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Kwak Kyu‐Won,Aktaruzzaman Md.,Kim Eunsun,Kim Sun Young,Hong Seung‐Beom,Park Ji Yeong,Park Kwanho,Koo Bonwoo,Kim Yong‐Soon 한국곤충학회 2021 Entomological Research Vol.51 No.12
Edible insects are considered novel protein sources, and the edible insect breeding industry is growing rapidly. However, fungal pathogens are a major threat to this industry, and appropriate identification of causative agents is important for the development of antifungal agents. In 2019, strains of the fungal pathogen Metarhizium were isolated from infected second and third instar larvae of the economically important edible insect Protaetia brevitarsis, which were collected from separate farms in Gimhae-si, Gyeongsangnam-do, Korea. Based on morphological characteristics and multilocus phylogenetic analysis of the internal transcribed spacer region, and 50-region of gene encoding the 1-α elongation factor, the fungal strains were identified as Metarhizium majus. Here, we report the detailed phylogenetic characteristics and morphological description of this species, which is prevalent in Korea. Identification of the principal disease-causing agent can help develop disease prevention and antifungal strategies for application in edible insect-rearing farms.
Inhibition of IGF-1-induced sebum production by bilobetin in cultured human sebocytes
( Seung Mee Kim ),( Cong Wang ),( Dong Kyun Hong ),( Kyung Eun Jung ),( Chong Won Choi ),( Young Lee ),( Chang-deok Kim ),( Young-joon Seo ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2
Background: Bilobetin is one of biflavonoids isolated from crude leaf extracts of ginkgo biloba. We previously performed screening test using cultured human sebocytes, and found that bilobetin had a potential for inhibiting lipid production. Sebum production in sebocystes increases under the effects of various stimuli including androgens and insulin-like growth factor-1 (IGF-1). Excessive sebum production often leads to the onset of acne. Objectives: The aim of this study is to demonstrate the effects of bilobetin on IGF-1-induced lipogenesis in sebocytes. Methods: We pretreated SV40T-transformed sebocytes (SV-sebocytes) with bilobetin then stimulated with IGF-1. Effects of bilobetin on lipogenesis of sebocytes were examined by thin layer chromatography (TLC) and Western blot. Results: Bilobetin markedly inhibited IGF-1-induced lipid production in sebocytes, especially in terms of production of squalene and wax ester. Supporting these results, bilobetin showed significant inhibitory effect on squalene synthase promoter activity. In addition, bilobetin significantly down-regulated lipogenic transcription factors such as SREBP-1 and SREBP-2. To delineate the possible action mechanism, we investigated the effect of bilobetin on intracellular signaling. As a result, bilobetin inhibited IGF-1-induced phosphorylation of AKT. Conclusion: Together, these results suggest that bilobetin has an inhibitory potential on sebum production in sebocytes, being applicable for acne treatment.
Preictal versus ictal injection of radiotracer for SPECT study in partial epilepsy: SISCOM
Hong, Seung Bong,Joo, Eun Yeon,Tae, Woo Suk,Cho, Jae-Wook,Lee, Ji-Hyun,Seo, Dae Won,Suh, Yeon-Lim,Hong, Seung Chyul Elsevier 2008 SEIZURE Vol.17 No.4
<P><B>Summary</B></P><P>A 27-year-old man had complex partial seizures and a dysembryoplastic neuroepithelial tumor (DNT) in the left inferior-basal temporal region. The patient's seizures consisted of incomprehensible speech, staring, unresponsiveness, fumbling and then looking around. For the brain SPECT study, radiotracer was injected during the preictal (11s prior to seizure onset), ictal (at 25s out of 47s seizure duration) and interictal periods. Interictal SPECT was subtracted from preictal or ictal-injection SPECTs and then the subtracted SPECTs were overlaid on the patient's MRI (SISCOM). SISCOM with preictal-injection SPECT showed hyperperfusion at the brain lesion, whereas SISCOM with ictal-injection SPECT showed hyperperfusion at the ipsilateral amygdala-hippocampus and hypoperfusion around the tumor lesion. After the DNT and nearby temporal lobe tissues were resected with preservation of amygdala-hippocampus, the patient became seizure free without complaint of subjective postsurgical memory decline. In this patient, SISCOM with preictal injection of radiotracer localized an epileptogenic zone, whereas SISCOM with the ictal injection showed hyperperfusion at the symptomatogenic zone.</P>
Hong, Won-Kee,Park, Seon-Chee,Lee, Ho-Chan,Kim, Jin-Min,Kim, Seung-Il,Lee, Seung-Geun,Yoon, Ki-Joon John Wiley Sons, Ltd. 2010 The structural design of tall and special building Vol.19 No.6
<P>The authors present an experimental and analytical investigation of the modularized hybrid system (MHS) that utilizes the composite structure described in previous studies, that of a wide steel flange and precast concrete. The objective of this paper was to introduce the application of the MHS structural system to a high-rise building in which one additional floor was added while the overall building height was maintained. The 68-m-tall, 18-storey steel building was redesigned to a 19-storey building using the composite beams, which combine the merits of ductile steel and concrete components to withstand external loading while reducing floor height. The bottom flange of the steel beam is reinforced with concrete at a manufacturing plant, eliminating the use of temporary pour forms. The erection process of the composite beams is identical to that of traditional steel construction. This paper also describes more than 30 potential applications of high-rise composite construction using the MHS frames. The advantages of the MHS are presented in terms of reduced structural steel tonnage and shortened construction schedules. Copyright © 2009 John Wiley & Sons, Ltd.</P>
Poster Presentation : Impact of Smoking and Smoking-related Parameters on Coronary Artery Spasm
( Seung Woon Rha ),( Byoung Won Cheon ),( Soon Yong Suh ),( Uk Yeol Chwe ),( Jin Won Kim ),( Chang Gyu Park ),( Hong Seog Seo ),( Dong Joo Oh ),( Young Moo Ro ) 한국지질동맥경화학회 ( 구 한국지질학회 ) 2005 한국지질동맥경화학회 추계학술발표논문집 Vol.1 No.-
MR Imaging in a Child with Scurvy: a Case Report
Seung Woo Choi,Sun-Won Park,Young Se Kwon,오인석,Myung Kwan Lim,Won Hong Kim,Chang Hae Suh 대한영상의학회 2007 Korean Journal of Radiology Vol.8 No.5
Scurvy is very rare disease in industrialized societies. Nevertheless, it still exists in higher risk groups including economically disadvantaged populations with poor nutrition, such as the elderly and chronic alcoholics. The incidence of scurvy in the pediatric population is very low. This study reports a case of scurvy in a 5-year-old girl with cerebral palsy and developmental delay based on MRI findings.
Won-Seok Choi,Seung-Lin Hong 한국무역연구원 2018 貿易 硏究 Vol.14 No.6
The Korean economy has shifted from the manufacturing industry to the service industry since the early 2000s. The purpose of this study is to analyze the causal relationships among trade, foreign direct investment, and economic growth in these transformed industrial structures. We applied the Vector Autoregression (VAR) model to analyze the causality between these variables and to estimate the short-term and long-term effects. As a result, service FDI and service exports were found to have a unidirectional effect on economic growth. In the Impulse Response Function, service exports and service FDI were found to have a significant effect on economic growth and service imports. We also found that service exports and service foreign direct investment have a significant impact on economic growth and service imports, and are also important for both variables in their short-term and long-term effects based on the Impulse Response Function and Forecast Error Variance Decomposition. However, the effect of the two variables gradually decreased over time. Therefore, in order for the Korean economy to grow in a service-oriented economy, it is necessary to develop measures for qualitative growth rather than quantitative expansion of service in exports and FDI.