http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
1-(Benzotriazol-1-yl)alkyl Aryl Sulfone의 합성
홍영석,김현묵,이정근,박용태,김호식,Hong, Young Seuk,Kim, Hyun Muk,Lee, Jeong Geun,Park, Yong Tae,Kim, Ho Sik 대한화학회 1996 대한화학회지 Vol.40 No.9
1-(Benzotriazol-1-yl)-1-benzenesulfonylmethane 1a에 LDA 및 methyl iodide를 작용시켜 1-(Benzotriazol-1-yl)-1-benzenesulfonylmethane 2a와 2-(Benzotriazol-1-yl)-2-benzenesulfonylpropane 2b를 각각 얻었다. 같은 방법으로 1-(Benzotriazol-1-yl)-1-benzenesulfonylmethane 1b로부터 1-(Benzotriazol-1-yl)-1-benzenesulfonylpropane 3a와 3-(Benzotriazol-1-yl)-3-benzenesulfonylpentane 3b를 얻었다. 한편, 1, 1-di(benzotriazol-1-yl)-1-arylmethane 4를 butyl lithiym과 diphenyl disulfide로 처리하여 1, 1-di(benzotriazol-1-yl)-1-aryl-1-thiophenoxymethane 5를 합성하였다. 1, 1-di(benzotriazol-1-yl)methane 8을 butyl lithiym과 diphenyl disulfide로 처리하여 1, 1-di(benzotriazol-1-yl)-1-thiophenoxymethane 9a와 1, 1-di(benzotriazol-1-yl)-1, 1-dithiophenoxymethane 9b를 각각 얻었다. 화합물 9a를 m-CPBA로 산화시켜 1, 1-di(benzotriazol-1-yl)-1-benzenesulfoxymethane 10a와 1, 1-di(benzotriazol-1-yl)-1-benzenesulfonylmethane 10b를 얻었다. 한편, 화합물 3b를 170.deg.C 에서 열분해시켜 3-toluenesulfonyl-2-pentene 11ㅇ르 얻었으며, 150.deg.C의 강철봄베속에서 3b를 과량의 물로 가수분해 시켰더니 sulfone의 C-N 및 C-S 결합 모두가 절단된 diethyl ketone 13a가 생성됨을 확인하였다. (Benzotriazol-1-yl)arenesulfonylalkanes, 2a, 2b, 3a and 3b, were prepared by lithiation of 1-(benzotriazol-1-yl)arenesulfonylmethanes followed by reaction with alkyl iodides. Very bulky molecules such as 1,1-di(benzotriazol-1-yl)-1-aryl-1-thiophenoxymethanes 5, 1,1-di(benzotriazol-1-yl)-1-thiophenoxymethane 9a and 1,1-di(benzotriazol-1-yl)-1,1-dithiophenoxymethane 9b were synthesized. 1,1-Di(benzotriazol-1-yl)-1-benzenesulfoxymethane 10a and 1,1-di(benzotriazol-1-yl)-1-benzenesulfonylmethane 10b were also synthesized by the oxidation of compound 9a, while oxidation of sulfide group on compound 5 and 9b by m-CPBA were not successful. On the other hand, pyrolysis and hydrolysis of 3-(benzotriazol-1-yl)-3-toluenesulfonylpentane 3b gave 3-toluenesulfonyl-2-pentene 11 and diethyl ketone 13a, respectively, which means there are both C-N and C-S bond cleavages.
洪永錫 啓明大學校 生活科學硏究所 1976 科學論集 Vol.3 No.-
새로 합성한 cis-2-butenedialdioxime의 形態(conformation)를 NMR, 확장분자궤도법(EHT) 및 비등방성효과에 대한 Pople의 model을 사용하여 결정하였다. 이 物質은 두 개의 炭素一炭素 單一結合이 炭素一炭素 二重結合의 여섯 sp²혼성궤도가 이루는 平面에서 같은 방향으로 약 25°C 회전된 形態임을 알았다. Conformation of cis-2-butenedialdioxime, a newly synthesized compound, was assigned by means of nuclear magnetic resonance, extended Huckel molecular orbital method, and Pople's model of anisotropic effect. It was confirmed that two carbon-carbon single bonds are conrotatory twisted from the molecular plane of six sp² orbitals of carbon-carbon double bond. The conformation of minimum energy is found to be twisted by 25°.