Characteristics of the multiphase flow field with super-cavitation induced by successively fired projectiles under-water and cross-medium

Dong-Hui Zhou,Hong-Hui Shi,Hui-Xia Jia 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.1

The multiphase flow field with supercavitation induced by successively fired underwater projectiles is very complicated. It involves the interaction of two or more supercavitating flow fields, which is very different from the supercavitating flow of single underwater projectile. In the paper, the multiphase flow field with supercavitation induced by two successively fired projectiles underwater and cross-media (water-entry and water-exit) was simulated. The interaction effect between supercavities induced by two projectiles was particularly analyzed. The influence mechanism of the supercavity evolution on the motion of two projectiles was also analyzed. The results indicate that, the supercavitating flow fields of two successively fired underwater projectiles interact on each other. The coalescence, separation and collapse of cavities occur during the interaction stage of the supercavitating flow fields, which causes that the second-fired projectile enters the supercavity of the first one. The second-fired projectile can catch up with the first one and then a rear-end collision happens. The collision causes disturbances on the supercavity contour. The impact load of the secondfired projectile during the water-entry period is smaller than that of the first one. The cavities induced by the first- and second-fired projectiles coalesce each other into a cavity, and the second-fired projectile is finally completely wrapped by a supercavity. During the water-entry process, a rear-end collision also happens. In the process of water-exit, the supercavity induced by the first-fired projectile is blocked under the free surface, and then the first-fired projectile flies into the air after throwing off the water layer. Under the influence of the supercavity separated by the first-fired projectile, the second-fired projectile can escape from its own supercavity, and then enter the supercavity of the first-fired projectile. With the supercavity collapse of the first-fired projectile, a new partial cavity generates around the second-fired projectile.

Characteristics of SiC inverter powertrains on common-mode EMI noise

Jia, Xiaoyu,Dong, Bitao,Wang, Hui,Hu, Changsheng,Xu, Dehong The Korean Institute of Power Electronics 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.2

This paper studies the characteristics of SiC inverter powertrains on common-mode (CM) EMI emission. First, a CM noise source model of an EV powertrain is built. Then, the factors of switching frequency, switching speed, and switching ringing on the CM noise source are analyzed. Finally, experiments on a conducted EMI test-bed are carried out to verify the influence of SiC inverters on conducted CM EMI emission in EV powertrains.

Silencing of long noncoding RNA PVT1 inhibits podocyte damage and apoptosis in diabetic nephropathy by upregulating FOXA1

Dong-Wei Liu,Jia-Hui Zhang,Feng-Xun Liu,Xu-Tong Wang,Shao-Kang Pan,Deng-Ke Jiang,Zi-Hao Zhao,Zhang-Suo Liu 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

The number of patients with diabetic nephropathy (DN) is still on the rise worldwide, and this requires the development of new therapeutic strategies. Recent reports have highlighted genetic factors in the treatment of DN. Herein, we aimed to study the roles of long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) and histone 3 lysine 27 trimethylation (H3K27me3) in DN. A model of DN was established by inducing diabetes in mice with streptozotocin. Mouse podocyte clone 5 (MPC5) podocytes and primary podocytes were cultured in normal and high glucose media to observe cell morphology and to quantify PVT1 expression. The roles of PVT1 and enhancer of zeste homolog 2 (EZH2) were validated via loss-of-function and gain-of-function in vitro experiments to identify the interactions among PVT1, EZH2, and forkhead box A1 (FOXA1). The podocyte damage and apoptosis due to PVT1 and FOXA1 were verified with in vivo experiments. PVT1 was highly expressed in MPC5 and primary podocytes in DN patients and in cultures grown in high glucose medium. A large number of CpG (C-phosphate-G) island sites were predicted at the FOXA1 promoter region, where PVT1 recruited EZH2 to promote the recruitment of H3K27me3. The silencing of PVT1 or the overexpression of FOXA1 relieved the damage and inhibited the apoptosis of podocytes in DN, as was evidenced by the upregulated expression of synaptopodin and podocin, higher expression of Bcl-2, and lower expression of Bax and cleaved caspase-3. The key findings of this study collectively indicate that the suppression of lncRNA PVT1 exerts inhibitory effects on podocyte damage and apoptosis via FOXA1 in DN, which is of clinical significance.

Discuss the Ancientry in Modern Headgear of Women

( Hui E Liang ),( Han Jia Chen ),( Dong Sheng Chen ) 한국의류산업학회 2005 Clothing Research Journal Vol.3 No.2

Asp97 is a Crucial Residue Involved in the Ligation of the [Fe4S4] Cluster of IscA from Acidithiobacillus ferrooxidans

( Hui Dan Jiang ),( Xiao Jian Zhang ),( Chen Bing Ai ),( Yuan Dong Liu ),( Jian She Liu ),( Guan Zhou Qiu ),( Jia Zeng ) 한국미생물 · 생명공학회 2008 Journal of microbiology and biotechnology Vol.18 No.6

Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota

Hui-wen Xiao,Yuan Li,Dan Luo,Jia-li Dong,Li-xin Zhou,Shu-yi Zhao,Qi-sheng Zheng,Hai-chao Wang,Ming Cui,Sai-jun Fan 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

Although radiation therapy is a cornerstone of modern management of malignancies, various side effects are inevitably linked to abdominal and pelvic cancer after radiotherapy. Radiation-mediated gastrointestinal (GI) toxicity impairs the life quality of cancer survivors and even shortens their lifespan. Hydrogen has been shown to protect against tissue injuries caused by oxidative stress and excessive inflammation, but its effect on radiation-induced intestinal injury was previously unknown. In the present study, we found that oral gavage with hydrogen-water increased the survival rate and body weight of mice exposed to total abdominal irradiation (TAI); oral gavage with hydrogen-water was also associated with an improvement in GI tract function and the epithelial integrity of the small intestine. Mechanistically, microarray analysis revealed that hydrogen-water administration upregulated miR-1968-5p levels, thus resulting in parallel downregulation of MyD88 expression in the small intestine after TAI exposure. Additionally, high-throughput sequencing showed that hydrogen-water oral gavage resulted in retention of the TAI-shifted intestinal bacterial composition in mice. Collectively, our findings suggested that hydrogen-water might be used as a potential therapeutic to alleviate intestinal injury induced by radiotherapy for abdominal and pelvic cancer in preclinical settings.

Safety evaluation of four entomopathogenic nematode species against two silkworm species

Hui Dong,Yu BI,Jia-Lin WANG,Yan-Qun Liu,Huan Wang 한국곤충학회 2020 Entomological Research Vol.50 No.3

Chinese oak silkworm(Antheraea pernyi) andmulberry silkworm(Bombyx mori) are economically important insects used for silk production and food resource. Entomopathogenic nematodes (EPNs) from the families of Steinernematidae and Heterorhabditidae are beneficial organisms currently considered in biological control. In this paper, we evaluated survival of two silkworm species exposed to four Steinernema species which are widely applied in pest control. The results showed that among four Steinernema species, S. bicornutum and S. feltiae did not have an effect on the larval survival to the two silkworm species, whereas S. carpocapsae and S. glaseri did have an effect. Each Steinernema species poses no threat to hatchability of eggs, pupation rate, larval durations and cocoon shell ratio.

0BTimSim: An Efficient Simulator for Wireless Ad-hoc Networks

Hui Xia,Jia Yu,Guo-Dong Wang,Zhen-Kuan Pan 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.4

With the growth of increasingly complex in wireless ad-hoc networks, performance modeling and evaluation play a crucial part in their design process to ensure successful deployment and exploitation in practice. Compared with the actual implementation (testbeds), simulation has become a valuable tool, which allows studying large scale systems that cannot be built practically. However, most simulators currently used for such networks are intended to evaluate individual routing protocol, which should be extracted from the source code and rewritten in accordance with the simulator’s requirements. Thus, in this paper, we design a new wireless ad-hoc network simulator, called Time Step-based Wireless Ad-hoc Network Simulator (TimSim). It is intended to facilitate the migration of simulation code to real devices via providing useful APIs with real device driver. We use a discrete event processor with time step-based feature as the simulating engine, and the data can be transmitted in bit-level. A unique feature of TimSim is its ability to support the simulation of multi-thread programming. Additionally, we import database access to store the simulation information. Extensive experiments have been conducted to evaluate the efficiency of TimSim. Furthermore, a case study on a real system has been presented to illustrate its practicability.

Antimycobacterial Activity of Fusaric Acid from a Mangrove Endophyte and its Metal Complexes

Jia-Hui Pan,Yi Chen,Yu-Hong Huang,Yi-Wen Tao,Jun Wang,Yan Li,Yi Peng,Tao Dong,Xiao-Min Lai,Yong-Cheng Lin 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.7

Due to the increasing prevalence of multidrug-resistant Mycobacterium tuberculosis, there is an urgent need for new antituberculosis drugs that have novel mechanisms of action. As part of our ongoing search for antimycobacterial metabolites from mangrove endophytes, chemical analysis of the active extract of a strain of Fusarium sp. was performed, which led to the isolation of fusaric acid as the predominant constituent. A variety of metal complexes of fusaric acid were prepared. Antimycobacterial assays showed that Cadmium (II) and Copper (II) complexes exhibited potent inhibitory activity against the M. bovis BCG strain [minimum inhibitory concentration (MIC) = 4 μg/mL] and the M. tuberculosis H37Rv strain (MIC = 10 μg/mL), respectively. This is the first report of the antimycobacterial activity of the mangrove Fusarium metabolite and its coordinating metal complexes.

Application of near-infrared spectroscopy for screening the potato flour content in Chinese steamed bread

Hui Wang,Du Lv,Nan Dong,Sijie Wang,Jia Liu 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.4

Near-infrared (NIR) spectroscopy combinedwith chemometrics was used as a technique to predict thepotato flour content in Chinese steamed bread (CSB). Theinner core of CSB was chosen as the measuring position foracquiring the NIR spectra. Spectra between 4000 and10,000 cm-1 were analysed using a partial least-squaresregression. The coefficient of determination (RCV2 ) and theroot mean square error of cross-validation in the calibrationset were found to be 0.7940–0.8955 and 4.22–5.93,depending on the pre-treatment of the spectra. The externalvalidation set gave an R2 and a ratio to performancedeviation of 0.8865 and 3.07. Reasonable recovery(93.1–102.5%) and good intra-assay (3.3–8.3%) and interassay(7.6–17.2%) precision illustrated the feasibility ofthis method. The result of this study reveals that NIRspectroscopy could be used as rapid tool to determine thepotato flour content in CSB ([20%).