http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Prediction of Travel Time of Fire Service using Kriging and Weighted-sum Technique
Yoonha Lee(Yoonha Lee),Minseok Kim(Minseok Kim),Jisoo Lee(Jisoo Lee) 한국화재소방학회 2022 International Journal of Fire Science and Engineer Vol.36 No.2
The accessibility of city fire services is an important indicator for evaluating fire services and optimizing fire resource allocation. For firefighting, rescue, and first-aid activities, it is recommended that the time from fire vehicles leaving the garage to arrive at the scene is less than 5 minutes. Therefore, the travel time of fire services is one of the main concerns for many researchers. This study assumes that changing the urban environment affects the travel time of fire services. Therefore, in this study, weights were applied over the years to predict the travel time of fire service by using the kriging technique. As a result of the case study, temporal factors (elapsed year, term of travel time, and time spent) did not significantly affect travel time prediction accuracy using the kriging technique. As observed in previous studies, it is confirmed that the prediction accuracy is high because it is less affected by traffic-related factors at short travel distances. The results of this study contribute to the development of spatial analysis techniques to improve the accuracy of travel-time prediction.
FASHION THERAPY RESEARCH TRENDS AND PROPOSAL FOR ENHANCING HAPPINESS
Sae-eun Lee,Yuri Lee,Jisoo Ha,Joeun Lee 글로벌지식마케팅경영학회 2015 Global Fashion Management Conference Vol.2015 No.06
This study proposes the use of fashion as a tool of psychotherapy for individuals feeling social and psychological pressure due to society’s emphasis on appearances. The concept of fashion therapy was re-established, and theories (cognitive behavioral therapy, person-centered therapy, solution-focused brief therapy) founded on art therapy were introduced. Based on past research, this study developed a process for fashion therapy.
Lee, Changkyu,Seo, Jisoo,Hwang, Ha Shin,Thao, Le Quang,Lee, Seunghyun,Lee, Eun Seong,Lee, Eun Hee,Choi, Han-Gon,Youn, Yu Seok Elsevier 2016 BIOMEDICINE AND PHARMACOTHERAPY Vol.78 No.-
<P><B>Abstract</B></P> <P>Pulmonary fibrosis is a chronic lung disease characterized by inflammation and collagen deposition, with an estimated mortality rate exceeding 70%. Here, we evaluated the therapeutic effectiveness of inhaled tacrolimus-loaded chitosan-coated poly(lactic-<I>co</I>-glycolic acid) nanoparticles (chitosan TAC PLGA-NPs) in a bleomycin-induced pulmonary fibrosis mouse model. Chitosan TAC PLGA-NPs were fabricated using an o/w emulsification diffusion method, and uncoated TAC PLGA-NPs and chitosan TAC PLGA-NPs were spherical with approximate diameters of 320 and 441nm, respectively. The zeta potential of chitosan TAC PLGA-NPs (+13.6mV) was increased significantly by chitosan-coating versus uncoated TAC PLGA-NPs (−28.3mV). The incorporation efficiency of tacrolimus was 37.7%, and the tacrolimus was gradually released until about 5day. Direct inhalation of chitosan TAC PLGA-NPs (TAC 180μg/mouse) twice a week produced marked anti-fibrotic efficacy in mice with bleomycin-induced pulmonary fibrosis, which was much better than the efficacy resulting from daily oral administration (TAC 300μg/mouse) on the basis of hematoxylin/eosin and Masson’s trichrome staining assessments. Imaging of lung deposition showed that chitosan TAC PLGA-NPs were located well in the lungs and gradually faded over 96h. The pulmonary delivery of tacrolimus could be therapeutically efficacious for treating pulmonary fibrosis. TAC-loaded PLGA nanoparticles should be considered to be an efficient sustained-release type inhalation system that reduces administration frequency and relevant side effects.</P>
Facile synthesis of metal hydroxide nanoplates and their application as lithium-ion battery anodes
Lee, Dong Jun,Yu, Seung-Ho,Lee, Hyeon Seok,Jin, Aihua,Lee, Jisoo,Lee, Ji Eun,Sung, Yung-Eun,Hyeon, Taeghwan The Royal Society of Chemistry 2017 Journal of materials chemistry. A, Materials for e Vol.5 No.18
Jiwon Lee,Kibeom Jeon,Taekha Lee,Jisoo Lee,Miyoung Kim,Han-Sung Kim,Young Kyung Lee,Hee Jung Kang 대한임상검사정도관리협회 2020 Journal of Laboratory Medicine And Quality Assuran Vol.42 No.3
Background: In this study, we aim to examine the effects of pre-analytical factors such as specimen type (serum or plasma), collection and storage conditions, and time, on the results of chemiluminescence immunoassay. Methods: Blood samples were collected from 10 individuals and aliquoted into two sets of K3-ethylenediaminetetraacetic acid (EDTA) and serumseparating tubes (SST) each, for plasma and serum collection, respectively. For all the samples, one set of tubes was centrifuged within 1 hour and other set was centrifuged after 4 hours, followed by cell separation. Chemiluminescence assay was performed for adrenocorticotropic hormone (ACTH), parathyroid hormone (PTH), osteocalcin, C-telopeptide, and insulin at 0, 6, 24, and 48 hours after centrifugation; all the samples were assayed in duplicate. The samples were stored at 4℃ before the assay. Results: The results obtained showed that the levels detected in plasmas were more consistent and stable as compared to serum. After a 6-hour storage at 4℃, a significant decrease was observed in the levels of ACTH and osteocalcin in plasma and serum; whereas, PTH and C-telopeptide levels were stable in plasma but decreased significantly in serum. Insulin levels in serum showed a decrease after a 6-hour storage while the levels in plasma were found to be stable until 24-hour storage. Serum samples separated after 4 hours showed a significant decrease in all hormone levels, while C-telopeptide and insulin levels were stable in plasma samples separated after 4 hours. Conclusions: The results were found to be more stable in plasma samples from K3-EDTA tubes as compared to serum samples from SST in the measurement of unstable biological analytes. These results suggest that K3- EDTA tubes are preferable in the specimen collection for assaying biological analytes.
( Jisoo Park ),( Yeon Joo Lee ),( Se Joong Kim ),( Jong Sun Park ),( Ho Il Yoon ),( Jae Ho Lee ),( Choon Taek Lee ),( Young Jae Cho ) 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
Excessive dynamic airway collapse (EDAC) is a disease entity of excessive reduction of the central airway diameter during exhalation, without cartilage collapse. An 80-year-old female presented with generalized edema and dyspnea at our hospital. The patient was in a state of acute decompensated heart failure due to pneumonia with respiratory failure. We accordingly managed the patient with renal replacement therapy, mechanical ventilation and antibiotics. Bronchoscopy confirmed the diagnosis of EDAC. We scheduled extubation after the improvement of pneumonia and heart condition. However, extubation failure occurred due to hypercapnic respiratory failure with poor expectoration. Her EDAC was improved in response to high flow nasal oxygen therapy (HFNOT). Subsequently, the patient was stabilized and transferred to the general ward. HFNOT, which generates physiologic positive end expiratory pressure (PEEP) effects, could be an alternative and effective management of EDAC. Further research and clinical trials are needed to demonstrate the therapeutic effect of HFNOT on EDAC.
Lee, Seon Jin,Kim, Da Yeon,Yun, Jisoo,Choi, Sung Hyun,Jung, Seok Yun,Kang, Songhwa,Park, Ji Hye,Kim, Yeon Ju,Ha, Jong Seong,Ji, Seung Taek,Jang, Woong Bi,Lee, Dong Hyung,Lee, Dongjun,Kwon, Sang-Mo Hindawi 2018 Stem cells international Vol.2018 No.-
<P>Cross talks between the renin-angiotensin system (RAS), sympathetic nervous system, and vascular homeostasis are tightly coordinated in hypertension. Angiotensin II (Ang II), a key factor in RAS, when abnormally activated, affects the number and bioactivity of circulating human endothelial progenitor cells (hEPCs) in hypertensive patients. In this study, we investigated how the augmentation of Ang II regulates adrenergic receptor-mediated signaling and angiogenic bioactivities of hEPCs. Interestingly, the short-term treatment of hEPCs with Ang II drastically attenuated the expression of beta-2 adrenergic receptor (ADRB2), but did not alter the expression of beta-1 adrenergic receptor (ADRB1) and Ang II type 1 receptor (AT1R). EPC functional assay clearly demonstrated that the treatment with ADRB2 agonists significantly increased EPC bioactivities including cell proliferation, migration, and tube formation abilities. However, EPC bioactivities were decreased dramatically when treated with Ang II. Importantly, the attenuation of EPC bioactivities by Ang II was restored by treatment with an AT1R antagonist (telmisartan; TERT). We found that AT1R binds to ADRB2 in physiological conditions, but this binding is significantly decreased in the presence of Ang II. Furthermore, TERT, an Ang II-AT1R interaction blocker, restored the interaction between AT1R and ADRB2, suggesting that Ang II might induce the dysfunction of EPCs via downregulation of ADRB2, and an AT1R blocker could prevent Ang II-mediated ADRB2 depletion in EPCs. Taken together, our report provides novel insights into potential therapeutic approaches for hypertension-related cardiovascular diseases.</P>