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        • KCI등재

          한국어판 미국 국립안연구센터 시각기능설문지 25의 타당성 및 신뢰도 연구

          허장원,윤희성,신재필,문상웅,진희승,곽형우,Jang Won Heo,Hee Seong Yoon,Jae Pil Shin,Sang Woong Moon,Hee Seung Chin,Hyung Woo Kwak 대한안과학회 2010 대한안과학회지 Vol.51 No.10

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Purpose: To translate and evaluate the reliability and validity of the Korean version of the National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25). Methods: Two bilingual ophthalmologists independently translated the original English version of the NEI-VFQ-25 into written Korean. A panel of the Korean Retina Society reviewed the translations to form a single reconciled forward translation of the Korean version of the NEI-VFQ-25. Another ophthalmologist back-translated this first draft into English. Both the first draft and back-translated draft were edited by a professional translator. To evaluate the correlation and validity, results between the original NEI-VFQ-25 and the Korean version, completed by the bilingual participants, were compared. Results: The Korean version of the National Eye Institute Visual Functioning Questionnaire-25 was developed by translation, back-translation, and expert supervision. Results from 23 bilingual participants between the original NEI-VFQ-25 and the Korean version were compared and showed statistically significant correlation, with a Spearman’s correlation coefficient of 0.4 or greater. The Kolmogorov-Smirnov test results showed no statistically significant differences between the two questionnaires. Conclusions: Translation and validation of the Korean version of the NEI-VFQ-25 was achieved. J Korean Ophthalmol Soc 2010;51(10):1354-1367

        • KCI등재후보

          과립형성 및 성형방법에 따른 SOFC 음극의 미세구조 및 특성

          허장원,이종호,황진하,문주호,Heo, Jang-Won,Lee, Jong-Ho,Hwang, Jin-Ha,Moon, Joo-Ho 한국전기화학회 2003 한국전기화학회지 Vol.6 No.1

          음극지지형 고체산화물 연료전지의 전극성분은 연료전지 성능의 주된 감쇄요인으로 지적되고 있는 분극저항을 줄이기 위해 높은 전기전도도와 가스투과도등이 요구되어지고 있다. 본 연구에서는 SOFC음극의 성능에 영향을 주는 음극의 미세구조, 특히 음극의 기공구조를 다르게 형성시키기 위해 두 가지 서로 다른 과립형성 방법을 이용하여 음극을 제조하고 이에 따라 기판의 기공구조가 어떻게 바뀌는지 또 그로 인해 기판의 미세구조 및 전기전도도가 어떠한 영향을 받는지 관찰하였다 또한 미세구조에 대한 정량적인 화상분석을 통해 기판의 미세구조적인 인자들과 전극특성간의 상관관계를 분석하였다. It is well known that the anode substrate of anode-supported type SOFC should have high electrical conductivity and high gas permeability to minimize the polarization loss of the cell performance during operation. In this study, we made anode substrates of SOFC with two different methods, which gave different anode microstructures, especially different pore structures with each other. We performed electrical and microstructural characterization of Ni/YSZ cermet anode via extensive measurements of its electrical conductivity and gas permeability combined with adequate image analysis based on quantitative stereological theory

        • KCI등재

          실험적으로 유발된 굴절 부등이 양안시에 미치는 영향

          허장원(Jang Won Heo),유경원(Kyung Won Yoo) 대한안과학회 1999 대한안과학회지 Vol.40 No.12

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

        • KCI등재
        • KCI등재
        • KCI등재

          냉동치료가 망막색소상피세포의 국소유착분자의 발현에 미치는 영향

          이준교,허장원,정흠,Jun-Gyo Lee,Jang Won Heo,Hum Chung 대한안과학회 2005 대한안과학회지 Vol.46 No.2

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Purpose: In the pathogenesis of proliferative vitreoretinopathy (PVR), retinal pigment epithelial (RPE) cells do not undergo apoptosis after separation from the basement membrane. In order to investigate the mechanism by which RPE cells resist apoptosis in PVR, the expression of focal adhesion kinase after cryotherapy was studied. Methods: After lensectomy and vitrectomy was performed on rabbit eyes, a retinal tear was created. Cryotherapy was applied to the tear site one week after the tear creation. Rabbits were sacrificed at 1, 4 and 7 days after the tear formation and 30 minutes, 1, 4, 7, 9, 21 days after cryotherapy. Eyes were stained with anti-focal adhesion kinase (FAK) antibody. Results: Expression of FAK increased after the tear formation and remained increased until 21days after cryotherapy. Conclusions: These data show that creation of a retinal tear and cryotherapy increases FAK expression and may contribute to resistance to apoptosis.

        • KCI등재

          괴사성 공막염으로 안내염이 발생하여 유리체절제술 및 영구양막이식술로 치료한 1예 보고

          이상윤,허장원,위원량,이진학,김미금,Sang Yoon Lee,Jang Won Heo,Won Ryang Wee,Jin Hak Lee,Mee Kum Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.1

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Purpose: To report a case of a patient with infectious endophthalmitis associated with necrotizing scleritis that was treated with pars plana vitrectomy and permanent amniotic membrane transplantation. Case summary: A 76-year-old man with pain and visual loss in the right eye was diagnosed with infectious endophthalmitis and necrotizing scleritis. The visual acuity in the right eye was hand motion, and the slit lamp examination showed infection of the conjunctiva and sclera, corneal edema, hypopyon, and necrosis of nasal sclera. An intravitreal antibiotic injection was given, and Pseudomonas aeruginosa was cultured in vitreous fluid. Two days afterward, when vitrectomy was performed, leakage from the scleral microperforation and necrosis of the peripheral cornea was observed. Thus, a 10-layered permanent amniotic membrane transplantation was performed. The patient was given topical antibiotics and steroids, oral prednisolone, and cyclophosphamide postoperatively. After 74 days, endophthalmitis was remitted, and scleritis was well controlled. His visual acuity recovered to 20/40. Conclusions: Infectious endophthalmitis due to scleral microperforation by necrotizing scleritis can be treated effectively with vitrectomy combined with permanent amniotic membrane transplantation. J Korean Ophthalmol Soc 2011;52(1):97-102

        • KCI등재

          안내 섬모에 의한 안내염

          김미진,허장원,정흠,Mijin Kim,Jang Won Heo,Hum Chung 대한안과학회 2010 대한안과학회지 Vol.51 No.6

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Purpose: To report a case of intraocular cilium revealed by diagnostic vitrectomy in a case of stubborn uveitis that was unresponsive to steroid therapy. Case summary: A 39-year-old man was referred to our hospital due to decreased vision in his right eye that started two months prior to presentation. He had previously been treated for a diagnosis of iridocyclitis. The patient’s history revealed a blunt trauma to the right eye while wearing glasses after which he developed a microhyphema and was treated for traumatic iritis at another clinic 3 months ago. He was treated with topical and oral steroids after being diagnosed with iridocyclitis and had recently been prescribed additional oral cyclosporine because his condition had not improved. Ocular examination revealed inflammatory cells in the anterior chamber and vitreous cavity with hand motion vision. Ultrasonography revealed a hazy vitreous cavity but the retina was flat. Diagnostic vitrectomy with intravitreal antibiotic injection was performed and an intraocular foreign body presumed as a cilium was detected without an entrance wound on the exterior or interior surface of the eye. After removal of the foreign body, the patient’s vision was completely recovered. Conclusions: In cases of chronic uveitis that do not respond to immunosuppressive treatment without a clearly definable cause, diagnostic vitrectomy should be considered, keeping in mind the possibility of intraocular foreign body. J Korean Ophthalmol Soc 2010;51(6):904-907

        • KCI등재

          맥락막신생혈관의 광역학치료후 발생한 장액성 망막박리

          김신우,정흠,허장원,Cinoo Kim,Hum Chung,Jang Won Heo 대한안과학회 2007 대한안과학회지 Vol.48 No.10

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Purpose: To quantify the development and resolution of serous retinal detachment in patients with choroidal neovascularization (CNV) following photodynamic therapy (PDT). Methods: Six eyes of five patients who developed serous retinal detachment two days after PDT were included in this study. Retinal thickness was measured by optical coherence tomography (OCT) before PDT, and at two days, seven days, and three weeks after PDT. The number of PDT and the greatest linear dimension (GLD) of the CNV lesion were recorded. Results: Serous retinal detachment was demonstrated on OCT at two days after PDT. Retinal elevation increased significantly from 313.2 m before PDT to 640.7 m two days after PDT (P<0.01); elevation and decreased to 303.2 m seven days after PDT, and decreased to 223.4 m three weeks after PDT. The mean number of PDT treatments 2.0 (range: 1~3), and the mean GLD before PDT was 3122.81275.9 m. Conclusions: This study suggest that serous retinal detachment in patients with CNV may develop following PDT but may also resolve spontaneously seven days after PDT.

        • KCI등재

          열공망막박리에서 자가플라스민을 이용한 유리체절제술의 효과

          박채린,이선호,허장원,정흠,Chaerin Park,Sun Ho Lee,Jang Won Heo,Hum Chung 대한안과학회 2011 대한안과학회지 Vol.52 No.7

          '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

          Purpose: To evaluate the efficacy and complication of autologous plasmin (AP) injected before vitrectomy for rhegmatogenous retinal detachment (RRD). Methods: Intravitreal AP injection (0.2 ml) was performed on the eyes without posterior vitreous detachment (PVD) 20 minutes before the vitrectomy for RRD. The extent of PVD was evaluated intraoperatively. Surgical PVD induction was performed and the ease of the procedure was graded. The extent of PVD, ease of PVD induction, and complications (including incidence of iatrogenic retinal break) were compared to those of the control eyes. In order to evaluate complications and measure activated partial thromboplastin time, a microbial culture of injected AP was performed and the rate of postoperative intraocular hemorrhage was investigated. Change in visual acuity and the rate of retinal reattachment were compared in order to evaluate the long-term surgical outcome. Results: The extent of PVD was greater in the AP group than in the control group, and vitreal separation was facilitated by intravitreal AP injection. However, ease of PVD induction and frequency of iatrogenic retinal break found were not significantly different between cases and controls. Neither postoperative intraocular hemorrhage nor systemic coagulation abnormality occurred. Postoperative endophthalmitis and positive microbial culture of the AP solution were also not reported. There was no significant difference in the change in visual acuity and the rate of retinal reattachment between the two groups. Conclusions: Intravitreal AP injection can facilitate vitrectomy for RRD and has no effect on the rate of retinal reattachment. J Korean Ophthalmol Soc 2011;52(7):825-831

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