육미지황탕(六味地黃湯),택사탕(澤瀉湯), 실비음(實脾飮)이 메산지움세포 증식, Fibronectin 합성 및 MHC-class II 발현에 미치는 영향(影響)

안세영,두호경,이진신,Ahn, Sae-Young,Doo, Ho-Kyung,Lee, Jin-Sin 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.3

Objective : To analyze the effects of Yukmijihwang-tang, Taeksa-tang, Silbi-um on mesangial cell proliferation, fibronectin synthesis and MHC-class II expression. Methods : Laboratory studies were performed with the method of surface enzyme immunoassays or flow cytometry after addition of peripheral blood mononuclear cells(PBMC) supernatants treated with medications using the cultured human mesangial cells. Results : 1. Silbi-um produces more suppressive effect than control group and hydrocortisone group on the mesangial cell proliferation. In Yukmijihwang-tang, Taeksa-tang and Silbi-um, mesangial cell proliferation significantly decreased than in hydrocortisone group 2. In the 'without fetal bovine serum' study, Yukmijihwang-tang take more suppressive effect than Control group on the fibronectin synthesis. In the 'with fetal bovine serum' study, Yukmijihwang-tang, Taeksa-tang, Silbi-um all have suppressive effect, but it hasn' t any statistical significance. 3. Yukmijihwang-tang, Taeksa-tang, Silbi-um all have a suppressive effect on the MHC-class II expression. Conclusions : Herb medicine generally show a suppressive effect on the suppression of the mesangial cell proliferation, fibronectin synthesis and MHC-class II expression.

임신 중 우울증상에 대한 임상연구

최세경 ( Sae Kyung Choi ),안세영 ( Se Young Ahn ),신종철 ( Jong Chul Shin ),장동규 ( Dong Gyu Jang ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.11

목적: 본 연구는 임신 중 발생하는 우울증의 빈도 및 이에 영향을 줄 수 있는 요인들을 분석하고자 하였다. 연구 방법: 2008년 3월 1일부터 2008년 5월 31일까지 강남성모병원에서 산전진찰을 받은 여성 중 우울증 연구에 동의한 205명의 산모를 대상으로 인구-사회학적 정보 및 임신과 관련된 설문지와 산후우울증 평가 척도 (EPDS)를 작성하도록 하였다. 통계분석은 SPSS 12.0을 이용하여 chi-square test 및 Fisher`s extract test를 통해 산출하였고, P값이 0.05 미만인 경우에 통계적으로 유의하다고 하였다. 결과: 205명의 산모의 EPDS 점수는 평균 7.3±4.2이었으며, 26.4%인 54명은 10 이상으로 우울상태에 해당되었다. 임신의 각분기별 비교에서 우울증 발생 빈도는 차이를 보이지 않았다 (25.7% vs. 29.0% vs. 25.0%, P=0.844). 또한 인구-사회학적 요소 중 우울증 발생에 의미있게 영향을 주는 요인은 발견되지 않았다. 임신과 관련된 요소 중에서는, 임신을 계획하지 않았던 경우에 우울증 발생율이 통계학적으로 유의하게 높았으며 (34.6% vs. 21.0%, P=0.036), 이전 임신 시 사산이나 태아의 선천성기형 등 문제가 있었던 경우도 우울증 발생과 연관이 있는 것으로 나타났다 (56.3% vs. 23.8%, P=0.014). 결론: 본 연구는 임신 중 우울증상에 대한 첫 임상 분석이라는 데 큰 의의가 있으며, 이를 바탕으로 우울증에 대한 보다 적극적인 관리를 해야 할 것이다. Objective: To examine the incidence of the depressive symptoms during pregnancy and the socio-demographic and obstetric factors associated with depression. Methods: Two hundred five women who had received antenatal care at Kangnam St. Mary`s Hospital from March 2008 to May 2008 completed the questionnaire related to socio-demographic characteristics and Edinburgh Postnatal Depression Scale (EPDS). Statistics were performed using chi-square test and Fisher`s extract test (SPSS 12.0). Results were considered statistically significant for P-values<0.05. Results: Of 205 pregnant women, the mean score of EPDS was 7.3±4.2.54 of 205 women (26.5%) scored more than 10 point which is the cutoff value to define depressive symptoms. The incidences of depressive symptoms were not significantly different by the trimester (25.7% vs. 29.0% vs. 25.0%, P<0.844). There were no significant socio-geographic factors associated with depressive symptoms. In cases of unexpected pregnancies, the incidence of depressive symptoms was significantly high (34.6% vs. 21.0%, P=0.036), and the women who have problems of previous pregnancies scored significantly higher EPDS (56.3% vs. 23.8%, P=0.014). Conclusion: This study was the first report about the depression symptoms during pregnancy. Based on this study, we have to focus on and manage depression symptoms related to pregnancy.

목적지의 가족집합을 이용한 향상된 ZigBee 라우팅 알고리즘

신현재(Hyun-Jae Shin),안세영(Sae-Young Ahn),조영준(Young-Jun Jo),안순신(Sun-Shin An) 대한전기학회 2010 전기학회논문지 Vol.59 No.12

Hierarchical tree routing is a inefficient routing method of transmitting data in a wireless sensor network. Zigbee routing which is made to improve inefficiency of the hierarchical tree routing only fulfills the tree routing when a destination node don't exists in neighbor nodes of a router. We suggest a TFSR algorithm that is improved more than the zigbee routing. The TFSR algorithm generates a family set included a parent node and child nodes and over of a destination node, and uses this information. According to simulation results, the TFSR algorithm reduce routing costs over 30 percent in comparison with the hierarchical tree routing and the zigbee routing.

Scheduling Wake Up time 을 갖는 ZigBee tree network routing

윤세종(Yoon Se Jong),안세영(Ahn Sae Young),안재영(Ahn Jae Young),안순신(An Sun Shin) 한국통신학회 2009 한국통신학회 학술대회논문집 Vol.2009 No.11

黃耆 및 蜜炙黃耆煎湯液이 Gentamicin Sulfate로 誘發된 白鼠의 急性 賢不全에 미치는 影響

陸玄碩,杜鎬京,安世永 慶熙大學校韓醫科大學韓醫學硏究所 1998 慶熙韓醫大論文集 Vol.21 No.1

This artide is to investigate what effects Astragalus membranaceus BUNGE and honey-fried Astragalus membranaceus BUNGE have on Rats with Acute Renal Failure(ARF) induced by Gentamicin Sulfate. So this experimental research was focused on measuring ① the level of Creatinine, Blood Urea Nitrogen(BUN). Glutamic Oxaloacetic Transaminase(GOT), Glutamic Pyruvic Transaminase(GPT), Total Protein, Sodium(Na+), Potassium(K+), Chloride(Cl-) in the Serum, ② the level of Protein, Blood, Sodium(Na+), Potassium(K+), Chloride(Cl-), pH, Specific Gravity and Volume in the Urine and ③ Intake Water. The results were summarized as follows : 1. As to Astragalus membranaceus BUNGE, while the concentrations of Blood Urea Nitrogen(BUN), Creatinine, Glutamic Oxaloacetic Transaminase(GOT) in the Serum were significantly decreased the level of Sodium(Na+) in the Urine was significantly increased and those of Total protein in the Serum, protein and Blood in the Urine were partially improved. 2. As to Honey-fried Astragalus membranaceus BUNGE, while the concentrations of Blood Urea Nitrogen(BUN), Creatinine, Glutamic Pyruvic Transaminase(GPT) in the Serum were significantly decreased the level of Potassium(K+) in the Urine was significantly increased and those of Total Protein in the Serum, Protein and Blood in the Urine were partially improved. According to the above results, it is shown that Astragalus membranaceus BUNGE and Honey-fried Astragalus membranaceus BUNGE ① the Glomerular Filtration Rate(GFR) is partially increased and ② the function of tubular reabsorption is partially improved. It is concluded that both Astragalus membranaceus BUNGE and Honey-fried Astragalus membranaceus BUNGE maybe be conductive to the treatment of Acute Renal Failure(ARF).

"前立腺肥大症" 關한 東西醫學的 考察

安永敏,安世永,曺東鉉,杜鎬京 대한한방성인병학회 1995 韓方成人病學會誌 Vol.1 No.1

BPH (Benign prostatic hyperplasia, Benign prostatic hypertrophy) mainly occurs in over fifties and more in the western than in the estern. But the aflection of the disease in Korea is increasing step by step in accordance with current clothing, food, housing and living enviornmental improvement, the increasing of the old population and the increasing information on this disease. So after studying many books on the cause of this ailment, clinical symptom, diagnosis, and treatment in terms of Western medicine and pathologic mechanism, identification of the patterns of BPH in terms of Oriental medicine, which is the most frequent cause of dysuria, I have come to the conclusion as the following, 1. BPH mostly occurs in over fifties and affects about 80% of over eighties. 2. The accurate cause of the disease has not been known yet, but is considered age-inducing Estrogen and Testosteron disharmony and the change of the interaction between interstitium and epithelium. TURP(transurethral prostatic resection), which occupies 95% of Western therapy, has serious side effect like bleeding, shock, and sequential death. Operation therapy is controversial because most affected pations are the old accompanying Hypertention, DM, cranial and cardiac vascular disease and chronic pulmonary disease. So patients' intrinsic adjusting ability and anesthetic problem, operating effectiveness are important factors in operation. α-adrenergic receptor blocker or Anti-androgen agent is used as medication but is not recomendable as long-term therapy, because of the side effect like hypertention, anaphrodisia, orthostatic impotence, gynecomastia and so on. All the more, the symptom might reapper if patients stop taking the medicine. So it is important and urgent to develop a new therapy. 4. BPH could be classified into Yung-Pae, Sobyonbultong, Sobyonbulli, Limbyong and is caused by the function disorder of Triple burners, which are composed of spleen, lung, kidney, or Liver Qj stagnant, or Blood stagnant Blood pocculusive obstruction. 5. The type could be classified into Kidney Yang deficiency, Kidney Yin deficiency, Middle burner Energy deficiency, Damp-Heat in the bladder Lung Hot Qj Stagnant, Liver Qj stagnant. 6. Available are Warming and tonifying Kidney Yang, improving Qj and Water circulation, moisturing and cooling Emptg-fire blazing tonifying Middle burner energy, cooling and improving Fluid circulation, improving Qj circulation, Cooling and emitting Lung hot as treating priciples. 7. And we can applied Acup-Tx, Qj-Kong Tx, Manipulation therapy, Kinesitheraphy, Attachment therapy, fumigation and sitz-bath therapy after watching symptoms and finding the cause, implemeting identification of patterns.