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페녹시계 제초제 MCPA를 분해하는 토양세균의 분리 및 특성 연구
김영진,차민석,오계헌,고준경,김영훈 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.1
A pure culture that can utilize 4-chloro-2-methylphenoxyacetic acid(MCPA) as a sole carbon and energy source was isolated from soil samples. Initially, clear zone formation on thin-layered MCPA agar plates was observed around spot inoculum of the isolate. As the results of various physiological and biochemical tests, the isolate was identified as Pseudomonas aeruginosa. The bacterium was able to degrade MCPA(300㎎/L) completely within 7 days of incubation as determined by UV-spectrophotometric analysis.
Effect of Pineapple Protease on the Characteristics of Protein Fibers
Koh Joon-Seok,Kang Sang-Mo,Kim Soo-Jin,Cha Min-Kyung,Kwon Yoon-Jung The Korean Fiber Society 2006 Fibers and polymers Vol.7 No.2
A pineapple protease, bromelain, was used to improve the dyeing properties of protein fibers such as wool and silk. The optimal condition for the activity of the pineapple protease was about $60^{\circ}C$ at pH 7. The wool and silk were treated with the protease extracted from a pineapple and the K/S values of the dyed wool and silk were measured using a spectrophotometer in order to compare the dye uptake. The protease treatment enhanced the dyeing properties of protein fibers without severe changes in mechanical properties. The surface appearances of protease-treated fibers were observed by microscopy.
Koh, Young Jun,Koh, Bong Ihn,Kim, Honsoul,Joo, Hyung Joon,Jin, Ho Kyoung,Jeon, Jongwook,Choi, Chulhee,Lee, Dong Hun,Chung, Jin Ho,Cho, Chung-Hyun,Park, Won Seok,Ryu, Ji-Kan,Suh, Jun Kyu,Koh, Gou Young Ovid Technologies Wolters Kluwer -American Heart A 2011 Arteriosclerosis, thrombosis, and vascular biology Vol.31 No.5
Dyebath Reuse in Dyeing of Nylon Microfiber Non-woven Fabric with 1:2 Metal Complex Dyes
Koh, Joon-Seok,Kim, Yong-Geol,Kim, Jae-Pil The Korean Fiber Society 2001 Fibers and polymers Vol.2 No.1
Dyebath used for metal complex dyeing of nylon microfiber was recycled to reduce the overall amounts of metal complex dyeing effluents. Instead of discharging the dyebath after each dyeing cycle, the residual dyebath was analyzed spectrophotometrically and reconstituted to the required concentration of dyes and auxiliaries. Dyebaths were reused eight times and the CIELAB coordinates of dyed samples were measured after each recycling. Color difference($\Delta$E*) between the sample dyed in the fresh bath and that from reused dyebath was maintained below 1.5. The levelness and fastness of dyed fabrics from recycled dyebath were not impaired either. Chromium content of each recycled dyebath was similar to that of the first residual dyebath.
Hwang, Hyeon Seok,Park, Mahn-Won,Yoon, Hye Eun,Chang, Yoon Kyung,Yang, Chul Woo,Kim, Suk Young,Cho, Jung Sun,Kim, Chan Joon,Park, Gyung-Min,Park, Chul-Soo,Choi, Yun-Seok,Koh, Yoon-Seok,Lee, Jong Min,S S. Karger AG 2014 American journal of nephrology Vol.40 No.4
<P>Abstract</P><P><B><I>Background/Aims:</I></B> Atrial fibrillation (AF) often coexists with acute myocardial infarction (AMI), and chronic kidney disease (CKD) is a major risk for AMI. However, the combined impact of CKD and AF on the mortality and morbidity in AMI population has not been determined. <B><I>Methods:</I></B> Between January 2004 and December 2009, a total of 4,738 AMI patients were enrolled prospectively. Patients were divided into four groups according to the combined status of CKD and AF. The primary endpoint was a combination of 5-year major adverse cardiac and cerebrovascular events (MACCE). <B><I>Results:</I></B> The prevalence of AF was significantly higher in CKD patients than in non-CKD patients (6.76 vs. 3.31%, p < 0.001). The highest cumulative event rate of MACCE and death was observed in patients with both CKD and AF (68.5 and 64.0%), respectively. In multivariable analyses, compared with patients with neither AF nor CKD, hazard ratios (HR) for composite of MACCE were 1.66 (95% CI, 1.14-2.41), 1.24 (95% CI, 1.06-1.46), and 2.10 (95% CI, 1.42-3.13) for patients with AF only, those with CKD only, and those with both CKD and AF, respectively (p for interaction = 0.935). Patients with both CKD and AF had a greatest risk for all-cause mortality (HR 2.54; 95% CI, 1.60-4.53), and the significant synergistic interaction was observed between CKD and AF (p for interaction = 0.015). <B><I>Conclusion:</I></B> The combined effect of AF and CKD on the risk of MACCE after an AMI is stronger than any separate condition, and it confers a synergistic effect on the all-cause mortality risk.</P><P>© 2014 S. Karger AG, Basel</P>
( Joon Seong Ahn ),( Dong Hyun Sinn ),( Geum Youn Gwak ),( Jong Man Kim ),( Choon Hyuck Kwon ),( Jae Won Joh ),( Yong Han Paik ),( Moon Seok Choi ),( Joon Hyeok Lee ),( Kwang Cheol Koh ),( Seung Woon 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: The degree of steatosis of donated liver is one of decisive factors that determine graft function in recipient and recovery of remnant liver in living donor. Hence, the assessment of hepatic steatosis is a critical element to judge donor compatibility. We evaluated the prevalence and predictors of steatosis among liver donors who had no evidence of fatty liver on screening ultrasonography (US-negative). Methods: Degree of hepatic steatosis was reviewed for 492 US-negative liver donors (age: 30.1 ± 9.9, male: 301 (61.2%)). Clinical and laboratory variables were analyzed to identify predictors for steatosis. Results: The prevalence of severe (≥ 60%), moderate (30 ∼ 59%), mild (5 ∼ 29%) and no steatosis (<5%) were 0.6% (3/492), 10.8% (53/492), 39.6% (195/492) and 49.0% (241/492), respectively. In multivariate analysis, BMI [kg/㎡, OR (95% CI): 1.15, p = 0.021] and serum triglyceride level [mg/dl, OR (95% CI): 1.01, p = 0.004] were independent factors associated with steatosis ≥ 30%. The optimal cutoff for steatosis ≥ 30% by receiver operator curve analysis was 23 kg/㎡ for BMI and 88 mg/dl for triglyceride. Steatosis ≥ 30% was significantly more prevalent for liver-donors with high BMI (15.2% vs. 9.0% for BMI ≥ 23 vs. < 23 kg/m2, p = 0.034) and with high serum triglyceride level (15.5% vs. 8.7% for triglyceride ≥ 88 vs. < 88 mg/dl, p = 0.021). Based on these two parameters, the prevalence of steatosis ≥ 30% was 6.6%, 13.0% and 28.6% for none, one and both risk factors, respectively. Conclusions: About a half of US-negative liver donors have steatosis ≥ mild degree and one-tenth of them has ≥ moderate degree. USG assessment is not sufficient to exclude donors with significant steatosis especially for those with high BMI and triglyceride level, and thus, pre-operative liver biopsy should be positively considered for them.
흰쥐 앞뇌중격부의 콜린성신경세포에서 Nerve Growth Factor 및 Galanin 의 공존
고기석,장병준,조익현 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-
Mammalian forebrain septal area, which is closely concerned in learning and memory, contains a lot of cholinergic neurons. It has been well-known that these neurons have high levels of some neurosubstances including acetylcholine. It has been reported that galanin as a neuromodulator/neurotransmitter and a nerve growth factor(NGF) as a neurotrophic factor are densely localized in rat forebrain septal area. However, the precise localization, co-localization and correlation between these neurosubstances have not been clearly elucidated yet. To identify the co-localization of these substances in rat forebrain septal area, immunohistochemistry using antibodies to choline acetyltransferase(ChAT), NGF and galanin has been accomplished on serial paraffin-sections of forebrain septal area. 1. High concentrations of ChAT, NGF and galanin positive neurons were observed in the medial septal nucleus(MS) and the diagonal bands of Broca(DBB) in the basal forebrain. 2. Approximately 80.6% of cholinergic neurons were NGF positive, and 78.0% of the neurons were galanin positive, and 71.6% of the cells exhibited positive reaction for both substances, in the forebrain septal area. 3. Some of ChAT, NGF and galanin positive neurons were distributed individually in the forebrain septal area. Based on the results mentioned above, it could be concluded that NGF and galanin were co-localized in most cholinergic neurons of the forebrain septal area. It seems that there are functional reciprocal between these substances in the forebrain septal area.
Low-level laser therapy in immune-mediated skin disease: a narrative review
Joon Seok,Young Gue Koh,김범준 대한의학레이저학회 2022 MEDICAL LASERS Vol.11 No.4
Low-level laser therapy (LLLT) is now widely used in dermatology due to the relatively low risk of adverse events. LLLT can modulate mito chondria levels and affect various cell types, such as keratinocytes, lymphocytes, and fibroblasts, leading to its use in various treatments, such as pain reduction, tissue regeneration, and for conditions like inflammatory acne. This study explores the mechanism of action of LLLT and reviews its possible roles as a potential treatment option for common immune-mediated skin diseases, such as alopecia areata, psoriasis, and atopic dermatitis.