각막 간질내 공기 주입과 평형염액 주입이 간질세포 자멸사에 미치는 영향 비교

이민정,이현주,위원량,이진학,김미금,Min Joung Lee,M,D,Hyun Ju Lee,Won Ryang Wee,M,D,Jin Hak Lee,M,D,Mee Kum Kim,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.4

Purpose: To evaluate the effects of intrastromal air injection and intrastromal balanced salt solution (BSS) injection on corneal keratocyte apoptosis. Methods: Twelve right eyes of New Zealand White rabbits were divided into an air-injected group (n=6) and a hydro-injected group (n=6). Contralateral eyes served as a control. Air or Balanced salt solution (BSS?, Alcon, USA) was injected into the deep corneal stroma at the paracentral area to propagate into nearly the entire cornea. To reduce the intraocular pressure, anterior chamber paracentesis was performed. The animals were sacrificed 4 hours (n=6) and 24 hours (n=6) after surgery. Central cornea buttons were retrieved to stain with Hematoxylin & Eosin and TUNEL (Apoptag?, Chemicon). The mean number of apoptotic keratocytes was counted in 24.67±4.04 consecutive high power field (HPF). Results: The mean number of TUNEL-positive cells at 4 hours was 12.85±7.25/HPF and 0.25±0.44/HPF in air-injected and hydro-injected eyes, respectively. It was reduced to 6.25±4.02/HPF and 0.15±0.37/HPF in air-injected and hydro-injected eyes after 24 hours. The air-injected group showed significantly more TUNEL-positive cells compared with the hydro-injected or control group until 24 hours (p=0.001, p=0.001, Mann-Whitney U test). Conclusions: Intrastromal air injection induces significant apoptosis of keratocytes suggesting some damages in the peripheral cornea when used in deep lamellar keratoplasty.

백내장 수술 후 후낭 혼탁의 조기 발생에 영향을 주는 요인

이민정-,이진학,Min Joung Lee-,Jin Hak Lee 대한안과학회 2007 대한안과학회지 Vol.48 No.4

Purpose: To identify factors affecting early development of posterior capsular opacity after cataract surgery. Methods: The medical records of patients who had undergone phacoemulsification and intraocular lens implantation with the same surgeon from January 1997 to May 2003 were reviewed. This study recruited 3625 eyes. Age, sex, systemic diseases, preoperative visual acuity, and intraocular lens materials were compared between the early capsulotomy group (Group 1, where the interval from cataract surgery to capsulotomy ≤6 months, 38 eyes) and the late capsulotomy group (Group 2, where the interval from cataract surgery to capsulotomy ≥3 years, 39 eyes). Results: The mean age for Group 1 was 56.76±15.96 years and that for Group 2 was 61.97±13.46 years (p=0.125, Student t-test). No significant differences were seen between Group 1 and Group 2 with respect to diabetes or hypertension (p=0.166 and p=0.109, Pearson’s chi-square test). There was a significant difference in intraocular lens materials between Group 1 and Group 2 (p=0.002, Pearson`s chi-square test), and significantly fewer eyes with PMMA lenses than with silicone or acrylate lenses in Group 1 (p=0.001 and p=0.005, Pearson`s chi-square test). Conclusions: The number of eyes with PMMA lenses was significantly smaller than the number with silicone or acrylate lenses in the early capsulotomy group. This suggests that PMMA intraocular lenses may induce posterior capsular opacity later in the postoperative period than silicone or acrylate lenses.

단안의 안검하수를 주소로 발견된 다발성 골수종 1예

이민정,정호경,곽상인,양희진.Min-Joung Lee. M.D... Ho-Kyung Choung. M.D... Sang-In Khwarg. M.D... Hee-Jin Yang. M.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.6

Purpose: As orbital involvement in multiple myeloma is rare, the correct diagnosis is usually difficult. We report a case of multiple myeloma which involved the orbit, and which presented with unilateral ptosis. Methods: A 35-year-old man was referred for the evaluation of ptosis of the left eyelid for 1 month. The levator function was normal, and there was no proptosis. Orbital computerized tomography (CT) revealed an orbital mass lesion involving the superior orbital ridge with intracranial extension. Results: Excisional biopsy was performed through craniotomy and superior orbitotomy. Histopathologic examination and immunostaining result suggested a diagnosis of a plasmacytoma. The diagnosis of multiple myeloma was confirmed through bone marrow aspiration and biopsy showing diffuse infiltration of plasma cells. Conclusions: We experienced a case of multiple myeloma, which is rare in the orbit presenting unilateral ptosis. In addition, the possibility of orbital mass should be considered as an unusual cause of unilateral, acquired, progressive ptosis.

거짓비늘증후군에 동반된 단독 섬모체망막동맥폐쇄 1예

이민정,박영걸,안재균,Min Joung Lee,Yeoung Geol Park,Jae Kyoun Ahn 대한안과학회 2006 대한안과학회지 Vol.47 No.10

Purpose: To report a case of isolated cilioretinal artery occlusion associated with pseudoexfoliation syndrome. Methods: A 66-year-old female presented with acute vision loss of the right eye. Three months prior, she had been diagnosed as having pseudoexfoliation glaucoma of both eyes, and the intraocular pressure of both eyes had been well-controlled with topical medication. Results: The presenting visual acuity in her right eye was 20/100. Fundus examinations showed sectoral retinal whitening on superior macula. Fluorescein angiography revealed delayed filling of the cilioretinal artery, consistent with cilioretinal artery occlusion. No significant findings were identified by carotid doppler examination or echocardiography. After 8 weeks, retinal changes were completely resolved with improvement of her right vision to 20/25. Conclusions: Isolated cilioretinal artery occlusion may develop as an intraocular manifestation of pseudoexfoliation syndrome.

아르곤레이저 치료후 재발한 중심와아래 맥락막신생혈관에 대한 광역학치료

이민정,송수정,정흠,유형곤,Min-Joung Lee,M,D,Su-Jeong Song,M,D,Hum Chung,M,D,Hyeong-Gon Yu,M,D 대한안과학회 2005 대한안과학회지 Vol.46 No.12

Purpose: To evaluate the effects of photodynamic therapy for subfoveal recurrences of juxtafoveal or extrafoveal choroidal neovascularization (CNV), previously treated with argon-laser photocoagulation. Methods: Seven eyes, previously treated with argon-laser photocoagulation for juxtafoveal or extrafoveal choroidal neovascularization, received photodynamic therapy for subfoveal recurrence. Changes in visual acuity and fluorescein angiographic findings were analyzed. Results: The average time of appearance of recurrent CNV after laser photocoagulation was 43.14±29.62 months (range, 2-77 months). After photodynamic therapy, fluorescein leakage and neovascular lesion size decreased in all patients on fluorescein angiography. Visual acuity was stabilized or improved in 5 of 7 eyes. Conclusions: Photodynamic therapy was effective in patients with subfoveal recurrences of juxtafoveal or extrafoveal choroidal neovascularization previously treated with argon-laser photocoagulation.

3∼5세 누리과정과 초등 1학년 교육과정에서 언어교육의 연계성 분석

이민정 ( Min Joung Lee ) 미래유아교육학회 2015 미래유아교육학회지 Vol.22 No.2

본 연구의 목적은 3~5세 누리과정과 초등 1~2학년군 교육과정에서 3세부터 초등 1학년까지언어교육의 연계성을 살펴보는 것이다. 분석대상은 3~5세 누리과정의 의사소통영역의 세부내용과 초등 1학년 국어과의 내용성취기준이며, 3세 17개, 4세 25개, 그리고 5세 25개의 세부내용과 초등1학년 국어과 내용성취기준 19개의 연계성을 분석하였다. 연구 분석결과, 연계된 정도는 3세와 4세는 72%, 4세와 5세는 100%, 5세와 초등 1학년은 72%가 연결되었다. 연계형태는 3세와 4세의 경우는 ‘반복’이 8개 항목, ‘발전’이 10개 항목(심화: 6개 항목, 확대·심화: 4개 항목)이었고, 비연계의 경우는 ‘격차’의 ‘생성’에서 총 7개 항목이었다. 4세와 5세의 연계형태는 ‘반복’이 10개 항목, ‘발전’이 15개 항목(확대: 3개 항목, 심화: 11개 항목, 확대·심화: 1개 항목)이었고, 비연계는 없었다. 5세와 초등 1학년의 연계형태는 ‘반복’이 4개 항목, ‘발전’이 14개 항목(확대: 1개 항목, 심화: 7개 항목, 확대·심화: 6개 항목)이었고 비연계는 소멸에서 7개 항목이었으며, 초등 1학년 국어교육과정에서는 9항목이 생성되었다. 즉 3세에서 초등 1학년까지의 언어교육내용의 연계성은 3세와4세, 4세와 5세, 그리고 5세와 초등 1학년으로 올라갈수록 ‘반복’과 ‘발전’의 형태로 연계가 이루어지고, 3세에서 4세, 5세에서 초등학교 1학년은 새로운 내용이 각각 ‘생성’되었으며, 5세에서 초등1학년의 경우에서만 비연계에 해당되는 ‘소멸’이 있었다. The purpose of this study was to investigate the Nuri curriculum for three- to five-year-old children and first and second graders to determine the association in language education, focusing on the contents of language education in early childhood and elementary school education curricula. The criteria for content achievement in the subject of Korean language for the first graders and the details in the area of communication in the Nuri curriculum for three- to five-year-old children were analyzed to determine association between 17 details for three-year-old children, 25 for four-year-old children, and 25 for five-year-old children and 19 criteria for content achievement in the subject of Korean language for the first graders. The association was estimated to be 72% between three- and four-year-old children, 100% between fourand five-year-old children, and 72% between five-year-old children and the first graders. Between three- and four-year-old children, association involved ‘repetition’ in eight items and ‘development’ in ten items (reinforcement in six items and extension and reinforcement in four items) and non-association involved ‘generation’ of ‘gap’ in seven items in total. Between four- and five-year-old children, association involved ‘repetition’ in ten items and ‘development’ in 15 items (extension in three items, reinforcement in eleven items, and extension and reinforcement in one item) and non-association was not found. Between five-year-old children and the first graders, association involved ‘repetition’ in four items and ‘development’ in fourteen items (extension in one item, reinforcement in seven items, and extension and reinforcement in six items); non-association involved extinction in seven items; and nine items were generated in the Korean language curriculum for the first graders. Therefore, association was found in such forms as ‘repetition’ and ‘development’ between three- and four-year-old children, between four- and five-year-old children, and between five-year-old children and first graders; new contents were ‘generated’ between three- and four-year-old children and between five-year-old children and first graders and non-association, ‘extinction,’ was only found between five-year-old children and first graders.

상점가 재생을 둘러싼 갈등상황과 정책과제

이민정(Lee, Min Joung) 한국갈등관리학회 2015 한국갈등관리연구 Vol.2 No.1

본 연구는 일본 도쿄도 나카노부(中延) 상점가 사례를 통해 ‘지역적 상업시스템’의 재편단계에서 보이는 갈등상황을 도출하고, 구성원 간에 벌어지는 갈등상황에 초점을 맞춰 갈등에 대한 대처방법과 이를 통해 얻을 수 있는 정책적 시사점을 도출했다. ‘유상볼런티어’라고 하는 발전가능성이 높은 시스템을 구상한 새로운 타입의 NPO의 등장과, 그 NPO와의 연계가 지역적 상업시스템의 각 단계마다 상인, 상인-상점가조직, 상점가조직-상인-NPO 사이에 일어는 갈등상황에 주목한 사례분석을 시도했다. 초기단계 비즈니스(Early Stage Business)이기에 겪는 미숙함, 미경험을 도와줄 행정정책이 필요하다. 행정섹터의 빈틈을 NPO섹터가 메꾸는 기능을 생각할 때, 두 섹터의 파트너십이 불러올 플러스 효과는 크다. 새로운 사업모델, 형태에 대한 행정의 보다 유연한 대응이 필요하다. 쇠퇴일로에 있는 상점가에 있어, NPO와의 연계는 상점가의 부족한 기능을 보완하고 지역주민의 니즈에 부응하여 공공성을 자연스럽게 가져가면서, 이를 통해 지역 내에서의 중심성을 강화한다. 재정적 자립기반이 취약한 NPO의 초기 단계에 그들의 아이디어에 의존하려는 일방적 수혜의 모습이 아닌, 장기적 · 지속적 연계를 염두에 둔 상생의 모델구축에 대한 고민이 필요하다. This paper aims to explain the conflictual situation over the reorganizing process and between members through the case of Nakanobu shopping-street. The NPO which invented the very new model called "Paid-volunteer" and Nakanobu has connected activities, and this connection caused the various conflicts in the stage of "Local retail system". In order to differ from the earlier studies, the dynamic and institutional perspective and a new theory called "Local retail system" are used for the case analysis. The implications are as below. First, the administrative policy to help the early stage business is needed. The early stage business, especially NPO which has a weak financial foundation, has a little experience and their system are unskilled when it actually starts to operate. In respect the NPOs" function to fill a administrative gap, the partnership between these 2 sectors has an important meaning. Second, the administration and the organization of retail agglomeration should cope with NPOs new models more flexibly. The retail agglomerations have faced on declining situation so they need to complement functions by connecting with different organization, like NPOs. Through connected activities the retail agglomeration can strengthen the local centrality. And it is needed not the dependant relationship but the win-win model for the long-term and sustainable connect.

국내 항공사 승무원의 직무스트레스 요인 척도개발

이민정(Min-Jung Lee),김정만(Joung-Man Kim),이계희(Gyehee Lee) 한국관광연구학회 2016 관광연구저널 Vol.30 No.5

지역상권내 할인마트가 소상공인 이윤에 미치는 영향:충남사례를 중심으로

이민정(Lee, Min-joung),김양중(Kim, Yang-jung) 경기연구원 2019 GRI 연구논총 Vol.21 No.2

VISX S4를 이용한 각막레이저굴절수술 후의 합병증 분석

이민정(Min Joung Lee),위원량(Won Ryang Wee),이진학(Jin Hak Lee),김미금(Mee Kum Kim) 대한검안학회 2006 Annals of optometry and contact lens Vol.5 No.1

목적: VISX S4를 이용한 라식 및 라섹의 수술 중, 수술 후 합병증의 발생률을 알고자 하였다. 대상과 방법: VISX S4 (VISX Inc, Santa Clara, CA)와 M2 (Moria, France) 110 um head로 레이저굴절수술을 시행을 받고, 2개월 이상 추적 관찰한 라식 166안과 20% 알코올을 30초간 적용하여 시행한 라섹 168안을 대상으로 합병증을 굴절 관련, 절편 관련 등으로 나누어 이환율을 분석하였다. 결과: 라식 후 각막편 유리, 각막편 주름, 중심절편경계면출혈이 각 1안(0.60%), 미세선조가 2안(1.21%)에서 발생하였다. 미만성층판각막염 26.5% 중 Grade 2 이상은 4.21%였다. 라섹 술 후 불규칙 상피 회복이 1.79%, Grade 1 이상의 상피세포하 혼탁은 14.88%였고, 이 중 시력저해를 유발한 Grade3 이상의 혼탁은 1.79%였다. 중심부 융기는 1.19%에서 발생하였다. 술 후 구면렌즈 대응치 +0.5 디옵터 초과 교정된 과교정은 라식 후 8.43%, 라섹 후 7.14%였고, 저교정은 라식에서 1.81%, 라섹에서 1.79%였으나 통계적인 유의성은 없었다. 근시재발은 라섹에서만 2.38%였다. 합병증 발생으로 술 전최대교정시력보다 술 후 교정시력이 감소한 경우는 2.10%였다. 결론: VISX S4를 이용한 각막 레이저굴절수술에서 굴절 관련 합병증의 이환율은 라식과 라섹에 따른 유의한 차이가 없었고, 시력을 저해하는 합병증은 2.10% 발생함을 알 수 있었다. Purpose: To investigate the incidence of intraoperative and postoperative complications of LASIK and LASEK using VISX S4. Methods: We retrospectively reviewed data from 334 eyes of 183 patients who followed up at least 2 months. LASIK was done in 166 eyes using VISX S4 and Moria M2 of 110 um head and LASEK was performed in 168 eyes with application of 20% alcohol for 30 seconds. The incidences of refractive-related and flap-related complications were analyzed. Results: Free cap, flap fold, and center interface hemorrhage were found in an eye (0.60%), respectively microstriae was observed in two eyes (1.21%) after LASIK. Diffuse lamellar keratitis were developed in 44 eyes (26.5%). Irregular epithelial healing, subepithelial haze of more than Grade 1, and central island were presented in 3 eyes (1.79%), 25 eyes (14.88%) and 2 eyes (1.19%), respectively. Grade 3 or more of subepithelial haze producing visual disturbance was developed in 3 eyes (1.79%). The incidence of undercorrection and overcorrection was 8.43% and 1.81% in LASIK, and 7.14% and 1.79% in LASEK, respectively, which did not show any significant differences between those two. Conclusions: The incidence of refractive related complications was not significantly different between LASIK and LASEK using VISX S4. The visual decrease that can not be corrected was developed in 2.10% after refractive surgery.