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다발성 연조직 종괴를 동반한 급성 림프구성 백혈병의 증례 보고
장정용,허경회,이원진,허민석,이삼선,최순철 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.2
A 15-year-old patient, who had been diagnosed and treated as Burkitt cell type acute lymphoblastic leukemia (ALLL3) already, visited our department. He complained of gingival enlargement and loosening teeth 1 month ago. The clinical examination revealed anterior open bite, gingival enlargement, and nontender swelling particularly in molar regions of both jaws. Deep periodontal pockets and severe mobility was shown on most of the teeth. The panoramic radiographs showed severe bone destruction and extrusion of the molars. The contrast enhanced CT showed multiple enhanced mass and bone marrow obliteration in both jaws. Chemotherapy was done and the swelling was subsided at 1 month later. In conclusion, radiologic findings of leukemia with soft tissue mass, known as chloroma or granulocytic sarcoma, mimic those of lymphoma, so blood test may be needed for the final diagnosis.
증례 : 순환기; 감염성 심내막염이 발생한 젊은 여성에서 동반된 스트레스성 심근병증
허정원 ( Jeong Won Heo ),정철민 ( Chul Min Jung ),박현선 ( Hyun Sun Park ),최장원 ( Jang Won Choi ),오원섭 ( Won Sub Oh ),조병렬 ( Byung Ryul Cho ),류동열 ( Dong Ryeol Ryu ) 대한내과학회 2014 대한내과학회지 Vol.86 No.3
Takotsubo cardiomyopathy is a clinical syndrome characterized by chest pain, transient left ventricular dysfunction, and specific electrocardiographic changes induced by physical or emotional stress. We describe a rare case of this syndrome associated with acute mitral valve bacterial endocarditis in a young female.
장하은 ( Ha-eun Jang ),장지민 ( Ji-min Jang ),허민희 ( Min-hee Heo ),노진원 ( Jin-won Noh ),김장묵 ( Jang-mook Kim ) 대한보건협회 2021 대한보건연구 Vol.47 No.3
목적 : 본 연구에서는 인구사회학적 요인을 통제하여 안전벨트 착용에 따른 음주운전 경험 여부의 관계를 파악하고, 연구대상자의 인구사회학적 특성에 따른 음주운전 경험 여부의 영향요인을 확인하고자 하였다. 방법 : 제7기 국민건강영양조사 3차 년도 자료를 활용하여, 만 19세 이상인 설문응답자 중 음주운전과 안전벨트 관련 문항에 응답한 3,312명을 최종 분석 대상으로 선정하였다. 결과 : 평상시 안전벨트 착용 여부와 최근 1년 내 음주운전 여부는 통계적으로 유의한 관련성을 보였으며, 평상시에 안전벨트를 항상 착용하는 사람에 비해 그렇지 않은 사람의 음주운전 경험률이 더 높은 것으로 나타났다. 자동차 음주운전의 영향요인은 성별, 결혼상태, 교육수준, 경제활동 상태, 거주지역으로 나타났다. 결론 : 안전벨트의 착용이 자동차 음주운전과 유의한 관계를 지녔음을 알 수 있으며, 본 연구 결과가 차량 운전자의 안전의식 향상 및 교통안전 정책 수립의 기초자료로 활용되기를 기대한다. Objective : The purpose of this study is to investigate the correlation between the experience of drunk driving and seatbelt usage controlling socio-demographic factors. Methods : A cross-sectional analysis was performed with 3,312 participants among those who answered the data of the third year of the 7th National Health Nutrition Survey. Results : It was identified participants with lower seatbelt usage were more likely to have a drunk driving experience compared to those higher seatbelt usage. Conclusion : We revealed that seatbelt usage has a significant relationship with drunk driving. These results are expected to be utilized for improving safety consciousness of drivers and establishing traffic safety policies.
Son, Sangkeun,Hong, Young-Soo,Jang, Mina,Heo, Kyung Taek,Lee, Byeongsan,Jang, Jun-Pil,Kim, Jong-Won,Ryoo, In-Ja,Kim, Won-Gon,Ko, Sung-Kyun,Kim, Bo Yeon,Jang, Jae-Hyuk,Ahn, Jong Seog American Chemical Society and American Society of 2017 Journal of natural products Vol.80 No.11
<P>Analysis of the genome sequence of <I>Streptomyces</I> sp. KCB13F003 showed the presence of a cryptic gene cluster encoding flavin-dependent halogenase and nonribosomal peptide synthetase. Pleiotropic approaches using multiple culture media followed by LC-MS-guided isolation and spectroscopic analysis enabled the identification of two new chlorinated cyclic hexapeptides, ulleungmycins A and B (<B>1</B> and <B>2</B>). Their structures, including absolute configurations, were determined by 1D and 2D NMR techniques, advanced Marfey’s analysis, and GITC derivatization. The new peptides, featuring unusual amino acids 5-chloro-<SMALL>l</SMALL>-tryptophan and <SMALL>d</SMALL>-homoleucine, exhibited moderate antibacterial activities against Gram-positive pathogenic bacteria including methicillin-resistant and quinolone-resistant <I>Staphylococcus aureus</I>.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jnprdf/2017/jnprdf.2017.80.issue-11/acs.jnatprod.7b00660/production/images/medium/np-2017-00660j_0005.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/np7b00660'>ACS Electronic Supporting Info</A></P>