AUTOMA TIC ACQUISITION OF TRANSLATION EQUIVALENCES FROM BILINGUAL CORPUS

Chun-xiαng Zhang,Tie-jun Zhao,Sheng Li 한국어정보학회 2005 국제학술대회 Vol.2005 No.08

The Impacts and Countermeasures of Japan's Proposal to Release Nuclear-Contaminated Water into the Sea on Neighboring Countries

Xuexi Zhang(Xuexi Zhang),Xi Chen(Xi Chen) 아시아사회과학학회 2023 Jornal of Asia Social Science Vol.10 No.1

Since 2020, the Japanese government has made great efforts to promote the discharge of nuclear-polluted water from the Fukushima nuclear power plant. Although it is strongly opposed by the Japanese and neighboring countries, the Japanese government still puts economic benefits first and does not fully consider the biological and chemical hazards that may be caused by the discharge of nuclear-polluted water into the sea, the impact on people's health, or whether it will pose a threat to Japan's offshore and neighboring countries' marine safety and food safety. As always, it is an obvious violation of the United Nations Convention on the Law of the Sea to choose the simplest, lowest-cost, and most irresponsible way to discharge nuclear-polluted water into the sea, which needs to be highly valued by neighboring countries and even all countries around the Pacific Ocean, and actively take measures to avoid the harm caused by Japan's nuclear-polluted water discharged into the sea to neighboring countries. To solve the current problems, it is necessary for the United Nations to actively play the role of central mediator and for neighboring countries to jointly create international public opinion on the harm caused by the discharge of nuclear-polluted water into the sea. At the same time, it is also necessary to call on non-governmental environmental protection organizations to protest and continuously increase internal pressure in Japan. In addition, the active resistance to importation of the fish resources from Japan and the reduction in the number of tourists to Japan are also important measures to prevent the Japanese government from dumping nuclear-polluted water. Therefore, actively calling on the Japanese government to cancel or terminate the dumping of nuclear-polluted water into the sea is not only the greatest protection of the lives and property of people in Japan and neighboring countries, but a responsible expression of ensuring that the world's maritime security is not threatened.

Magnesium isoglycyrrhizinate inhibits L-type Ca2+ channels, Ca2+ transients, and contractility but not hERG K+ channels

Yue Lin,Yuanyuan Zhang,Qiongtao Song,Tao Song,Xue Han,Ying Zhang,Xuan Zhang,Xi Chu,Fenghua Zhang,Li Chu,Jianping Zhang 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.10

To explore the cardiovascular protective effectsof Magnesium isoglycyrrhizinate (MI), especially theunderlying cellular mechanisms related to L-type calciumchannels and myocardial contractility, and to examine theeffects of MI on hERG K? current expressed in HEK293cells. We used the whole-cell patch clamp technique,video-based edge detection and dual excitation fluorescencephotomultiplier systems to explore the effect of MIon L-type Ca2? currents (ICa-L) and cell contraction in ratcardiomyocytes. We also examined the rapidly activatingdelayed rectifier potassium current (IKr) expressed inHEK293 cells using a perforated patch clamp. MI inhibitedICa-L in a dose-dependent manner, with a half-maximalinhibitory concentration (IC50) of 0.22 mg/ml, and themaximal inhibitory effect was 61.10 ± 0.59%. MI at aconcentration of 0.3 mg/ml reduced cell shortening by24.12 ± 3.97% and the peak value of the Ca2? transient by36.54 ± 4.96%. MI had no significant influence on hERGK? channels expressed in HEK293 cells at all testpotentials. MI exerts protective effects on the heart via theinhibition of ICa-L and cell shortening in rat cardiomyocytes. However, MI had no significant influence on IKr;thus, MI may exert cardioprotective effects without causingdrug-induced long QT syndrome.

Design-Oriented Stability of Outer Voltage Loop in Capacitor Current Controlled Buck Converters

Zhang, Xi,Zhang, Zhongwei,Bao, Bocheng,Bao, Han,Wu, Zhimin,Yao, Kaiwen,Wu, Jing The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.4

Due to the inherent feedforward of load current, capacitor current (CC) control shows a fast transient response that makes it suitable for the power supplies used in various portable electronic devices. However, considering the effect of the outer voltage loop, the stable range of the duty-cycle is significantly diminished in CC controlled buck converters. To investigate the stability effect of the outer voltage loop on buck converters, a CC controlled buck converter with a proportion-integral (PI) compensator is taken as an example, and its second-order discrete-time model is established. Based on this model, the instability caused by the duty-cycle is discussed with consideration of the outer voltage loop. Then the dynamical effects of the feedback gain of the PI compensator and the equivalent series resistance (ESR) of the output capacitor on the CC controlled buck converter with a PI compensator are studied. Furthermore, the design-oriented closed-loop stability criterion is derived. Finally, PSIM simulations and experimental results are supplied to verify the theoretical analyses.

Biosynthesis of adipic acid in metabolically engineered Saccharomyces cerevisiae

Zhang Xi,Liu Yingli,Wang Jing,Zhao Yunying,Deng Yu 한국미생물학회 2020 The journal of microbiology Vol.58 No.12

Adipic Acid (AA) is a valued platform chemical compound, which can be used as a precursor of nylon-6,6. Due to the generation of an enormous amount of nitric oxide metabolites and the growing depletion of oil resources as a result of AA production from a mixture of cyclohexanol and cyclohexanone, the microbial methods for synthesizing AA have attracted significant attention. Of the several AA-producing pathways, the reverse adipate degradation pathway in Thermobifida fusca (Tfu RADP) is reported to be the most efficient, which has been confirmed in Escherichia coli. In this study, the heterologous Tfu RADP was constructed for producing AA in S. cerevisiae by co-expressing genes of Tfu_ 0875, Tfu_2399, Tfu_0067, Tfu_1647, Tfu_2576, and Tfu_ 2576. The AA titer combined with biomass, cofactors and other by-products was all determined after fermentation. During batch fermentation in a shake flask, the maximum AA titer was 3.83 mg/L, while the titer increased to 10.09 mg/L during fed-batch fermentation in a 5-L bioreactor after fermentation modification.

Improved Design of High School Girl's Summer Uniform Based on Style Theory

Zhang, Ling-Xi,Wang, Jian-Ping The Korean Society of Costume 2015 International journal of costume and fashion Vol.15 No.2

By means of statistical analysis and module concept, this paper investigated the current situation of high school girl's uniform and put forward its improved design and database establishment. Combined with the survey data, the future design direction and trend of the high school girls' uniform were proposed. By using modular design concept, the uniform is divided into five modules, and a style database has been built. Meanwhile, the parametric pattern database has been completed by using garment CAD system, based on the style database above, which has 42,336 possibilities to assemble a pair of school uniform. Combining with digital sewing techniques and by using computerized embroidery machine, the personalized design of high school girl's summer uniform has been realized. And two simulated case have been given for examples to prove its feasibility. The idea of modular design and parametric design method proposed in this study offer references for establishing the modular design database and parametric pattern database for other types of school uniform and are of relatively high practical and theoretical value.

PRI: A Practical Reputation-based Incentive Scheme for Delay Tolerant Networks

( Xi Zhang ),( Xiaofei Wang ),( Anna Liu ),( Quan Zhang ),( Chaojing Tang ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.4

Delay tolerant networks (DTNs) characterized by the lack of guaranteed end-to-end paths exploit opportunistic data forwarding mechanism, which depends on the hypothesis that nodes are willing to store, carry, and forward the in-transit messages in an opportunistic way. However, this hypothesis might easily be violated by the presence of selfish nodes constrained with energy, bandwidth, and processing power. To address this problem, we propose a practical reputation-based incentive scheme, named PRI, to stimulate honest forwarding and discipline selfish behavior. A novel concept of successful forwarding credential and an observation protocol are presented to cope with the detection of nodes` behavior, and a reputation model is proposed to determine egoistic individuals. The simulation results demonstrate the effectiveness and practicality of our proposal.

A Small Bipedal Trans-Scale Precision Positioning Stage Based on Inertial Stick-Slip Driving

Xi Zhang,Bowen Zhong,Bin Liu,Ziqi Jin,Zhenhua Wang,Lining Sun 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.22 No.3

The small size and high flexibility of the mobile platform is widely used in many fields such as electron scanning microscope (SEM), but the mobile platform still adopts the structure of guide rail at present and has the problem of large volume and poor flexibility, which cannot meet the requirements of SEM for small cavity. Therefore, this paper proposes a small bipedal trans-scale precision positioning stage based on the inertial stick-slip driving to achieve small size and high flexibility. The mobile platform consists of two piezoelectric actuators, a frame structure, two bottom plates, two pre-tightening screws, and magnets, and the volume is 15 mm × 10 mm × 9.5 mm. To investigate the locomotion characteristics of the mobile platform, a prototype is manufactured, and a series of experiments are carried out. The experimental results show that its linear motion velocity can reach 3.553 mm/s and its angular velocity can reach 462.72mrad/s, which means that the mobile platform has good motion performance.

Recombinant Human Thioredoxin-1 Protects Macrophages from Oxidized Low-Density Lipoprotein-Induced Foam Cell Formation and Cell Apoptosis

Zhang, Hui,Liu, Qi,Lin, Jia-Le,Wang, Yu,Zhang, Ruo-Xi,Hou, Jing-Bo,Yu, Bo The Korean Society of Applied Pharmacology 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.2

Oxidized low-density lipoprotein (ox-LDL)-induced macrophage foam cell formation and apoptosis play critical roles in the pathogenesis of atherosclerosis. Thioredoxin-1 (Trx) is an antioxidant that potently protects various cells from oxidative stress-induced cell death. However, the protective effect of Trx on ox-LDL-induced macrophage foam cell formation and apoptosis has not been studied. This study aims to investigate the effect of recombinant human Trx (rhTrx) on ox-LDL-stimulated RAW264.7 macrophages and elucidate the possible mechanisms. RhTrx significantly inhibited ox-LDL-induced cholesterol accumulation and apoptosis in RAW264.7 macrophages. RhTrx also suppressed the ox-LDL-induced overproduction of lectin-like oxidized LDL receptor (LOX-1), Bax and activated caspase-3, but it increased the expression of Bcl-2. In addition, rhTrx markedly inhibited the ox-LDL-induced production of intracellular reactive oxygen species (ROS) and phosphorylation of p38 mitogen-activated protein kinases (MAPK). Furthermore, anisomycin (a p38 MAPK activator) abolished the protective effect of rhTrx on ox-LDL-stimulated RAW264.7 cells, and SB203580 (a p38 MAPK inhibitor) exerted a similar effect as rhTrx. Collectively, these findings indicate that rhTrx suppresses ox-LDL-stimulated foam cell formation and macrophage apoptosis by inhibiting ROS generation, p38 MAPK activation and LOX-1 expression. Therefore, we propose that rhTrx has therapeutic potential in the prevention and treatment of atherosclerosis.

Soy Protein Supplementation Reduces Clinical Indices in Type 2 Diabetes and Metabolic Syndrome

Xi-Mei Zhang,Yun-Bo Zhang,Mei-Hua Chi 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.3

Purpose: Clinical trials have studied the use of soy protein for treating type 2 diabetes (T2D) and metabolic syndrome (MS). The purpose of this study was to outline evidence on the effects of soy protein supplementation on clinical indices in T2D and MS subjects by performing a meta-analysis of randomized controlled trials (RCTs). Materials and Methods: We searched PubMed, EMBASE, and Cochrane databases up to March 2015 for RCTs. Pooled estimates and 95% confidence intervals (CIs) were calculated by the fixed-and-random-effects model. A total of eleven studies with eleven clinical variables met the inclusion criteria. Results: The meta-analysis showed that fasting plasma glucose (FPG) [weighted mean difference (WMD), -0.207; 95% CI, -0.374 to -0.040; p=0.015], fasting serum insulin (FSI) (WMD, -0.292; 95% CI, -0.496 to -0.088; p=0.005), homeostasis model of assessmentfor insulin resistance index (HOMA-IR) (WMD, -0.346; 95% CI, -0.570 to -0.123; p=0.002), diastolic blood pressure (DBP) (WMD, -0.230; 95% CI, -0.441 to -0.019; p=0.033), low-density lipoprotein cholesterol (LDL-C) (WMD, -0.304; 95% CI, -0.461 to -0.148; p=0.000), total cholesterol (TC) (WMD, -0.386; 95% CI, -0.548 to -0.225; p=0.000), and C-reactive protein (CRP) (WMD, -0.510; 95% CI, -0.722 to -0.299; p=0.000) are significant reduced with soy protein supplementation, compared with a placebo control group, in T2D and MS patients. Furthermore, soy protein supplementation for longer duration (≥6 mo) significantly reducedFPG, LDL-C, and CRP, while that for a shorter duration (<6 mo) significantly reduced FSI and HOMA-IR. Conclusion: Soy protein supplementation could be beneficial for FPG, FSI, HOMA-IR, DBP, LDL-C, TC, and CRP control in plasma.