한국인 인슐린 비의존형 당뇨병 및 이차성 당뇨병 환자에서 글루코키나제 유전자 변이

남재현(Jae Hyun Nam),이현철(Hyun Chul Lee),김연의(Youn Euy Kim),권석호(Suk Ho Kwon),윤용석(Yong Suk Yoon),박석원(Suk Won Park),원영준(Young Jun Won),차봉수(Bong Su Cha),송영득(Young Duk Song),이은직(Eun Jig Lee),임승길(Sung Kil Lim) 대한내과학회 1998 대한내과학회지 Vol.54 No.6

N/A Objectives: Mutations in the glucokinase (GCK) gene are considered a possible cause of maturity-onset diabetes of the young. The purpose of this study was to evaluate the contribution of this gene to the development of non insulin dependent diabetes mellitus (NIDDM), gestational diabetes mellitus (GDM) and post-renal transplantation diabetes mellitus (PTDM). Method: Identification of GCK mutation was attempted on 39 NIDDM patients, 2 GDM patients and 58 selected renal allograft recipients with PTDM and 45 normal controls. The exons in the GCK gene were examined by polymerase chain reaction (PCR), followed by analysis of single-stranded DNA conformational polymorphism (SSCP). The abnormal bands were also confirmed by DNA sequencing analysis. The exons of affected family members were also investigated for mutations of the GCK gene. Results: Two of the 58 PTDM patients (3.4%) were found to have CKK mutations. One had the mutation on exon 5 and the other on intron 7. One control subject had the mutation on intmn 9. The mutation of exon 5 was identified as a substitution of CCT (proline) for CTT (leucine) at codon 164, which has not ever reported before. The family members of the PFDM patient with mutation of exon 5 were analyzed by PCR followed by SSCP, and two of them revealed the same mutation. The abnormal band on the SSCP analysis of exon 7 was identified as the insertion of base C/T at the 39th nucleotide in intron 7. Two family members of this patients also had same band on SSCP. The one mutation of 45 normal controls was CT located at the 8th nucleotide in intron 9, which was a common polymorphism. Conclusion: We found GCK mutations in subjects with PTDM and we speculate that these mutations may be one of the contributing cause of PTDM.

Pulsed field gel electrophoresis(PFGE)를 이용한 Yersinia entirocolitica의 특성조사

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

Pulsed field gel electrophoresis(PFGE) was conducted compare the Not I digested genomic profile of one hundred Yersinia entirocolitica. This method was very efficient for subtyping pathogenic and non-pathogenic isolates of Yersinia entirocolitica. Generally, pulsotype was more closer to serotype than biotype. But pulsotype of 3/O:5 was more related to biotype than serotype. For epidemiological purpose, the comparison of relationship among biotype. serotype, RAPD(random amplitication of polymorphic DNA) and pulsotype of PFGE should be studied as powerful tools.

지능형 정속주행 제어시스템 개발

임영도,설재훈,한창훈,김승철,박종오,이준탁,방석원 東亞大學校 附設 情報通信硏究所 1998 情報通信硏究所論文誌 Vol.6 No.1

This paper describes an intelligent cruise control system for automobile. With the remarkable numericalincrease of automobiles on the roal, the optimized traffic flow control using the cruise control is one of the very important traffic problems to overcome the limitation of an existing road capacity. Based onthis idea that minimize the fuel cost and teh air pollution, and accept a driver's needs for driving, we have developed an intelligent cruise control system for vehicle. This proposed intelligent fuzzy cruise controller was successfully implemented using the fuzzy algorithm, the i80c196 μ-controller board and the throttle valve actuator. The field test results on an linear road was introduced.

Random Amplification of Polymorphic DNA(RAPD)를 이용한 Yersinia enterocolitica의 PCR Fingerprinting비교

임순영,윤석권 동덕여자대학교 생활과학연구소 2006 생활과학연구 Vol.11 No.-

The lamer single primer was used to generate random amplification of polymorphic DNA(RAPD) profiles by polymerase chain reaction(PCR) for 100 strains of Y. enterocolitica from various sources. The RAPD pattern within same serotype was devided into different subtypes and also RAPD pattern of different serotypes showed same RAPD type. Regardless of serotype for Y. enterocolitica, DNA fingerprinting bands of non-pathogenic strains were a few in number and small in size but those of pathogenic were reversed. Every serotype showed unique RAPD pattern. therefore it is possible to discriminate within Y. enterocolitica strains. Showing some strains no band or a few, RAPD is effective method to subtype the strains. If RAPD was utilized with serotyping and biotyping, it should be powerful tool to devide Y. enterocolitica strains for epidem iological purpose.

공업화부재의 생산/운반/양중관리를 위한 정보가시화 시스템 개발에 관한 연구

임형철,송영석,김창덕,송성진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

Recently, The construction field in the urban area is short of working space and securing processing place because it is surrounded by adjacent buildings and nearby roads and have difficulties in rising labor costs. The insufficient space causes problems of interference and conflicts in transporting materials and working at the site. Therefore, Construction Manager find many alternative method and select industrialized method. The objective of this paper is to develop and give a method of information visualization system for manufacturing, delivering and lifting these materials in construction project stakeholders, using tools visualizing informations. The tools supports to stakeholders so many informations in material manufacturing, delivering, lifting in construction site. That is, order information, manufacture information in factory, sending information, carrying information, unloading and lifting in Site, and so on. Case studies are performed to evaluate the feasibility and applicability of the proposed method.

디지털 공제방사선영상의 기하학적 보정에 관한 연구

임숙영,고광준 대한구강악안면방사선학회 2001 Imaging Science in Dentistry Vol.31 No.1

Purpose : To develop a new subtraction program for registering digital periapical images based on the correspondence of anatomic structures. Materials and Methods : The digital periapical images were obtained by Digora system with Rinn XCP equipment after translation of 1-16 mm, and rotation of 2-20°at the premolar and molar areas of the human dried mandible. The new subtraction program, NIH Image program and Emago/Advanced program were compared by the peak-signal-to noise ratio(PSNR). Results : The new subtraction program was superior to NIH Images program and Emago/Advanced program up to 16 mm translation and horizontal angulation up to 4°. Conclusion : The new subtraction program can be used for subtracting digital periapical images.(Korean J Oral Maxillofac Radiol 2001;31:23-34)

아시아 경기대회의 서구화와 그 반성

임영무,안희숙 한국체육사학회 2001 체육사학회지 Vol.7 No.-

We together had a chance to think over the subject of Asian Games. It may looks issuance of regionalism or nationalism against the current on of globalization however, in order to find the ways for the further development of the spirit of Asian Games, it is believed that it's time to open the discussion on it. We also did put efforts to search the next deploying goals of the Asian Games, while reviewing both positive and negative aspects of the Games through the chronological investigation of Asian Games history, and researching the situational aspects of pre-modern and modern Asian sports. Thinking over the two aspects, positive and negative viewpoints, of the general effects of the Asian Games to Asian sports, the 4 positive effects of Asian Games may be pointed out ; ①that Asian Games affected to solidify the generalization of the culture of sports attributed to bringing the perception change about sports in Asian people, ② that it also contributed to spreading the Asia-origin sports to the world ③ that it established the infrastructure of sports in Asia through changing the game holding place among Asian countries, and ④ that it provided the good chances to exchange the national cultures among Asian countries. On the other hand the negative aspects may be mentioned ; ①that the loss of Asian traditional sports culture could be ascribed to the fact that the western sports has been the mainstream in Asian Games ② that the magnitude expansion strategy of the Games limited the number of Game hosting cities, so that only a few cities could hold the Game thus far, ③ that the original spirit of Asian Games has been impaired by making political use of Asian Games like the case of Olympic Games, and ④ that the deployment of diversity of world sports cultures into Asia was not enough Directions that Asian Games in 21st century is moving forward can be ; ① to study the Games operation centered on Asian traditional sports, ② to put efforts on magnitude optimization of the Game in size ③ seek the ways exclude the various non-sports ideologies in order for Asian Games to be the untained place of Asian harmony and advancement. To act Asian Games as a role to promote the Asian peace and goodwill among the Asian countries, the hosting country of the Games needs to establish the (hosting) policies and procedures toward of reconciling the different opinions among the member countries and enhancing the friendships, and to implement it. All participants to the international Games are requested to contribute to both the goodwill of Asian countries and world peace by the sportsmanship, the reciprocal cooperative competition.

穀類 및 豆類의 腐敗程度와 化學的 成分間의 相互關係

林順英,尹錫權 同德女子大學校 1996 同大論叢 Vol.26 No.1

Various cereals and legumes as well as rice have been used as food in this country. The growth rate of microorganism in those food was different by different food sources. This difference was supposed to be different nutrient contents that are composed of food. Therefore, four kind of cereals (rice, barley, millet and sorghum) and legumes (soybean, small red bean, mungbean and cowpea) were heated at 121℃ for 20 minutes and then the growth rate of microorganisms was measured at four hour intervals unitl 32 hours after heating. Also changes in pH, free sugar, ammonium nitrogen, free amino acid and minerals of cereals and legumes were investigated also relationship with growth rate of microorganisms were estimated. The growth rate of microorganism in legumes was faster than cereals. Exceptionally number of microorganism in sorghum was alsmost same as those in legumes. The pH of barley was lowest compared with other cereals and legumes. Free sugars contents in legumes right after steaming were much higher than those of cereals, and after 12 hours, those in all samples was increased however, after 24 hours free sugars were decreased. High correlation between number of microorganism cells and free sugar were noticed that the content of free sugar affected the growth rate of microorganisms. The early ammonium content in sample supposed to be affected on early growth of microorganism because the ammonium content steaming showed a high significant correlation with the number of micrrorganisms. Free sugar content of legumes higher than cereals. Small red bean was the highest while rice was the lowest. Rice, soybean and mungbean after 24 hour showed a little change during incubation while millet was decreased and the others were increased. Total free amino acid content in testing materials showed high correlation with the number of microorganisms at 4, 12 and 16 hours after incubation. In all samples, the contents of potassium and phosphorous were higher than other minerals. All mineral contents of legumes were higher than cereals. Relationship between number of microorganisms at 4, 12 and 16 hours after steaming and total mineral contents in samples showed significant linear correlation.

전전자 교환기에서의 과부하제어에 관한 연구

林錫鳩,張殷永,金元厚 한국항공대학교 1991 論文集 Vol.29 No.-

TDX-10 및 EWSD 기종의 과부하 제어방식을 검토한 후 프로세서 점유율 측면에서 성능이 향상된 제어방식을 3가지로 분류하여 제안하며, 각각을 가정된 모델에 따라 시뮬레이션을 수행하여 성능평가를 행하였다. 그 결과 TDX-10L방식을 제외한 제안한 방식은 과부하 상태에서도 시스템 설계용량인 90%의 프로세서 점유율로 유지함을 확인하였다. The performance analysis of proposed three overload control methods is conducted to present the more optimal than methods using in conventional TDX-10 and EWSD by simulation with the assumed model. From simulation result, the two methods except TDX-10L are satisfied with 90% of the designed processor engineered capacity.

한국상장기업의 所有構造와 資本調達政策에 관한 연구

임석필,송영열 단국대학교 산업연구소 1997 산업연구 Vol.20 No.-