핀랜드의 산업보건체계

이원진,Lee, Won-Jin 대한산업보건협회 1990 산업보건 Vol.28 No.-

환경보건에서의 주민 참여

이원진,Lee, Won-Jin 한국환경보건학회 2011 한국환경보건학회지 Vol.37 No.5

모 사업장 포장부서 근로자들에서 발생한 수근터널증후군에 대한 조사연구

이원진,이은일,차철환,Lee, Won-Jin,Lee, Eun-Il,Cha, Chul-Whan 대한예방의학회 1992 예방의학회지 Vol.25 No.1

반복작업에 종사하는 모 사업장 포장부서 근로자 42명을 대상으로 수근터널증후군에 대한 중상, 이학적 검사 및 근전도 검사를 1991년 11월부터 1992년 3월까지 실시하였다. 양손 모두에서 근전도상 이상소견을 보인 경우가 4명, 오른쪽 손에만 이상소견을 보인 경우가 4명 그리고 왼손이 1명 등 총 9명으로서 21.4%의 높은 유병률을 나타내었다. 임상중상은 전체 42명중 66.7%에 해당되는 28명에서 나타났다. Tinel과 Phalen sign 등 이학적 검사에서 이상소견을 보인 경우는 14명으로 전체의 33.3%를 차지하였다. 그리고 키와 임신 횟수를 제외한 수근터널증후군에 대한 다른 일반적 위험요인은 환자군과 비환자군에서 유의한 차이는 없었다. 근전도 검사를 기준으로 하였을 때 임상증상에 대한 민감도는 0.89, 특이도는 0.39이었고 Tinel sign에서는 각각 0.33, 0.88 그리고 Phalen sign에서는 0.56, 0.82 등이었다. 임상증상이 있고 Tinel과 Phalen sign에서 어느 하나 양성으로 나타나는 것을 선별기준으로 하였을 경우의 민감도와 특이도는 0.57, 0.76이었다. The carpal tunnel syndrome is one of the most common peripheral nerve entrapment syndromes. The typical symptoms are pain, numbness and paresthesia in the median nerve territory of the hand. Recently, it is widely recognized that occupational factor is regarded as the important cause of the carpal tunnel syndrome. Clinical study is performed in the 42 female workers who is repetitively working at packing department in a rayon manufacturing factory from November 1991 till March 1992. The study included a questionnaire, physical examinations, and the neurophysiological test. The summary of the results obtained was as follows : 1. Among 42 packing workers, 9 workers(21.4%) were diagnosed as carpal tunnel syndrome by electromyography. The affected side was bilateral in 4 workers(9.5%), right in 4 workers(9.5%), and left in one worker(2.4%). 2. Among 42 subjects, 28 workers(66.7%) complained the clinical symptoms related to carpal tunnel syndrome, 11 workers(26.2%) showed positive Phalen sign, and 7 workers(16.7%) showed positive Tinel sign. 3. Researchers regard electromyographic finding as the gold standard for diagnosis of carpal tunnel syndrome. The sensitivity and specificity of the clinical symptoms to diagnose the carpal tunnel syndrome were 0.89, 0.39 respectively. If the carpal tunnel syndrome is diagnosed by the combination of the positive findings of the symptoms and the physical examinations, either Tinel or Phalen sign, the sensitivity and specificity were 0.67 and 0.76 respectively. Considering above results, though this small number of workers is not adequate for epidemiologic conclusions, carpal tunnel syndrome seems to be an important occupational disorder among packing workers in a rayon manufacturing factory.

연 폭로 근로자들의 지질과산화 및 항산화상태에 관한 연구

이원진,황천현,김청식,장성훈,김양호,김해준,Lee, Won-Jin,Hwang, Cheon-Hyun,Kim, Cheong-Sik,Chang, Soung-Hoon,Kim, Yang-Ho,Kim, Hae-Joon 대한예방의학회 1998 Journal of Preventive Medicine and Public Health Vol.31 No.3

This study was started to find out if plasma malondialdehyde(MDA), $\alpha-tocopherol$ and erythrocyte superoxide dismutase(SOD) activity could be markers of biological activity resulting from exposed to lead in workers. Blood samples were randomly obtained from lead-exposed workers(n=29), $CO_2$, welders(n=60) and office workers(n=60). We used whole blood to analyse blood lead with atomic absorption spectrophotometer. Superoxide dismutase activity in erythrocyte was measured with spetrophotometer. MDA and $\alpha-tocopherol$ in plasma were measured with high performance liquid chromatography. Lead-exposed workers was significantly high in blood lead concentration$(29.37{\mu}g/d\ell)$ compared with welders$(6.42{\mu}g/d\ell)$ and office workers$(5.01{\mu}g/d\ell)$. The level of plasma MDA was significantly higher in the lead-exposed workers($1.87{\mu}mol/g$ cholesterol) than the welders($1.41{\mu}mol/g$ cholesterol) and office workers($1.41{\mu}mol/g$ cholesterol). Erythrocyte SOD activity in lead-exposed workers(56.80 U/g Hb) was significantly increased than those of welders(37.63 U/g Hb) and office workers(20.47 U/g Hb). The plasma $\alpha-tocopherol$ level of lead-exposed workers($4.93{\mu}g/g$ cholesterol) was statistically different from welders($4.25{\mu}g/g$ cholesterol) and office workers$4.28{\mu}g/g$ cholesterol). Neither age nor smoking was related to SOD or MDA level. Blood lead was significantly correlated with erythrocyte SOD activity(r=0.405), plasma MDA(r=0.296) and $\alpha-tocopherol$ (r=0.207). Plasma MDA was also significantly correlated with SOD (r=0.217). In multiple regression analysis, the change of MDA and SOD activity level related to the blood lead concentration. These results suggested that the increase of plasma MDA and erythrocyte SOD activity in lead-exposed workers had a close relationship with the oxidative stress induced by lead.

동독의 산업보건 체계

이원진,Lee, Won-Jin 대한산업보건협회 1990 산업보건 Vol.29 No.-

미래를 위한 과거의 교훈

이원진,Lee, Won-Jin 한국환경보건학회 2011 한국환경보건학회지 Vol.37 No.3

허혈 재관류 손상 실험의 쥐 생체 모델 작성

이원진,박희철,홍기우,Lee, Won-Jin,Park, Hui-Cheol,Hong, Gi-U 대한흉부심장혈관외과학회 1995 Journal of Chest Surgery (J Chest Surg) Vol.28 No.11

Ischemia reperfusion injury occurs in various diseases. The role of oxygen free radicals in IR injury of the lung has been spotlighted and many studies have been performed. In this study, we tried to prepare a stable rat lung model for IR injury, focusing on surrounding conditions as hilar stripped left lung, clamped left pulmonary artery and bronchus,and declamped after determined period was passed, and right main pulmonary aretery was clamped. Arterial blood gas analyes were performed at 1, 10, 20, 30, minutes after reperfusion. Before clamping, PaO2 was 95 to 120 mmHg in all animals. There were six groups; Group I : temperature 15o C, and 120 minutes clamping, Group II: 20 oC, and 120 minutes clamping, Group III : 25 oC, and 120 minutes clamping, Group IV : 15oC, 90 minutes clamping, Group V : 20 oC, 90 minutes clamping,Group VI: 20 oC, 75 minutes clamping. Each groups contained 10 Sprague Dayley rats. The humidity was maintained 100 % as circulation imerged isotonic Hartmann`s solution of the pleural cavity. In group IV, V, and VI, PaO2 decreased significantly in all animals immediately after reperfusion, but 43 % survived till 10 minutes after reperfusion, it was 74.0$\pm$5.7, 73.3$\pm$10.8,and 88.2$\pm$17.7 mmHg. Pulmonary edema was observed histologically in 2/10 animals in group IV, 6/10 in group V , 3/10 in group VI, 9/10 in group I, and the other lungs showed all edema. We established a stable model by setting ischemic time,and temperature, between 75 to 90 minutes,15 to 20o C, and isotemperature Hartmann`s solution immersion of the pleural cavity.

1 wt% Y₂O₃ 첨가계 AlN 세라믹스의 소결 조건에 따른 전기전도도

이원진,이성민,심광보,김형태,Lee, Won-Jin,Lee, Sung-Min,Shim, Kwang-Bo,Kim, Hyung-Tae 한국세라믹학회 2007 한국세라믹학회지 Vol.44 No.2

Electrical properties of AlN ceramics sintered with 1 wt% $Y_2O_3$ have been investigated. From the impedance spectroscopy, electrical conductivity of grain boundary was found to be much lower than that of grain. DC conductivity measurement showed the electrode polarization effects caused by blocking electrode. The heat-treatment at $1700^{\circ}C$ of the specimen sintered at $1850^{\circ}C$ transformed continuous pain boundary phases along triple boundary junctions into isolated particles in grain comers. The heat-treatment induced decreases both in grain and grain boundary conductivity, and in DC electrical conductivities. From the analysis on the transference number, ionic conductivity was shown to be more dominant than electron conductivity, which was due to ion compensation mechanism during oxygen incorporation into grain.

서독의 산업보건 체계

이원진,Lee, Won-Jin 대한산업보건협회 1990 산업보건 Vol.30 No.-

Erythrocyte Cholinesterase Activity and Demographic Factors in Healthy Human

이원진,김청식,김진석,장성훈,Lee, Won-Jin,Kim, Cheong-Sik,Kim, Jin-Seok,Chang, Soung-Hoon 한국농촌의학.지역보건학회 2000 농촌의학·지역보건 Vol.25 No.1

적혈구 콜린에스테라제 활성도와 성, 연령, 키, 몸무게, 음주 및 흡연력 등 인구학적 특성과의 관련성을 살펴보기 위해서, 두 곳의 농약 사업장 근로자 52명과 의과대학생 51명 등 총 103명을 대상으로 현장 검사용 기계를 이용해 2000년 1월부터 2월까지 적혈구 콜린에스테라제 활성도를 측정하였다. 조사 대상자는 남성이 89명(86.4%), 여성이 14명(13.6%)였으며 평균 연령은 각각 $31.8{\pm}11.4$, $27.1{\pm}10.1$ 세였다. 측정된 적혈구 콜리에스테라제 활성도의 평균값은 남성에서 $34.7{\pm}3.9$ U/g hemoglobin, 여성에서 $34.0{\pm}4.0$ U/g hemoglobin으로 군간 유의한 차이가 없었다. 한편 적혈구 콜린에스테라제 활성도와 조사된 모든 인구학적 변수들간에는 유의하지 않은 매우 낮은 상관성만이 관찰되었다. 결론적으로 적혈구 콜린에스테라제 활성도는 혈장 콜린에스테라제 활성도와는 달리 성, 연령, 키, 몸무게 등 인구학적 변수와 상관성을 보이지 않는다고 판단되었다.