Effect of anion structure of benzenesulfonate-based draw solute in forward osmosis process

DaEun Yang,Yeonsu Cho,Hyo Kang 한국막학회 2022 한국막학회 총회 및 학술발표회 Vol.2022 No.04

Evaluation of Benzenesulfonate-based Draw Solute as Thermoresponsive Draw Solute in Forward Osmosis Process

DaEun Yang,Yeonsu Cho,Hyo Kang 한국막학회 2022 한국막학회 총회 및 학술발표회 Vol.2022 No.11

Dietary schizophyllan reduces mitochondrial damage by activating SIRT3 in mice

Daeun Lee,Ye‑Ram Kim,김재성,Donggyu Kim,Sojin Kim,Sun Young Kim,Kiseok Jang,Jong‑Dae Lee,Chul‑Su Yang 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.4

Schizophyllan (SPG), produced by Schizophyllumcommune, is an exopolysaccharide with multiple academicand commercial uses, including in the food industryand for various medical functions. We previously demonstratedthat SPG conjugated with c-Src peptide exerted asignificant therapeutic effect on mouse models of the acuteinflammatory diseases polymicrobial sepsis and ulcerativecolitis. Here we extended these results by investigatingwhether SPG exerted a protective effect against mitochondrialdamage in the liver via sirtuin 3 (SIRT3) induction,focusing on the deacetylation of succinate dehydrogenase A(SDHA) and superoxide dismutase 2 (SOD2). Liver damagemodels induced by alcohol or conjugated linoleic acid (CLA,which simulates lipodystrophy) in SIRT3−/−,SOD2−/−,andSDHA−/−mice were used. Results showed that dietary supplementationwith SPG induced SIRT3 activation; this wasinvolved in mitochondrial metabolic resuscitation that counteredthe adverse effects of alcoholic liver disease and CLAinduceddamage. The mitochondrial SIRT3 mediated thedeacetylation and activation of SOD2 in the liver and SDHA in adipose tissues, suggesting that SPG supplementationreduced ethanol-induced liver damage and CLA-inducedadverse dietary effects via SIRT3–SOD2 and SIRT3–SDHAsignaling, respectively. Together, these results suggest thatdietary SPG has a previously unrecognized role in SIRT3-mediated mitochondrial metabolic resuscitation duringmitochondria-related diseases.

The Potential Roles of Milk-derived Exosomes for Cutaneous Wound Healing

Daeun KIM,Hyosuk KIM,Sun Hwa KIM,Yoosoo YANG 한국생물공학회 2020 한국생물공학회 학술대회 Vol.2020 No.10

결혼이주여성 대상 문화예술교육 연구 동향 분석

정다은(DaEun Jeong),권소희(SoHee Kwon),이승미(SeungMi Lee),양보은(BoEun Yang),장현진(HyunJin Jang),정진경(JinKyung Jung) 학습자중심교과교육학회 2023 학습자중심교과교육연구 Vol.23 No.20

목적 본 연구는 결혼이주여성 대상 문화예술교육과 관련된 연구 동향을 살펴봄으로써 향후 결혼이주여성 대상 문화예술교육에 대한 방향성 및 시사점을 제시하고자 한다. 방법 본 연구의 분석 대상은 결혼이주여성 대상 문화예술교육 관련 학술지 및 학위논문 총 59편이다. 결혼이주여성 대상 문화예술교육과 관련된 연구 동향을 발표연도, 연구 방법, 연구 분야, 연구 주제, 주제어로 범주화하여 분석하였다. 결과 첫째, 결혼이주여성 대상 문화예술교육과 관련된 연구는 2010년부터 2011년 사이 가장 많이 이루어졌다. 둘째, 연구 방법별 동향은 문헌 연구로 가장 많이 이루어졌고, 질적 연구, 혼합 연구, 양적 연구 순으로 나타났다. 셋째, 연구 분야별 동향은 문학과 관련된 내용이 가장 많았고, 이어서 일반, 미술, 무용, 음악, 연극 순으로 나타났다. 넷째, 연구 주제별 동향은 대영역 중 방향과 관련된 주제에서 교육방안이 가장 높은 비중을 차지하고 있는 것으로 나타났다. 다섯째, 주제어로 알아본 동향은 워드 클라우드의 주제어 크기로 살펴본 결과 다문화가정, 한국문화교육, 한국어 교육, 다문화사회, 문학교육, 문화적응 순으로 나타났고, 정체성 복원, 융합적 문화 정체성, 자아정체성, 서사적 정체성 등 결혼이주여성의 정체성과 관련된 주제어가 포함되어 있음을 알 수 있었다. 결론 본 연구는 다문화 시대에 도래한 한국 사회에 결혼이주여성이 큰 비중을 차지하고 있는 상황 속에서 결혼이주여성 대상 문화예술교육에 관한 연구의 동향을 분석하였으며, 이와 관련된 시사점 및 향후 관련 연구의 방향을 제시한다는 점에서 의의가 있다. Objectives The purposes of this study were to examine the research trends related to culture and arts education for marriage migrant women. Through this study, it intends to provide insights and directions for future culture and arts education targeting marriage migrant women. Methods The subject of this study consists of a total of 59 academic journals and dissertations related to culture and arts education for marriage migrant women. The research trends in cultural arts education targeting marriage migrant women were analyzed and categorized based on publication year, research methodology, research field, research topics, and keywords. Results First, the research related to culture and arts education for marriage migrant women was most prevalent between 2010 and 2011. Second, in terms of research methodology, literature review was the most commonly used method, followed by qualitative research, mixed-methods research, and quantitative research. Third, the re-search fields were predominantly related to literature, followed by general arts, visual arts, dance, music, and theater. Fourth, regarding research topics, the majority focused on educational approaches in the context of broader themes. Lastly, the analysis of keywords through word cloud visualization revealed that topics related to multicultural families, Korean culture education, Korean language education, multicultural society, literary educa-tion, and cultural adaptation were prominent. Additionally, themes associated with the identity of marriage mi-grant women, such as identity restoration, hybrid cultural identity, self-identity, and narrative identity, were also identified. Conclusions This study analyzed the trends in research on culture and arts education targeting marriage migrant women in Korean society, where marriage migrant women hold a significant presence in the multicultural era. The significance lies in providing insights and future directions for related research in the context of marriage migrant women's culture and arts education within the multicultural society of Korea.

미국・일본의 과학기술혁신 행정체계와 시사점

양은진(YANG EUNJIN),홍세호(HONG SE HO),김다은(KIM DAEUN) 한국과학기술기획평가원 2022 이슈페이퍼 Vol.- No.-

묘사분석을 이용한 쌀 과자의 관능적 특성 연구

정다은 ( Daeun Jung ),양정은 ( Jeong Eun Yang ),정라나 ( Lana Chung ) 한국식생활문화학회 2016 韓國食生活文化學會誌 Vol.31 No.1

The objective of this study was to determine sensory profiles of rice confections. The samples used in this study obtained from Korea (traditional Korea rice snack and local specialty rice snack) and three countries (USA, Japan, and China) were evaluated and compared. The sensory characteristics of five kinds of rice confections were evaluated using a sensory test and were analyzed via quantitative description analysis (QDA), principal component analysis (PCA), and hierarchical cluster analysis (HCA). In the descriptive analysis, 10 trained panelists evaluated sensory characteristics consisting of 19 attributes, and there were significant differences (p<0.05) among the 16 characteristics. For the descriptive data, multivariate analysis of variance was carried out and identified differences among the samples. The PCA of rice confections for the first two principal components could explain 85.66% of the variations. The Korean, Japanese, and Chinese rice confections were savory, gritty, and particle-sized, the other Korean local specialty rice confections were fruity, sweet, honey-flavored, compact, and crispy, and those from the USA were glossy, grainy, bright, adhesive, cohesive, crispy, and sweet.

경기도 지역 초등돌봄교실의 급 · 간식 운영 현황

양희순(Yang, Hee Soon),박혜련(Park, Haeryun),송경희(Song, Kyunghee),안윤진(Ahn, Yoonjin),최다은(Choi, Daeun),김군태(Jin, Juntai),이영미(Lee, Youngmi) 한국영양학회 2018 Journal of Nutrition and Health Vol.51 No.3

본 연구는 경기도 소재 초등돌봄교실의 돌봄전담사를 대상으로 집단면담조사 및 설문조사를 실시하여 도시와 농촌의 급 · 간식관리 현황을 비교 분석하였으며, 그 결과를 요약하면 다음과 같다. 첫째, 돌봄전담사 7명을 대상으로 한 집단면담조사 결과, 관련 지침이나 전문가의 도움 없이 돌봄전담사가 급 · 간식 운영을 전담하고 있었으며, 예산 부족으로 인한 질적 저하가 문제점으로 나타났다. 또한 초등돌봄교실의 급 · 간식을 공동관리할 수 있는 전문기관의 필요성이 도출되었다. 둘째, 돌봄전담사 101명을 대상으로 한 설문조사 결과, 학기 중 간식비는 평균 1,463원, 방학 중 급식비는 평균 4,062원이었으며, 학기 중 간식비 (p = 0.015)와 방학 중 급식비 (p = 0.039)는 농촌이 도시보다 유의적으로 적었다. 학기 중, 방학 중 급 · 간식 모두 완제품을 구매해서 제공하는 학교가 가장 많았으며 도시와 농촌 간 차이는 없었다. 셋째, 급식 영양관리기준이 있는 학교는 10% 미만에 불과하였다. 급식식단을 별도로 작성하고 있는 학교는 101개교 중 47개교였으며, 이 중 30개교 (63.8%)는 도시락공급업체로부터 식단을 제공받고 있었고, 17개 (19.3%)에서는 돌봄전담사가 식단을 작성하고 있었다. 간식식단을 작성하는 학교는 80개교로, 이 중 45개교 (44.6%)에서는 돌봄전담사가 식단을 작성하고 있었다. 농촌은 도시에 비해 돌봄전담사가 급식식단을 작성하는 비율이 높은 경향이 있었다 (p = 0.054). 넷째, 위생관리 기준이 있는 학교는 101개교 중 34개교(33.7%)에 불과하였으며, 31개교는 급 · 간식 제공 전 검식을 하지 않고 있었고 정기적인 건강검진을 하지 않는 돌봄전담사도 56.4%에 달했다. 급 · 간식 위생관리 현황은 지역에 따른 차이가 나타나지 않았다. 다섯째, 돌봄전담사가 응답한 적정 1회 간식비는 1,924원으로 실제 간식비보다 높아 적정 간식비에 대한 검토가 필요해 보였다. 바람직한 급 · 간식의 운영형태에 대한 의견에서는 초등돌봄교실 전문 급 · 간식지원센터 설치가 바람직하다는 응답이 48개교로 가장 많았다. 본 연구결과, 초등돌봄교실의 급 · 간식 운영에서는 지역구분과 관계없이 식단관리 및 위생관리 등에서 문제점이 나타났다. 초등돌봄교실에 참여하는 어린이들에게 위생적이며 영양이 풍부한 급 · 간식을 제공하기 위해서는 돌봄전담사가 식단작성 등 관련 업무를 담당하고 있는 현실을 고려하여 현장에서 효율적으로 활용할 수 있는 구체적인 급 · 간식 운영지침 마련이 시급하며, 돌봄전담사를 대상으로 한 영양 · 위생 교육 프로그램 개발이 필요하다. 또한 초등돌봄교실 급 · 간식 권장패턴 및 참고식단 개발이 필요하며, 정부 차원의 효율적인 제도 마련과 지원이 요구된다. 특히 농촌은 도시에 비해 급 · 간식의 단가가 낮고 돌봄전담사가 식단을 작성하는 경우가 많아 급 · 간식 단가의 상승을 우선적으로 고려할 필요가 있으며, 체계적인 급 · 간식 관리를 위한 제도 도입이 선행되어야 할 것이다. Purpose: This study aimed to investigate the current status of food service management in elementary care classes. Methods: A focus group interview with seven care class managers and a survey with 101 care class managers using a self-administered questionnaire in Gyeonggi province were conducted. Results: In the focus group interview, purchased meals and snacks were evaluated as low quality by the care class managers. Frequent use of frozen or processed food and products with low prices were also reported as problems. Care class managers were in charge of meal and snack planning without any guidelines or expert advices. The results of the survey show that most schools serve purchased snacks and meals. The average unit costs of one meal and snack were 4,062 and 1,463 Won, respectively. The average unit costs of snacks during semester (p = 0.015) and vacation (p = 0.039) were significantly lower in rural than urban areas. The percentages of schools that prepared nutrition standards for meal and snack planning in elementary care classes were only 7.4% and 10.9%, respectively. The meal menus were mostly provided by catering service companies, and the snack menus were planned mostly by the care class managers. Menu planning by the care class managers was more usual in rural than urban areas (p = 0.054 for meal planning and p = 0.008 for snack planning). Just 33.7% of schools introduced safety standards for food service in elementary care classes, and more than half of the respondents (56.4%) did not do a regular medical check-up. Only 33.7% of the respondents received education for food safety. Conclusion: These results show the necessity for establishment of detailed guidelines for food service in elementary care classes and for the introduction of a food safety and nutrition education program customized for care class managers.

Alterations in the Transcriptional Programs of Myeloma Cells and the Microenvironment during Extramedullary Progression Affect Proliferation and Immune Evasion

Ryu, Daeun,Kim, Seok Jin,Hong, Yourae,Jo, Areum,Kim, Nayoung,Kim, Hee-Jin,Lee, Hae-Ock,Kim, Kihyun,Park, Woong-Yang American Association for Cancer Research 2020 Clinical Cancer Research Vol.26 No.4

<P><B>Purpose:</B></P><P>In multiple myeloma, extramedullary progression is associated with treatment resistance and a high mortality rate. To understand the molecular mechanisms controlling the devastating progression of myeloma, we applied single-cell RNA-sequencing (RNA-seq) to myeloma in the bone marrow and myelomatous pleural effusions or ascites.</P><P><B>Experimental Design:</B></P><P>Bone marrow or extramedullary myeloma samples were collected from 15 patients and subjected to single-cell RNA-seq. The single-cell transcriptome data of malignant plasma cells and the surrounding immune microenvironment were analyzed.</P><P><B>Results:</B></P><P>Comparisons of single-cell transcriptomes revealed the systematic activation of proliferation, antigen presentation, proteasomes, glycolysis, and oxidative phosphorylation pathways in extramedullary myeloma cells. The myeloma cells expressed multiple combinations of growth factors and receptors, suggesting autonomous and pleiotropic growth potential at the single-cell level. Comparisons of the tumor microenvironment revealed the presence of cytotoxic T lymphocytes and natural killer (NK) cells in both the bone marrow and extramedullary ascites, demonstrating a gene-expression phenotype indicative of functional compromise. In parallel, isolated myeloma cells persistently expressed class I MHC molecules and upregulated inhibitory molecules for cytotoxic T and NK cells.</P><P><B>Conclusions:</B></P><P>These data suggest that myeloma cells are equipped with specialized immune evasion mechanisms in cytotoxic microenvironments. Taken together, single-cell transcriptome analysis revealed transcriptional programs associated with aggressive myeloma progression that support autonomous cell proliferation and immune evasion.</P>

A Case of Idiopathic Infratentorial Superficial Siderosis

Shin, Daeun,Yang, Seok-Yul,Kim, Youngwook,Ryu, Ho-Sung,Lee, Hoseok Korean Society of Magnetic Resonance in Medicine 2020 Investigative Magnetic Resonance Imaging Vol.24 No.1

Superficial siderosis is attributed to hemosiderin deposition in the subpial layers of the nervous system. The clinical features of infratentorial superficial siderosis (ISS) are hearing loss, cerebellar ataxia, and corticospinal tract signs and the most common cause of idiopathic ISS is a dural defect. As magnetic resonance imaging (MRI) has advanced, the diagnosis of infratentorial superficial siderosis can be confirmed by unique radiological findings in MRI. Here, we report on a female patient diagnosed with idiopathic ISS by means of clinical symptoms and radiological findings.