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      • KCI등재

        Taxonomic study of the subtribe Pemphredonina Dahlbom, 1835 (Hymenoptera: Crabronidae) with a new species and six new records from China

        Bashir Nawaz Haider,Yue Dan,Jiang Huifen,Ma Li,Li Qiang 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.4

        In this revision of the subtribe Pemphredonina (Crabronidae: Pemphredoninae: Pemphredonini) from China, we reported several species present in respected subtribe, out of which one species is new to science Passaloecus frontirugatus Bashir and Ma, sp. nov., and six species are recorded for the first time from China, including Polemistus palawanensis Tsuneki, Diodontus insidiosus Spooner, Diodontus handlirschi Kohl, Diodontus tiemudzhin Tsuneki, Diodontus spinicerus Kazenas, and Diodontus kuroo Tsuneki. A key to genera and the species of Diodontus and Passaloecus from China is also provided. Distributional records from China of each genus are also g

      • Isolation and Structure Elucidation, Molecular Docking Studies of Screlotiumol from Soil Borne Fungi Screlotium rolfsii and their Reversal of Multidrug Resistance in Mouse Lymphoma Cells

        Ahmad, Bashir,Rizwan, Muhammad,Rauf, Abdur,Raza, Muslim,Azam, Sadiq,Bashir, Shumaila,Molnar, Joseph,Csonka, Akos,Szabo, Diana Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4

        A new compound namely (13-(3,3-dihydroxypropyl)-1,6-dihydroxy-3,4-dihydro-1H-isochromen-8(5H)-one (1) was isolated from an ethyl acetate extract of the borne fungi Screlotium rolfsii. Its chemical structure was elucidated by spectroscopic analysis. Screlotiumol 1 were evaluated for their effects on the reversion of multidrug resistant (MDR) mediated by P-glycoprotein (P-gp) of the soil borne fungi. The multidrug resistant P-glycoprotein is a target for chemotherapeutic drugs in cancer cells. In the present study rhodamine-123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma which showed excellent MDR reversing effect in a dose dependent manner against mouse T-lymphoma cell line. Moreover, molecular docking studies of compound-1 also showed better results as compared with the standard. Therefore the preliminary results obtained from this study suggest that screlotiumol 1 could be used as a potential agent for the treatment of cancer.

      • Comparative Study of Carcinoembryonic Antigen Tumor Marker in Stomach and Colon Cancer Patients in Khyber Pakhtunkhwa

        Ahmad, Bashir,Gul, Bushra,Ali, Sajid,Bashir, Shumaila,Mahmood, Nourin,Ahmad, Jamshed,Nawaz, Seema Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

        Background: Due to the increase in morbidity and mortality rate, cancer has become an alarming threat to the human population worldwide. Since cancer is a progressive disorder, timely diagnosis would be helpful to prevent/stop cancer from progressing to severe stage. In Khyber Pakhtunkhwa, Pakistan, most of the time, tumors are diagnosed with endoscopy and biopsy; therefore rare studies exist regarding the diagnosis of gastrointestinal (GIT) carcinomas based on tumor markers, especially CEA. Objectives: This study made a comparative analysis of CEA in admitted hospitalized stomach and colon cancer patients diagnosed as GIT with biopsy. Materials and Methods: In this study, a total of 66 cases were included. The level of CEA was determined in the blood of these patients using ELISA technique. Results: Out of 66 patients, the level of CEA was high in 59.1% of the total, 60.7% in colon cancer patients and 57.9 % in stomach cancer patients. Moreover, the incidence of colorectal and stomach cancer was greater in males as compared to females. Patients were more of the age group of 40-60 and the level of CEA was comparatively higher in patients (51.5%) with histology which was moderately differentiated, than patients with well differentiated and poorly differentiated tumor histology. Conclusions: CEA level was high in more than 50% of the total patients. Moreover, CEA exhibited higher sensitivity for colon than stomach cancer.

      • KCI등재

        Dynamic Wetting in Microfluidic Droplet Formation

        Shazia Bashir,Xavier Casadevall i Solvas,Muhammad Bashir,Julia Margaret Rees,William Bauer Jay Zimmerman 한국바이오칩학회 2014 BioChip Journal Vol.8 No.2

        The extent to which the carrier fluid wets the walls of a microchannel is crucial in the droplet formation process for segmented flow microfluidic applications and can be influenced by the use of surfactants. Surfactants dynamically modify the microchannel surface leading to stabilization of the two phase interface, affecting the droplet formation process. An experimental study of the influence of hydrophobic surfactant (Span 80) during the formation of water-inoil droplets in a T-shaped microchannel geometry is presented and the wetting properties of the microchannel walls were characterized. The range of data to be analyzed on the microscale is estimated from the macroscopic interfacial tension and contact angle measurements. The critical micelle concentration (CMC) level at the microscale was estimated by observing the trend of droplet length variation with concentration of surfactant in a microchannel. Microchannels used in this work were fabricated using softlithography methods and bonded using a custom-made plasma bonding setup that does not require an ultra high vacuum chamber and hence saves the fabrication cost.

      • Level and Evaluation of Tumor Marker CA-125 in Ovarian Cancer Patients in Khyber Pakhtunkhwa, Pakistan

        Ahmad, Bashir,Nawaz, Seema,Ali, Sajid,Bashir, Shumaila,Mahmood, Nourin,Gul, Bushra Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

        Background: Due to the increase in morbidity and mortality rate, cancer has become an alarming threat to the human population worldwide. Since cancer is a progressive disorder, timely diagnosis is necessary to prevent/stop cancer from progressing to a severe stage. In Khyber Paktunkhwa, Pakistan, many tumors are diagnosed with endoscopy and biopsy; rare studies exist regarding the diagnosis and evaluation of ovarian cancer, based on tumor markers like CA-125. Objectives: The objectives of this study were to investigate and evaluate levels of CA-125 in hospitalized ovarian cancer patients. Materials and Methods: In this study, a total of 63 admitted patients having ovarian cancer by biopsy were included. The level of CA-125 was determined in the blood of these patients using ELISA technique. Results: Out of 63 patients, the level of CA-125 was high in 52%. The affected individuals were more in the group of 40-60 and the level of CA-125 was comparatively higher in patients having moderately differentiated histology than those having well differentiated and poorly differentiated tumor histology. Moreover, the highest level of CA-125 was present among the patients having serous subtype of carcinoma and the common stage of carcinoma was stage II followed by stage III, I and IV. Conclusions: CA-125 level was high in more than 50% of the total patients. Moreover, CA-125 elevation was more common in serous subtype and stage II cancer patients.

      • KCI등재

        Prediction of ultimate moment anchorage capacity of concrete filled steel box footing

        Muhammad Aun Bashir,Hitoshi Furuuchi,Tamon Ueda,M. Nauman Bashir 국제구조공학회 2013 Steel and Composite Structures, An International J Vol.15 No.6

        The objective of the study is to predict the moment anchorage capacity of the concrete filled steel box (CFSB) as footing by using the 3D finite element program CAMUI developed by authors' laboratory. The steel box is filled with concrete and concrete filled steel tube (CFT) column is inserted in the box. Numerical simulation of the experimental specimens was carried out after introducing the new constitutive model for post peak behavior of concrete in compression under confinement. The experimental program was conducted to verify the reliability of the simulation results by the FE program. The simulated peak loads agree reasonably with the experimental ones and was controlled by concrete crushing near the column. After confirming the reliability of the FEM simulation, effects of different parameters on the moment anchorage capacity of concrete filled steel box footing were clarified by conducting numerically parametric study.

      • KCI등재

        A Study of the Thermal Properties of Nano-crystalline Binary Oxides Prepared by Co-precipitation Method

        Tahira Amer Bashir Ziya,Muhammad Naeem Ashiq,고재현,Farooq Bashir,Ghulam Shabbir 한국물리학회 2020 New Physics: Sae Mulli Vol.70 No.2

        The Thermal properties of nano-crystalline CeO2, FeO, MgO, Ho2O3, NiO and Y2O3, prepared by using the co-precipitation method, have been investigated using X-ray diffraction (XRD) at room temperature. The integrated intensity data obtained from the X-ray diffraction experiments was utilized to determine the temperature factor (B(T)), mean square amplitude of vibration (u2(T)), Debye temperature (D), melting point (Tm) and activation energy for vacancy formation (Ef ). The values of (B(T)) and (u2(T)) in the present case were found to be large while the values of D and Ef were found to be lower than the corresponding values reported for the binary oxides with large particle sizes. This suggests that a decrease in particle size from micro to nano-scale may induce weakening of the bonds. On a nano-scale as compared to ordinary size, the values of the melting points were found be higher for the heavier atomic oxides.

      • The inhibition action of analgin on the corrosion of mild steel in acidic medium: A combined theoretical and experimental approach

        Bashir, Sumayah,Sharma, Vivek,Lgaz, Hassane,Chung, Ill-Min,Singh, Ambrish,Kumar, Ashish Elsevier 2018 Journal of molecular liquids Vol.263 No.-

        <P><B>Abstract</B></P> <P>The corrosion inhibitive property of analgin on mild steel in 1 M HCl was determined for the first time by using experimental and theoretical studies. Weight loss results showed that analgin showed 96.1% inhibition efficiency at 4000 ppm and 298 K. Results showed that analgin acts as a mixed type inhibitor. Effect of concentration of inhibitor and temperature on corrosion inhibition efficiency has been studied. Effect of kinetic and thermodynamic parameters has also been reported. Results show that adsorption of analgin on metal surface follows Langmuir adsorption isotherm. A detailed theoretical data was obtained from Molecular dynamic simulations and quantum chemical calculations using density functional theory (DFT). All the combined results showed appreciable inhibition efficiencies. The morphological and topographical studies were done by SEM and AFM techniques. All the results were in good agreement with each other.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Corrosion protection properties of analgin have been investigated. </LI> <LI> Potentiodynamic polarization curves reveal that tested inhibitor act as mixed type. </LI> <LI> The adsorption of inhibitor obeys Langmuir adsorption isotherm. </LI> <LI> Surface morphology was examined by SEM and AFM. </LI> <LI> The experimental results were correlated with quantum chemical and molecular dynamic stimulation results. </LI> </UL> </P>

      • SCISCIESCOPUS

        Methodology to determine the impact of linewidth variation on chip scale copper/low-<i>k</i> backend dielectric breakdown

        Bashir, Muhammad,Milor, Linda,Kim, Dae Hyun,Lim, Sung Kyu Elsevier 2010 Microelectronics and reliability Vol.50 No.9

        <P><B>Abstract</B></P><P>Low<I>-k</I> time-dependent dielectric breakdown (TDDB) has been found to be a function of metal linewidth, when the distance between the lines is constant. Modeling requires determining the relationship between TDDB and layout geometries. To determine this relationship, comb test structures have been design and implemented in 45nm technology. In this work, low<I>-k</I> dielectric breakdown, low<I>-k</I> dielectric vulnerable areas, and linewidth variation are linked to full chip lifetimes.</P>

      • Natural Food Additives and Preservatives for Fish-Paste Products: A Review of the Past, Present, and Future States of Research

        Bashir, Khawaja Muhammad Imran,Kim, Jin-Soo,An, Jeong Hyeon,Sohn, Jae Hak,Choi, Jae-Suk Hindawi Limited 2017 Journal of food quality Vol.2017 No.-

        <P>Fish-paste products, also known as fish cakes or surimi-based products, are worldwide favorites. Surimi, a wet protein concentrate of fish muscle, is used as an intermediate raw material to produce surimi seafood. The flavor, texture, taste, shelf-life, and market value of surimi-based products depend on the source of the fish meat, type of applied heat treatment, and additives used to prepare the surimi. While preparing surimi with chemical additives, several problems have been observed, such as a lack of unique characteristics, inferior acceptability, and poor functionality. Various types of fish-paste products have been developed by using different ingredients (e.g., vegetables, seafood, herbs and oriental medicines, grains and roots including carrots, and functional food materials). However, a systematic review of fish-paste products prepared using natural food additives has not yet been performed. Therefore, the quality characteristics of fish-paste products and their functionalities were elucidated in this study. With the increasing demand for surimi seafood products, the functional properties, physiochemical properties, and shelf-life of surimi-based products need to be improved. This review will aid the preparation of new value-added products in the surimi industry.</P>

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