연구소 소개 : 한국에너지기술연구원

유정경 한국화학공학회 2001 NICE Vol.19 No.2

그레이브스병과 동반되어 발생한 연소성 악성빈혈의 치료 1례

유정경,양승,심영석,송준섭 대한소아내분비학회 2012 Annals of Pediatirc Endocrinology & Metabolism Vol.17 No.2

Organ specific autoimmune diseases may occur in the same individual. Type III polyglandular autoimmune disease is defined by the occurrence in the same individual of two or more of the following: autoimmune thyroid disease, pernicious anemia,insulin dependent diabetes, and other organ specific autoimmune diseases not falling into class I or class II categories. A 16-year-old girl developed pernicious anemia during the treatment of Graves'disease. She was diagnosed with Graves' disease 5 years ago and had received methimazole 20 mg/day, but the medication was not well tolerated. Bone marrow findings were compatible with pernicious anemia as macrocytic normochromic red blood cell (RBC) and increased megakaryocyte. The serum value of vitamin B12 was low, and the serum titer of antibody to gastric parietal cell was high. After diagnosis of pernicious anemia, she had treatment by monthly intramuscular vitamin B12 and methimazole (20 mg/day). The values of hemoglobin and RBC indices as well as thyroid function were normalized after 2 months. Vitamin B12 therapy was maintained for 1 year with normal RBC indices. At present, she dose not receive treatment with vitamin B12but she does receive methimazole treatment. We report a case of treatment of pernicious anemia in a 16 year-old girl during treatment for Graves disease. 갑상선 질환을 비롯한 자가면역성 질환은 다인성 및 유전적 경향을 띠고 있으며 HLA-DR과 관련이 있다고 알려져 있다. 다른 자가면역성 질환을 동반하는 경우가 흔하며 1형 당뇨, 류마티스 관절염 , 전신성홍반성루푸스, 쇼그렌증후군,염증성 장질환, 중증근무력증이나 악성빈혈, 백반증, 셀리악병, 자가면역성 간염 및 원형탈모증과 동반되는 경우가 보고되어 있다. 5년 전 그레이브스병 진단 후 메티마졸을 복용하였으나 순응도가 높지 않아 치료가 부진하였던 16세 환자에서 악성빈혈이 동반되어 발생하였다. 환자는 비타민 B_(12) 근육주사와 메티마졸 병행치료 후 악성빈혈 소견 호전되었고 정상적인 갑상선 기능을 보였다. 현재 환자는 비타민 B_(12) 치료를 중단한 후 메티마졸 치료로 외래에서 경과 관찰중이다. 저자들은 그레이브스병과 동반되어 발생한 연소성 악성빈혈에서 기저 질환 조절 후 약물 치료가 필요 없게 된환자 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

HYPERTEXT 원리를 적용한 CAI 코스웨어 개발 및 효과 연구

유정경 한국교육공학회 1993 교육공학연구 Vol.8 No.1

활동지원사를 위한 슈퍼비전 체계 마련 연구 - 서울 **구 S장애인종합복지관 활동보조 사례를 중심으로 -

유정경 ( Jungkyung Yu ),박지혜 ( Jihye Park ),곽철민 ( Cheolmin Kwak ),신은경 ( Eunkyoung Shin ) 한국사회복지슈퍼비전학회 2018 슈퍼비전과 실천연구 Vol.3 No.-

본 연구는 활동지원사의 역량강화를 위한 슈퍼비전의 체계를 구조화하고 활동지원사에게 적용함으로써 마련된 체계의 효과와 한계를 밝히는데 목적이 있다. 이를 위해 사회복지영역에서 사용되는 슈퍼비전 체계를 S장애인종합복지관 중심으로 분석하고 준비, 계획수립, 실행, 평가 단계를 거쳐 활동지원사 슈퍼비전 체계를 마련하였다. 집중 - 개별 - 소집단 - 대집단으로 마련된 슈퍼비전 체계는 현재 재직중인 활동지원사들에게 적용되었다. 집중 슈퍼비전은 슈퍼바이저가 슈퍼바이지의 삶의 과정과 직업의 의미 등을 이해하고 슈퍼바이지와 관계 맺기를 목적으로 한다. 개별 슈퍼비전은 슈퍼바이저가 슈퍼바이지의 서비스 지원 과정에 개입하여 그에 대한 피드백과 접근 방식을 함께 논의하는데 있다. 소집단 슈퍼비전의 목적은 슈퍼바이저와 슈퍼바이지의 신뢰 형성과 슈퍼바이지의 어려움을 경청하고 공감하는데 있다. 대집단 슈퍼비전은 슈퍼바이지가 사회복지 가치를 이해하고 공동의 서비스 목적을 공유토록 하는 것을 목적으로 하였다. 실제 적용과정에서 활동지원사들이 활동지원사로 이루고자 하는 욕구를 확인할 수 있었고 그들이 고민하는 것들 이해할 수 있게 되었다. 그리고 장애인의 개별적인 환경과 특성에 맞춘 개입 방향을 슈퍼바이저와 슈퍼바이지가 함께 계획할 수 있었다. 마지막으로 활동보조가 왜 필요한지 함께 공유함으로써 가치에 기반 한 서비스 수행에 대해 고민해볼 수 있었다는데 의의가 있다. The purpose of this study is to set up an adequate supervision system for the strengthening of personal assistants for the disabled(PDA)’s abilities and determine the effects and limits of the system. The supervision system for the PAD has been build up through several steps (preparation → planning → implementation → evaluation, feedback) based on the existing supervision system for social workers which is widely used in social service field, especially using the example of Seobu Welfare Center for Persons with Disabilities. The supervision system has been provided to PAD in active service as four different types. First, the focused supervision is to build relationship between a supervisor and a supervisee, and to help the supervisor understand more the life of supervisee. Secondly, the individual supervision is supervisors’ intervention against individual case. Through the supervision, supervisees get feedback or information concerning work skills from supervisors. Third, the purpose of the small group supervision is to listen carefully to supervisees and empathize with them, and to build up mutual trust in partnership. Fourth, the large group supervision is to share the values of the social welfare with supervisees and to make them understand the common goal of PAS(Personal Assistance Service) for eventually improving quality of life of the disabled. As a result, by applying the supervision system, supervisors discovered supervisees’ needs, challenges, and difficulties as a worker of care service. And also supervisors and supervisees could make plans together about the support direction according to individual properties and environment of the disabled. In short, this study is meaningful in that it emphasized the necessity of PAS and the importance of value based service.

천식 소아에서 혈청 렙틴과 만니톨 기관지 과민성과의 관계

유정경 ( Jung Kyung Yoo ),신재영 ( Jae Young Shin ),유정섭 ( Jueng Sup You ),정수인 ( Soo In Jeong ),송준섭 ( Joon Sup Song ),양승 ( Seong Yang ),황일태 ( Il Tae Hwang ),이하백 ( Ha Baik Lee ),백혜성 ( Hey Sung Ba다 ) 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.1

Purpose: Epidemiological data indicate that obesity is a risk factor in asthma, however effects related to obesity and adipokines on airway inflammation and bronchial hyper-responsiveness (BHR) have not yet been demonstrated in the human airway. The aim of this study was to investigate the relationship between serum adipokine levels and BHR to mannitol in asthmatic children. Methods: Serum adipokine levels were measured and pulmonary function tests were perfomed: baseline, postbronchodilator inhalation, methacholine inhalation, and mannitol inhalation. The response to mannitol was expressed as the dose causing a 15% decrease in forced expiratory volume in one second (FEV1) (PD15), and as the response-dose ratio (RDR) (% fall in FEV1/cumulative dose). Results: Sixty-nine prepubertal children between the ages of 6 and 10 years were participated in the study. They comprised asthmatic children (n=40) and healthy (n=29). Twenty-two subjects (55.5%) with asthma had a positive mannitol bronchial provocation test (BPT) result. The body mass index (BMI) was higher in those asthmatics with positive mannitol BPTs than in asthmatics with negative mannitol BPTs and in the control group (19.30 kg/m2 vs. 17.60 kg/m2 vs. 17.93 kg/m2, P=0.035, P=0.046). Serum leptin levels were also significantly higher in asthmatics with positive mannitol BPTs than in asthmatics with negative mannitol BPTs and in the control group (10.58 ng/mL vs. 5.49 ng/mL vs. 6.75 ng/mL, P=0.002, P=0.016). Leptin values were significantly associated with a PD15 (r=.0.498, P=0.022) and RDR to mannitol (r=0.346, P=0.033) in asthmatic children after adjustment for BMI. Conclusion: Serum leptin levels were significantly associated with BHR to mannitol in asthmatic children. (Allergy Asthma Respir Dis 2014;2:30-37)

만삭 부당경량아에서의 인슐린, 렙틴, IGF-I, 아디포넥틴, 그렐린의 호르몬 변화와 따라잡기 성장과의 관계

이윤영,유정경,박홍규,양승,황일태 대한소아내분비학회 2011 Annals of Pediatirc Endocrinology & Metabolism Vol.16 No.2

Purpose:The aim of the study was to investigate postnatal changes in growth and insulin, leptin, IGF-I, adiponectin, and ghrelin, and to examine the relationship of these hormones with catch-up growth in full-term small for gestational age (SGA) infants. Methods: SGA was defined as a birth weight less than the ten percentile. Weight and height were measured at birth, 1 month, 6 months, 1 year, and 2 years of age in 70 SGA infants (40 females and 30 males). The infants were subdivided according to their weight and height catch-up growth (CUG) at 2 years old. CUG is defined as reaching a standard deviation score (SDS) of ˃ -2 SDS. Blood samples were serially taken for insulin, leptin, insulin- like growth factor (IGF)-I, adiponectin, and ghrelin. Results: 1) Dramatic CUG for weight and height occurred during the first year of life; weight and height growth gain decreased thereafter. 2) Non-catch-up growth (NCUG) infants showed more decreased weight and height growth gain than CUG infants between the first and second year of life. 3) Weight CUG was 77.1% and height CUG was 75.8% in the SGA infants. 4) Weight CUG infants showed significantly higher leptin and ghrelin levels than in weight NCUG infants at the age of 1 year (P ˂0.05). 5) Height CUG infants showed significantly higher leptin and ghrelin levels than in height NCUG infants at the age of 1 year (P ˂0.05). Conclusion: CUG for weight and height occurred during the first year of life and growth velocity decreased thereafter. Significant corresponding changes occurred with regard to serum leptin and ghrelin.(J Korean Soc Pediatr Endocrinol 2011;16:112-118)

Chemical Colitis Caused by Hydrogen Peroxide Enema in a Child : A Case Report and Literature Review

이준상,유정경 대한응급의학회 2017 大韓應急醫學會誌 Vol.28 No.2

A 2-year-old girl, previously healthy, was brought to our emergency department due to abdominal pain (cramping), following recurrent hematochezia after an accidental hydrogen peroxide enema (35%, 5 mL) by her caregiver. She was hospitalized and admitted to the pediatric department and treated with NPO (nil per os), intravenous fluid, and parenteral antibiotic therapy. Laboratory, radiologic, endoscopic evaluations were performed. She was discharged with full recovery 10 days after admission. This may be the first case report of acute chemical colitis by accidental hydrogen peroxide enema in children.

길버트 증후군 환아에서 조영제 사용 후 발생한 지속적 황달 증례

신우철 ( Woochul Shin ),신석표 ( Suk Pyo Shin ),한상학 ( Sang Hak Han ),유정경 ( Jung Kyung Yoo ) 대한췌장담도학회 2021 대한췌담도학회지 Vol.26 No.3

저자들은 길버트 증후군 환아에서 조영제 사용 후 발생한 지속적 황달 증례를 보고하는 바이다. 이는 비교적 드문 증례로, 임상에서의 꾸준한 관찰이 필요하다. This paper reports a child with Gilbert's syndrome who underwent cholecystectomy and endoscopic retrograde cholangiopancreatography, magnetic resonance cholangiopancreaticography to removal of the gallstones, then experienced increase in bilirubin of unknown cause. Korean J Pancreas Biliary Tract 2021;26(3):200-204