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조병식 ( Byoung Sik Cho ),곽승기 ( Seung Ki Kwok ),서영일 ( Young Il Seo ),민도준 ( Do June Min ),김완욱 ( Wan Uk Kim ),이숙경 ( Suk Kyoung Lee ),박성환 ( Sung Hwan Park ),조철수 ( Chul Soo Cho ),김호연 ( Ho Youn Kim ) 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.4
Rheumatoid arthritis(RA) is occasionally associated with variable extra-articular involvement and the chronic inflammatory process can affect the gastrointestinal system. The gastrointestinal involvement in RA may present in many causes: drug induced colitis, vasculitis and amyloidosis involved in the gut, association with certain bowel diseases such as collagenous colitis or infectious colitis. Ulcerative colitis(UC) is a chronic inflammatory bowel disease and is commonly associated with peripheral joint disease which correlates with the disease activity and extent of the bowel inflammation. The arthritis is usually presented in pauciarticular, generally asymmetric, transient, and nondestructive pattern. However, the chronic and destructive peripheral arthritis has been reported in a few cases and RA has not been observed in association with UC. We experienced a case of RA patient with recurrent abdominal pain, hematochezia, and tenesmus who was diagnosed as UC by endoscopic and histologic finding. We herein report the case with literature.
무증상 세균뇨를 보인 당뇨병 환자에서 발견된 기종성 신우신염 1예
조병식,손현식,이정민,안유배,윤건호,강무일,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.2
기종성 신우신염은 주로 당뇨병 환자에서 드물게 발견되는 심한 감염성 질환으로 저자들은 무증상 세균뇨를 보인 당뇨환자에서 복부초음파, 복부 전산화 단층촬영으로 확인된 기종성 신우신염 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The emphysemotous pyelonephritis is on uncommon, but life-threatening, severe renal infection characterized by the presence of gas in the renal parenchyma or perinephric space. The prompt diagnosis and early treatment is important in the prognosis of the disease. The disease is encountered mainly in patients with uncontrolled diabetes mellitus and/or obstructive uropathy, etc. The mortality rate of patients treated conservatively approaches approximately 80% in some series. These patients often present with signs of sepsis or septic shock. We experienced a case of diabetic patient with asymptomatic bacteriuria who was diagnosed as emphysemotous pyelonephritis by abdominal ultrasonogram and CT scanning. It was caused by Klebslella pneumoniae and treated by medical treatment alone. We herein report the case with literature.
고위험군의 원발성 전신성 유전분증 1례 보고 및 조혈모세포이식에 대한 문헌고찰
심준,박수정,엄현석,김기영,박은정,강인중,조병식,이안희,한치화 대한조혈모세포이식학회 2001 대한조혈모세포이식학회지 Vol.6 No.2
저자 등은 클론성 형질세포질환과 동반된 젊은 연령의 원발성 전신성 유전분증 환자를 진단하였기에 다발성 골수종과의 감별 진단, 치료 , 예후 및 고용량 항암화학요법과 조혈모세포이식에 관하여 문헌고찰과 함께 보고하는 바이다. Primary systemic amyloidosis (AL) is a rapidly fatal disorder related to plasma cell dyscrasia. Conventional dose of melphalan, which prolongs the duration of survival by about 10 months, does not improve the functions of impaired organs in most cases. The high dose chemotherapy followed by autologous hematopoietic stem cell rescue for AL, in spite of its high treatment-related mortality, is a new approach to achieve high response rate and better survival. We experienced a 35-year old man with AL(involving heart, liver, stomach, kidneys, peripheral nerve, and rectum) who did not respond to the standard schedule of melphalan plus prednisone and had rapidly fatal course with organ failure. Hence, we evaluate its availability by reviewing the recent reports of high dose chemotherapy in AL.