괴화산(槐花散)이 Dextran Sulfate Sodium으로 유도된 생쥐의 궤양성 대장염에 미치는 영향

배광호,공경환,Bae, Kwang-Ho,Kong, Kyung-Hwan 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.3

Objectives : This study was carried out to investigate the effects of Goihwa-san(GHS) against ulcerative colitis induced by DSS (dextran sulfate sodium). Method : The sample group was divided into three. The control group consisted of mice that were not inflammation-induced. The pathological group was composed of untreated colitis elicited mice. The experimental group was administered GHS after colitis elicitation. The effects on ulcerative colitis were evaluated by the morphological change of colonic mucosa, the anti-oxidant effect, HSP 70, NF-${\kappa}$B, COX-1, COX-2 and iNOS. Results : In terms of immunohistochemical changes, the distribution of COX-1 in mice treated with GHS increased noticeably more than that in the pathological group. The distributions of HSP70, NF-${\kappa}$B, COX-2, iNOS in mice treated with GHS more decreased than those in the pathological group. Regeneration of surface epithelial cell and goblet cell in mucosa was observed by optical microscope. The colonic lengths in GHS-treated mice were more elongated than those of DSS only treated mice. Conclusion : GHS is a candidate treatment for ulcerative colitis.

그래프와 트리 구조를 활용한 한국어 문장제 수학 문제 풀이의 성능개선 연구

배광호,여상엽,정유철 한국정보과학회 2022 정보과학회논문지 Vol.49 No.11

In previous studies, there have been various efforts to solve math word problems in the English sentence system. In many studies, improved performance was achieved by introducing structures such as trees and graphs, beyond the Sequence-to-Sequence approaches. However, in the study of solving math problems in Korean sentence systems, there are no model cases, using structures such as trees or graphs. Thus, in this paper, we examine the possibility of solving math problems in Korean sentence systems for models using the tree structure, graph structure, and Korean pre-training language models together. Our experimental results showed that accuracy improved by approximately 20%, compared to the model of the Seq2seq structure, by introducing the graph and tree structure. Additionally, the use of the Korean pre-training language model showed an accuracy improvement of 4.66%-5.96%. 선행 연구에서 영어 문장제 수학 문제를 해결하려 한 다양한 시도가 있었다. 많은 연구에서 Sequence-to-Sequence(이하 Seq2seq) 패러다임을 넘어선 트리, 그래프 등의 구조를 도입하여 개선된 성능을 달성할 수 있었다. 하지만 한국어 문장제 수학 문제 풀이 연구에서는 트리(Tree)나 그래프(Graph)등으로 제안된 구조를 활용한 모델 사례가 없다. 이에 본 논문에서는 한국어 사전학습 언어모델을 사용하여 트리 구조를 활용하는 모델, 트리와 그래프 구조를 함께 활용하는 모델에 대한 한국어 문장제 수학 문제 풀이 능력의 가능성을 검토해보고자 한다. 테스트 결과 그래프와 트리 구조를 도입함으로써 Seq2seq 구조의 모델 대비 약 20%의 정확도 향상을 보였고, 나아가 한국어 사전학습 언어모델을 사용한 것이 사용하지 않은 것 대비 4.66~5.96%의 정확도 향상을 보였다.

사상체질에 따른 두통 특성 조사

배광호,박기현,이시우,안일구,김상혁 사상체질의학회 2023 사상체질의학회지 Vol.35 No.1

Objectives The study aimed to investigate the prevalence and characteristics of headaches according to Sasang constitution among 5,764 participants residing in Ansung or Ansan in Korea. Methods The Korea Sasang Constitutional Diagnostic Questionnaire was used to classify the constitution, and a self-administered questionnaire was used to collect headache data. The presence of headache, locations and patterns between groups were analyzed using the chi-square test and logistic regression adjusted for age, marital status, education, alcohol consumption, and smoking. Results Results showed that 25.6% of participants had headaches, with a significantly higher prevalence in Soeumin (30.8%) compared to Soyangin (24.9%) and Taeeumin (24.3%). Soeumin had significantly higher odds ratios for headaches than Taeeumin in both crude (1.387) and adjusted (1.319) models. Headache sites showed high frequency in the order of occipital (8.1%), temporal (8.0%), forehead (5.4%), and global regions (5.4%), and Soeumin showed significantly higher odds ratios of forehead (crude: 1.616, adjusted: 1.543) and occipital pain (crude: 1.366 adjusted: 1.379) compared to Taeeumin. No significant differences in headache patterns were observed among the groups. Conclusions This study suggests that Soeumin has a higher prevalence of headaches, particularly in forehead and occipital regions, compared to other Sasang constitutions. -

권두언

배광호 한국해사문제연구소 1982 (月刊)海洋韓國 Vol.106 No.-

N/A

책 쓰기 중심의 책 읽기 수업을 펼치다 : 꼬꼬북(책 읽고 책 쓰고) 프로젝트 수업

배광호 전국국어교사모임 2020 함께여는 국어교육 Vol.- No.137

건강 증진을 위한 평소 증상 기반의 한열변증 설문지 개발 - 일치도를 중심으로

배광호,윤영흠,여민경,김호석,이영섭,이시우,Bae, Kwang-Ho,Yoon, Youngheum,Yeo, Minkyung,Kim, Ho-Seok,Lee, Youngseop,Lee, Siwoo 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.2

Objectives : We presented the results of reliability study in advance, and analyzed agreement between Korean medicine doctors(KMDs)' diagnosis and cold-heat pattern identification questionnaire(CHPI)'s diagnosis. Methods : This survey was conducted from May 16 to 17, 2015. The subjects were 93 adults living in rural society. Diagnosis of CHPI was performed by 2 KMDs who have clinical experience more than 5 years. The KMDs' diagnosis was set as a reference index, and then we compare 23 items(cold pattern 11 items and heat pattern 12 items) of CHPI questionnaire and 15 items(cold pattern 8 items and heat pattern 7 items) that were brief form of it. We had cut-off value by standard of KMDs' diagnosis using receiver operating characteristic-curve(ROC-curve), with which we calculated agreement including kappa value. Correlation analysis between CHPI evaluation score by KMDs and by the questionnaire was fulfilled as well. Results : Agreement about 11 and 8 cold pattern items showed 87.1% together, and the value of kappa each recorded 0.742 and 0.741. Agreement about 12 and 7 heat pattern items suggested 81.7% and 78.5%, and the value of kappa showed 0.634 and 0.570. Correlation coefficients were 0.803 of 11 items and 0.761 of 8 items about cold pattern. In addition, correlation coefficients were 0.789 of 12 items and 0.767 of 7 items about heat pattern. The significant probability (p-value) was under 0.001. Conclusions : We have developed CHPI questionnaire involving reliability and agreement based on usual symptoms, and hope additional complements so that Korean medicine diagnostics and Korean preventive medicine would be improved.

사상체질에 따른 수부, 족부, 복부의 냉증

배광호,박기현,이시우 사상체질의학회 2018 사상체질의학회지 Vol.30 No.1

Objectives This study was aimed to examine cold hypersensitivity tendency in the hands, feet and abdomen according to Sasang constitution among Koreans. Methods Multi stage stratified sampling was conducted for random selection of 1,100 participants aged ≥ 19 years, based on sex, age, region in Oct.2010. Cold hypersensitivity was measured using a questionnaire to score the extent of cold hypersensitivity in the hands, feet, abdomen. Subjects’ constitution was diagnosed by Korea Sasang Constitutional Diagnostic Questionnaire (KS-15). The cold hypersensitivity scores according to Sasang constitution were analyzed using logistic regression and one way ANOVA. Results On the one way ANOVA, Soeumin group’s cold hypersensitivity in the hands and feet scores were significantly higher than those of Taeeumin and Soyangin groups. However, there was no significant difference in the abdominal cold hypersensitivity scores by constitution. The regression analysis, adjusted for age, sex, and sociodemographic variables, showed that Soeumin group had significantly higher cold hypersensitivity effects of the hands (β = 0.105, p = 0.002) and feet (β = 0.099, p = 0.003) than Taeeumin group. Conclusions Soeumin group significantly had higher cold hypersensitivity scores in the hands and feet than Taeumin and Soyangin group.

이원조론

배광호 한민족어문학회 1991 韓民族語文學 Vol.20 No.-

표고버섯 지면 봉지재배

배광호 충남대학교 농업생명과학대학 2007 논문집 Vol.- No.14

추적관찰을 통해 살펴본 한증 HRV지표

배광호,박기현,장은수 한의병리학회 2020 동의생리병리학회지 Vol.34 No.1

This study aimed to investigate heart rate variability (HRV) characteristics of cold pattern with repeated measurement data. Participants were taken from a Daejeon University cohort study from 2015 to 2018. Forty-seven of the participants studied displayed cold pattern while 23 showed signs of non-cold pattern. HRV was measured in supine position for 5 minutes at each year, and an 8-item cold pattern questionnaire was used for the diagnosis of cold pattern. SDNN (standard deviation of the NN intervals) and RMSSD (the square root of the mean squared differences of successive NN intervals) were used as time domain analysis, and TP (total power), VLF (power in very low frequency range), LF (power in low frequency range), HF (power in high frequency range), LF norm (LF power in normalized units), HF norm (HF power in normalized units) and LF/HF were used as frequency domain analysis. In the Mann-Whitney U test, LF norm, HF norm, and LF/HF showed differences between the cold pattern group and non-cold pattern group at every measurement, and in the independent t-test, the differences were also observed at three points except for the baseline (2015). In the repeated measures ANOVA, the interaction effects were not observed in all HRV parameters, but the time period effects were observed in SDNN, RMSSD, TP, VLF, LF and HF. There were significant differences between those two groups in LF norm, HF norm and LF/HF. This study suggests that LF norm, HF norm and LF/HF might be a useful indicator of cold pattern properties.