사람을 다시 살리는 일, 간병노동 ①

차승희 한국비정규노동센터 2013 비정규 노동 Vol.- No.101

국내 가와사키병 환아의 약물사용

차승희,제남경 한국임상약학회 2017 한국임상약학회지 Vol.27 No.3

Background: Kawasaki disease (KD) is an acute febrile, systemic vasculitis as a leading cause of acquired heart disease in children. Intravenous immunoglobulin G (IVIG) and aspirin are the standard initial therapy in the treatment of acute KD. The purpose of this study was to investigate drug utilization in children with KD, and to compare “IVIG + high-dose aspirin” and “IVIG + moderate-dose aspirin” in preventing cardiac complications. Methods: We analyzed pediatric patient sample data compiled by the Health Insurance Review & Assessment Service from 2010 to 2015. We identified patients with KD using the KCD-6 code of M30.3. We excluded patients in chronic phase or ≥10 years. We also excluded patients who were diagnosed KD in November or December. Drug utilization pattern were assessed in acute KD patients and 30-day and 60-day cardiac complications were investigated between “IVIG + high-dose aspirin” group and “IVIG + moderate-dose aspirin” group. Results: In acute phase, IVIG was administered to 95.8% patients, and 57.1% patients were prescribed moderate-dose aspirin and 25% patients were with highdose aspirin. Steroid use was rapidly increased from 4.0% in 2010 to 11.3% in 2015. Both 30-day and 60-day cardiac complications occurred less in “IVIG + high-dose aspirin” group compared to “IVIG + moderate-dose aspirin” group, but not statistically significant (0.9% vs 1.8%, p=0.252 for 30-day complication rate; 1.5% vs 2.7%. p=0.073 for 60-day complication rate). Conclusion: We were not able to demonstrate which aspirin therapy is superior for preventing cardiac complications in acute KD patients and further research is warranted.

패션마케팅분과 2 : 소비자의 쇼핑성향과 점포분위기에 따른 정서적 반응이 충동구매에 미치는 영향

차승희,이선재 한국의류학회 1999 한국의류학회 학술대회논문집 Vol.1999 No.1

Detection of Salmonella Group with Monoclonal Antibodies

차승희,오상곤,김지천,윤희주,정윤수,Cha, Seung-Hee,Kim, Sang-Kon,Kim, Jee-Cheon,Yun, Hee-Ju,Jung, Yun-Su Korean Society for Biochemistry and Molecular Biol 1989 한국생화학회지 Vol.22 No.1

열처리된 Salmonella typhimurium 세포를 이용하여 Salmonella에 대한 단일클론성 항체를 생산하는 hybridoma 3종을 얻었다. 3종의 hybridoma는 각각 다른 항체 IgG1 k, IgG2a k, IgM을 생산하였으며 이들 항체는 EIA로 Salmonella와 다른 세균들에 대한 특이성을 검토하였다. IgG1 k 항체는 시험된 Salmonella균과 Enterobacter clocae 및 몇종의 E. coli strain과 친화성이 있었으며 IgM항체는 대부분의 세균에 대해서 친화성을 나타내었다. IgG2a k 항체는 Salmonella strain과 E. coli strain B에 약한 친화성을 나타내었다. IgG2a k 항체는 modified double antibody sandwich EIA에서 Salmonella 항원을 $5{\times}10^3cells/ml$ 농도까지 검출 가능하였으며 항체역가는 mouse 복수액에서 $5{\times}10^4$이었다. Monoclonal antibodies were produced against whole cells of heat treated Salmonella typhimurium. From the Balb/c mice immunized, 164 hybridomas were obtained. Of 164 hybridomas, six reacted with all three species of Salmonella; three were cloned. Monoclonal antibodies from three hybridomas were characterized to belong to IgG1 k, IgG2a k, IgM subclass respectively. Among them, IgG2a k revealed the most specific reactivity of Salmonella species tested, even though reacted weakly with one of E. coli strains, whereas IgGl k and IgM were found to cross react with some strains of Enterobacteriaceae. By using a modified double antibody sandwich EIA together with IgG2a k, a minimum level of cells of Salmonella species detected was estimated $5{\times}10^3$ cells/ml. Antibody titer of IgG2a k in ascite fluids was $5{\times}10^4$.

SEDPAK을 이용한 동해 울릉분지 남서연변부 퇴적분지의 진화과정 복원과 저류층 특성화를 위한 예비 연구

차승희,정대교 대한지질학회 2009 대한지질학회 학술대회 Vol.2009 No.

초등학교 이러닝 콘텐츠의 학습 유효성 평가 방법에 관한 연구

차승희,김현배 한국정보교육학회 2005 정보교육학회논문지 Vol.9 No.2

최근 교육의 전 부분에서 이러닝(e-learning)이 도입되고 있고, 또 빠른 속도로 확장되어가고 있다. 이 러닝과 함께 새로 대두되는 통합형 학습(blended learning)은 오늘날의 교육이 좀 더 새로운 형태의 교육패러다임으로 변화하고 있다는 것을 보여주는 한 예이다. 본 논문은 앞서 연구된 여러 이러닝 콘텐츠 평가 준거들을 살펴보고, 초등학교 교사들을 대상으로 실시한 설문을 통해 초등학교에서 이러닝 콘텐츠의학습유효성을 평가할 수 있는 평가 문항으로 정리하였다. 그리고 이 평가 문항과 학습자의 학업성취도 결과를 이용하여 이러닝 콘텐츠의 학습유효성 평가에 적용해보았다. 본 연구는 초등학교 이러닝 콘텐츠의평가준거와 평가 방향에 대한 논의를 공유하며, 더 나아가 통합형 학습의 질적 향상을 위한 양질의 이러닝 콘텐츠 개발을 위한 이론적이고 실무적인 자료를 제공하고자 하는데 의의가 있다. e-learning has been recently introduced in all educational domains and it has expanded rapidly in educational field. Blended learning, which has emerged with e-learning nowadays, is an exact example of a new paradigm. It has not only educational effects of traditional classroom learning, but it also has effects of e-learning which provides learner-centered classroom environment and removes barriers of time and space. This study looked into several e-learning contents evaluation criteria that were already studied, And arranged with the evaluation question item that can evaluate learning effectiveness of e-learning contents in elementary school through a questionnaire executed in elementary school teachers. And it used this evaluation question item and the study accomplishment results of an education ruler, and applied to learning effectiveness evaluation of e-learning contents. This paper will give future directions and assessment criteria of e-learning. Moreover, this thesis will provide theoretical and practical materials for developing e-learning contents to improve quality of blended learning.

[The Therapy] 이완을 위한 요가

차승희 계간 미술치료 2018 계간 미술치료 Vol.- No.10

사람을 다시 살리는 일, 감정노동②

차승희 한국비정규노동센터 2013 비정규 노동 Vol.- No.102

MicroRNAs in Autoimmune Sjögren’s Syndrome

차승희,Mahmoud Mona,이경은,김동희,한규동 한국유전체학회 2018 Genomics & informatics Vol.16 No.4

MicroRNAs (miRNAs), small non-coding RNAs, have been implicated in various diseases and cellular functions as microregulators of gene expression. Although the history of miRNA investigation in autoimmune Sjögren’s syndrome (SjS) is fairly short, a substantial amount of data has already been accumulated. These findings clearly indicate potential clinical implications of miRNAs, such as autoantigen expression and autoantibody production, viral miRNAs regulating the calcium signaling pathway, and aberrant immune cell regulation and cytokine production. Research endeavors in the field are currently underway to select disease-specific diagnostic and prognostic biomarkers by utilizing different types of tissues or biological specimens of SjS patients. Various techniques for miRNA analysis with different stringencies have been applied, with the most recent one being next-generation sequencing. This review compiles and highlights differentially-expressed miRNAs in various samples collected from SjS patients and their potential implications in the pathogenesis of SjS. To facilitate the development of miRNA-targeted personalized therapy in the future, we urge more follow-up studies that confirm these findings and elucidate the immunopathological roles of differentially-expressed miRNAs. Furthermore, improved diagnostic criteria for the disease itself will minimize sampling errors in patient recruitment, preventing the generation of inconsistent data.

조각보에 나타난 한국 버나큘러 색채의 활용 현황에 대한 연구

차승희,문철 숙명여자대학교 산업디자인연구소 2011 숙명디자인학 연구 Vol.15 No.-

전세계적으로 각 나라마다 고유색의 전통은 국민적 정서, 환경, 토양 등을 토대로 이루어진다. 또 공공화하기까지는 무조건적 선진화가 아닌 가치관의 추구, 국민적 공감대 형성, 문화권에의 흡수 등 시대적 흐름이 수반되어야 한다. 본 논문의 목적은 이런 시대의 흐름을 배경으로 한국의 버나큘러적인 색채가 우리의 생활 속 전통 거리에 적절히 활용되어 한국적 이미지를 잘 나타내었는지에 대한 현황 분석에 있다. 따라서 사례연구는 과거와 현재로 나누어서, 조선시대 조각보와 인사동을 중점적으로 다루었다. 조각보와 인사동 거리의 색채를 측정하기 위해 NCS 색표집을 이용하여 근접거리에서 육안비색법을 실시하였다. 연구 분석 결과, 조선시대 조각보는 색채의 경계 없이 저채도에서 고채도에 이르는 폭넓은 색채를 사용하였음을 알 수 있었다. 간판 색채는 조각보와 유사한 색채 분포를 나타냈으며 이것은 주목성을 높이기 위한 결과물이다. 하지만 인사동 거리는 일반적인 도시의 거리와 별 차이 없이 저채도의 제한된 색채를 사용했음을 알 수 있었다. 본 논문은 조각보를 시작으로 서민의 생활 속에서 다양한 매체들의 색채를 조사하여 향후 공공 거리에서 주체성 있는 한국적인 이미지를 나타내기 위한 방안을 마련하는 데 기초자료로 활용할 것이다. 그리고 전통 공간에서 한국적 이미지를 살리기 위한 구체적인 색채 배색을 제안하는 연구로 심화 발전시켜 나갈 것이다. The tradition of the native color of each country of the world is based on national emotion, environment and s oil. To make this tradition to be public, the current of time such as the pursuit of value, the formation of national sympathy and absorption to the culture area should be accompanied more than unconditional advancement. The purpose of this paper is to recognize such a revival as the flow of the times, and analyze whether Korea n traditional image has been well expressed through proper utilization of Korean traditional and popular color in public streets. So, case study has been conducted by using past and present sample: the past sample is the patchwork wrapping-cloth and Insa-dong. To measure color characteristics of patchwork wrapping-cloth and In sa-dong street, macro-colorimetric method was used with the NCS color system at a close range. Results of res earch and analysis say that wide range of colors without boundaries, from low-chroma colors to high-chroma colors, were used for making patchwork wrapping-cloth of Joseon. The distribution style of colors on signboards was similar to that of patchwork wrapping-cloth, and t his is the result to heighten the attention effect. However, I found that limited low-chroma colors were used i n Insa-dong street as used in general urban streets. This research paper will be used as basic document to arrange the method to express Korean image subjective in the public street after researching the colors of diver se objects in common people`s life starting from patch work wrapping-cloth. In addition, I will develop this research to the research that suggests the specific color distribution to show the Korean image in the traditional space.