해운기업에 있어서 기업내부요인 및 외부환경요인이 전자상거래 활용수준과 성과에 미치는 영향에 관한 실증연구 : 정기선해운영업을 중심으로

조경우(Kyung-Woo Cho) 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.1 No.-

본 연구는 정기선해운영업을 중심으로 해운산업에서의 전자상거래 활용 및 성과에 영향을 미치는 요인들을 도출한 후, 도출된 영향요인들과 전자상거래 활용수준 및 성과간에 어떠한 인과관계가 있는지를 검증하고자 하였다. 이를 위해 우리나라 해운기업들의 내부환경변수인 해운기업특성과 외부환경변수인 해운환경특성이 전자상거래 활용수준에 어떠한 영향을 미치는지와 우리나라 해운기업들의 전자상거래 활용수준이 전자상거래 활용성과에 어떠한 영향을 미치는지의 2단계 연구모형을 구조방정식모델을 통해 실증분석하였다. The purpose of this study is to suggest logical foundation and points which necessarily for establishing E-commerce of Korean shipping companies' development strategy and activation plan. In order to empirical analysis, two step analyses are adopted. Firstly, this study examines the effects of the shipping company character and the shipping environment character on the usage of E-commerce in the shipping companies. Secondly, this study examines the effects of usage of E-commerce on the performance in shipping companies. In the empirical analysis, research hypotheses are being tested mainly by a structural equation model(SEM).

Norepinephrine 에 의한 Natriuresis 의 특성

조경우(Kyung Woo Cho),김선희(Suhn Hee Kim),김민철(Min Chul Kim),안해선(Hai Sun Ann) 대한신장학회 2001 Kidney Research and Clinical Practice Vol.20 No.5

가토 신장에 nor epinephrine을 투여하여 나타나는 postischemic natriuresis 의 기전을 밝히고자 kallikrein 억제제, adenosine 수용체 흥분제와 길항제로 일측 신장을 전처리 하거나 신장 신경을 제거한 후 norepinephrine의 신장 효과를 비교하였다. Prostaglandin 합성 억제제인 indomethacin과 kallikrein 억제제인 aprotinin은 norepinephrine에 의한 natriuresis에 영향을 미치지 않았다. Adenosine 수용체 흥분제(5`-N-ethylcarboxamidoadenosine, NECA; N6-cyclohexyladenosine, CHA)와 길항제(8- phenyltheophylline) 또한 norepinephrine 투여 후의 natriuresis에 영향을 미치지 않았다. 양측 신장 신경을 제거한 가토에서는 norepinephrine 의 postischemic natriuresis 는 나타나지 않았으며 norepinephrine의 신장 억제 효과는 강화되었다. 이상의 결과로 대량의 norepinephrine을 단기간 투여하여 나타나는 소위 postischemic natriuresis 는 prostaglandin 또는 kallikrein 등과의 관련보다는 신장 신경의 역할이 관련되어 있을 것으로 추측하였다. Intrarenal arterial infusion of norepinephrine (NE)or renal arterial occlusion has been reported to cause acute renal failure. However , the pathophysiologicalmechanism inv olved is still not clearly defined. Recently, NE- induced natriuresis localized in the NEinfusedkidney has been found. In the present study,to elucidate the mechanism involved in the NEinduced natriuresis, NE(1.65 μg/ kg/min ) was infusedinto the left renal artery of r abbits and modulation e effect by aprotinin, indomethacin, adenosinereceptor modulator s and bilateral denervation was ex amined. T reatment with aprotinin or indomethacinaffected no changes in NE- induced natriuresis . Also in r abbit s treated with adenosine receptor modulators, no change in NE- induced natriuresis was observed. However, in r abbits bilaterally renal nervedenervated, NE- induced natriuresis was not observed. From these result s, it is suggested that the NEinduced natriuresis is related to an impairment of the renal nerve activity .

논문 : 정기선 해운영업의 거래특성요인이 e-Biz 구현에 미치는 영향에 관한 실증연구

조경우 ( Kyung Woo Cho ) 한국해운물류학회 (구 한국해운학회) 2006 해운물류연구 Vol.49 No.-

자라 신장기능에 미치는 Atrial Natriuretic Peptide의 효과

조경우,김선희,고규영,설경환,Cho, Kyung-Woo,Kim, Suhn-Hee,Koh, Gou-Young,Seul, Kyung-Hwan 대한생리학회 1987 대한생리학회지 Vol.21 No.1

Effects of synthetic atrial natriuretic peptide and furosemide on the cardiovascular and renal functions were examined in the freshwater turtle, Amyda japonica. Both atria and ventricle of turtle contained an immunoreactive atrial natriuretic peptide. Synthetic rat atrial natriuretic peptide (atriopeptin III) and turtle atrial extract caused a decrease in mean arterial blood pressure and the vasodepressor effect was dose-dependent. In hydrated turtles received either atriopeptin III or turtle atrial extract, no significant change in renal function was observed until 100 min except a slight natriuresis at 60 or 100 min after injection of 30 ug/kg atriopeptin III or atrial extract, respectively. However, furosemide, 2 mg/kg, caused marked diuresis, natriuresis and kaliuresis. In non-hydrated turtles, no significant change in renal function was observed until 6 hrs following injection of 30 ug/kg atriopeptin III. Plasma aldosterone decreased at 2 hr and increased at 24 hr after injection of atriopeptin III although plasma renin concentration did not change. But, furosemide caused persistent diuresis, natriuresis and kaliuresis. Additionally, plasma aldosterone and renin concentrations were significantly increased at 24 hrs after injection of furosemide. In conclusion, we suggest that the freshwater turtle may have an atrial natriuretic peptide in heart and vascular receptors for atrial natriuretic peptide, and that atrial natriuretic peptide is more important in the regulation of blood pressure rather than that of renal function in freshwater turtles. We also suggest that an increased plasma renin concentration caused by furosemide may not be due to the sodium concentration delivered to macula densa, but due to the dehydration caused by persistent diuresis and natriuresis.

해운기업의 e-비즈니스 활용과 영향요인에 관한 연구

조경우,Cho, Kyung-Woo 한국항해항만학회 2006 한국항해항만학회지 Vol.30 No.8

본 연구의 목적은 해운기업을 대상으로 e-비즈니스 활용의 영향요인과 활용수준간의 인과관계를 분석하는데 있다. 이를 위해 먼저, 신뢰성분석과 타당성분석(요인분석)을 실시하였다. 다음으로, 어떠한 요인이 e-비즈니스 활용에 더 큰 영향을 미치는 지를 구체적으로 분석하기 위해 도출된 9개의 독립변수와 2개 종속변수를 이용하여 다중회귀분석을 수행하였다. 다중회귀분석 결과, 9개의 요인 중에서 실질적으로 e-비즈니스 서비스업무 활용수준에 영향을 미치는 요인은 5개인 것으로, e-비즈니스 실거래업무 활용수준에는 4개의 요인만이 영향을 미치는 것으로 나타났다. The purpose of this study is to examine the effects of the factors on the usage level of e-business in the shipping companies. In order to do empirical analysis, firstly, this study carried out reliability analysis and factor analysis. Secondly, this study examined the effects of the factors on the usage level of e-business in the shipping companies by multiple regression analysis. In conclusion, the analysis result revealed that 5 factors effect on the service business usage's level and 4 factors effect on the real transaction usage's level of e-business.

신성 고혈압 백서 심방의 심방이뇨 호르몬분비 특성

조경우,설경환,김선희,설경미,고규영,Cho, Kyung-Woo,Seul, Kyung-Hwan,Kim, Suhn-Hee,Seul, Kyung-Mee,Koh, Gou-Young 대한생리학회 1990 대한생리학회지 Vol.24 No.2

It has long been suggested that the cardiac atrium is a low pressure volume receptor controlling body fluid volume and blood pressure. Recently, the cardiac atrium has been found to contain a family of powerful peptides. To clarify the relationship between high blood pressure and the biologically active atrial peptides, experiments were done to define the characteristics of atrial natriuretic peptide secretion in the isolated perfused atria of renal hypertensive rats. Higher concentrations of plasma atrial natriuretic peptide and renin activity were observed in the two-kidney, one clip hypertensive rat compared to the normotensive rat. Atrial volume changes in response to pressure elevations were attenuated in hypertensive rats compared to normotensive rats. Incremental response to atrial volume changes in ANP secretion was accentuated in hypertensive rats. These date suggest that the accentuated atrial natriuretic peptide response to volume changes of hypertensive rats may be a physiological or pathphysiological adaptation to the high blood pressure and may be, at least in part, responsible for the elevated levels of plasma atrial natriuretic peptide observed in hypertensive rats.

RENIN 분필(分泌)에 미치는 온도의 영향(影響)

조경우,Cho, Kyung-Woo 대한생리학회 1980 대한생리학회지 Vol.14 No.1

It has been well known that beta-adrenoceptor is responsible for the renin release stimulatory and alpha-adrenoceptor may be inhibitory. It has been observed accidently that alpha-adrenergic agonist can inhibit renin release by just changing the medium temperature in Vitro experiment in this laboratory. A series of experiments were performed to clarify this interesting phenomena in Vitro experiment. Rat renal slices were incubated in PSS medium under gas phase at $37^{\circ}C$. The following results were observed. 1) Isoproterenol and norepinephrine resulted in renin release stimulatory in dose-dependent by the concentrations of $10^{-9}$ to $10^{-5}\;M/L$ at $37^{\circ}C$. 2) Norepinephrine resulted in renin release inhibitory in dose dependent by the concentrations of $10^{-7}$ to $10^{-5}\;M/L$, and almost no effect by isoproterenol $10^{-6}\;M/L$ at $20^{\circ}C$. 3) Phenoxybenzamine pretreatment at $37^{\circ}C$ accentuated isoproterenol stimulatory effect at $37^{\circ}C$. 4) Phenoxybenzamine pretreatment at $20^{\circ}C$ attenuated isoproterenol stimulatory effect at $37^{\circ}C$. These data suggest that the renal adrenoceptor(s) related to renin release maybe a single entity, and can be interconverted different forms in certain conditions.

신성 고혈압 백서에서 Atrial Natriuretic Peptide의 신장기능에 미치는 효과

조경우,김선희,소준노,류훈,설경환,Cho, Kyung-Woo,Kim, Suhn-Hee,So, June-No,Ryu, Hoon,Seul, Kyung-Hwan 대한생리학회 1989 대한생리학회지 Vol.23 No.1

Since the atrial receptor was suggested to be involved in the control of extracellular fluid volume, it has been shown that the granularity of atrial cardiocytes can be changed by water and salt depletion, and that an extract of atrial tissue, when injected intravenously into anesthetized rats, causes a large and rapid increase in renal excretions of sodium and water. The immunoreactive atrial natriuretic peptide (ANP) has been found in the plasma of patients suffering from various cardiovascular diseases. A high level of ANP in the plasma has been reported in essential hypertension. Several studies on the effects of ANP on renal function and arterial blood pressure have presented contradictory results showing attenuated or accentuated responses. Thus, involvement of the ANP in the development of hypertension remains unresolved. Present study was undertaken to investigate whether the ANP is involved in the development of hypertension in two-kidney one-clip Goldblatt hypertensive rats. The plasma concentration of immunoreactive ANP appeared to be significantly elevated in hypertensive rats as compared with normotensive Goldblatt operated and sham-operated rats. Plasma renin concentration was higher in hypertensive rats than in normotensive rats, as observed in earlier experiments. Intravenous infusions of ANP resulted in increases of urine flow and urinary excretions of sodium and potassium in both hypertensive and normotensive rats. The renal response to ANP was markedly accentuated in Goldblatt hypertensive rats. The plasma concentration of ANP showed a linear relationship with the arterial blood pressure. Infusions of ANP reduced blood pressure both in hypertensive and normotensive rats. These results suggest that in Goldblatt hypertensive rats an elevation of ANP level in the plasma may not be a cause, but instead a consequence of hypertension, and that the renal responsiveness to the ANP is accentuated by some unknown mechanisms.

Changes in Cardiovascular and Renal Functions by Temperature and Epinephrine in the Freshwater Turtle, Amyda Japonica

김선희,조경우,설경환,고규영,Kim, Suhn-Hee,Cho, Kyung-Woo,Seul, Kyung-Hwan,Koh, Gou-Young The Korean Physiological Society 1987 대한생리학회지 Vol.21 No.2

수온변화에 따른 심맥관계 및 신장기능의 변화와 생체실험을 통한 온도에 의한 adrenoceptor의 변형을 알아보기 위해, 무마취 자라에서 $18^{\circ}C$에서 $25^{\circ}C$로 수온을 증가시 나타나는 혈압, 심박동수 및 신장기능의 변화를 관찰하고, epinephrine 1 ug/kg과 10 ug/kg을 상이한 온도에 노출된 자라의 정맥내 투여하여 나타나는 효과를 비교하였다. 1) $18^{\circ}C$에서 $25^{\circ}C$로 수온을 증가시킴에 따라 심박동수는 현저히 증가하여 일정하게 유지되었으나, 혈압 및 혈장 renin 활성도는 변화하지 않았다. 온도증가에 의해 뇨량, 사구체여과율 및 전해질 배설량의 현저한 증가를 보였으나 90분부터는 서서히 감소하기 시작하였다. 2) 수온 $18^{\circ}C$에 노출된 자라에서 epinephrine은 dose-dependent한 양상으로 혈압 및 심박동수를 증가시켰으며, 다량의 epinephrine 투여시 작용시간은 현저히 연장되어 있었다. $25^{\circ}C$에 노출된 자라에서는 epinephrine에 의한 혈압상승 효과 및 심박동수 증가는 나타났으나, dose dependency나 작용시간의 차이는 발견할 수 없었다. 3) 동량의 epinephrine에 의한 혈압 및 심박동수의 증가효과는 $18^{\circ}C$와 $25^{\circ}C$에 노출된 자라에서 유의한 차이를 발견할 수 없었으나, $18^{\circ}C$에 노출된 자라에서 epinephrine의 작용시간 및 반감기가 현저히 연장되어 있었다. 4) Epinephrine 투여에 의해 뇨량, 사구체여과율 및 전해질 배설량의 증가를 관찰하였으며, 이는 dose-dependent 양상이었다. 그러나, 신장효과의 유의한 차이는 상이한 온도에 노출된 두 군에서 발견할 수 없었다. 이상의 결과로, 온도증가에 의한 이뇨 및 sodium 배설효과는 혈관이완에 의한 사구체여과율의 증가에 기인한 것으로 사료되며, 상이한 온도에 노출된 자라에서 epinephrine 효과의 차이를 발견할 수 없었던 것은 본 실험에서 가한 좁은 범위의 온도의 변화 내에서는 adrenoceptor의 변형이 나타나지 않을 것이라고 추론하였다. 그러나 저온에서의 epinephrine의 작용시간의 연장은 아마도 epinephrine의 파괴 효소의 활성도의 감소인 것으로 사료된다.

가토 신장기능에 미치는 Pro-Atrial Natriuretic Peptide의 영향

이정은,조경우,김선희,Lee, Jeong-Eun,Cho, Kyung-Woo,Kim, Suhn-Hee 대한생리학회 1990 대한생리학회지 Vol.24 No.1

It is well known that the atrial natriuretic peptide (ANP) has a prepro-hormone of 151 amino-acids which loses their hydrophobic signal peptide to form 126 amino acid prohormone. The whole prohormone is released and then cleaved by proteases into more than one circulating forms. Recently, Winters et al. (1988a, b) reported that high concentrations of N-terminal fragments of prepro-ANP $(26{\sim}55),\;(56{\sim}92)\;and\;(104{\sim}123)$ were detected in human plasma. However, their physiological roles have not been established. The present study was conducted to determine whether the N-terminal fragments of pro-ANP have any effect on the renal function and to compare the effect with those of G-terminal fragments of pro-ANP The results indicate that intrarenal arterial infusions of prepro-ANP $(26{\sim}41),\;(26{\sim}55),\;(56{\sim}92)\;and\;(104{\sim}123)$ induced no significant changes in renal function. Whereas ${\alpha}-human$ ANP $(prepro-ANP,\;124{\sim}151)$ and pro-ANP caused a significant increase in urine volume, renal plasma flow, glomerular filtration rate, urinary excretions of sodium, chloride and potassium, and fractional excretion of sodium. These results suggest that the N-terminal fragments of pro-ANP are ineffective, while the C-terminal fragments retain the natriuretic and diuretic activities.