녹내장의 신경 보호 치료에 대한 동서의학적 고찰

정혜진,고우신,윤화정,Jung, Hye-Jin,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.3

Objectives : The aim of this study is to understand neuroprotection therapy of glaucoma with both Korean and western medicine.Methods : We searched Pubmed on the title "glaucoma" and "neuroprotection" and also searched CNKI(China National Knowledge Infrastructure) and OASIS(Oriental Medicine Advanced Searching Integrated System) on the title "glaucoma".Results : The results are as follows. 1. In western medicine, excitotoxicity inhibition, immunomodulation, oxidative stress suppression, supplement of NTFs and stem cell therapy are studied with neuroprotection therapy of glaucoma. 2. Treatment of glaucoma in TCM and Korean medicine are associated with liver(肝) and kidney(腎).Conclusions : Korean medical approaches on neuroprotection therapy of glaucoma can be significant, and further studies are needed to research.

콜린성 두드러기에 대한 현대 의학적 연구와 한의학적 고찰

정혜진,고우신,윤화정,Jung, Hye-Jin,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2015 한방안이비인후피부과학회지 Vol.28 No.4

Objects : The aim of this study is to introduce latest research trend of cholinergic urticaria and consider results in view of Korean medicine.Methods : We investigate research papers, Chinese and Korean medicinal papers about Cholinergic Urticaria through Pubmed, CNKI(China National Knowledge Infrastructure) and OASIS(Oriental Medicine Advanced Searching Integrated System).Results : The pathogenesis of cholinergic urticaria is supposed to correlate with sweating, considering that many cholinergic urticaria patients are complicated with anhidrosis or hypohidrosis and have sweat hypersensitivity. And on the basis of those outcomes, diverse therapies on cholinergic urticaria are conducted recently.Conclusion : Korean medicinal approaches and treatment on cholinergic urticaria can be significant, accounting that sweating plays a important role in pathogenesis of cholinergic urticaria.

상추와 원유에서 분리한 황색 포도상구균의 유전형 및 표현형 특징

정혜진,조준일,박성희,하상도,이규호,김철호,송은섭,정덕화,김민곤,김광엽,김근성,Jung, Hye-Jin,Cho, Joon-Il,Park, Sung-Hee,Ha, Sang-Do,Lee, Kyu-Ho,Kim, Cheol-Ho,Song, Eun-Seop,Chung, Duck-Hwa,Kim, Min-Gon,Kim, Kwang-Yup,Kim, Keun-Sung 한국식품과학회 2005 한국식품과학회지 Vol.37 No.1

S. aureus는 자연계에 널리 상재해 있으며 우리나라의 경우 Salmonella spp.에 의한 식중독 다음으로 많이 발생하는 식중독의 원인균으로 알려져 있다. 따라서 본 실험에서는 상추와 원유로부터 분리한 S. aureus(n=86)의 표현형 및 유전형 특징을 파악할 목적으로 coagulase, hemolysin, enterotoxin 및 toxic shock syndrome toxin I 등에 대한 유전자를 대상으로 PCR 방생제 감수성 시험을 수행하여 그들 분리균주들의 항생제 내성정도를 결정하였다. 상추와 원유로부터 분리한 S. aureus 균주는 모두 coagulase 유전자를 보유하고 있었고, 또한 PCR 산물의 amplicon size는 500bp(2.4%), 580bp(17.4%), 660bp(61.6%), 740bp(17.4%) 및 820bp(1.2%)로 다섯 종류가 검출되었다. Hemolysin 유전자의 경우는 원유로부터 분리한 4개의 hld 유전자 보유균주를 제외하고 모든 분리균주에서 multiple hemolysin gene을 보유하였으며, 그 중 47개 균주(54.7%)가 hla/hld/hlg2 유전자를 모두 소유한 균주로서 가장 많은 분포를 나타내었다. 한편, enterotoxin 유전자를 소유한 S. aureus 분리균주는 37 균주(43.0%)로서 그중 32균주(37.2%)에서 sea 유전자가 검출되었고, 1균주(1.1%)에서 sed 유전자, 그리고 4균주(4.6%)에서 sea와 sed 유전자가 모두 검출되었으나, seb, sec 혹은 tsst-1 유전자는 검출되자 않았다. 그리고 항생제 감수성 시험 결과에서는 모든 균주가 ciprofloxacin, oxacillin, vancomycin 그리고 trimethoprim/sulfamethoxazole에 대하여 감수성을 나타내었고 penicillin G(98.8%)는 높은 감수성을 보였으나 chloramphenicol(63%)과 erythromycin(59%)은 감수성이 낮았고, chloramphenicol, clindamycin, erythromycin 및 penicillin G에 대하여는 각각 4.7%, 82.6%, 14.0% 및 1.2%의 균주가 내성을 가지고 있었다. 또한 항생제 다제내성 양상을 살펴본 결과에 의하면 사용된 8종류의 항생물질들 중 2가지 항생물질에 대하여 내성을 나타낸 균주는 7개(8.1%)이고, 3종 이상의 항생물질에 대하여 다제 내성을 보이는 균주는 나타나지 않았다. To characterize genotypic and phenotypic traits of Staphylococcus aureus isolates (n = 86) from lettuces and raw milk, major virulence-associated genes and antibiotic susceptibility were detected using PCR-based methods and disk diffusion method, respectively. All isolates possessed coagulase gene and showed five polymorphism types [500 bp (2.4%), 580 bp (17.4%), 660 bp (61.6%), 740 bp (17.4%), and 820 bp (1.2%)] due to variable numbers of tandem repeats present within the gene. Two or three different loci of hemolysin gene family were dominant in isolates, 47 of which (55%) possessed combination of hla/hld/hlg-2 genes as the most prevalent types. Among enterotoxin-encoding genes, sea was detected from 32 isolates (37%), sed from 1 isolate (1%), and sea and sed genes were co-detected from 4 isolates (5%), whereas seb, sec, and tsst-1 genes were not detected. All isolates were susceptible to ciprofloxacin, trimethoprim/sulfamethoxazole, oxacillin, and vancomycin, 85 isolates (99%) to penicillin G, 54 isolates (63%) to chloramphenicol, 51 isolates (59%) to erythromycin, and 7 isolates (8%) to clindamycin. Among resistant isolates, seven displayed multiantibiotic-resistance against two different antibiotics.

중환자실 간호사 근무환경과 환자가족 만족도의 관계

정혜진,강지연,Jung, Hye-Jin,Kang, Jiyeon 한국중환자간호학회 2014 중환자간호학회지 Vol.7 No.2

Purpose: The purpose of this study was to investigate the nursing work environment and family satisfaction in Korean intensive care units (ICUs). Methods: The study participants were 190 critical care nurses and 133 family members of ICU patients who were randomly chosen from four of the hospitals located in B city. The Korean Nursing Work Environment Scale was used to assess the work environment of critical care nurses. Family satisfaction was measured with the Korean version of the Critical Care Family Needs Inventory. Results: Critical care nurses reported moderate satisfaction with their work environment. The mean score for family satisfaction was 3.59 on a 5-point scale, and satisfaction with information provision received the highest score. Family satisfaction was higher in hospitals where the critical care nurses evaluated their work environment positively. Conclusion: This study revealed that the work environment of nurses affects family satisfaction in ICUs. Therefore, it is necessary to explore various methods of improving the critical care nursing work environment in order to provide the highest possible level of nursing care.

핵융합 재료 조사 손상에 관한 다단계 전산모사의 연구 동향

정혜진 ( Hye Jin Jung ),이승철 ( Seung Cheol Lee ),최정혜 ( Jung Hae Choi ),오상준 ( Sang Jun Oh ) 대한금속재료학회 2008 재료마당 Vol.21 No.2

고정층 가스화에 의한 나왕톱밥으로부터 수소제조특성

정혜진 ( Hye Jin Jung ),김철호 ( Chul Ho Kim ),손재익 ( Jae Ek Son ),김래현 ( Lae Hyun Kim ),신헌용 ( Hun Yong Shin ) 한국공업화학회 2008 공업화학 Vol.19 No.2

특별계획구역 용적률 인센티브에 의한 부동산 개발사업의 비용편익 조정효과 연구

정혜진(Jung, Hye Jin),서충원(Suh, Chung Won) 한국부동산학회 2009 不動産學報 Vol.37 No.-

1. CONTENTS (1) RESEARCH OBJECTIVES As the focus of this study, the "Special Districts" in Seoul, which were designated and made by public in the early 2000s, are in a close relation to the balance between public benefit and private benefit. The objective of this research is to evaluate effectiveness of incentive zoning in the special planning districts. (2) RESEARCH METHOD This research conducted cost-benefit analysis focused on the benefit-cost ratio(BCR) of private sector. (3) RESEARCH FINDINGS The result of this study is as follows. According to analysis, the monetary value assessment of these factors showed that BCR of the private sector measured in the case sites was 1.95 on average, and major costs in the private sector were cost of land and cost of construction, while benefits were sales of buildings. The ratio of incentive is 29% and the ratio of additional building area is 1,42 in detail. Therfore in a view point of total amount, the effectiveness of incentive zoning is reasonal, but internal influencing factors say that current incentive system is unbalance between private benefit and public benefit. Because private cost, for example, cost of land and cost of construction, would give back indirect benefit in the process of development under the current incentive system. 2. RESULTS The study says that the standard for the judgment on the balance between public benefit and private benefit should be a practical exchange of value, not the current exchange of area relying on a calculation equation.

‘仁內義外 논쟁’에 나타난 맹자의 性의 개념 : 메타프락시스적 관점

정혜진(Hye-Jin Jung) 한국도덕교육학회 2018 道德敎育硏究 Vol.30 No.1

맹자와 고자 사이에 벌어진 ‘仁內義外 논쟁’은 표면상 仁義가 안인가 밖인가 하는 문제에 대한 두 사람사이의 의견대립을 보여주고 있지만, 그 이면에는 사단과 사덕의 개념 더 나아가 性의 개념에 관한 두 사람사이의 견해가 밑바탕에 깔려 있다. 본 논문에서는 맹자와 고자사이에 벌어진 인내의외 논쟁의 요지를 밝히고 사단과 사덕의 개념과 관련하여 논쟁의 의의를 해석하였다. 이 과정에서 드러나는 맹자의 性의 개념은 그것은 四德―仁義禮智―과 일관된 방향의 실천에 의하여 확립되는 것이라는 점, 그리고 이러한 실천에 의하여 확립된 마음 그것이 바로 ‘四端으로서의 性’이라는 ‘순환론적 사고’를 보여준다. 맹자는, ‘인의예지’라는 ‘삶의 이상적 표준’을 향해서 나아가도록 세팅되어 있는 인간의 性을 도외시하고, ‘식색으로서의 성’만을 인간의 性으로 간주하는 고자의 성론을 받아들이기 어려웠을 것이다. 그러나 「맹자」에는 ‘식색으로서의 성’을 충족시키는 활동을 하는 동안에 내내 그것을 통하여 ‘사단으로서의 性’을 실현시켜야 한다는 점이 누차 강조되고 있으며, 이점이 바로 맹자의 性의 개념은 메타프락시스적 관점을 예시한다고 볼 수 있는 근거이다. The purpose of this paper is to interpret the so-called debate between Kaozi(告子) and Mengzi(孟子) concerning on Jen Nei Yi Wai(仁內義外) from the perspective of Metapraxis. The Mencius’ s the concept of Hisng(性) in the process of this interpretation is to reveal clearly. According to this study, Mencius seeks the following: Hisng(性) is established by the practical effort forward Jen Yi Li Chih(仁義禮智) that is the ideal standards of human life. Also, human nature was designed to proceed for the ideal standards of human life. This shows cyclical thinking in that being innate is confirmed by none other than the practical effort forward Jen Yi Li Chih(仁義禮智). And to conclude, we are bound to pursue the divine nature in our activities that meet our instinctive desires. That is why Mencius’ s the theory of Hisng(性) is seen as an example of metapractical views.

도시 내 친보행공간의 통합적 계획을 위한 그린웨이 유형 연구

정혜진(Jung Hye-Jin),최지영(Choi Ji-Young),양석우(Yang Suk-Woo) 대한건축학회 2007 대한건축학회논문집 Vol.23 No.10

The object of this research is to know original meanings of greenway planning which was recently introduced to Korea, and to introduce foreign greenway planning cases which have been evolved into integrative planning term. Especially, by analyzing cases of foreign greenway planning, we deduced several types of greenway which could be adoptable to us and help us planning and designing greenway network in Korea. The result of this research is greenway cases of New York, Boston, and Singapore have more multiple objectives than ones in korea which have only single objective such as ecological corridors or bike ways. In the beginning, they planed greenway as a passive term such as parks and open spaces, ecological corridors and bike ways. but they understood that greenway became more valuable when greenway was planned as a part of one integrative network. Therefore greenway is being planed as a part of integrative network which includes all linear facilities in city. And also, from studying foreign theories about greenway, we can set up the standards of classification which are its objective and function, existing land use, and planning form. and According to mutual relation of these standards, we finally deduce 13 types of greenway.

칸트와 불교 : 선험적 인식론과 수행적 인식론

정혜진(Hye-Jin Jung) 한국도덕교육학회 2017 道德敎育硏究 Vol.29 No.2

칸트는 논리적 분석을 통하여 ‘이념’이 인간의 인식에서 어떤 역할을 하는가 하는 점을 분명히 밝힘으로써, 이념이 인식의 ‘논리적 가정’임을 드러내었다. 그러나 칸트의 선험적 인식론은 ‘이념’이라는 형이상학적 실재를 ‘마음’으로 규정함으로써 그 기반을 확고히 하였지만, 이념이 삶과 관련하여 어떤 의미를 지니는가 하는 점을 제대로 드러내지 못하였다는 점에서 한계를 지닌다. 만약 삶과 관련하여 칸트의 ‘이념’의 의미를 드러낸 이론을 찾는다면 그것은 필경 불교의 수행이론일 것이다. 불교수행이론에서 ‘진여’(眞如)는 수행의 과정, 즉 삶의 과정 속에서 ‘삶의 표준’으로 작동한다. ‘진여’는 칸트철학에서의 ‘이념’에 해당하는 용어이며, 기신론은 이 진여가 인식과 수행에 어떻게 관여하는가를 보여준다. 기신론은 인식의 과정을 수행의 과정과 동일한 과정으로 보고 그 사이의 개념적 관련을 ‘순환론적으로’ 설명한다는 점에서, 칸트의 선험적 인식론과 차별화되는 인식론, 이른바 ‘수행적 인식론’을 보여준다. 기신론의 수행적 인식론은 메타프락시스적 사고방식의 전형을 예시한다. Kant reveals the ‘logical presupposition’ of human cognition by clarifying how ‘Idea’ works at human’s recognition through logical analysis. In other words, the transcendental epistemology of Kant acquires the metaphysical reality known as ‘Idea’ from mind and establishes it, but it has limitation in that it failed to reveal what meaning does Idea possesses in regard to our life. If we look for a theory that reveals the meaning of Kant’s ‘Idea’ in regard to our life, it will be the theory of Buddhist practice in the end. The theory of Buddhist practice explains ‘Suchness’(眞如) in terms of the process of life, that is, the practice of our life. The term that matches Kant’s ‘Idea’ in this theory is ‘Suchness’, and the theory starts from the assumption that this ‘Suchness’ exists from beginning. The explanation of the theory shows the practical epistemology, which is differentiated from Kant’s transcendental epistemology, in that it explains the significance of ‘Suchness’ ‘practically’ through the process of cultivation of mind, not only to mention the process of human cognition. The practical epistemology of Buddist indicates the archetype of Metapractical epistemology.