Clinical Manifestations and Surgical Treatment Outcomes of Paranasal Sinus Osteoma

Cho Ara,Jung Youngrak,Park Ju Ha,Jeong Yeonsu,Cho Hyung-Ju 대한비과학회 2022 Journal of rhinology Vol.29 No.1

Background and Objectives: Osteomas are the most common benign tumors of the nasal cavity and paranasal sinuses (PNSs). In this study, clinical features and imaging findings were analyzed in patients with osteoma confirmed by ostiomeatal unit (OMU) computed tomography (CT) and PNS CT, and the surgical treatment performed at our hospital was introduced.Methods: The Severance Clinical Research Analysis Portal (SCRAP) service of Severance Hospital was used to collect research data. A total of 128 cases of osteomas of the nasal cavity or PNSs confirmed by OMU CT or PNS CT was retrospectively reviewed, including the location and size of the osteoma, clinical features, accompanying findings on imaging tests, and cases of surgical treatment.Results: In this study, osteomas were found in about 0.55% of patients who underwent computed tomography. Osteomas were most frequently found in the ethmoid sinus, followed by the frontal sinus, fronto-ethmoid sinus, maxillary sinus, intranasal sphenoid sinus, and maxillary sinus-ethmoid sinus. Patients with osteomas complained of symptoms such as rhinorrhea, postnasal drip, nasal congestion, hyposmia, headache, visual disturbance, and lacrimal duct obstruction.Conclusion: Surgical treatment was considered for patients presenting with severe headache, visual field symptoms, or accompanying rhinosinusitis. Surgery was performed by endoscopic or external approaches depending on location and size of the osteoma.

Synthesis of dual-responsive imidazolium-based ionic liquid and its application to draw solutes of forward osmosis

Yeonsu Cho,Hyo Kang 한국막학회 2023 한국막학회 총회 및 학술발표회 Vol.2023 No.05

2021년 하계 동중국해의 해양수질환경 및 해저퇴적물환경

조성민(Seongmin Cho ),김연수(Yeonsu Kim),정민기(Mingi Jeong),조현서(Hyeonseo Cho) 한국해양환경·에너지학회 2021 한국해양환경·에너지학회 학술대회논문집 Vol.2021 No.10

본 연구 대상지역인 동중국해 해역은 한국과 일본, 중국이 서로 인접하고 있으며, 대만난류, 중국에서 흘러나온 연안수와 황해 저층냉수 등의 다양한 수괴들이 서로 상접하며, 다양한 환경특성을 나타내고있다(Zhang and Weng et al., 1996). 특히, 하계에는 양자강으로부터 흘러 나오는 담수의 영향을 크게 받는 지역이며, 먹이생물이 풍부하며, 기초생물생산성이 높아서 어장의 가치가 매우 높은 곳으로 알려져 있다(Guo and Zhang et al., 1996). 이러한 특징적인 환경이 수질환경 및 퇴적환경에 미치는 영향을 해양수질환경 및 해저퇴적물 환경으로 파악하여 기초자료로 제공하고자 한다. 분석항목에는 수온, 염분, DO, COD 등 13개의 항목에 대해 ‘해양환경공정시험기준(해양수산부, 2020)’에 준하여 분석을 실시하였다. 표층에서 수온은 21.89 ~ 25.43 ℃, 염분은 24.13 ~ 32.33 psu, 수소이온농도는 8.22 ~ 8.47, 부유물질은 2.43 ~ 7.29 mg/L, COD의 경우에는 1.04 ~ 2.36 mg/L, Chl-a는 1.83 ~ 6.48 μg/L, 용존 무기질소는 평균 1.17 ~ 3.11 uM, 인산은 평균 0.02 ~ 0.11 uM, 규산 규소는 3.52 ~ 10.69 uM, 총 질소는 0.226 ~ 0.323 mg/L, 총 인은 0.006 ~ 0.024 mg/L 의 범위를 나타내었다. 퇴적물 COD의 경우 일본 수산용수기준치인 20mg/g-dry(일본수산자원보호협회편, 2000)보다 낮은 값을 나타내었다. 또한 주성분 분석을 실시하여 해역의 특성을 파악하였다. In the East China Sea, the subject area of this study, Korea, Japan, and China are adjacent to each other, and various water masses such as the Taiwan warm current, coastal water flowing from China and cold water from the Yellow Sea are in contact with each other, showing various environmental characteristics(Zhang and Weng et al., 1996). In particular, it is an area that is greatly affected by freshwater flowing from the Yangtze River in the summer, and it is known as a place of high valuable fishery because of its abundant food organisms and high productivity of basic organisms (Guo and Zhang et al., 1996). The effect of these characteristic environments on the seawater quality environment and sedimentation environment is to be provided as basic data by understanding the seawater quality environment and the marine sediment environment. Thirteen items such as water temperature, salinity, dissolved oxygen (DO), chemical oxygen demand (COD) were analyzed according to the Marine Environment Processing Test Standard (The Ministry of Maritime Affairs and Fisheries, 2020). The concentrations of the surface water temperature ranged from 21.89 to 25.43 ℃, the Salinity ranged from 24.13 to 32.33 psu, pH ranged from 8.22 to 8.47, Suspended Particulate Matter(SPM) ranged from 2.43 to 7.29 mg/L, COD ranged from 1.04 to 2.36 mg/L, Chl-a ranged from 1.83 to 6.48 μg/L, DIN ranged from 1.17 to 3.11 uM, DIP ranged from 0.02 to 0.11 uM, DSi ranged from 3.52 to 10.69 uM, TN ranged from 0.226 to 0.323 mg/L, TP ranged from 0.006 to0.024 mg/L. Sediment showed lower concentration of COD than 20 mg/g-dry each which are the fisheries environment standard in Japan(Association of marine resource preservation of Japan, 2000). Principal component analysis was performed to characterize the seawater quality.

Heat wave predicting over South Korea with teleconnection drivers based on machine learning

Yeonsu Lee,Cheolhee Yoo,Dongjin Cho,Jungho Im 한국기상학회 2019 한국기상학회 학술대회 논문집 Vol.2019 No.4

Comparative characterization of the fecal microbiome in domestic and wild animals

Yeonsu OH,Sung-Hyun MOON,Ho-Seong CHO 한국생물공학회 2018 한국생물공학회 학술대회 Vol.2018 No.10

Mycobacterium genavense induced mycobacteriosis in an Indian peafowl (Pavo cristatus)

( Yeonsu Oh ),( Sang-joon Lee ),( Dong-seob Tark ),( Ho-seong Cho ) 한국동물위생학회(구 한국가축위생학회) 2021 韓國家畜衛生學會誌 Vol.44 No.2

The report describes an avian mycobacteriosis in a captive wild bird. A 7-year-old female Indian peafowl (Pavo cristatus) maintained in a zoo of Korea presented a gradual cachexia and eventually was found dead. At necropsy, severely atrophied pectoral muscles exposing the keel bone were noticed. Yellowish thick nodules in varying sizes were scattered in all lobes of lungs, liver and spleen, suggesting mycobacteriosis. Histopathologically, multifocal to coalescing granulomas surrounded by multinucleated giant cells were observed. Numbers of acid-fast bacilli were revealed in granulomas. Then, a series of molecular diagnostic techniques were followed: a nested PCR, DNA sequencing and bioinformatics analysis. It resulted as Mycobacterium genavense. The identification of M. genavense as an etiological agent suggested that it might serve as a risk factor for other captive wild animals, and for a potential zoonotic risk since M. genavense have been a definite cause of disseminated mycobacterial infection in immunocompromised people. To the authors’ knowledge, this is the first report of avian mycobacteriosis with M. genavense in a captive Indian peafowl.

Two Dimensional Molybdenum Diselenide Field Effect Transistor with Polymer-Brush/Channel Interface for Touch Sensor Applications

Yeonsu Jeong,Ji Hoon Park,Hyunmin Cho,Seongil Im 한국진공학회 2020 한국진공학회 학술발표회초록집 Vol.2020 No.2

Development of sandwich enzyme-linked immunosorbent assay for a large-scale detection of porcine transmissible gastroenteritis virus in feces

( Yeonsu Oh ),( Sang-joon Lee ),( Ho-seong Cho ),( Dongseob Tark ) 한국동물위생학회(구 한국가축위생학회) 2020 韓國家畜衛生學會誌 Vol.43 No.4

Porcine transmissible gastroenteritis (TGE) has been a significant cause of economic losses in pig farming industry since 1950s. Although transmissible gastroenteritis virus (TGEV) has declined in recent years, it should not be excluded because of its characteristics; the frequency of gene mutation, the mortality in piglets, and the possibility for sudden incidence. Therefore, the herd-level monitoring of the virus is important to prevent further circulation of TGE. The aim of this study is to develop a large-scale sandwich enzyme-linked immunosorbent assay (ELISA) with high specificity to rapidly detect TGEV in feces by using monoclonal antibodies (Mabs). The TGEV specific Mabs were produced in hybridoma cells. Among the Mabs belonged to the IgG class developed by this study, the final selected 8H6, 1B7, 4G3, and 1F8 were identified to have the neutralization ability against TGEV. The sandwich ELISA was established using 8H6 as a reporter antibody and 1B7 and the reported 5C8 as a capture antibody. The developed sandwich ELISA was able to distinguish TGEV from other pathogenic diarrheal agents (porcine rotavirus, porcine reovirus, porcine epidemic diarrhea virus (PEDV), E. coli, and C. perfringens) in tissue culture as well as fecal samples. And the detection rate of TGEV in feces was 80% compared with RT-PCR. The results suggested that the developed sandwich ELISA may be useful in the herd-level monitoring for effective preventive measures due to the early diagnosis of TGEV using a large amount of samples.

Decadal analysis of livestock tuberculosis in Korea (2013∼2022): Epidemiological patterns and trends

( Yeonsu Oh ),( Dongseob Tark ),( Gwang-seon Ryoo ),( Dae-sung Yoo ),( Woo H. Kim ),( Won-il Kim ),( Choi-kyu Park ),( Won-keun Kim ),( Ho-seong Cho ) 한국동물위생학회 2023 韓國家畜衛生學會誌 Vol.46 No.4

This study provides a comprehensive analysis of the epidemiological trends and challenges in managing tuberculosis (TB) in livestock in Korea from 2013 to 2022. Tuberculosis, caused by the Mycobacterium tuberculosis complex, is a significant zoonotic disease affecting cattle, deer, and other domesticated animals. Despite the initiation of a test-and-slaughter eradication policy in 1964, TB has continued to persist in Korean livestock, particularly in cattle and deer. This study used data from the Korea Animal Health Integrated System and provincial animal health laboratories to analyze TB incidence in various livestock including different cattle breeds and deer species. The results from 2013 to 2022 showed a peak in TB cases in 2019 with a subsequent decline by 2022. The study highlighted a significant incidence of TB in Korean native cattle and the need for amore inclusive approach towards TB testing and control in different cattle breeds. Additionally, the study underscored the importance of addressing TB in other animals such as goats, wildlife, and companion animals for a holistic approach to TB eradication in Korea. The findings suggest that while the test-and-slaughter strategy has been historically effective, there is a need for adaptation to the current challenges, and learning from successful eradiation stories on other countries like Australia. A collaborative effort involving an expanded surveillance system, active private sector participation, and robust government support essential for the efficient eradication of TB in livestock in Korea.

Sustained SARS-CoV-2 antibody response in domestic pets: Insights from a longitudinal study

( Yeonsu Oh ),( Dongseob Tark ),( Choi-kyu Park ),( Ho-seong Cho ) 한국동물위생학회 2023 韓國家畜衛生學會誌 Vol.46 No.4

The COVID-19 pandemic, triggered by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has not only impacted human health on a global scale but also raised concerns about the vulnerability of a wide array of animals that are in close contact with humans. Particularly, the potential for infection and the subsequent immune response in domestic pets such as dogs and cats remain largely unexplored under natural living conditions. In this study, we have undertaken the task of detecting and tracking the presence of antibodies against SARS-CoV-2 in a small cohort of household pets-specifically, two dogs and two cats. Employing techniques such as the indirect ELISA and plaque reduction neutralization tests, we observed that the neutralizing antibodies against SARS-CoV-2 in these animals were maintained for a duration of up to six months following their initial positive test result. This duration mirrors the antibody response documented in human cases of COVID-19, suggesting a comparable post-infection immune response timeline between humans and these domestic animals.