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Pham Hoang Hien(Pham Hoang Hien ),Tran Thanh Tuan(Tran Thanh Tuan ) People&Global Business Association 2023 Global Business and Finance Review Vol.28 No.3
Purpose: This research investigates the role of employee trust and job satisfaction in the relationship between organizational culture and employee loyalty. Design/methodology/approach: The study was conducted among 355 healthcare professionals working in a private healthcare system in southern cities of Vietnam, including doctors, nurses, and other medical staff. The research method employed was partial least squared structure equation modeling (PLS-SEM) with SmartPLS software for data analysis. Findings: The findings indicate that organizational culture has a direct positive impact on employee loyalty and also affects employee trust and job satisfaction positively. Furthermore, employee trust and job satisfaction act as intermediaries and positively influence employee loyalty toward the organization. Research limitations/implications: The research acknowledges the limitation of the limited sample size and encourages further exploration of these relationships in other contexts. In addition, this study provides valuable insights for the management board of private healthcare organizations in southern cities of Vietnam on how to improve employee loyalty by cultivating a positive organizational culture, promoting employee trust, and enhancing job satisfaction. Originality/value: Overall, this research contributes significantly to the existing literature by examining the interplay between employee trust, organizational culture, job satisfaction, and employee loyalty.
Hien D. Le,Jeng L. Huang,Hien D. Le 사단법인 한국계산역학회 2013 Computers and Concrete, An International Journal Vol.12 No.6
Ready-mixed soil material, known as a kind of controlled low-strength material, is a new way of soil cement combination. It can be used as backfill materials. In this paper, artificial neural network and non-linear regression approach were applied to predict the compressive strength of ready-mixed soil material containing Portland cement, slag, sand, and soil in mixture. The data used for analyzing were obtained from our testing program. In the experiment, we carried out a mix design with three proportions of sand to soil (e.g., 6:4, 5:5, and 4:6). In addition, blast furnace slag partially replaced cement to improve workability, whereas the water-to-binder ratio was fixed. Testing was conducted on samples to estimate its engineering properties as per ASTM such as flowability, strength, and pulse velocity. Based on testing data, the empirical pulse velocity–strength correlation was established by regression method. Next, three topologies of neural network were developed to predict the strength, namely ANN-I, ANN-II, and ANN-III. The first two models are back-propagation feed-forward networks, and the other one is radial basis neural network. The results show that the compressive strength of ready-mixed soil material can be well-predicted from neural networks. Among all currently proposed neural network models, the ANN-I gives the best prediction because it is closest to the actual strength. Moreover, considering combination of pulse velocity and other factors, viz. curing time, and material contents in mixture, the proposed neural networks offer better evaluation than interpolated from pulse velocity only.
PTP Inhibitor XIX Inhibits DUSP22 by Conformational Change
Hien Thi Thu Le,조영창,이세웅,김양균,김권섭,박성구,박병철,조사연 대한화학회 2019 Bulletin of the Korean Chemical Society Vol.40 No.2
Protein tyrosine phosphatases (PTPs) play critical roles in signal transduction by dephosphorylating regulatory proteins involved in many signaling cascades. PTP inhibitors have been reported as potential drugs to treat diseases induced by PTP activity. In this study, we show that PTP inhibitor XIX (PI-19) inhibits dual-specificity phosphatase 22 (DUSP22). Kinetic analysis of PI-19 and DUSP22 suggests that PI-19 inhibits DUSP22 at the catalytic site. In addition, we performed drug affinity responsive targets stability (DARTS) analysis to reveal that the conformation of DUSP22 changed upon binding to PI-19. Moreover, PI-19 blocked DUSP22-mediated dephosphorylation of the signal transducer and activator of transcription 3 (STAT3) at Tyr-705, a critical site for STAT3 activity. Collectively, our results imply that PI-19 is an effective inhibitor of DUSP22 that regulates STAT3 activity.
Synthesis and Characterization of Nitrogen-doped Activated Carbon by Using Melamine
Hien Ngoc Thi Le,정혜경 한국물리학회 2015 새물리 Vol.65 No.1
A simple method to synthesize nitrogen-doped activated carbon by using simple thermal treatment of a mixture of activated carbon and melamine was introduced. About 6 at% of nitrogen were successfully doped into the activated carbon, and it affected the electrochemical properties dramatically. The nitrogen-containing groups could be intercalated and diffused into the pores of the activated carbon and blocked them, resulting in decreased surface area and volume. However, the cyclic voltammetric current density was significantly increased in the nitrogen-doped activated carbon compared to the bare activated carbon, demonstrating the positive effect of nitrogen doping on the performance of supercapacitors and energy storage devices.
Hien Thu Pham,Hyun-Dam Jeong 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.2
Indium-doped zinc oxide nanocrystals (IZO NCs), capped with stearic acid (SA) of different sizes, were synthesized using a hot injection method in a noncoordinating solvent 1-octadecene (ODE). The ligand exchange process was employed to modify the surface of IZO NCs by replacing the longer-chain ligand of stearic acid with the shorter-chain ligand of butylamine (BA). It should be noted that the ligand-exchange percentage was observed to be 75%. The change of particle size, morphology, and crystal structures were obtained using a field emission scanning electron microscope (FE-SEM) and X-ray diffraction pattern results. In our study, the 5 nm and 10 nm IZO NCs capped with stearic acid (SA-IZO) were ligand-exchanged with butylamine (BA), and were then spin-coated on a thermal oxide (SiO2) gate insulator to fabricate a thin film transistor (TFT) device. The films were then annealed at various temperatures: 350 °C, 400 °C, 500 °C, and 600 °C. All samples showed semiconducting behavior and exhibited n-channel TFT. Curing temperature dependent on mobility was observed. Interestingly, mobility decreases with the increasing size of NCs from 5 to 10 nm. Miller-Abrahams hopping formalism was employed to explain the hopping mechanism insight our IZO NC films. By focusing on the effect of size, different curing temperatures, electron coupling, tunneling rate, and inter-NC separation, we found that the decrease in electron mobility for larger NCs was due to smaller electronic coupling.