제57차 추계학술대회 및 총회 : 학술대회장 인사

고재경 ( Jai Kyoung Koh ) 대한피부과학회 2005 초록집 Vol.43 No.20

PTBD 관을 통한 담낭암의 피부 착상 전이 1 예

고재경(Jai Kyoung Koh),문기찬(Kee Chan Moon),최지호(Jee Ho Choi),김경진(Kyoung Jin Kim),김은성(Eun Sung Kim),성경제(Kyung Jeh Sung) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.5

The occurrence of metastatic center from the gallbladder to the skin is uncommon and only less than ten cases of distant cutaneous metastases of gallbladder cancer have been reported in literatures. However. cutaneous implantation metastases of gallbladder cancer following laparoscopic cholecystectomy or percutaneous biliary catheter have been described more commonly than distant metastasis. We present herein a case of cutaneous implantation metastasis of gallbladder adenocarcinoma at the sites of percutaneous transhepatic biliary drainage(PTBK).

Micropapular Sarcoidosis 1 예

고재경(Jai Kyoung Koh),문기찬(Kee Chan Moon),최지호(Jee Ho Choi),김경진(Kyoung Jin Kim),배지영(Gee Young Bae),서호석(Ho Seok Suh),성경제(Kyung Jeh Sung) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.5

Cutaneous sarcoidosis occurs in 20-25% of systemic sarcoidosis and be presented without other organ involvement. Most frequent clicical are maculopapule, nodule, plaque, subcutaneous mokule, infiltrative scar and lupus pernio, but uncommon forms including ulcer, alopecia, hypopiminted and micropapular type have been described. Micropapular type is a rare from of cutaneous sarcoidosis with good prognosis. We present a case of generalized micropapular sarcoidosis without other organ involvement

Short Report / 모낭성 피지선 아포크린 분화를 보인 연골양 한관종 1예

고재경(Jai Kyoung Koh),노기영(Kee Young Roh),양정은(Jeong Eun Yang),김형옥(Hyung Ok Kim),강석진(Suk Jin Kang) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.12

Chondroid syringoma is referred as mixed tumor because it has epithelial structure and mesenchymal elements. Mixed tumors could be divided into two distinct types, eccrine and apocrine. Mixed tumor with follicular, sebaceous and apocrine differentiation is considered as an expression of the common embryologic origin of elements of the folliculosebaceous-apocrine unit. A 32-year old man presented with an asymptomatic firm erythematous nodule on the left cheek. Histologically, it showed typical features of chondroid syringoma with tubules exhibiting branching and cystic dilatation in the myxoid and chondroid stroma. Our case is unique in that the tumor arose from follicular infundibulum with follicular, sebacesous and apocrine differentiation. (Korean J Dermatol 2000;38(12): 1673~1676)

선천성 자연 치유성 망상 조직구증

장경애 ( Kyoung Ae Jang ),서치우 ( Chi Woo Suh ),최지호 ( Jee Ho Choi ),성경제 ( Kyung Jeh Sung ),문기찬 ( Kee Chan Moon ),고재경 ( Jai Kyoung Koh ) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.2

Congenital self-healing reticulohistiocytosis (CSHRH) is a rare Langerhans cell disorder showing spontaneous resolution within 3-4 months. By electron microscopy, the identification of many Birbeck granules and laminated dense bodies in the infiltrated cells is mandatory for the diagnosis of CSHRH. We describe a case of congenital self-healing reticulohistiocyt~osis in a 4-month-old male infant.(Koreaa J Dermatol 1999;37(2): 273-275)

갑상선 기능 저하증과 류마티스성 관절염이 동반된 Winkelmann 육아종 1예

장경애 ( Kyoung Ae Jang ),정의창 ( Eui Chang Chung ),최지호 ( Jee Ho Choi ),성경제 ( Kyung Jeh Sung ),문기찬 ( Kee Chan Moon ),고재경 ( Jai Kyoung Koh ) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.1

Winkelmann granuloma is a very rare disorder characterized by histologic findings of perhaps[ic] infiltration, collagen degeneration, and granulomatous inflammation, which usually show palisading features. A number of diseases, especially systemic immunoreactive diseases, are associated with this disorder. We describe a focal neutrophilic necrosis : type of Winkelmann granuloma associated with hypothy- roidism and rheumatoid arthritis. (Korean J Dermatol 1999;37(1) : 119-121)

분아진균증양 농피증으로 사료되는 1예

장경애 ( Kyoung Ae Jang ),장성은 ( Sung Eun Chang ),이허경 ( Hun Kyung Lee ),최지호 ( Jee Ho Choi ),성경제 ( Kyung Jeh Sung ),문기찬 ( Kee Chan Moon ),고재경 ( Jai Kyoung Koh ) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.1

Blastomycosis-like pyoderma is a rare reaction pattern to a superficial bacterial infection in persons with a variety of underlying coniditions, including inflammatory and neoplastic pathologic conditions, and in associaton with a primary immunodeficiency state. We describe a clinically recurrent blastomycosis-like pyoderma on the right ankle area in an otherwise healthy man. (Korean J Dermatol 1999;37(1): 116-118)

중독성 표피 괴사융해증에서 고용량 면역 글로불린 정맥주사의 치료효과에 대한 고찰

김경진(Kyoung Jin Kim),지민선(Min Sun Jee),한만회(Man Heui Han),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.7

Background : Toxic epidermal necrolysis(TEN) is the most dramatic and life-threatening cutaneous drug reaction. However, specific and effective treatment for TEN have not yet been identified. Recently several reports suggested that high dose intravenous immunoglobulin(Ⅳ Ig) treatment has produced good results in patients with TEN. Objective : To analyze the efficacy and side effects of Ⅳ Ig in treatement of TEN. Methods : Ten patients with clinicopathological diagnosis of TEN were treated with IV Ig(1.6-3.4g/㎏), and clinical efficacy and side effects were observed. Results : Nine patients were healed and one died of sepsis. Interruption of further epidermal detachment occurred after an average 3 days from the onset of Ⅳ Ig therapy. Complete wound healing occurred after an average of 14.3 days. The side effects of Ⅳ Ig including headache, myalgia, nausea, transient neutropenia, and coombs positive hemolytic anemia were observed in 4 patients but normalized after cessation of Ⅳ Ig therapy. Three of them showed complete healing of detached skin but died with aggravation of underlying disease. Conclusion : Ⅳ Ig therapy represents a safe and very effective treatment for TEN. Furthermore, intensive care for underlying diseases is also very important for reducing the mortality rate in patients with TEN.

피부 유육종증의 임상 및 병리조직학적 연구

장경애(Kyoung Ae Jang),최지호(Jee Ho Choi),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh),강숙경(Sook Kyung Kang),서호석(Ho Seok Suh),성경제(Kyung Jeh Sung) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.12

Background:Sarcoidosis is a chronic granulomatous inflammatory disorder involving many organs including the skin with various clinical manifestations. Objective:The purpose of this study was to investigate the clinico-pathological characteristics of sarcoidosis. Methods:A total of 19 patients with cutaneous sarcoidosis were enrolled in this study. The hospital charts and histopathological slides of the patients with sarcoidosis diagnosed at Asan Medical Center from 1989 to 1999 were reviewed. Results:1. Three male and sixteen female patients were included(M:F=1:5.3). Age at diagnosis ranged from 4 to 62 years. The mean age was 46 years in male patients and 44.9 years in female patients. 2. Multiple or several(more than 2) skin lesions were common(78.9%). Extremities were the favored sites. Clinically the lesions were presented as subcutaneous nodules, plaques, nodule, macules or papules, patches, psoriasiform, and pitted scar in decreasing order. Cutaneous lesions arising from the scar were present in 3 cases. Six patients(31.6%) complained of systemic symptoms such as fever or weight loss. 3. The systemic involvement was present in 11 cases(57.9%). Lung, hilar lymph nodes, and mediastinal lymph nodes were the most commonly involved organs. 4. Laboratory examinations revealed elevated erythrocyte sedimentation rate(71.4%) and angiotensin converting enzyme(ACE)(90%). In all the patients with elevated level of serum ACE the involvement of intrathorax was present, however one patient with systemic involvement showed normal level of ACE. Serum calcium level was normal in all the patients and the level of CD4/CD8 revealed variable results(1.3 to 3.9). 5. Histopathological evaluation revealed non-caseating epithelioid cell granulomas (100%) with multinucleated giant cells(52.6%) and asteroid body(31.6%). In 11 cases(57.9%), fibrosis was the prominent finding and in two cases(10.5%) partial interstitial necrosis was noted. Histopathologically subcutaneous pattern was predominant in 8 cases(42.1%). The patients with subcutaneous sarcoidosis did not show any specific clinical or laboratory differences from the other types in our study. (Korean J Dermatol 2000;38(12):1583~1589) Conclusion:Cutaneous sarcoidosis showed varied clinical and histopathological manifestations and ran various clinical courses. In cutaneous sarcoidosis women were more commonly involved than in systemic sarcoidosis and more elderly patients were involved in cutaneous sarcoidosis. Extensive work-up for systemic involvement may be mandatory when sarcoidosis is presented with cutaneous lesions or the level of serum ACE is elevated in cutaneous sarcoidosis. The level of CD4/CD8 may be a insignificant laboratory index in sarcoidosis. Also, subcutaneous sarcoidosis may not be a marker of the systemic involvement.

상안검에 발생한 마찰성 탈모증 1예

장경애 ( Kyoung Ae Jang ),성경림 ( Kyung Rim Sung ),성경제 ( Kyung Jeh Sung ),문기찬 ( Kee Chan Moon ),고재경 ( Jai Kyoung Koh ),최지호 ( Jee Ho Choi ) 대한피부과학회 1999 대한피부과학회지 Vol.37 No.2

Each eyelid contains two to three rows of lashes with a total of 100 to 150 lashes. The eyelashes form a first strong link in the protective chain of the eyelids, The partial loss of eyelashes is namely encountered by dermatologists. We describe a 31-year-old man with partial alopecia on the left upper eyelid due to chronic rubbing. We would like to call it friction alopecia. (Korean J Dermatol 1999;37(2): 276-277)