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포상연부육종의 세침흡인 세포학적 소견 - 1예 보고 -
한혜승,박인서,한지영,김준미,김영배,황태숙,주영채,Han, Hye-Seung,Park, In-Seo,Han, Jee-Young,Kim, Joon-Mee,Kim, Young-Bae,Hwang, Tae-Sook,Chu, Young-Chae 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.2
Alveolar soft part sarcoma is a rare soft tissue tumor. Few cases on fine needle aspiration cytology have been reported in the literature. We experienced a case of recurrent alveolar soft part sarcoma of the right thigh diagnosed by fine needle aspiration cytology in a 47-year-old man. Cytologic findings showed single cells and clusters associated with thin wailed vasculature in a distinct pseudo-alveolar pattern. The tumor cells exhibited round or ovoid abundant granular cytoplasm and large pleomorphic nuclei with prominent central nucleoli.
한혜승 ( Seung Han Hye ) 대한내과학회 2014 대한내과학회지 Vol.87 No.3
Pancreatic cystic lesions are being recognized with increasing frequency due to the development of imaging technologies. Pancreatic cystic lesions can be divided into neoplasms and non-neoplasms, and neoplasms can be further categorized as epithelial and non-epithelial tumors depending on the cells of origin. A significant percentage of pancreatic cystic neoplasms have malignant potential and surgical resection is mandatory. To make the proper decision regarding the management of pancreatic cystic neoplasms, it is important to understand the clinicopathologic features of these tumors. (Korean J Med 2014;87:270-278)
한혜승(Hyeseung Han),이주경(Joo-Kyeong Lee) 한국음성학회 2007 음성과학 Vol.14 No.4
This paper attempts to verify the theoretical claims in Syntax (Bo?kovi? & Lasnik, 2003; Kim, 1999, 2004) about the phrasing in English that-clauses, presenting an acoustic experiment conducted to observe the patterns of edge tones at the boundaries of that. In the experiment, two different that clauses, complement and relative clauses, were varied in forms (that-retention, that-deletion, adverb insertion before that) and length. Results showed that edge tones, if occurred, mostly showed up before the complement clauses in that-deletion sentences (67%), and that their positions polarized in adverb insertion sentences (56% before that and 44% after that). In the relative clauses, phrasing mostly occurred before that as opposed to after that in that-retention (73%) and adverb insertion sentences (87%). Additionally, phrasing tends to occur more frequently as the sentences get longer. The results suggest that the previous claims based on syntax are not consistent with the results of the current phonetic experiment. This may be interpreted as stating that syntactic boundaries do not always indicate phonetic phrasing, and that there may be some other factors to determine phrasing patterns, for example, rhythmic phrasing operating at the surface level of speech.
대장 종양에서의 Sonic Hedgehog 단백의 발현
한혜승 ( Hye Seung Han ),이선영 ( Sun Young Lee ),성무경 ( Moo Kyung Seong ),김정환 ( Jeong Hwan Kim ),성인경 ( In Kyung Sung ),박형석 ( Hyung Seok Park ),진춘조 ( Choon Jo Jin ),황태숙 ( Tae Sook Hwang ) 대한장연구학회 2008 Intestinal Research Vol.6 No.1
Background/Aims: Dysregulation of the hedgehog pathway has been implicated in regeneration and carcinogenesis, leading to the expression of the sonic hedgehog (Shh) protein in gastrointestinal neoplasms. The expression of Shh in colon neoplasms and paired normal colonic mucosa was therefore investigated. Methods: Forty-four colon cancers and 73 colon adenomas that were removed by surgical colectomy or colon polypectomy between August 2005 and August 2006 were included. Colorectal neoplasms and the adjacent normal colon tissue were examined by immunohistochemistry using rabbit polyclonal Shh antibody. Results: Expression of Shh was up-regulated in adenomas and adenocarcinomas of the colon compared to normal colon tissues (p<0.001). The degree of Shh expression was not associated with the size, shape, or, location of the tumor, or as the age and gender of the patient. In normal colonic epithelium, Shh was expressed at the apex of the crypts and in a few basally-located cells. Conclusions: Higher levels of Shh expression in colonic adenoma and adenocarcinoma suggest that Shh is required during epithelial proliferation in the colon. Hedgehog signaling is likely to be associated with early tumorigenesis in colonic neoplasms. (Intest Res 2008;6:19-24)
한혜승 ( Hye Seung Han ),이주경 ( Joo Kyeong Lee ) 현대영어교육학회 2008 현대영어교육 Vol.9 No.3
This paper attempts to investigate the phrasing patterns in Korean speakers` production of English that-clauses For this, the patterns of Koreans were compared with those of English native speakers through the acoustic experiment. The tonal phrasing patterns of two different that-complement clauses and that-relative clauses were examined in terms of the phrase accents and boundary tones. Two kinds of that clauses which are complement and relative clauses, are used in three forms such as that-retention, that-deletion, and adverb insertion before that. Both advanced learners and beginners of English participated in the experiment. In the case of the advanced, their phrasing patterns are similar to those of native speakers in that they distinguish complement clauses from relative ones with making no phrase after that in the relative clauses. However, advanced learners` frequency of phrasing was comparatively low, which can be interpreted as stating that they focus more on reading English sentences than comprehension. In the case of beginners, their local phrasing in the relative clauses was considerably different from native speakers` such that they frequently put phrase boundaries after that. Also, at the level of global phrasing, they produce comparatively more phrases over a whole sentence.
조직 미세배열법을 이용한 비소세포 폐암 조직에서 에스트로겐과 프로게스테론 수용체 발현
한혜승 ( Hye Seung Han ),김민지 ( Min Ji Kim ),조재화 ( Jae Hwa Cho ),윤용한 ( Yong Han Yoon ),곽승민 ( Seung Min Kwak ),이홍렬 ( Hong Lyeol Lee ),김광호 ( Kwang Ho Kim ),류정선 ( Jeong Seon Ryu ) 대한결핵 및 호흡기학회 2005 Tuberculosis and Respiratory Diseases Vol.58 No.1
연구 배경 : 비소세포 폐암의 암화 과정에서 에스트로겐과 프로제스테론 단백의 역할에 대한 면역조직화학 염색을 이용한 연구들이 진행 중이다. 그러나 이 연구들은 아직 일치된 결과를 보이고 있지 않으며 이는 상용하는 면역조직화학 염색법이 한 문제로 제시되고 있다. 저자 들은 최근 새로 개발된 조직미세배열법을 이용하여 비소세포 폐암 환자의 조직에서 이들 호르몬 수용체 발현을 연구하였다. 대상 및 방법 : 대상은 70예의 비소세포 폐암 환자로 남성이 74%, Background : To evaluate the role of estrogen and progesterone in the carcinogenesis of NSCLC, IHC studies for the expression of the receptors of estrogen and progesterone have been performed with inconsistent results. Recently the TMA method has been dev
한혜승(Han, Hyeseung),이주경(Joo-Kyeong Lee) 한국음운론학회 2009 음성·음운·형태론 연구 Vol.15 No.3
Han, Hye-seung, and Joo-Kyeong Lee. 2009. Prosodic features in the English phrases including particles, adverbial prepositions and prepositions. Studies in Phonetics, Phonology and Morphology 15.3. 499-514. This study attempts to investigate prosodic features in the English phrases including particles, (e. g., the second element in a verb phrase such as give up the exam), adverbial prepositions (e. g., the second element of jump off the wall) and prepositions (e.g., the second element of study in the room). A phonetic experiment was conducted to see if there are any differences and /or prosodic structures among those three phrases. The stimuli were varied with two different objects, noun and pronoun and two kinds of rate, slow and fast, and pitch accent distribution and phrasing were measured within the phrases. Results showed that pitch accents were very frequently realized on both the particles and the adverbial prepositions, but that prepositions were rarely implemented a pitch accent. When the objects were a pronoun, a pitch accent consistently moved to particles, adverbial prepositions, and prepositions. Moreover, there are more phrase involved in the boundaries of the particle + the following noun phrase and the preceding verb + adverbial preposition and the adverbial preposition + the following noun phrase. It was interpreted as stating that such patterns reflect the differences in semantic weight among the three elements and the degree of semantic cohesion with the preceding verbs and the following noun phrases, and that adverbial phrases show distinct prosodic features from both particles and prepositions. This suggests that adverbial prepositions should constitute their own category semantically and/or prosaically. (University of Seoul)