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        “V-junction”: a novel structure for high-speed generation of bespoke droplet flows

        Ding, Yun,Casadevall i Solvas, Xavier,deMello, Andrew The Royal Society of Chemistry 2015 The Analyst Vol.140 No.2

        <P>We present the use of microfluidic “V-junctions” as a droplet generation strategy that incorporates enhanced performance characteristics when compared to more traditional “T-junction” formats. This includes the ability to generate target-sized droplets from the very first one, efficient switching between multiple input samples, the production of a wide range of droplet sizes (and size gradients) and the facile generation of droplets with residence time gradients. Additionally, the use of V-junction droplet generators enables the suspension and subsequent resumption of droplet flows at times defined by the user. The high degree of operational flexibility allows a wide range of droplet sizes, payloads, spacings and generation frequencies to be obtained, which in turn provides for an enhanced design space for droplet-based experimentation. We show that the V-junction retains the simplicity of operation associated with T-junction formats, whilst offering functionalities normally associated with droplet-on-demand technologies.</P> <P>Graphic Abstract</P><P>We present the use of microfluidic “V-junctions” as a droplet generation strategy that incorporates enhanced performance characteristics when compared to more traditional “T-junction” formats. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4an01730g'> </P>

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        Dynamic Wetting in Microfluidic Droplet Formation

        Shazia Bashir,Xavier Casadevall i Solvas,Muhammad Bashir,Julia Margaret Rees,William Bauer Jay Zimmerman 한국바이오칩학회 2014 BioChip Journal Vol.8 No.2

        The extent to which the carrier fluid wets the walls of a microchannel is crucial in the droplet formation process for segmented flow microfluidic applications and can be influenced by the use of surfactants. Surfactants dynamically modify the microchannel surface leading to stabilization of the two phase interface, affecting the droplet formation process. An experimental study of the influence of hydrophobic surfactant (Span 80) during the formation of water-inoil droplets in a T-shaped microchannel geometry is presented and the wetting properties of the microchannel walls were characterized. The range of data to be analyzed on the microscale is estimated from the macroscopic interfacial tension and contact angle measurements. The critical micelle concentration (CMC) level at the microscale was estimated by observing the trend of droplet length variation with concentration of surfactant in a microchannel. Microchannels used in this work were fabricated using softlithography methods and bonded using a custom-made plasma bonding setup that does not require an ultra high vacuum chamber and hence saves the fabrication cost.

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