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대학교 신입생의 특성에 관한 실태조사(1) : 1994학년도 조선대 신입생 일부를 대상으로 1994 Chosun University Entrants
김학렬,조용래,박상학,김상훈,박근무,표경식 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2
The main purposes of this survey are to identify the characteristics of entrants and to provide some suggestions for both a policy planning for entrants and student guidance. For this, entrants(N=868) who were admitted to natural science, engineering, education. fine arts, and other colleges of Chosun University(CU) in 1994 were surveyed with the questionnaire developed by authors. The questionnaire dealt with 1) demographic characteristics. 2) life environment - family relationship, family circumstances, economic conditions, 3) life during high school, 4) attitudes toward both the university and one's subject of study - major sources of informations about the university and attitude toward the university. major sources of informations about one's subject of study and attitude toward one's subject of study, 5) the plan of the university life and course after graduation, 6) interpersonal relationship, and 7) self-perception. The characteristics of entrants were globally examined, and differences between the sexes and differences among colleges in the characteristics described above, if any, were also mentioned. Some suggestions based on the results of this survey were provided in terms of both a policy planning for entrants and student guidance, Finally, one limitation of this survey was discussed from the standpoint of the generalization of the results and some suggestions for future surveys were also discussed.
Park Gyoung Du,Ha Jae Du,Kang Tae In,Kim Jong Su,Kim Yeongho,Lee Sang Jun,Han Im Sik 한국물리학회 2023 Current Applied Physics Vol.50 No.-
The p-n junction electric field (Fpn) of InAs quantum dot solar cell (QDSC) structure was investigated using photoluminescence and photoreflectance spectroscopy. Quantum dot (QD) was fabricated by the Stranski- Krastanov (S–K) and sub-monolayer (SML) methods. From photoreflectance results, the higher Fpn of SML than S–K QDSC from 20 K to 160 K presents that the background carrier concentration of SML QDSC decreases, due to the reduced defect density. Moreover, the SML QDSC shows lower Fpn than S–K QDSC due to the strengthened field screening effect from 160 K to 300 K. This is caused by the improved carrier thermally escaping from the SML QDs and the decreased photo-generated carrier trapping because of the reduced density of defects. The low strain-related defect density improves the efficiency of QDSC. Therefore, the Fpn obtained through the FKO signal from the photoreflectance spectrum could be a reliable method for analyzing the QDSC efficiency.
Park, Seong-Hwan,Kim, Juil,Do, Kee Hun,Park, Jiyeon,Oh, Chang Gyu,Choi, Hye Jin,Song, Bo Gyoung,Lee, Seung Joon,Kim, Yong Sik,Moon, Yuseok American Society for Biochemistry and Molecular Bi 2014 The Journal of biological chemistry Vol.289 No.39
<P>The cell-protective features of the endoplasmic reticulum (ER) stress response are chronically activated in vigorously growing malignant tumor cells, which provide cellular growth advantages over the adverse microenvironment including chemotherapy. As an intervention with ER stress responses in the intestinal cancer cells, preventive exposure to flavone apigenin potentiated superinduction of a regulatory transcription factor, activating transcription factor 3 (ATF3), which is also known to be an integral player coordinating ER stress response-related gene expression. ATF3 superinduction was due to increased turnover of ATF3 transcript via stabilization with HuR protein in the cancer cells under ER stress. Moreover, enhanced ATF3 caused inhibitory action against ER stress-induced cancer chemokines that are potent mediators determining the survival and metastatic potential of epithelial cancer cells. Although enhanced ATF3 was a negative regulator of the well known proinflammatory transcription factor NF-κB, blocking of NF-κB signaling did not affect ER stress-induced chemokine expression. Instead, immediately expressed transcription factor early growth response protein 1 (EGR-1) was positively involved in cancer chemokine induction by ER stressors. ER stress-induced EGR-1 and subsequent chemokine production were repressed by ATF3. Mechanistically, ATF3 directly interacted with and recruited HDAC1 protein, which led to epigenetic suppression of EGR-1 expression and subsequent chemokine production. Conclusively, superinduced ATF3 attenuated ER stress-induced cancer chemokine expression by epigenetically interfering with induction of EGR-1, a transcriptional modulator crucial to cancer chemokine production. Thus, these results suggest a potent therapeutic intervention of ER stress response-related cancer-favoring events by ATF3.</P>
박경민(Gyoung Min Park),민기식(Ki Sik Min),이혜란(Hae Ran Lee),조도준(Do Jun Cho),이대형(Dae Hyoung Lee),심은정(Eun Jung Shim),이소연(So Yeon Lee) 대한소아신경학회 2010 대한소아신경학회지 Vol.18 No.2
Purpose : The purpose of this study was to evaluate childhood seizures to provide appropriate medical services. Methods : We retrospectively reviewed the medical records of 221 chidren under 18 years of age with seizures (excluding febrile convulsion), who were admitted to the pediatric department of Sacred Heart Hospital, Hallym University from 2007 to 2009. Results : The male to female was 1.3:1 and the peak age was 6 years or less, accounting for 63%. The most common causes of seizures according to age were listed as follows; hypocalcemia (41%) and hypoxic ischemic encephalopathies (41%) in the neonatal period, benign convulsion with mild gastroenteritis (BCwMG, 47%) in preschool children (1month and 5 years), and unprovoked seizure (80%) more than 6 years. Electroencephalogram and neuroimaging abnormalities were found in the ratio from 20% and 14% respectively. Conclusion : Seizure is the most common neurologic disease in the childhood. The above results reveal that the causes of childhood seizures in the different age group are different. Therefore, the exact diagnosis of disease according to age is needed. We hope that further clinical studies on this topic will be performed.
박경민(Gyoung Min Park),고정희(Jeung Hee Ko),민기식(Ki Sik Min) 대한소아신경학회 2009 대한소아신경학회지 Vol.17 No.2
저자들은 경련을 일으킨 후 시행한 뇌 자기공명영상에서 광범위한 뇌백질의 변화가 발견된 알렉산더 병 환자를 관찰하여 문헌 고찰과 함께 보고하는 바이다. 이 환자는 로젠탄 섬유의 형성에 관여하는 GFAP 유전자에 돌연변이가 있었고 이것은 알렉산더 병의 진단에 이용되었다. 첫 내원 당시 발달은 정상이었으나 3개월 후 시행한 발달 검사에서 퇴행하는 양상을 보였다. 환아는 항경련제로 경련을 조절하면서 신경운동치료 중으로 경과관찰이 필요하다. Alexander disease(AD) is a rare fatal demyelinating disorder, caused by the mutation of glial fibrillary acidic protein(GFAP) gene. It is characterized by progressive demyelination of central nervous system, and the accumulation of Rosenthal fibers within astrocytes. It is divided into three group: infantile, juvenile, and adult. The infantile type is most common, has onset during the first 2 years of life. It shows macrocephaly and psychomotor delay, spastic paraparesis, seizure, and feeding problems, and usually dies within the first decade. The severity of the pathological changes depend on the age of onset. Radiological study revealed white matter loss, usually with frontal predominance. It is diagnosed by DNA analysis. We present case of a 10-month-old male patient with AD. He had focal seizures, demyelination in the frontal lobe in MRI, and the presence of a K86E mutaion in the GFAP gene, involving the replacement of adenosine with guanine.
복강경적 담낭 절제술 후 부담관에서 발생한 담즙 유출 1예
이상인,박효진,김동주,강진경,정재복,이세준,정준표,이관식,나상규,정미경 대한소화기내시경학회 2000 Clinical Endoscopy Vol.21 No.1
Bile leak is one of the complications of both open and laparoscopic cholecystectomy. The majority of postcholecystectomy leaks occur from the cystic duct stump. Due to their location and small size, accessory ducts are vulnerable to injury during cholecystectomy. A clinical significant leak from the injured accessory bile duct is rare and has rarely been reported in Korea. Endoscopic retrograde cholangiopancreatography (ERCP) has a major role both in detecting such a leak, determining its site, and in managing it. A case was experienced involving a significant bile leak after laparoscopic cholecystectomy from the accessory bile duct in a 49 year-old man. The site of the leak was diagnosed by ERCP and the leak was successfully treated endoscopically by using biliary stenting. However, the diagnosis of the accessory bile duct was established only by a follow-up ERCP done after the healing of the bile leak. This case in herein reported with a review of the related literature.
한국 연안산 패류 중 Vibrio parahaemolyticus의 분포 및 항생제내성 특성 비교
유홍식 ( Hong Sik Yu ),오은경 ( Eun Gyoung Oh ),신순범 ( Soon Bum Shin ),박용수 ( Yong Su Park ),이희정 ( Hee Jung Lee ),김지회 ( Ji Hoe Kim ),송기철 ( Ki Cheol Song ) 한국수산과학회 2014 한국수산과학회지 Vol.47 No.5
The contamination status of Vibrio parahaemolyticus in commercially valuable shellfish from the south and west coasts of Korea and the antimicrobial resistance patterns of isolated V. parahaemolyticus were investigated from July through October, 2011. The range of V. parahaemolyticus concentrations in oysters Crassostrea gigas and short neck clams Venerupis philippinarum was <30~290 MPN/100 g and <30~46,000 MPN/100 g, respectively, and greater than 10,000 MPN/100 g of V. parahaemolyticus was detected from 7 of 40 short neck clams. During the survey period, 436 strains of V. parahaemolyticus were isolated (129 from oysters and 307 from short-neck clams) and the antimicrobial resistance patterns of all of the isolates were examined. Antimicrobial resistance against at least one antibiotic was seen in 79.8% of the oyster isolates (103 strains) and 63.8% of the short neck clam isolates (196 strains). The anti-microbial resistance patterns were relatively simple because the antimicrobial resistance of the isolates was simply due to resistance to ampicillin. Only one oyster isolate and three short neck clam isolates showed multiple antibiotic resistance, i.e., resistance against more than four antibiotics.