Fertility and prognosis assessment between bleomycin/etoposide/cisplatin and paclitaxel/carboplatin chemotherapy regimens in the conservative treatment of malignant ovarian germ cell tumors: a multicenter and retrospective study

Ran Chu,Penglin Liu,Jingying Chen,Xiaodong Cheng,Kezhen Li,Yanci Che,Jianliu Wang,Li Li,Xi Zhang,Shu Yao,Li Song,Ying Zhao,Changzhen Huang,Ying Xue,Xiyu Pan,Junting Li,Zhongshao Chen,Jie Jiang,Beihua 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.2

Objective: To evaluate the impact of bleomycin/etoposide/cisplatin (BEP) and paclitaxel/carboplatin (PC) chemotherapy regimens on the fertility and prognostic outcomes in malignant ovarian germ cell tumor (MOGCT) patients who underwent fertility-sparing surgery (FSS). Methods: A propensity score matching algorithm was performed between the BEP and PC groups. The χ2 test and the Kaplan-Meier method were used to compare the fertility outcome, disease-free survival (DFS) and overall survival (OS). The Cox proportional hazards regression analysis was used to identify risk factor of DFS. Results: We included 213 patients, 185 (86.9%) underwent BEP chemotherapy, and 28 (13.1%) underwent PC chemotherapy. The median age was 22 years (range, 8–44 years), and the median follow-up period was 63 months (range, 2–191 months). Fifty-one (29.3%) patients had a pregnancy plan, and 35 (85.4%) delivered successfully. In the before and after propensity score matching cohorts, there were no significant differences in spontaneous abortion, selective termination of pregnancy, during-pregnancy status, and live birth between the BEP and PC groups (p>0.05). Fourteen (6.6%) patients experienced recurrence, including 11 (5.9%) in the BEP group and 3 (10.7%) in the PC group. Four (1.9%) patients in the BEP group died. Kaplan-Meier analysis revealed no significant differences in DFS (p=0.328) and OS (p=0.446) between the BEP and PC groups, and the same survival results were observed in the after matching cohort. Conclusion: The PC regimen is as safe as the BEP regimen for MOGCT patients with fertility preservation treatment, and no differences were observed in fertility and clinical prognosis.

Effects of water-to-cement ratio, curing method and fiber on the autogenous shrinkage of early-age concrete

Weilun Wang,Junting Li,Wenjun Peng 한양대학교 세라믹연구소 2019 Journal of Ceramic Processing Research Vol.20 No.S1

This study used a temperature stress test machine (TSTM) to study the effects of the water-to-cement (w/c) ratio, curingmethod and the content of polyvinyl alcohol (PVA) fiber on the autogenous shrinkage of high-performance concrete (HPC). The experimental values were compared with theoretical values obtained from four sets of autogenous shrinkage models tocompare model accuracy. The study results indicated the followings: (1) the autogenous shrinkage value of concrete increasedwith decreases in the w/c ratio. (2) The natural and semi-adiabatic curing conditions caused the specimens to form a low- anda high-temperature rise, respectively. The higher the temperature rise, the larger the stable value of the autogenous shrinkage. (3) Among the CEB-FIP, EN-1992, RILEM and Tazawa models, the Tazawa model demonstrated the highest degree ofaccuracy. (4) PVA fiber contents of 0.75% and 0.25% had the most significant and minimal autogenous shrinkages,respectively.

CFD Numerical Simulation of Wind Field and Vehicle Aerodynamic Characteristics on Truss Bridge Deck under Crosswind

Mingjin Zhang,Jinxiang Zhang,Junting Long,Yongle Li,Yulin Zou,Dianguo Yin 대한토목학회 2022 KSCE Journal of Civil Engineering Vol.26 No.12

Due to the complexity and changeability of the wind field in deep-cut gorges, the vehicles on the bridge deck are easily affected by a strong crosswind. Thus, to accurately evaluate the wind field characteristics of a suspension bridge deck, the wind profiles of wind speed and angle of attack (AoA) and the vehicle aerodynamic parameters were investigated by the CFD. The results show that the shape of wind speed profile is mainly controlled by the AoA but less affected by the Reynolds number. The main girder's shielding effect can accelerate the local wind field, and the closer to the windward lane, the less the interference; thus, a suitable location of measuring points to represent the incoming flow is found. Furthermore, the equivalent wind speed based on the equivalent side force is generally larger than the value based on the rolling moment, and the responding value is greatly affected by the AoA. In addition, the vortex is a time-dependent phenomenon, the averaged flow field produced less force in the wake, but the high local wind speed variations may affect the traffic unfavorably. The results provide an essential reference significance for studying the local wind field characteristics of the bridge deck.

Emission properties of sequentially deposited ultrathin CH3NH3PbI3/MoS2 heterostructures

Shao Ziyi,Xiao Junting,Guo Xiao,You Siwen,Zhang Yangyang,Li Mingjun,Song Fei,Zhou Conghua,Xie Haipeng,Gao Yongli,Sun Jiatao,Huang Han 한국물리학회 2022 Current Applied Physics Vol.36 No.-

Hybrid organic-inorganic perovskite materials have obtained considerable attention due to their exotic optoelectronic properties and extraordinarily high performance in photovoltaic devices. Herein, we successively converted the ultrathin PbI2/MoS2 into the CH3NH3PbI3/MoS2 heterostructures via CH3NH3I vapor processing. Atomic force microscopy (AFM)、Scanning electron microscopy (SEM) and X-ray photoemission spectroscopy (XPS) measurements prove the high-quality of the converted CH3NH3PbI3/MoS2. Both MoS2 and CH3NH3PbI3 related photoluminescence (PL) intensity quenching in CH3NH3PbI3/MoS2 implies a Type-II energy level alignment at the interface. Temperature-dependent PL measurements show that the emission peak position shifting trend of CH3NH3PbI3 is opposite to that of MoS2 (traditional semiconductors) due to the thermal expansion and electron-phonon coupling effects. The CH3NH3PbI3/TMDC heterostructures are useful in fabricating innovative devices for wider optoelectronic applications.

Epitaxial growth of <010>-oriented MoO2 nanorods on m-sapphire

Jinxin Liu,Jiao Shi,Di Wu,Xiaoming Zheng,Fengming Chen,Junting Xiao,Youzhen Li,Fei Song,Yongli Gao,Han Huang 한국물리학회 2020 Current Applied Physics Vol.20 No.10

Molybdenum dioxide (MoO2) materials have attracted considerable interests due to their superduper properties and potential applications, relating to the growth directions and exposed surfaces. Here, we reported as the substrate changes from c-to m-sapphire, the growth direction of epitaxial MoO2 nanorods via an atmospheric pressure chemical vapor deposition approach changes along from <001> to <010> of bulk monoclinic MoO2 accompanied by exposing different surfaces. Optical microscopy (OM), Raman spectroscopy, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), cross-sectional scanning electron microscopy (SEM), highresolution transmission electron microscopy (HRTEM) and selected area electron diffraction (SAED) measurements reveal these MoO2 nanorods are epitaxially grown on m-sapphire substrates with the orientation of MoO2 (101)//sapphire (1010) and MoO2 <010> in line with sapphire <0001>. The electrical conductivity significantly depends on the crystallographic direction of MoO2 nanorods. The method to control the growth directions of 1D MoO2 nanorods has potential applications in nanoelectronic devices.

Crystallization Toughening of Fe-Based Amorphous Alloys Under Strain–Heat Coupling Effect

Wei Zhao,Jiacheng Yu,Mindong Hu,Honglei Hu,Junting Luo,Gong Li 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.1

The crystallization toughening of Fe-based amorphous alloys under strain–heat coupling effect was studied. This effectinvolved annealing crystallization along with uniform plastic deformation under three-direction compressive stress. Resultsshowed that the Fe-based amorphous alloys subjected to strain–heat coupling action had greater toughening effect than thosesubjected to single low-temperature annealing. The difference was due to the change in morphology of the precipitated crystalphase and the substantial amount of free volume introduced into an amorphous matrix through uniform plastic deformation,which was conducive to the proliferation of shear bands. However, excessive plastic deformation led to direct fracture ofmaterials after elastic deformation.