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황준기,서경도,신교민,임형석,조준철,김진웅 한국고분자학회 2012 Macromolecular Research Vol.20 No.4
This study describes the effect of conductivity on the electrorheological (ER) behavior of anisotropic particle suspensions. Anisotropic microparticles were prepared by two-step seeded polymerization. To control the particle conductivity, functionalized multi-wall carbon nanotubes were coated on the particle surface via a layer-bylayer (LBL) method. Particle conductivity increased with layer numbers and the yield stress of the fluids increased with increasing electric field strength. However, the yield stress decreased when suspended particle conductivity increased. Although high conductivity allowed high particle polarization ability, field-induced ER fluid viscoelastic properties decreased.
황준기,Hyounggyoon Yoo,Ji Won Lee,Geun Seog Song,SeungHwan Lee,김민걸 대한임상약리학회 2019 Translational and Clinical Pharmacology Vol.27 No.2
Proton-pump inhibitors (PPIs) are effectively used to treat acid-related diseases, including gastroesophageal reflux disease (GERD); however, many unmet medical needs still exist. As a new treatment option, potassium-competitive acid blockers (P-CABs), such as tegoprazan, have been developed. This study was performed to compare the pharmacokinetics (PKs) between two formulations (test and reference drugs) of tegoprazan 100 mg tablets. A randomized, single oral dose, two-treatment, two-period, two-sequence study was conducted with 12 healthy subjects. Each subject received the test drug or reference drug in the first period and the alternative treatment in the second period. For PK evaluation, blood samples were collected up to 48 hours post-dose in each period. The plasma concentrations of tegoprazan and its active metabolite (M1) were measured by liquid chromatography-tandem mass spectrometry. PK parameters, including maximum plasma concentration (Cmax) and area under the concentration-time curve from zero to the last measurable time (AUClast), were estimated using a non-compartmental method. The plasma concentrationtime profiles of the two formulations were comparable. The geometric mean ratios [90% confidence intervals (CIs)] of the test drug to the reference drug for Cmax and AUClast were 0.98 (0.85–1.12) and 1.03 (0.93–1.13), respectively. The corresponding values of M1 were 0.99 (0.89–1.11) and 1.01 (0.93–1.09), respectively. The two formulations of tegoprazan exhibited comparable PK profiles, fulfilling the regulatory criteria for bioequivalence.
황준기,서경도 한국고분자학회 2019 Macromolecular Research Vol.27 No.6
This work details the facile preparation of a hexagonally ordered monolayer electrode with monodispersed hollow C/Fe3O4 microspheres as a novel anode candidate for lithium-ion batteries. The monolayer electrode was produced by the heat treatment of a polyvinyl alcohol film comprising a monolayer of microspheres. The electrode was prepared by stamping with microspheres assembled into the monolayer, using an ordered patterning micro-framework polydimethylsiloxane on a polyvinyl alcohol spin-coated cupper foil. The morphological and structural characterizations of the monolayer electrode were conducted by optical microscopy, scanning electron microscopy, focused-ion beam scanning electron microscopy, transmission electron microscopy, and X-ray diffractometery. Although the monolayer electrode was composed of the active materials only without the use of any polymeric binder or carbon additives such as acetylene black and Super-P, the electrode exhibited a superior long-term cycling stability and rate capability with the coulombic efficiency of 99% at a high current rate due to the good structural stability and low electrical resistance as a result of the ordered monolayer structure.
점자 색채지도자료와 CAI배색프로그램 교수가 시각장애학생 배색정확성에 미치는 효과
황준기,박희찬 韓國視覺障碍硏究會 2000 시각장애연구 Vol.16 No.-
This study was designed to increase the visually impaired students' learning effectiveness on the session of hue, by examining the progressive change of coloring accuracy of the visually impaired students group those who had learned hue circle and color solid, in the session of hue, and colored with CAI(Computer Assisted Instruction) coloration program, in comparison to that of the other controlled students group, those who had learned same subject by traditional coloring method with standard coloration methods. Subjects were selected 40 visually impaired middle school & high school students in Inchon and were divided 4 groups; experimental blind students group, experimental low-visioned students group, controled blind students group, and controled low-visioned students group. The results of this study were as follows. First, accuracy of coloration of experimental group that had learned hue circle and color solid of braille materials with a CAI coloration program-increased in comparison to that of control group that had learned and colored them with standard materials for normally sighted students. Second, accuracy of coloration of experimental blind group that had learned hue circle and color solid of braille materials with a CAI coloration program increased, in comparison to that of controlled blind group. Third, accuracy of coloration of experimental low-visioned students group that had learned hue circle and color solid of braille materials with a CAI coloration program increased, in comparison to that of controlled low-visioned group. Fourth, there was no sufficient difference between experimental blind group and experimental low-visioned group that had learned hue circle and color solid of braille materials with a CAI coloration program.