피부 심재성 진균증의 임상조직병리학적 감별진단

고재경 대한의진균학회 1997 대한의진균학회지 Vol.2 No.2

The awareness of classification and differential diagnosis of deep mycoses, particularly systemic infections due to pathogenic fungal infections, is essential for the early detection and appropriate therapy. These systemic pathogenic fungal infections such as histoplasmosis, African histoplasmosis, paracoccidioidomycosis, blastomycosis, are usually endemic in limited areas of continents of America, and Africa. A newly recognized penicilliosis due to Penicillium marneffei, a dimorphic fungus, used to be endemic in Southeast Asia, is now world-wide new threat because the increased numbers of cases have been reported in Australia, France, Italy, the Netherlands, United Kingdom, and the United States. Because of the increased international vistiors to the endemic areas and significant enlargement of the populations existing in immunocompromized state, thus susceptible to systemic mycoses, we, the primary care physicians should be on the alert for the clinicopathologic aspects of the systemic mycoses to make a diagnosis early enough to institute effective therapy.

Epstein-Barr virus(EBV)와 연관된 Nasal type T/Natural Killer(NK)-cell lymphoma 1예

지두현,최지호,성경제,문기찬,고재경 울산대학교 의과대학 1996 울산의대학술지 Vol.5 No.1

Nasal type T/NK-cell lymphoma는 병리조직학적으로 응고성 괴사가 동반된 혈관중심성 침윤을 특징으로하며 T-cell과 NK-cell 항원을 모두 표현하는 면역조직화학염색 소견을 보이는 매우 드문 피부 림프종으로서 EBV와의 연관성이 흔히 보고되고있다. 저자들은 42세 여자에서 발생한, 전신적인 홍반성 구진, 판, 결절의 임상양상을 보였으며 피부 병변에서의 EBV-encoded RNA(EBER)에 대한 in situ hybridization상 양성소견을 보였고 전산화단층촬영, 골주사, 갈륨주사 등의 검사상 비강, 위장관 및 다른 내부장기 침범소견은 보이지 않아서 피부에만 국한된 경우로 사료되는 nasal type T/NK-cell lymphoma 1예를 보고하는 바이다.

Fibroelastolytic Papulosis of the Neck

Koh, Jai Kyoung,Herr, Hwan 대한피부과학회 1999 Annals of Dermatology Vol.11 No.4

Fibroelastolytic papulosis of the neck(FEPN) was introduced by Balus et al in 1997. Before this term was used, white fibrous papulosis of the neck(WFPN) and pseudoaranthoma elasticum-like papillary dermal elastolysis(PDE) had differently been used. These two disease entities had clinical similarities such as asytnptomatic, white to yellow discolored, papular eruptions on the neck in elderly persons. As names implicated, however, they showed variable histological findings, for examples, fibrosis in WFPN or elastolysis in PDE or both in FEPN. Taken into account together, instead of using WFPN or PDE separately, FEPN might be preferred to describe these two kinds of skin diseases. We report a case of a 36-year-old male patient with papules compatible with FEPN, whose biopsy mainly showed elastolysis.

제57차 추계학술대회 및 총회 : 학술대회장 인사

고재경 ( Jai Kyoung Koh ) 대한피부과학회 2005 초록집 Vol.43 No.20

한국에서의 호산구성 농포성 모낭염의 임상 및 병리조직학적 연구

장경애(Kyoung Ae Jang),고광진(Gwang Jin Koh),김성범(Sung Bum Kim),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.10

Background:Eosinophilic pustular folliculitis (EPF) is a rare chronic disease of unknown cause with pruritic papulopustular lesions and a prominent eosinophilic infiltrate. Objective:The purpose of this study was aimed at evaluating the clinical and histopathological features of EPF.Methods:The hospital charts and histopathologic slides of 8 patients with EPF diagnosed at Asan Medical Center from 1989 to 1998 were reviewed. We also reviewed the previously published reports of 10 patients with EPF in Korea. Results:Nine male and nine female patients were enrolled in this study. The mean age at diagnosis of EPF was 26 years in men and 27 years in women. All the patients complained of mild to severe pruritus. EPF was presented with follicular papules or pustules, except 2 patients, who presented with erythematous plaques free of papules or pustules. All the patients showed the typical histopathological findings of EPF. Laboratory investigation showed hypereosinophilia in 73% of patients (11/15). The levels of blood eosinophils tended to decrease as cutaneous lesions resolved. EPF was improved with dapsone in 12 patients and the rest were treated with topical or systemic steroid or antihistamines.Conclusion:EPF may be more common in Korea than can be suspected. Because EPF showed characteristic histopathological findings and EPF responds well to dapsone, the knowledge with this disease may be important to diagnose and treat it. (Korean J Dermatol 2000;38(10):1287~1293)

Micropapular Sarcoidosis 1 예

고재경(Jai Kyoung Koh),문기찬(Kee Chan Moon),최지호(Jee Ho Choi),김경진(Kyoung Jin Kim),배지영(Gee Young Bae),서호석(Ho Seok Suh),성경제(Kyung Jeh Sung) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.5

Cutaneous sarcoidosis occurs in 20-25% of systemic sarcoidosis and be presented without other organ involvement. Most frequent clicical are maculopapule, nodule, plaque, subcutaneous mokule, infiltrative scar and lupus pernio, but uncommon forms including ulcer, alopecia, hypopiminted and micropapular type have been described. Micropapular type is a rare from of cutaneous sarcoidosis with good prognosis. We present a case of generalized micropapular sarcoidosis without other organ involvement

모낭염의 임상 양상을 보인 잠행 백선 1 예

김경진(Kyoung Jin Kim),지민선(Min Sun Jee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.11

Tinea incognito has been used to describe a dermatophyte infection modified by topical or systemic corticosteroid treatment. Lesions are often atypical appearing and the diagnosis is frequently delayed or missed even though by skilled dermatologists. We present here a 70-year-old female patient who had been treated with topical steroid ointment for the erythematous papules on the face and scalp under the diagnosis of contact dermatitis. Initially the lesions were regarded as a folliculitis, but a potassium hydroxide (KOH) preparation showed many fungal hyphae. A fungal culture grew Trichophyton rubrum.

PTBD 관을 통한 담낭암의 피부 착상 전이 1 예

고재경(Jai Kyoung Koh),문기찬(Kee Chan Moon),최지호(Jee Ho Choi),김경진(Kyoung Jin Kim),김은성(Eun Sung Kim),성경제(Kyung Jeh Sung) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.5

The occurrence of metastatic center from the gallbladder to the skin is uncommon and only less than ten cases of distant cutaneous metastases of gallbladder cancer have been reported in literatures. However. cutaneous implantation metastases of gallbladder cancer following laparoscopic cholecystectomy or percutaneous biliary catheter have been described more commonly than distant metastasis. We present herein a case of cutaneous implantation metastasis of gallbladder adenocarcinoma at the sites of percutaneous transhepatic biliary drainage(PTBK).

Short Report / 모낭성 피지선 아포크린 분화를 보인 연골양 한관종 1예

고재경(Jai Kyoung Koh),노기영(Kee Young Roh),양정은(Jeong Eun Yang),김형옥(Hyung Ok Kim),강석진(Suk Jin Kang) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.12

Chondroid syringoma is referred as mixed tumor because it has epithelial structure and mesenchymal elements. Mixed tumors could be divided into two distinct types, eccrine and apocrine. Mixed tumor with follicular, sebaceous and apocrine differentiation is considered as an expression of the common embryologic origin of elements of the folliculosebaceous-apocrine unit. A 32-year old man presented with an asymptomatic firm erythematous nodule on the left cheek. Histologically, it showed typical features of chondroid syringoma with tubules exhibiting branching and cystic dilatation in the myxoid and chondroid stroma. Our case is unique in that the tumor arose from follicular infundibulum with follicular, sebacesous and apocrine differentiation. (Korean J Dermatol 2000;38(12): 1673~1676)

악성 흑생종과 병발한 원발암 2 예

강숙경(Sook Kyoung Kang),장경애(Kyoung Ae Jang),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.7

Survival from malignant melanoma has improved, and as a consequence, the possibility of raised risk of second primary cancers needs to be taken into account in clinical management. We report two cases of second primary cancers in patients with cutaneous malignant melanoma. One is a 61-year-old man suffered from head and neck squamous cell carcinoma with acral lentiginous melanoma, the other is a 65-year-old woman who suffered from malignant lymphoma with superficial spreading melanoma. (Korean J Dermatol 2001;39 (7) 798-802)