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조항철(Han C. Cho) 한국예방수의학회 1988 예방수의학회지 Vol.12 No.1
광견병 예방백신의 발달과정 및 종류별 성상에 관하여 종합적으로 고찰하였다. 본문은 사람 및 가축에 있어서의 예방백신에 관한 고찰과 야생동물에 대한 면역에 관련된 사항을 다루었다. 본문의 요지는 한국수의공중보건학회 1987년도 총회에서 특강자료로 발표한 바 있다. The association of rabies in man with the disease in dogs has been known since ancient times. Carnivores generally constitute an enzootic reservior. Man and all warm -blooded animals are susceptible to the disease. Natural infection in man is always related to exposure to a rabid animal and the onset of symptoms may vary from days to many months and possibly years. Variation in the incubation period depends largely upon the site and severity of injury and the amount of infectious virus transferred at the time of exposure. Mortality in untreated cases approaches 100% in man and treatment is ineffective after symptoms have appeared. Rabies vaccine injected before exposure or within a short time after exposure can prevent the development of disease.
Metallothionein 유전자를 활용한 제주배꼽달팽이(Aegista chejuensis)의 분자계통학적 연구
박지은,조항철,황희주,정종민,상민규,민혜린,강세원,박소영,Bharat Bhusan Patnaik,김완종,한연수,이준상,이용석 한국패류학회 2018 The Korean Journal of Malacology Vol.34 No.1
Metallothioneins (MT) are cysteine-rich small proteins known for their high affinity binding to metal ions. MT confers cytoprotection against oxidative stress and acts as an efficient modulator of immunity and infection. There have been ever-increasing reports on the function of MT in environmental monitoring programmes. Lately, MT has been studied as a biomarker towards the taxonomic clustering of various species, including the molluscans. The Korean endemic land snail, Aegista chejuensis is native to Jeju Island and South coastal regions of Korea. Functional genomics information for the species is limited, although the Illumina-based DNAseq and transcriptome information are registered with the Sequence Read Archive (SRA) of National Center for Biotechnology Information (NCBI). While annotating the ORF-sensitive unigenes from the transcriptome, a MT sequence comprising of 288 bp coding region and 96 amino acid residues translatable protein was deciphered. In silico analysis using ClustalX and the MEGA7 program grouped A. chejuensis under the Stylommatophora clade of eupulmonate mollusk families. The study was able to confirm the evolutionary position of the species and established the MT sequence as a candidate for taxonomic classification of the species.