim, J-H,Han, S B,Moon, D C,Park, Y H,Yu, D-Y,Kim, J-M,Kim, S H,Yoon, D-Y,Hong, J T Nature Publishing Group 2011 Oncogene Vol.30 No.30

        <P>Several studies have shown physiological functions of interleukin (IL)-32, a novel cytokine. However, the role of IL-32 in cancer development has not been reported. In this study, we showed that IL-32γ inhibited tumor growth in IL-32γ-overexpressing transgenic mice inoculated with melanoma as well as colon tumor growth in xenograft nude mice inoculated with IL-32γ-transfected colon cancer cells (SW620). The inhibitory effect of IL-32γ on tumor growth was associated with the inhibition of constitutive activated nuclear transcription factor-κB (NF-κB) and of signal transducer and activator of transcription 3 (STAT3). The expression of antiapoptotic, cell proliferation and tumor-promoting genes (<I>bcl-2</I>, <I>X-chromosome inhibitor of apoptosis protein</I> (<I>IAP</I>), <I>cellular IAP</I> and <I>cellular FADD-like IL-1β-converting enzyme-inhibitory protein</I>, <I>cyclin D</I>), cyclin-dependent kinase 4, cycolooxygenase-2 and inducible nitric oxide synthase was decreased, whereas the expression of apoptotic target genes (<I>caspase-3</I> and <I>-9</I>, <I>bax</I>) increased. In tumor, spleen and blood, the number of cytotoxic CD8<SUP>+</SUP> T cells and CD57<SUP>+</SUP> natural killer cells and the levels of IL-10 increased, but that of tumor necrosis factor-α (TNF-α), IL-1β and IL-6 decreased. We also found that forced overexpression of IL-32γ inhibited colon cancer cell (SW620 and HCT116) growth accompanied with the inhibition of activated NF-κB and STAT3 <I>in vitro</I>. In addition, when IL-32γ was knocked down by small interfering RNA (siRNA) or neutralized with an anti-IL-32γ antibody, IL-32γ-induced colon cancer cell growth inhibition, the IL-32γ-induced decrease of TNF-α, IL-1 and IL-6 production, and the increase of IL-10 production were abolished. However, siRNA of NF-κB and STAT3 augmented IL-32γ-induced colon cancer cell growth inhibition. These findings indicate significant pathophysiological roles of IL-32γ in cancer development.</P>

      • Oils과 Carrageenan을 이용한 저지방 소세지의 저장기간에 따른 pH, 지방산 조성 및 콜레스테롤의 변화

        문점동,송또준,박구부,신택순 진주산업대학교 농업기술연구소 1996 農業技術硏究所報 Vol.9 No.-

        육제품을 많이 섭취하면 성인병을 유발한다고 믿고 있는 소비자들의 인식 변화를 유도하기 위한 저지방 소세지의 생산 가능성을 제시코자 첨가하는 지방의 량을 줄여 이에 대체물로서 물을 다량 첨가함과 동시에 3종의 oil로 일부를 대체하고 유화안정제로 카라기난을 첨가하여 low-fat sausage를 제조한 후 5℃에서 6주간 저장하면서 저장기간에 따른 pH, 지방산 조성 및 콜레스테롤의 변화에 대한 실험결과를 요약하면 다음과 같다. 1. 모든 처리구들의 pH는 저장기간이 경과함에 따라서 증가하였으며, 저지방 첨가구의 대조구인 B구의 pH에 비하여 카라기난을 첨가하지 않은 저지방 처리구들의 pH는 유의적인 차이를 나타내지 않았으나 대체로 낮은 pH를 나타내었고, 전 저장기간 동안 카라기난을 첨가한 구들이 대조구 및 다른 저지방 처리구에 비하여 높은 pH를 유지하였다(P<0.05). 2. 지방산의 조성은 대체한 oil에 의해서 oleic, linoleic, linolenic acid가 각각 증가하였으며, 저장기간에 따른 지방산 조성의 변화는 나타나지 않았다. 불포화도는 perilla, sunflower, olive의 순으로 낮았으며, 저장기간에 따른 불포화도의 변화는 나타나지 않았다. 오메가 지방산의 비율은 대체한 oil에 의해서 대조구와는 다른 비율을 나타내었으며 perilla유 대체구가 가장 높았고, 저장기간의 경과에 따른 변화는 없었다. 3. 대조구는 모든 저지방 처리구들 보다 높은 cholesterol 함량을 나타내었고, oil의 대체로 인한 cholesterol 함량의 감소가 나타났으며, 저장기간이 경과함에 따른 cholesterol함량의 변화는 없었다. This study was conducted to investigate the possibility of production of low fat sausage which was made with vegetable oils and added water to reduce back fat content in the sausage. Raw meats for the sausage were removed from the pork carcass(90∼100kg, female, 5∼7months of age) 4∼6 hours after slaughter and randomly assigned to one of eight treatments : control(back fat 30% and water 10), treatment A(back fat 15% and water 25%), treatment B(back fat 7.5%, olive oil 7.5% and water 25%), treatment C(back fat 7.5%, olive oil 7.5%, water 15% and carrageenan 0.5%), treatment D(back fat 7.5%, sunflower oil 7.5% and water 25%), treatment E(back fat 7.5%, sunflower oil 7.5%, water 25% and carrageenan 0.5%), treatment F(back fat 7.5%, perilla oil 7.5% and water 15%) and treatment G(back fat 7.5%, perilla oil 7.5%, water 25% and carrageenan 0.5%). The sausage samples were stored at 5±1℃. The pH, fatty acid and cholesterol were analyzed for over a period of times(0, 2, 4, 6 weeks) The results obtained were summarized as follows : The pH of all treatments was increased with the storage period. The pH values of sausages with carrageenan were lower than that of treatment A but there were no significant differences between the sausages and treatment A. The pH of sausages with carrageenan was higher than those of control and other(P<0.05). The composition of fatty acids of sausages with olive, sunflower and perilla oil was changed, so treatment B and c, D and E and F and G had higher oleic acid, linoleic acid and linolenic acid, respectively. There was no difference with the storage period. The ratio of unsaturated to saturated fatty acids of sausages was affected by oil type and there was no difference with the storage period. The ratio of n-3 to n-6 fatty acids of sausages was different from that of control, and that of treatment F and G, both of which perilla oil was added, was higher than those of others. There was no difference with the storage period. The cholesterol content of control was higher than those of others, and that of low fat sausages was decreased. There was no difference with the storage period.

      • KCI등재
      • SCISCIESCOPUS

        Vitamin D-binding protein interacts with Aβ and suppresses Aβ-mediated pathology

        Moon, M,Song, H,Hong, H J,Nam, D W,Cha, M-Y,Oh, M S,Yu, J,Ryu, H,Mook-Jung, I Macmillan Publishers Limited 2013 CELL DEATH AND DIFFERENTIATION Vol.20 No.4

        The level of vitamin D-binding protein (DBP) is increased in the cerebrospinal fluid of patients with Alzheimer’s disease (AD), suggesting a relationship with its pathogenesis. In this study, we investigated whether and how DBP is related to AD using several different approaches. A pull-down assay and a surface plasmon resonance binding assay indicated direct interactions between purified DBP and amyloid beta (Aβ), which was confirmed in the brain of AD patients and transgenic AD model mice by immunoprecipitation assay and immunohistochemical double-staining method. Moreover, atomic force microscopic examination revealed that DBP reduced Aβ aggregation in vitro. DBP also prevented Aβ-mediated death in cultured mouse hippocampal HT22 cell line. Finally, DBP decreased Aβ-induced synaptic loss in the hippocampus and rescued memory deficits in mice after injection of Aβ into the lateral ventricle. These results provide converging evidence that DBP attenuates the harmful effects of Aβ by a direct interaction, and suggest that DBP is a promising therapeutic agent for the treatment of AD.

      • HWE(Hot Wall Epitaxy)에 의한 ZnIn_2S_4 박막 성장과 광전도 특성

        홍광준,이관교,정준우,정경아,방진주,장현규,문종대,김혜숙 조선대학교 기초과학연구소 1999 自然科學硏究 Vol.22 No.1

        HWE 방법에 의해 ZnIn_2S_4 박막을 Si(00) 기판 위에 성장시켰다. 증발원과 기판의 온도를 각각 610℃, 450℃로 하여 성장시킨 ZnIn_2S_4 박막의 이중 결정 X-선 요동곡선(DCRC)의 반폭치(FWHM)값이 245 arcsec로 가장 작았다. Van der Pauw 방법으로 Hall 효과를 측정하여 운반자농도의 1n n 대 1/T에서 구한 활성화에너지는 0.17eV로 측정되었다. Hall 이동도의 온도 의존성은 30K에서 100K까지는 불순물산란에 기인하고, 100K에서 293K까지는 격자산란에 기인한것으로 고찰되었다. 광전도셀의 특성으로 spectral response, 최대 허용소비전력(MAPD), 광전류와 암전류(pc/dc)의 비 및 응답시간을 측정하였다. S 증기분위기에서 열처리한 광전도 셀의 경우, 감도(??)는 0.99, pc/dc은 1.37x10^7, 그리고 최대 허용소비전력(MAPD)은 336mW, 오름시간(rise time)은 9ms, 내림시간(decay time)은 9.8ms로 가장 좋은 광전도 특성을 얻었다. The ZnIn_2S_4 thin films were grown on the Si(100) wafers by a hot wall epitaxy method(HWE). The source and substrate temperature are 610℃ and 450℃ respectively. The crystalline structure of epilayers was investigated by double crystal X-ray diffraction(DCXD). Hall effect on the sample was measured by the van der Pauw method and studied on the carrier density and mobility dependence on temperature. From Hall data, the mobility was increased in the temperature range 30K to 100K by impurity scattering and decreased in the temperature range 100K to 293K by the lattice scattering. In order to explore the applicability as a photoconductive cell, we measured the sensitivity(??), the ratio of photocurrent to darkcurrent(pc/dc), maximum allowable power dissipation(MAPD), spectral response and response time. The results indicated that the photoconductive characteristic were the best for the samples annealed in S vapor compare with in Zn, In, air and vacuum vapour. Then we obtained the sensitivity of 0.99, the value of pc/dc of 1.37x10^7, the MAPD of 336mW, and the rise and decay time of 9ms and 9.8ms, respectively.

      • 하이브리드 볼륨 PTV(VPTV)

        도덕희(D.H. Doh),조효제(H.J. Jo),조경래(K.R. Cho),문경록(K.R. Moon),이재민(J.M. Lee),황태규(T.G. Hwang) 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.11

        A new 3D-PTV algorithm (a Volume PTV) based upon a hybrid fitness function has been constructed. A coherency fitness function is introduced using the information of space and time to sort out the correct particle pairs between the two camera images. The measurement system consists of two-high-definition-cameras(1k × 1k), a Nd-Yag laser and a host computer. The developed algorithm has been employed to investigate the flow features of the cylinder wake. The Reynolds numbers with the cylinder diameter (d=10㎜) are 360, 720, 900 and 1260. Two-dimensional displacements of the particles of each camera’s image and neighbouring constraints were introduced to reduce the calculation loads. More than 10,000 instantaneous 3D vectors have been obtained by the constructed algorithm. The constructed algorithm could recover more than 80~90% of the particle numbers in the image.

      • KCI등재

        DRUM impactor를 이용한 대기 입자상 물질 중 원소성분의 입경분포 특성 : 제주도 고산지역의 2002년 봄철(3.29 ~ 5.30) 측정 연구 Measurements in Springtime 2002

        한진석,문광주,류성윤,안준영,공부주,홍유덕,김영준 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.4

        Size-segregated measurements of aerosol composition using X-stage DRUM impactor are used to determine the transport of natural and anthropogenic aerosols at Gosan site from 29 March to 30 May in 2002. Separation of ambient aerosols by DRUM impactor offers many advantages over other standard filtration techniques. Some of the most important advantages are the ability to segregate into details by particle size, to better preserve chemical integrity since the air stream doesn't pass through the deposit, to collect samples as a function of time, and to have a wide variety of impaction surfaces available to match analytical needs. Although the transport of Yellow sand is a well-known phenomenon in springtime, the result of measurement shows that not only soil dust but also anthropogenic aerosols, including sulfur, enriched trace metals such as Pb, Ni, Zn, Cu, Cr, As, Se, Hr, are transported to Gosan in springtime. This study combines the size- and time- resolved aerosol composition measurements with isentropic, backward air-mass trajectories in order to identify some potential source regions of anthropogenic aerosols. As a result, during the NYS period, the average concentration of PM_(10) was 46 ㎍/㎥. Si, Al, S, Fe, Cl, K, Ca were higher than 1,000 ㎍/㎥ and Ti was about 100 ㎍/㎥. The concentrations of Zn, Mn, Cu, Pb, Br, Rb, V, Cr, Ni, As, Se ranged between 1 and 70 ㎍/㎥. More than 50% of typical soil elements, such as Al, Si, Fe, Ca, Ti, Cr, Cu, Br, were distributed in a coarse particle range (5.0 ∼ 12μm). In other hand, anthropogenic pollutants, such as S, N, Vi, were mainly distributed in a fine particle range (0.09 ∼ 0.56μm). During the YS period, PM_(10) increased about 8 times than NYS period, and main soil elements, such as Al, Si, S, K, V, Mn, Fe also doubled in coarse particle range (1.15 ∼ 12μm). But Zn, As, Pb, Cu and Se, which distributed in the fine aerosols (0.09 ∼0.56μm), were on the same level with or decreased than NYS period. Finally, except the YS period, coarse particles (2.5 ∼ 12μm) arc inferred to be influenced by soil, coal combustion, waste incineration, ferrous and nonferrous sources through similar pathways with Yellow Sand. But line particles have different sources, such as coal combustion, gasoline vehicle, biomass burning, oil or coal combustion, nonferrous and ferrous metal sources, which are transported from China, Korea peninsula and local sources.

      • Synthesis and photovoltaic characterization of D/A structure compound based on N-substituted phenothiazine and benzothiadiazole

        Yun, D.H.,Yoo, H.S.,Heo, S.W.,Song, H.J.,Moon, D.K.,Woo, J.W.,Park, Y.S. Korean Society of Industrial and Engineering Chemi 2013 Journal of industrial and engineering chemistry Vol.19 No.2

        In this study, poly [(N-10'-dodecyl-phenothizin-3,7-ylene)-alt-(2,2'-bithiophen-5-yl)] (P1) and poly [(N-10'-dodecyl-phenothiazin-3,7-ylene)-alt-(5',6'-dioctyloxy-benzothiadiazole-bithiophene)] (P2) were synthesized by Suzuki coupling reaction. Optical and electrochemical characteristics of the synthesized polymers, P1 and P2, were then analyzed, indicating that their wavelength of maximum absorption was 453nm and 533nm, respectively, and their band-gap was 1.93eV and 1.74eV, respectively. The maximum power conversion efficiency (PCE) of organic photovoltaic cells created by using P1 and P2 were 0.74% (P1:PC<SUB>71</SUB>BM=1:4,w/w) and 1.00% (P2:PC<SUB>71</SUB>BM=1:3,w/w), respectively, and the short circuit current density (J<SUB>SC</SUB>), fill factor (FF), and open circuit voltage (V<SUB>OC</SUB>) of the device were 3.5mA/cm<SUP>2</SUP>, 31.8%, and 0.68V, respectively, for P1 and 3.9mA/cm<SUP>2</SUP>, 32.7%, and 0.78V, respectively, for P2.

      • 나노크기의 은 촉매를 이용한 프로필렌의 산화반응

        정정조,문동주,김영철,박남국,신재순 한국공업화학회 2002 응용화학 Vol.6 No.2

        Epoxidation of propylene to propylene oxide over the modified silver catalyst was investigated in an atmospheric fixed bed flow reactor. Promoted catalysts were prepared by deposition-precipitation, and characterized by X-ray diffraction(XRD) and N_2 Physisorption. Silver catalysts modified NaCl, BaCl_2 and CaCl_2 were higher selectivity than those modified LiCl and MgCl_2. It was found that l0wt.% NaCl/Ag catalyst was showed higher selectivity than the other catalysts under tested reaction conditions. It can be interpreted that the AgCl formed in the preparation process may be changed the property of silver catalyst, which is effective for propylene epoxidation.

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