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비위(脾胃)와 간(肝)과의 상관성(相關性)에 관한 문헌고찰(文獻考察)
공경환,지현철,백태현,하장,Kong, Kyung-Hwan,Jee, Hyun-Chol,Baek, Tae-Hyun,Ha, Jang 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4
Objectives : It was designed for making theoretical base about the relation of the Spleen, Stomach and the liver which could be used in clinic. Methods : Including Huang Di Nei Jing(黃帝內經), the 22 kinds of books written about the relation of the Spleen, Stomach and the Liver, and 2 kinds of papers were referenced. They were divided and studied according to physiology, pathology, meridian system and treatment. This study is focused on internal organ theory. Conclusion 1. In physiology, the Liver has the function of smoothing and regulating the flow of vital energy(Ki), while the Spleen is in charge of digestion and transportation. 2. In pathology, there can be informed disharmony of the Spleen, Stomach and the Liver, blood deficiency in the Liver and Spleen, jaundice, and bleeding etc. 3. In meridian system, the junction points of Spleen Meridian and Liver Meridian are Liv14, SP6, SP12, SP13. 4. In treatment, 1) If there is disharmony of the Liver and Spleen, the Liver must be soothed and the function of Spleen invigorated. 2) If there is disharmony of the Liver and Stomach, the Liver must be soothed and the function of Stomach invigorated.
단시간의 경련성 실어증을 반복적으로 보이는 초점성 경련환자의 치험 1례
유희정,공경환,경혁수,Yoo, Hee-Jeong,Kong, Kyung-Hwan,Kyung, Hyuk-Su 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.4
Seizure can be categorized in various ways. Seizures are divided into those that are generalized and those affecting only part of the brain (focal seizure). Focal (partial) seizures are subdivided into simple seizures and complex seizures. Simple focal seizures may be manifested by focal motor, sensory or autonomic symptoms and consciousness is preserved. The above symptoms may be preceded, accompanied or followed by, and consciousness is impaired in, complex focal seizures. Ictal aphasia can arise from epileptiform discharge on cortical language areas. Generally next to the ictal aphasia, generalized seizures occur, but without losing consciousness, only aphasia takes place. A 61-year-old woman was admitted due to ictal aphasia and facial spasm, and she showed a little palpitation and was startled easily. We diagnosed her as Shimdamgiheo (心膽氣虛) and Damhwashimyo (痰火心擾), so we prescribed Chungsimondam-tang. It was effective on that case. so we report.
소뇌기능이상의 임상양상을 특징으로 보인 뇌교부출혈 환자 1례
이유경,공경환,용형순,고성규,부송아,Lee, You-Kyung,Kong, Kyung-Hwan,Yong, Hyung-Soon,Ko, Seong-Gyu,Bu, Song-Ah 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5
I experienced a case of a patient with clinical features of cerebellar dysfunction in the intracranial hemorrhage which encroached the basis of lower pontine and all parts of pontine tegmentum. So I report this case with bibliographical inquiry. In addition, I applied the treatment of Oriental medicine to sequelae of intracranial hemorrhage like disorders of eye movement, central dizziness, cerebellar tremor and ataxias but the effect did not meet my expectation. I anticipate more clinical studies and reports on this hereafter.
향사육군자탕(香砂六君子湯)의 Indomethacin 유발 위점막 손상에 대한 효과
백태현,공경환,Baik, Tae-Hyun,Kong, Kyung-Hwan 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4
Objective: This study was carried out to investigate the effects of Hyangsayukgunja-tang extract on indomethacin-induced gastric mucosal lesions of mice. Methods: To evaluate the effects of Hyangsayukgunja-tang extract and Misoprostol, the morphology of gastric mucosa, and the distribution of mucose cells, PNA(Peanut Agglutinin), ICAM(intercellular adhesion molecule), and apoptotic cells were observed. Hyangsayukgunja-tang extract and Misoprostol were intragastric injected to the test groups at hour 72 before and just before indomethacin treatment(HYT-J, HYT-72, M-J, M-72), while the INDO group was injected only with indomethacin and the control group was subcutaneously injected only with saline. Results: The gastric mucosal lesions incresed in the fundus and body of INDO group, but softened in HYT group and M group, the effects were more excellent in the HYT-72, M-72 groups than the HYT-J, M-J groups and in the HYT group than M group. The disappearance of surface and neck mucose cells were shown in INDO group, but softened in HYT group and M group. The mucosal configuration of HYT-72 group was the same as control group. The numerical increase of PNA positive reaction in cytoplasm of perietal cells were appeared in INDO group. The PNA positive reaction in HYT group and Miso-group were shown in surface mucous cells and microvilli of apical surface in chief cells as control group, and were the same as control group in all mucosa of HYT-72 group. The distribution of ICAM positive cells, increased in INDO group, but decreased in M-72 group, and were the same as control group in HYT-72 group. The apoptotic cells, increased noticeably in gastric mucosa of INDO group, decreased in HYT group and M group, and decreased noticeably in HYT-72 group. Conclusions: Hyangsayukgunja-tang extract had excellent effects on indomethacin-induced gastric mucosal lesions.
괴화산(槐花散)이 Dextran Sulfate Sodium으로 유도된 생쥐의 궤양성 대장염에 미치는 영향
배광호,공경환,Bae, Kwang-Ho,Kong, Kyung-Hwan 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3
Objectives : This study was carried out to investigate the effects of Goihwa-san(GHS) against ulcerative colitis induced by DSS (dextran sulfate sodium). Method : The sample group was divided into three. The control group consisted of mice that were not inflammation-induced. The pathological group was composed of untreated colitis elicited mice. The experimental group was administered GHS after colitis elicitation. The effects on ulcerative colitis were evaluated by the morphological change of colonic mucosa, the anti-oxidant effect, HSP 70, NF-${\kappa}$B, COX-1, COX-2 and iNOS. Results : In terms of immunohistochemical changes, the distribution of COX-1 in mice treated with GHS increased noticeably more than that in the pathological group. The distributions of HSP70, NF-${\kappa}$B, COX-2, iNOS in mice treated with GHS more decreased than those in the pathological group. Regeneration of surface epithelial cell and goblet cell in mucosa was observed by optical microscope. The colonic lengths in GHS-treated mice were more elongated than those of DSS only treated mice. Conclusion : GHS is a candidate treatment for ulcerative colitis.
DSS으로 유발된 생쥐의 대장점막손상에 대한 도체탕(導滯湯)의 효과
이주아,공경환,Lee, Ju-Ah,Kong, Kyung-Hwan 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.3
Objectives : This study was carried out to investigate the effects of Doche-tang on colonic mucosal ulcer induced by dextran sulfate sodium(DSS). Method : The group was divided into three. The normal group consisted of mice that were not inflammation-induced. The control group was composed of untreated colitis elicited mice. The sample group was administered Doche-tang after colitis elicitation. The effects on colonic mucosal ulcers were evaluated by the morphological change of colonic mucosa, the anti-oxidant effect, HSP 70, $NF-{\kappa}B$, COX-1, COX-2 and iNOS. Results : In terms of immunohistochemical findings, the distribution of COX-1 in mice treated with Doche-tang noticeably increased more than that in the control group. The distribution of HSP70, $NF-{\kappa}B$, COX-2, iNOS in mioe treated with Doche-tang decreased more than that in the control group. Regeneration of surface epithelial cell and goblet cell in mucosa was observed by transmission electron microscope. Conclusion : According to the results, Doche-tang is practicable treatment for colonic mucosal ulcer.
고호연,공경환,신미란,박선주,정희,고성규,선승호,이승언,이규광,윤병숙,이은용,Go, Ho-Yeon,Kong, Kyung-Hwan,Shin, Miran,Park, Sunju,Jung, Hee,Ko, Seong-Gyu,Sun, Seung-Ho,Lee, Seung-Eon,Lee, Kyugwang,Yoon, Byungsook,Lee, Eun-Yong 대한중풍순환신경학회 2009 대한중풍.순환신경학회지 Vol.10 No.1
Background and Objects : The environment of hospital have been changed rapidly. To adapt changes, it is needed to boost customer satisfaction. This study aims to investigate satisfaction of customer satisfaction program participants Method : After the one week customer satisfaction program was completed, we surveyed 50 participants. The questionnaire method was used in this study. The questionnaires item were sex, age, department, satisfaction, positive change, necessity and interval in customer satisfaction program. Results : The major results of the analysis were as follows Positive change after customer satisfaction program were 6.90±1.94. Necessity further customer satisfaction program were 7.74±2.09. Conclusions : Customer program should be needed and keep teaching to the staff.
중풍 환자의 경직에 있어서 전침 치료 효과에 대한 체계적 고찰
고호연,공경환,신미란,장명웅,박선주,박정수,장보형,이주아,고성규,전찬용,Go, Ho-Yeon,Kong, Kyung-Hwan,Shin, Mi-ran,Jang, Myung-Woong,Park, Sun-Ju,Park, Jung-Su,Jang, Bo-Hyung,Lee, Ju-A,Ko, Seong-Gyu,Jeon, Chan-Yong 대한중풍순환신경학회 2011 대한중풍.순환신경학회지 Vol.12 No.1
Background : Prevalence of spasticity because of stroke are 40% patients after 12 month. Spasticity caused decrease of range of motor, motor function, and active daily living. Electroacupuncture widely used stroke. But it is been studied by systematic review between spasticity and electroacupuncture. This study is aimed to efficacy of electroacupuncture for spasticity because of stroke. Methods : We had used pubmed(www.pubmed.com) and cochrane library(www.thecochranelibrary.com) database. Limits are'human','randomized controlled trial'and'all adult 19+ years'in pubmed. The period was until 15, september, 2011. We used MeSH(Medical Subject Headings terms. The search words were'stroke'[mesh],'muscle spasticity'[mesh and 'electroacupuncture'[mesh]. In cochrane library, we used spasticity and electroacupuncture in cochrane library. We found 19 studies. But only 3 studies were included for inclusion criteria. Results : The appropriate 3 studies were different from subject, acupoint, duration of treatment, endpoint and etc. But these studies were effective for spasticity because of stroke. Conclusion : These studies were not meta analysis because of heterogeneity. But the above results might explain the electroacupuncture were effective for spasticity and further study needed to verify and standard electroacupuncture study for spasticity.
하장,백태현,공경환,Ha, Jang,Baek, Tae-Hyeon,Kong, Kyung-Hwan 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.5
Objective : The study was to investigate Diagnosis and Treatment Based on an Overall Analysis of Signs and Symtoms(證治) of a patient on stomach cancer stage IV by means of the clinical symptoms. Methods : The observation of the clinical progress was carried out by conducting Diagnosis and Treatment Based on an Overall Analysis of Signs and Symtoms(證治) with the patient diagnosed stomach cancer stage IV. Results : Treatments such as the invigoration of qi(補氣), the flow of qi(行氣), and the relieving pain(止痛) was given because the patient showed the qi deficiency of the spleen and stomach(脾胃氣虛). There were moderate effects for anorexia, indigestion, nausea, and general weakness, but there was not any clear effect for alleviation of abdominal pain except the first period. Specially, compared with two hospitalization treatments in 1998, the third hospitalization treatment did not show any apparent improvement. It was believed that this caused by the patients bodily weakness because of deterioration of anemia from bleeding in the progress of cancer. Conclusion : Diagnosis and treatment based on an overall analysis of signs and symtoms(證治) of a patient on stomach cancer stage IV had moderate effects on the improvement of the patients condition, but in this case we had difficulty in long-term observation because of short hospitalizations or insufficient examination by an oriental-western combined medicine group.